메뉴 건너뛰기




Volumn 7, Issue 4-5, 2007, Pages 453-465

Differential genome analyses of metabolic enzymes in pseudomonas aeruginosa for drug target identification

Author keywords

Comparative microbial genomics; Homo sapiens; Homology; KEGG; LpxC; MODELLER; Potential drug targets; Pseudomonas aeruginosa

Indexed keywords

ACETYL COENZYME A ACETYLTRANSFERASE; ALANINE RACEMASE; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; ALKALINE PHOSPHATASE; ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE; ANTHRANILATE SYNTHASE; BACTERIAL ENZYME; BETA LACTAMASE; CATECHOL 1,2 DIOXYGENASE; CITRATE LYASE BETA CHAIN; DEXTRO ALANINE DEXTRO ALANINE LIGASE; GLUCOSE 1 PHOSPHATE THYMIDYLTRANSFERASE; GLUCOSYLTRANSFERASE; GLUTAMATE AMMONIA LIGASE; LYASE; METHYLTRANSFERASE; NITRATE REDUCTASE; PHOSPHOTRANSFERASE; POLYHYDROXYALKANOATE SYNTHASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; QUINOPROTEIN ALCOHOL DEHYDROGENASE; SERINE PROTEINASE; TETRAACYLDISACCHARIDE 4' KINASE; TRANSFERASE; UNCLASSIFIED DRUG;

EID: 38949196018     PISSN: 13866338     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (55)

References (33)
  • 2
    • 0031610907 scopus 로고    scopus 로고
    • Bacterial iron transport: Mechanisms genetics, and regulation
    • Braun, V., Hantke, K. and Köster, W. (1998). Bacterial iron transport: Mechanisms genetics, and regulation. Met. Ions Biol. Syst. 35, 67-145.
    • (1998) Met. Ions Biol. Syst , vol.35 , pp. 67-145
    • Braun, V.1    Hantke, K.2    Köster, W.3
  • 4
    • 0020065258 scopus 로고
    • Fractionation and characterization of the phosphoenolpyruvate: Fructose 1-phosphotransferase system from Pseudomonas aeruginosa
    • Durham, D. R. and Phibbs, P. V. Jr. (1982). Fractionation and characterization of the phosphoenolpyruvate: Fructose 1-phosphotransferase system from Pseudomonas aeruginosa. J. Bacteriol. 149, 534-541.
    • (1982) J. Bacteriol , vol.149 , pp. 534-541
    • Durham, D.R.1    Phibbs Jr., P.V.2
  • 5
    • 0032728399 scopus 로고    scopus 로고
    • Searching for drug targets in microbial genomes
    • Galperin, M. Y. and Koonin, E. V. (1999). Searching for drug targets in microbial genomes. Curr. Opin. Biotechnol. 10, 571-578.
    • (1999) Curr. Opin. Biotechnol , vol.10 , pp. 571-578
    • Galperin, M.Y.1    Koonin, E.V.2
  • 6
    • 6044244615 scopus 로고    scopus 로고
    • Conserved hypothetical' proteins: Prioritization of targets for experimental study
    • Galperin, M. Y. and Koonin, E. V. (2004). 'Conserved hypothetical' proteins: Prioritization of targets for experimental study. Nucleic Acids Res. 32, 5452-5463.
    • (2004) Nucleic Acids Res , vol.32 , pp. 5452-5463
    • Galperin, M.Y.1    Koonin, E.V.2
  • 8
    • 0032502899 scopus 로고    scopus 로고
    • Differential genome analysis applied to the species-specific features of Helicobacter pylori
    • Huynen, M., Dandekar, T. and Bork, P. (1998). Differential genome analysis applied to the species-specific features of Helicobacter pylori. FEBS Lett. 426, 1-5.
    • (1998) FEBS Lett , vol.426 , pp. 1-5
    • Huynen, M.1    Dandekar, T.2    Bork, P.3
  • 9
    • 0028906201 scopus 로고
    • An estimation of minimal genome size required for life
    • Itaya, M. (1995). An estimation of minimal genome size required for life. FEBS Lett. 362, 257-260.
    • (1995) FEBS Lett , vol.362 , pp. 257-260
    • Itaya, M.1
  • 12
    • 0035895351 scopus 로고    scopus 로고
    • Site-directed mutagenesis of the bacterial metalloamidase UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC). Identification of the zinc binding site
    • Jackman, J. E., Raetz, C. R. H. and Fierke, C. A. (2001). Site-directed mutagenesis of the bacterial metalloamidase UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC). Identification of the zinc binding site. Biochemistry 40, 514-523.
    • (2001) Biochemistry , vol.40 , pp. 514-523
    • Jackman, J.E.1    Raetz, C.R.H.2    Fierke, C.A.3
  • 14
    • 0345668475 scopus 로고    scopus 로고
    • Essential Bacillus subtilis genes
    • Kobayashi, K., et al. (2003). Essential Bacillus subtilis genes. Proc. Natl. Acad. Sci. USA 100, 4678-4683.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 4678-4683
    • Kobayashi, K.1
  • 15
    • 0032102671 scopus 로고    scopus 로고
    • Beyond complete genomes: From sequence to structure and function
    • Koonin, E. V., Tatusov, R. L. and Galperin, M. Y. (1998). Beyond complete genomes: From sequence to structure and function. Curr. Opin. Struct. Biol. 8, 355-363.
    • (1998) Curr. Opin. Struct. Biol , vol.8 , pp. 355-363
    • Koonin, E.V.1    Tatusov, R.L.2    Galperin, M.Y.3
  • 16
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • The Genome International Consortium
    • Lander, E. S., et al., The Genome International Consortium (2001). Initial sequencing and analysis of the human genome. Nature 409, 860-921.
    • (2001) Nature , vol.409 , pp. 860-921
    • Lander, E.S.1
  • 18
    • 0035038011 scopus 로고    scopus 로고
    • Drug targeting Mycobacterium tuberculosis cell wall synthesis: Genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose
    • Ma, Y., Stern, R. J., Scherman, M. S., Vissa, V. D., Yan, W., Jones, V. C., Zhang, F., Franzblau, S. G., Lewis, W. H. and McNeil, M. R. (2001). Drug targeting Mycobacterium tuberculosis cell wall synthesis: genetics of dTDP-rhamnose synthetic enzymes and development of a microtiter plate-based screen for inhibitors of conversion of dTDP-glucose to dTDP-rhamnose. Antimicrob. Agents Chemother. 45, 1407-1416.
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 1407-1416
    • Ma, Y.1    Stern, R.J.2    Scherman, M.S.3    Vissa, V.D.4    Yan, W.5    Jones, V.C.6    Zhang, F.7    Franzblau, S.G.8    Lewis, W.H.9    McNeil, M.R.10
  • 20
    • 0038779197 scopus 로고    scopus 로고
    • Genetic strategies for antibacterial drug discovery
    • Miesel, L., Greene, J. and Black, T. A. (2003). Genetic strategies for antibacterial drug discovery. Nat. Rev. Genet. 4, 442-456.
    • (2003) Nat. Rev. Genet , vol.4 , pp. 442-456
    • Miesel, L.1    Greene, J.2    Black, T.A.3
  • 21
    • 0029789824 scopus 로고    scopus 로고
    • A minimal gene set for cellular life derived by comparison of complete bacterial genomes
    • Mushegian, A. R. and Koonin, E. V. (1996). A minimal gene set for cellular life derived by comparison of complete bacterial genomes. Proc. Natl. Acad. Sci. USA 93, 10268-10273.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 10268-10273
    • Mushegian, A.R.1    Koonin, E.V.2
  • 22
    • 0031948133 scopus 로고    scopus 로고
    • Antibiotic resistance caused by gram-negative multidrug efflux pumps
    • Nikaido, H. (1998). Antibiotic resistance caused by gram-negative multidrug efflux pumps. Clin. Infect. Dis. 27, S32-S41.
    • (1998) Clin. Infect. Dis , vol.27
    • Nikaido, H.1
  • 23
    • 0032833434 scopus 로고    scopus 로고
    • Amino acid-mediated induction of the basic amino acid-specific outer membrane porin OprD from Pseudomonas aeruginosa
    • Ochs, M. M., Lu, C.-D., Hancock, R. E. W. and Abdelal, A. T. (1999). Amino acid-mediated induction of the basic amino acid-specific outer membrane porin OprD from Pseudomonas aeruginosa. J. Bacteriol. 181, 5426-5432.
    • (1999) J. Bacteriol , vol.181 , pp. 5426-5432
    • Ochs, M.M.1    Lu, C.-D.2    Hancock, R.E.W.3    Abdelal, A.T.4
  • 24
    • 10044239624 scopus 로고    scopus 로고
    • A novel genomics approach for the identification of drug targets in pathogens, with special reference to Pseudomonas aeruginosa
    • Sakharkar, K. R., Sakharkar, M. K. and Chow, V. T. (2004). A novel genomics approach for the identification of drug targets in pathogens, with special reference to Pseudomonas aeruginosa. In Silico Biol. 4, 0028.
    • (2004) In Silico Biol , vol.4 , pp. 0028
    • Sakharkar, K.R.1    Sakharkar, M.K.2    Chow, V.T.3
  • 25
    • 33646034288 scopus 로고    scopus 로고
    • Gene fusion in Helicobacter pylori: Making the ends meet
    • Sakharkar, K. R., Sakharkar, M. K. and Chow, V. T. (2006). Gene fusion in Helicobacter pylori: Making the ends meet. Antonie Van Leeuwenhoek 89, 169-180.
    • (2006) Antonie Van Leeuwenhoek , vol.89 , pp. 169-180
    • Sakharkar, K.R.1    Sakharkar, M.K.2    Chow, V.T.3
  • 26
  • 27
    • 0028882959 scopus 로고
    • Structural genes for salicylate biosynthesis from chorismate in Pseudomonas aeruginosa
    • Serino, L., Reimmann, C., Baur, H., Beyeler, M., Visca, P. and Haas, D. (1995). Structural genes for salicylate biosynthesis from chorismate in Pseudomonas aeruginosa. Mol. Gen. Genet. 249, 217-228.
    • (1995) Mol. Gen. Genet , vol.249 , pp. 217-228
    • Serino, L.1    Reimmann, C.2    Baur, H.3    Beyeler, M.4    Visca, P.5    Haas, D.6
  • 29
    • 0034739007 scopus 로고    scopus 로고
    • Stover, C. K., Pham, X. Q., Erwin, A. L., Mizoguchi, S. D., Warrener, P., Hickey, M. J., Brinkman, F. S., Hufnagle, W. O., Kowalik, D. J., Lagrou, M., Garber, R. L., Goltry, L., Tolentino, E., Westbrock-Wadman, S., Yuan, Y., Brody, L. L., Coulter, S. N., Folger, K. R., Kas, A., Larbig, K., Lim, R., Smith, K., Spencer, D., Wong, G. K., Wu, Z., Paulsen, I. T., Reizer, J., Saier, M. H., Hancock, R. E., Lory, S. and Olson, M. V. (2000). Complete genome sequence of Pseudomonas aeruginosa PAO1: An opportunistic pathogen. Nature 406, 959-964.
    • Stover, C. K., Pham, X. Q., Erwin, A. L., Mizoguchi, S. D., Warrener, P., Hickey, M. J., Brinkman, F. S., Hufnagle, W. O., Kowalik, D. J., Lagrou, M., Garber, R. L., Goltry, L., Tolentino, E., Westbrock-Wadman, S., Yuan, Y., Brody, L. L., Coulter, S. N., Folger, K. R., Kas, A., Larbig, K., Lim, R., Smith, K., Spencer, D., Wong, G. K., Wu, Z., Paulsen, I. T., Reizer, J., Saier, M. H., Hancock, R. E., Lory, S. and Olson, M. V. (2000). Complete genome sequence of Pseudomonas aeruginosa PAO1: An opportunistic pathogen. Nature 406, 959-964.
  • 30
    • 0033800818 scopus 로고    scopus 로고
    • Characterization of the alanine racemases from Pseudomonas aeruginosa PAO1
    • Strych, U., Huang, H. C., Krause, K. L. and Benedik, M. J. (2000). Characterization of the alanine racemases from Pseudomonas aeruginosa PAO1. Curr. Microbiol. 41, 290-294.
    • (2000) Curr. Microbiol , vol.41 , pp. 290-294
    • Strych, U.1    Huang, H.C.2    Krause, K.L.3    Benedik, M.J.4
  • 31
    • 0030660581 scopus 로고    scopus 로고
    • A genomic perspective on protein families
    • Tatusov, R. L., Koonin, E. V. and Lipman, D. J. (1997). A genomic perspective on protein families. Science 278, 631-637.
    • (1997) Science , vol.278 , pp. 631-637
    • Tatusov, R.L.1    Koonin, E.V.2    Lipman, D.J.3
  • 32
    • 0027968068 scopus 로고
    • CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
    • Thompson, J. D., Higgins, D. G. and Gibson, T. J. (1994). CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22, 4673-4680.
    • (1994) Nucleic Acids Res , vol.22 , pp. 4673-4680
    • Thompson, J.D.1    Higgins, D.G.2    Gibson, T.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.