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Volumn 46, Issue 12, 2011, Pages 5817-5824

Synthesis and apoptosis inducing ability of new anilino substituted pyrimidine sulfonamides as potential anticancer agents

(10) Kamal, Ahmed a,b Dastagiri, D a Janaki Ramaiah, M a Surendranadha Reddy, J a Vijaya Bharathi, E a Kashi Reddy, M a Victor Prem Sagar, M a Lakshminarayan Reddy, T a Pushpavalli, S N C V L a Pal Bhadra, Manika a

a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY (India)

b KING SAUD UNIVERSITY (Saudi Arabia)

Author keywords

Akt; Anilino substituted pyrimidines; Apoptosis; Caspases; Sulfonamides

Indexed keywords

3,4 DIMETHOXY N[4 METHYL 3 [4 (3,4,5 TRIMETHOXYPHENYL)PYRIMIDIN 2 YLAMINO]PHENYL]BENZENE SULFONAMIDE; 4 CHLORO N[4 METHYL 3 [4 (PYRIDIN 4 YL)PYRIMIDIN 2 YLAMINO]PHENYL]BENZENE SULFONAMIDE; 4 METHOXY N[4 METHYL 3 [4 (3,4,5 TRIMETHOXYPHENYL)PYRIMIDIN 2 YLAMINO]PHENYL]BENZENE SULFONAMIDE; AKT1 PROTEIN; ANTINEOPLASTIC AGENT; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; IMATINIB; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N[4 METHYL 3 [4 (3,4,5 TRIMETHOXYPHENYL)PYRIMIDIN 2 YLAMINO]PHENYL]BIPHENYL 4 SULFONAMIDE; N[4 METHYL 3 [4 (3,4,5 TRIMETHOXYPHENYL)PYRIMIDIN 2 YLAMINO]PHENYL]NAPHTHALENE 2 SULFONAMIDE; N[4 METHYL 3 [4 (PYRIDIN 4 YL)PYRIMIDIN 2 YLAMINO]PHENYL]BIPHENYL 4 SULFONAMIDE; N[4 METHYL 3 [4 (PYRIDIN 4 YL)PYRIMIDIN 2 YLAMINO]PHENYL]NAPHTHALENE 2 SULFONAMIDE; N[4 METHYL 3 [4 (PYRIDIN 4 YL)PYRIMIDIN 2 YLAMINO]PHENYL]QUINOLINE 3 SULFONAMIDE; PROTEIN KINASE B; PYRIMIDINE DERIVATIVE; SERINE; SULFONAMIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SYNTHESIS; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IC 50; TRANSCRIPTION REGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CYCLIN D1; DOWN-REGULATION; G1 PHASE; HUMANS; NEOPLASMS; NF-KAPPA B; PYRIMIDINES; SULFONAMIDES;

EID: 80955148857 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2011.09.039 Document Type: Article

Times cited : (61)

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