Novel halogenated sulfonamides inhibit the growth of multidrug resistant MCF-7/ADR cancer cells

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 13, 1999, Pages 1843-1846

  Medina, Julio C ^a   Roche, Daniel ^a   Shan, Bei ^a   Learned, R Marc ^a   Frankmoelle, Walter P ^a   Clark, David L ^a   Rosen, Terry ^a   Jaen, Juan C ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZENESULFONAMIDE DERIVATIVE; SULFONAMIDE;

ARTICLE; CANCER CELL; CANCER INHIBITION; CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MULTIDRUG RESISTANCE; STRUCTURE ACTIVITY RELATION;

DRUG RESISTANCE, MULTIPLE; GROWTH INHIBITORS; HALOGENS; HELA CELLS; HUMANS; SULFONAMIDES; TUMOR CELLS, CULTURED;

EID: 0033526914     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00276-0     Document Type: Article

References (12)

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2. 2. Shan, B.; Medina, J. C.; Santha, E.; Frankmoelle, W. P.; Chou, T. C.; Learned, R. M.; Narbut, M. R.; Scott, D.; Wu, P.; Jaen, J. C.; Rosen, T.; Timmermans, P. B. M. W. M.; Beckmann, H. Proc. Natl. Acad. Sci. U.S.A., 1999, 96, 5686.
3. 1H-NMR and mass spectrometry. Elemental analysis for all novel compounds was within 0.4% of the calculated values for C, H and N.
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