Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein

Structure

Volumn 19, Issue 11, 2011, Pages 1644-1654

  Samygina, Valeria R ^a   Popov, Alexander N ^b   Cabo Bilbao, Aintzane ^a   Ochoa Lizarralde, Borja ^a   Goni De Cerio, Felipe ^a   Zhai, Xiuhong ^c   Molotkovsky, Julian G ^d   Patel, Dinshaw J ^e   Brown, Rhoderick E ^c   Malinina, Lucy ^a  

^a CIC BIOGUNE   (Spain)

^b EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^c UNIVERSITY OF MINNESOTA   (United States)

^d SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 O SULFO GALACTOSYLCERAMIDE; CELL PROTEIN; GALACTOSYLCERAMIDE; GLYCOLIPID TRANSFER PROTEIN; N NERVONOYLSULFATIDE; N OLEOYLGLUCOSYLCERAMIDE; PHENYLALANINE DERIVATIVE; SPHINGOSINE; SULFATIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN STRUCTURE; WILD TYPE;

AMINO ACID SUBSTITUTION; BINDING SITES; CARRIER PROTEINS; CRYSTALLOGRAPHY, X-RAY; HUMANS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN MULTIMERIZATION; SUBSTRATE SPECIFICITY; SULFOGLYCOSPHINGOLIPIDS; SURFACE PROPERTIES;

EID: 80855133528     PISSN: 09692126     EISSN: 18784186     Source Type: Journal    
DOI: 10.1016/j.str.2011.09.011     Document Type: Article

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