Rescue of Embryonic Lethality in Reduced Folate Carrier-deficient Mice by Maternal Folic Acid Supplementation Reveals Early Neonatal Failure of Hematopoietic Organs

Journal of Biological Chemistry

Volumn 276, Issue 13, 2001, Pages 10224-10228

  Zhao, Rongbao ^a   Russell, Robert G ^a   Wang, Yanhua ^a   Liu, Laibin ^a   Gao, Feng ^a   Kneitz, Burkhard ^a   Edelmann, Winfried ^a   Goldman, I David ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; BLOOD; CELLS; ORGANIC ACIDS;

EMBRYONIC LETHALITY;

BIOCHEMISTRY;

5 METHYLTETRAHYDROFOLIC ACID; FOLIC ACID; REDUCED FOLATE CARRIER; REDUCED FOLATE CARRIER 1; UNCLASSIFIED DRUG; 5-METHYLTETRAHYDROFOLATE; CARRIER PROTEIN; ENZYME INHIBITOR; MEMBRANE PROTEIN; METHOTREXATE; SLC19A2 PROTEIN, MOUSE; TETRAHYDROFOLIC ACID DERIVATIVE;

ANIMAL CELL; ARTICLE; BONE MARROW; CONTROLLED STUDY; DIET SUPPLEMENTATION; EMBRYO; EMBRYO DEATH; ERYTHROPOIESIS; FOLIC ACID BLOOD LEVEL; HEMATOPOIETIC SYSTEM; KIDNEY DEVELOPMENT; LIVER; MAMMAL CELL; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SEMINIFEROUS TUBULE; SPLEEN; THYMUS; ALLELE; ANIMAL; C57BL MOUSE; CROSS BREEDING; CYTOLOGY; FETUS DEATH; GENE VECTOR; GENETIC RECOMBINATION; GENETICS; GENOTYPE; HEMATOPOIESIS; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT; STEM CELL; TIME; WESTERN BLOTTING;

ANIMALIA; MAMMALIA;

ALLELES; ANIMALS; BLOTTING, WESTERN; BONE MARROW; CARRIER PROTEINS; CROSSES, GENETIC; DIETARY SUPPLEMENTS; ENZYME INHIBITORS; FETAL DEATH; FOLIC ACID; GENETIC VECTORS; GENOTYPE; HEMATOPOIESIS; LIVER; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; METHOTREXATE; MICE; MICE, INBRED C57BL; RECOMBINATION, GENETIC; SPLEEN; STEM CELLS; TETRAHYDROFOLATES; THYMUS GLAND; TIME FACTORS;

EID: 0035971190     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C000905200     Document Type: Article

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