메뉴 건너뛰기




Volumn 27, Issue 2, 2007, Pages 769-773

Antifolate pseudo-resistance due to elevated levels of thymidine and hypoxanthine in a commercial serum preparation

Author keywords

Antifolate resistance; Antifolate salvage; CCRF CEM cells; FBS Gold; FCS Gold; Fetal bovine serum; KB cells

Indexed keywords

HYPOXANTHINE; METHOTREXATE; PEMETREXED; THYMIDINE;

EID: 34247100722     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (14)
  • 3
    • 0030902661 scopus 로고    scopus 로고
    • Resistance to chemotherapeutic antimetabolites: A function of salvage pathway involvement and cellular response to DNA damage
    • Kinsella AR, Smith D and Pickard M: Resistance to chemotherapeutic antimetabolites: a function of salvage pathway involvement and cellular response to DNA damage. Br J Cancer 75: 935-945, 1997.
    • (1997) Br J Cancer , vol.75 , pp. 935-945
    • Kinsella, A.R.1    Smith, D.2    Pickard, M.3
  • 4
    • 0022643338 scopus 로고
    • Endogenous thymidine and hypoxanthine are a source of error in evaluating methotrexate cytotoxicity by clonogenic assays using undialyzed fetal bovine serum
    • Sobrero AF and Bertino JR: Endogenous thymidine and hypoxanthine are a source of error in evaluating methotrexate cytotoxicity by clonogenic assays using undialyzed fetal bovine serum. Int J Cell Cloning 4: 51-62, 1986.
    • (1986) Int J Cell Cloning , vol.4 , pp. 51-62
    • Sobrero, A.F.1    Bertino, J.R.2
  • 5
    • 11844252002 scopus 로고    scopus 로고
    • Low tumor cell density environment yields survival advantage of tumor cells exposed to MTX in vitro
    • de Anta JM, Real FX and Mayol X: Low tumor cell density environment yields survival advantage of tumor cells exposed to MTX in vitro. Biochim Biophys Acta 1721: 98-106, 2005.
    • (2005) Biochim Biophys Acta , vol.1721 , pp. 98-106
    • de Anta, J.M.1    Real, F.X.2    Mayol, X.3
  • 6
    • 18944403577 scopus 로고    scopus 로고
    • Cytotoxicity determination without photochemical artifacts
    • Heuser M, Kopun M, Rittgen W and Granzow C: Cytotoxicity determination without photochemical artifacts. Cancer Lett 223: 57-66, 2005.
    • (2005) Cancer Lett , vol.223 , pp. 57-66
    • Heuser, M.1    Kopun, M.2    Rittgen, W.3    Granzow, C.4
  • 9
    • 0018823572 scopus 로고
    • Methods for growth of cultured cells in serum-free medium
    • Barnes D and Sato G: Methods for growth of cultured cells in serum-free medium. Anal Biochem 102: 255-270, 1980.
    • (1980) Anal Biochem , vol.102 , pp. 255-270
    • Barnes, D.1    Sato, G.2
  • 11
    • 0026494947 scopus 로고
    • A dideazatetrahydrofolate analogue lacking a chiral center at C-6, N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl] benzoyl]-L-glutamic acid, is an inhibitor of thymidylate synthase
    • Taylor EC, Kuhnt D, Shih C, Rinzel SM, Grindey GB, Barredo J, Jannatipour M and Moran RG: A dideazatetrahydrofolate analogue lacking a chiral center at C-6, N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl] benzoyl]-L-glutamic acid, is an inhibitor of thymidylate synthase. J Med Chem 35: 4450-4454, 1992.
    • (1992) J Med Chem , vol.35 , pp. 4450-4454
    • Taylor, E.C.1    Kuhnt, D.2    Shih, C.3    Rinzel, S.M.4    Grindey, G.B.5    Barredo, J.6    Jannatipour, M.7    Moran, R.G.8
  • 12
    • 0032914341 scopus 로고    scopus 로고
    • Biological activity of the multitargeted antifolate, MTA (LY231514), in human cell lines with different resistance mechanisms to antifolate drugs
    • Schultz RM, Chen VJ, Bewley JR, Roberts EF, Shih C and Dempsey JA: Biological activity of the multitargeted antifolate, MTA (LY231514), in human cell lines with different resistance mechanisms to antifolate drugs. Semin Oncol 26: 68-73, 1999.
    • (1999) Semin Oncol , vol.26 , pp. 68-73
    • Schultz, R.M.1    Chen, V.J.2    Bewley, J.R.3    Roberts, E.F.4    Shih, C.5    Dempsey, J.A.6
  • 13
    • 0026062272 scopus 로고
    • Novel pyrrolo[2,3-d]pyrimidine antifolates: Synthesis and antitumor activities
    • Miwa T, Hitaka T, Akimoto H and Nomura H: Novel pyrrolo[2,3-d]pyrimidine antifolates: synthesis and antitumor activities. J Med Chem 34: 555-560, 1991.
    • (1991) J Med Chem , vol.34 , pp. 555-560
    • Miwa, T.1    Hitaka, T.2    Akimoto, H.3    Nomura, H.4
  • 14
    • 0035821589 scopus 로고    scopus 로고
    • Synthesis, antifolate, and antitumor activities of classical and nonclassical 2-amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines
    • Gangjee A, Vidwans A, Elzein E, McGuire JJ, Queener SF and Kisliuk RL: Synthesis, antifolate, and antitumor activities of classical and nonclassical 2-amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines. J Med Chem 44: 1993-2003, 2001.
    • (2001) J Med Chem , vol.44 , pp. 1993-2003
    • Gangjee, A.1    Vidwans, A.2    Elzein, E.3    McGuire, J.J.4    Queener, S.F.5    Kisliuk, R.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.