Nitazoxanide disrupts membrane potential and intrabacterial pH homeostasis of Mycobacterium tuberculosis

ACS Medicinal Chemistry Letters

Volumn 2, Issue 11, 2011, Pages 849-854

  De Carvalho, Luiz Pedro S ^a,b   Darby, Crystal M ^a   Rhee, Kyu Y ^a   Nathan, Carl ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

membrane potential; metabolomics; Mycobacterium tuberculosis; niclosamide; Nitazoxanide; pH homeostasis; tizoxanide

Indexed keywords

NICLOSAMIDE; NITAZOXANIDE; REACTIVE NITROGEN SPECIES; TIZOXANIDE;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; DEACETYLATION; DRUG MECHANISM; HOMEOSTASIS; MEMBRANE POTENTIAL; METABOLOMICS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PH; PRIORITY JOURNAL;

MYCOBACTERIUM TUBERCULOSIS;

EID: 80955132757     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml200157f     Document Type: Article

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