A novel stereo-selective sulfonylurea, 1-[1-(4-aminobenzoyl)-2,3-dihydro-1H-indol-6-sulfonyl]-4-phenyl- imidazolidin-2-one, has antitumor efficacy in in vitro and in vivo tumor models

Biochemical Pharmacology

Volumn 64, Issue 3, 2002, Pages 473-480

  Lee, Chang Woo ^a   Hong, Dong Ho ^a   Han, Sang Bae ^a   Jung, Sang Hun ^b   Kim, Hyung Chin ^a   Fine, Robert L ^c   Lee, Sang Han ^a   Kim, Hwan Mook ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chungnam National University   (South Korea)

^c College of Physicians and Surgeons ^*  (United States)

Author keywords

Antitumor agents; In vitro and in vivo tumor models; Stereo selective; Sulfonylureas

Indexed keywords

1 [1 (4 AMINOBENZOYL) 2,3 DIHYDRO 1H INDOL 6 SULFONYL] 4 PHENYLIMIDAZOLIDIN 2 ONE; DOXORUBICIN; DW 2143; DW 2282; SULFONYLUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CANCER CELL; CANCER INHIBITION; CELL TYPE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG SPECIFICITY; FEMALE; HUMAN; HUMAN CELL; HYPOGLYCEMIA; IN VITRO STUDY; IN VIVO STUDY; ISOMER; LEUKEMIA L 1210; NONHUMAN; PRIORITY JOURNAL; RACEMIC MIXTURE; TREATMENT OUTCOME; TUMOR MODEL; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIVISION; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; IMIDAZOLES; MICE; MICE, INBRED BALB C; MICE, NUDE; MOLECULAR CONFORMATION; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; SULFONES; TREATMENT OUTCOME; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0036685196     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)01105-X     Document Type: Article

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