Discovery of potent dual PPARα agonists/CB1 ligands

ACS Medicinal Chemistry Letters

Volumn 2, Issue 11, 2011, Pages 793-797

  Pérez Fernández, Ruth ^a   Fresno, Nieves ^a   MacÍas González, Manuel ^b   Elguero, José ^a   Decara, Juan ^c,d   Girón, Rocío ^e   Rodríguez Álvarez, Ana ^e   Martín, María Isabel ^e   Rodríguez De Fonseca, Fernando ^c,d   Goya, Pilar ^a  

^a INSTITUTO DE QUÍMICA MÉDICA   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LA VICTORIA   (Spain)

^c HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

^d Instituto de Salud Carlos III   (Spain)

^e UNIVERSIDAD REY JUAN CARLOS   (Spain)

Author keywords

cannabinoids; Dual ligands; fibrates; neuroprotective; PPAR ; rimonabant

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID 1 RECEPTOR AGONIST; FIBRIC ACID DERIVATIVE; N OLEOYLETHANOLAMINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PIRINIXIC ACID; RIMONABANT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

EID: 80955150852     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml200091q     Document Type: Article

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