메뉴 건너뛰기




Volumn 35, Issue 12, 2011, Pages 1253-1259

Altered signal transduction in Folr1 -/- mouse embryo fibroblasts

Author keywords

Embryo; Folate; Transforming growth factor (tgf ); Wnt

Indexed keywords

AXIN; FOLATE RECEPTOR; FOLIC ACID; FOLIC ACID RECEPTOR 1; RNA 18S; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; WNT3A PROTEIN;

EID: 80955136520     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1042/CBI20110025     Document Type: Article
Times cited : (7)

References (41)
  • 1
    • 0023489254 scopus 로고
    • Identification of high affinity folate binding proteins in human erythrocyte membranes
    • Antony AC, Kincade RS, Verma RS, Krishnan SR. Identification of high affinity folate binding proteins in human erythrocyte membranes. J Clin Invest 1987;80:711-23.
    • (1987) J Clin Invest , vol.80 , pp. 711-723
    • Antony, A.C.1    Kincade, R.S.2    Verma, R.S.3    Krishnan, S.R.4
  • 3
    • 0025952140 scopus 로고
    • Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells Increased expression associated with a genomic rearrangement
    • Brigle KE, Westin EH, Houghton MT, Goldman ID. Characterization of two cDNAs encoding folate-binding proteins from L1210 murine leukemia cells. Increased expression associated with a genomic rearrangement. J Biol Chem 1991;266:17243-9.
    • (1991) Biol Chem , vol.266 , pp. 17243-17249
    • Brigle, K.E.1    Westin, E.H.2    Houghton, M.T.3    Goldman, I.D.4
  • 4
    • 0028008481 scopus 로고
    • Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells
    • Brigle KE, Spinella MJ, Westin EH, Goldman ID. Increased expression and characterization of two distinct folate binding proteins in murine erythroleukemia cells. Biochem Pharmacol 1994;47:337-45.
    • (1994) Biochem Pharmacol , vol.47 , pp. 337-345
    • Brigle, K.E.1    Spinella, M.J.2    Westin, E.H.3    Goldman, I.D.4
  • 5
    • 0032581370 scopus 로고    scopus 로고
    • Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family
    • Brown SD, Twells RC, Hey PJ, Cox RD, Levy ER, Soderman AR et al. Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family. Biochem Biophys Res Commun 1998;248:879-88.
    • (1998) Biochem Biophys Res Commun , vol.248 , pp. 879-888
    • Brown, S.D.1    Twells, R.C.2    Hey, P.J.3    Cox, R.D.4    Levy, E.R.5    Soderman, A.R.6
  • 6
  • 8
    • 0030966370 scopus 로고    scopus 로고
    • RFC-1 gene expression regulates folate absorption in mouse small intestine
    • Chiao JH, Roy K, Tolner B, Yang CH, Sirotnak FM. RFC-1 gene expression regulates folate absorption in mouse small intestine. J Biol Chem 1997;272:11165-70.
    • (1997) J Biol Chem , vol.272 , pp. 11165-11170
    • Chiao, J.H.1    Roy, K.2    Tolner, B.3    Yang, C.H.4    Sirotnak, F.M.5
  • 9
    • 84955821247 scopus 로고
    • Nomenclature and symbols for folic acid and related compounds
    • Cornish-Bowden A. Nomenclature and symbols for folic acid and related compounds. Pure Appl Chem 1986;59:833-6.
    • (1986) Pure Appl Chem , vol.59 , pp. 833-836
    • Cornish-Bowden, A.1
  • 10
    • 0037111431 scopus 로고    scopus 로고
    • Differential effects of arsenic on folate binding protein 2 (Folbp2) null and wild type fibroblasts
    • Crandall LZ, Vorce RL. Differential effects of arsenic on folate binding protein 2 (Folbp2) null and wild type fibroblasts. Toxicol Lett 2002;136:43-54.
    • (2002) Toxicol Lett , vol.136 , pp. 43-54
    • Crandall, L.Z.1    Vorce, R.L.2
  • 11
    • 41849147191 scopus 로고    scopus 로고
    • Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines
    • Crott JW, Liu Z, Keyes MK, Choi SW, Jang H, Moyer MP et al. Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling and folate uptake in human colonic epithelial cell lines. J Nutr Biochem 2008;19:328-35.
    • (2008) J Nutr Biochem , vol.19 , pp. 328-335
    • Crott, J.W.1    Liu, Z.2    Keyes, M.K.3    Choi, S.W.4    Jang, H.5    Moyer, M.P.6
  • 12
    • 0032934979 scopus 로고    scopus 로고
    • Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction
    • Datto MB, Frederick JP, Pan L, Borton AJ, Zhuang Y, Wang XF. Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction. Mol Cell Biol 1999;19:2495-504.
    • (1999) Mol Cell Biol , vol.19 , pp. 2495-2504
    • Datto, M.B.1    Frederick, J.P.2    Pan, L.3    Borton, A.J.4    Zhuang, Y.5    Wang, X.F.6
  • 13
    • 3342929525 scopus 로고    scopus 로고
    • Cellular localization and signaling activity of beta-catenin in migrating neural crest cells
    • de Melker AA, Desban N, Duband JL. Cellular localization and signaling activity of beta-catenin in migrating neural crest cells. Dev Dyn 2004;230:708-26.
    • (2004) Dev Dyn , vol.230 , pp. 708-726
    • de Melker, A.A.1    Desban, N.2    Duband, J.L.3
  • 14
    • 0024415796 scopus 로고
    • Molecular cloning and characterization of the human folatebinding protein cDNA from placenta and malignant tissue culture (KB) cells
    • Elwood PC. Molecular cloning and characterization of the human folatebinding protein cDNA from placenta and malignant tissue culture (KB) cells. J Biol Chem. 1989;264:14893-901.
    • (1989) J Biol Chem , vol.264 , pp. 14893-14901
    • Elwood, P.C.1
  • 15
    • 0036931633 scopus 로고    scopus 로고
    • Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure
    • Hamblet NS, Lijam N, Ruiz-Lozano P, Wang J, Yang Y, Luo Z et al. Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure. Development 2002;129:5827-38.
    • (2002) Development , vol.129 , pp. 5827-5838
    • Hamblet, N.S.1    Lijam, N.2    Ruiz-Lozano, P.3    Wang, J.4    Yang, Y.5    Luo, Z.6
  • 16
    • 64249159802 scopus 로고    scopus 로고
    • Folbp1 promotes embryonic myocardial cell proliferation and apoptosis through the WNT signal transduction pathway
    • Han SP, Pan Y, Peng YZ, Gu XQ, Chen RH, Guo XR. Folbp1 promotes embryonic myocardial cell proliferation and apoptosis through the WNT signal transduction pathway. Int J Mol Med 2009;23:321-30.
    • (2009) Int J Mol Med , vol.23 , pp. 321-330
    • Han, S.P.1    Pan, Y.2    Peng, Y.Z.3    Gu, X.Q.4    Chen, R.H.5    Guo, X.R.6
  • 17
    • 0031591946 scopus 로고    scopus 로고
    • Wnt signalling required for expansion of neural crest and CNS progenitors
    • Ikeya M, Lee SM, Johnson JE, McMahon AP, Takada S. Wnt signalling required for expansion of neural crest and CNS progenitors. Nature 1997;389:966-70.
    • (1997) Nature , vol.389 , pp. 966-970
    • Ikeya, M.1    Lee, S.M.2    Johnson, J.E.3    McMahon, A.P.4    Takada, S.5
  • 18
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/betacatenin/ Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • Jho EH, Zhang T, Domon C, Joo CK, Freund JN, Costantini F. Wnt/betacatenin/ Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol Cell Biol 2002;22:1172-83.
    • (2002) Mol Cell Biol , vol.22 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3    Joo, C.K.4    Freund, J.N.5    Costantini, F.6
  • 19
    • 21244489290 scopus 로고    scopus 로고
    • Gene expression profiling demonstrates that TGF-beta1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-beta signaling
    • Karlsson G, Liu Y, Larsson J, Goumans MJ, Lee JS, Thorgeirsson SS et al. Gene expression profiling demonstrates that TGF-beta1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-beta signaling. Physiol Genomics 2005;21:396-403.
    • (2005) Physiol Genomics , vol.21 , pp. 396-403
    • Karlsson, G.1    Liu, Y.2    Larsson, J.3    Goumans, M.J.4    Lee, J.S.5    Thorgeirsson, S.S.6
  • 20
    • 70149107491 scopus 로고    scopus 로고
    • A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling
    • Klinghoffer RA, Frazier J, Annis J, Berndt JD, Roberts BS, Arthur WT et al. A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling. PLoS ONE 2009;4:e6892.
    • (2009) LoS ONE , vol.4
    • Klinghoffer, R.A.1    Frazier, J.2    Annis, J.3    Berndt, J.D.4    Roberts, B.S.5    Arthur, W.T.6
  • 21
    • 0028912452 scopus 로고
    • Role of the transforming growth factor-beta family in the expression of cranial neural crest-specific phenotypes
    • Leblanc GG, Holbert TE, Darland T. Role of the transforming growth factor-beta family in the expression of cranial neural crest-specific phenotypes. J Neurobiol 1995;26:497-510.
    • (1995) J Neurobiol , vol.26 , pp. 497-510
    • Leblanc, G.G.1    Holbert, T.E.2    Darland, T.3
  • 22
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992;69:915-26.
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 23
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 22DDCt method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 22DDCt method. Methods 2001;25:402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 24
    • 0041305877 scopus 로고    scopus 로고
    • Membrane transport of folates
    • Matherly LH, Goldman DI. Membrane transport of folates. Vitam Horm 2003;66:403-56.
    • (2003) Vitam Horm , vol.66 , pp. 403-456
    • Matherly, L.H.1    Goldman, D.I.2
  • 26
    • 33646187201 scopus 로고    scopus 로고
    • Effects of folate deficiency on gene expression in the apoptosis and cancer pathways in colon cancer cells
    • Novakovic P, Stempak JM, Sohn KJ, Kim YI. Effects of folate deficiency on gene expression in the apoptosis and cancer pathways in colon cancer cells. Carcinogenesis 2006;27:916-24.
    • (2006) Carcinogenesis , vol.27 , pp. 916-924
    • Novakovic, P.1    Stempak, J.M.2    Sohn, K.J.3    Kim, Y.I.4
  • 27
    • 0027417620 scopus 로고
    • Expression of the human placental folate receptor transcript is regulated in human tissues Organization and full nucleotide sequence of the gene
    • Page ST, Owen WC, Price K, Elwood PC. Expression of the human placental folate receptor transcript is regulated in human tissues. Organization and full nucleotide sequence of the gene. J Mol Biol 1993;229:1175-83.
    • (1993) J Mol Biol , vol.229 , pp. 1175-1183
    • Page, S.T.1    Owen, W.C.2    Price, K.3    Elwood, P.C.4
  • 28
    • 0032884078 scopus 로고    scopus 로고
    • Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development
    • Piedrahita JA, Oetama B, Bennett GD, van Waes J, Kamen BA, Richardson J et al. Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. Nat Genet 1999;23:228-32.
    • (1999) Nat Genet , vol.23 , pp. 228-232
    • Piedrahita, J.A.1    Oetama, B.2    Bennett, G.D.3    van Waes, J.4    Kamen, B.A.5    Richardson, J.6
  • 29
    • 33751244559 scopus 로고    scopus 로고
    • Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption
    • Qiu A, Jansen M, Sakaris A, Min SH, Chattopadhyay S, Tsai E et al. Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption. Cell 2006;127:917-28.
    • (2006) Cell , vol.127 , pp. 917-928
    • Qiu, A.1    Jansen, M.2    Sakaris, A.3    Min, S.H.4    Chattopadhyay, S.5    Tsai, E.6
  • 30
    • 28844508274 scopus 로고    scopus 로고
    • IGF-1 protein expression in rat embryo skull bone in folic acid-restricted diet
    • Santoso MI, Rohman MS. Decreased TGF-beta1 and IGF-1 protein expression in rat embryo skull bone in folic acid-restricted diet. J Nutr Biochem 2006;17:51-6.
    • (2006) J Nutr Biochem , vol.17 , pp. 51-56
    • Santoso, M.I.1    Rohman, M.S.2    Decreased Tgf-beta1, .3
  • 31
    • 0021143125 scopus 로고
    • Periconceptional vitamin supplementation and the prevention of neural tube defects in south-east England and Northern Ireland
    • Seller MJ, Nevin NC. Periconceptional vitamin supplementation and the prevention of neural tube defects in south-east England and Northern Ireland. J Med Genet 1984;21:325-30.
    • (1984) J Med Genet , vol.21 , pp. 325-330
    • Seller, M.J.1    Nevin, N.C.2
  • 32
    • 0028206803 scopus 로고
    • Identification of a novel folate receptor, a truncated receptor, and receptor type beta in hematopoietic cells: cDNA cloning, expression, immunoreactivity, and tissue specificity
    • Shen F, Ross JF, Wang X, Ratnam M. Identification of a novel folate receptor, a truncated receptor, and receptor type beta in hematopoietic cells: cDNA cloning, expression, immunoreactivity, and tissue specificity. Biochemistry 1994;33:1209-15.
    • (1994) Biochemistry , vol.33 , pp. 1209-1215
    • Shen, F.1    Ross, J.F.2    Wang, X.3    Ratnam, M.4
  • 33
    • 34247100722 scopus 로고    scopus 로고
    • Antifolate pseudo-resistance due to elevated levels of thymidine and hypoxanthine in a commercial serum preparation
    • Simon M, Blatter J, Granzow C. Antifolate pseudo-resistance due to elevated levels of thymidine and hypoxanthine in a commercial serum preparation. Anticancer Res. 2007;27:769-73.
    • (2007) Anticancer Res , vol.27 , pp. 769-773
    • Simon, M.1    Blatter, J.2    Granzow, C.3
  • 34
    • 0022353539 scopus 로고
    • Obligate genetic expression in tumor cells of a fetal membrane property mediating 'folate' transport: biological significance and implications for improved therapy of human cancer
    • Sirotnak FM. Obligate genetic expression in tumor cells of a fetal membrane property mediating 'folate' transport: biological significance and implications for improved therapy of human cancer. Cancer Res 1985;45:3992-4000.
    • (1985) Cancer Res , vol.45 , pp. 3992-4000
    • Sirotnak, F.M.1
  • 36
    • 0034722715 scopus 로고    scopus 로고
    • Identification of two putative novel folate receptor genes in humans and mouse
    • Spiegelstein O, Eudy JD, Finnell RH. Identification of two putative novel folate receptor genes in humans and mouse. Gene 2000;258:117-25.
    • (2000) Gene , vol.258 , pp. 117-125
    • Spiegelstein, O.1    Eudy, J.D.2    Finnell, R.H.3
  • 39
    • 0242721599 scopus 로고    scopus 로고
    • Cell-type-specific activation of PAK2 by transforming growth factor beta independent of Smad2 and Smad3
    • Wilkes MC, Murphy SJ, Garamszegi N, Leof EB. Cell-type-specific activation of PAK2 by transforming growth factor beta independent of Smad2 and Smad3. Mol Cell Biol 2003;23:8878-89.
    • (2003) Mol Cell Biol , vol.23 , pp. 8878-8889
    • Wilkes, M.C.1    Murphy, S.J.2    Garamszegi, N.3    Leof, E.B.4
  • 40
    • 0037099745 scopus 로고    scopus 로고
    • TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses
    • Yu L, Hebert MC, Zhang YE. TGF-beta receptor-activated p38 MAP kinase mediates Smad-independent TGF-beta responses. EMBO J 2002;21:3749-59.
    • (2002) EMBO J , vol.21 , pp. 3749-3759
    • Yu, L.1    Hebert, M.C.2    Zhang, Y.E.3
  • 41
    • 0035971190 scopus 로고    scopus 로고
    • Rescue of embryonic lethality in reduced folate carrier-deficient mice by maternal folic acid supplementation reveals early neonatal failure of hematopoietic organs
    • Zhao R, Russell RG, Wang Y, Liu L, Gao F, Kneitz B et al. Rescue of embryonic lethality in reduced folate carrier-deficient mice by maternal folic acid supplementation reveals early neonatal failure of hematopoietic organs. J Biol Chem 2001;276:10224-8.
    • (2001) J Biol Chem , vol.276 , pp. 10224-10228
    • Zhao, R.1    Russell, R.G.2    Wang, Y.3    Liu, L.4    Gao, F.5    Kneitz, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.