The correlation of in vivo burn scar contraction with the level of α-smooth muscle actin expression

Burns

Volumn 37, Issue 8, 2011, Pages 1367-1377

  Wang, Xue Qing ^a   Kravchuk, Olena ^a   Winterford, Clay ^a   Kimble, Roy M ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Alpha smooth muscle actin; Burns; Myofibroblasts; Scar contraction

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BURN DRESSING; BURN SCAR; CONTROLLED STUDY; CORRELATIONAL STUDY; EPITHELIZATION; HYPERTROPHIC SCAR; IN VIVO STUDY; NONHUMAN; PROTEIN EXPRESSION; SKIN BIOPSY; STATISTICAL ANALYSIS; SWINE; WOUND CLOSURE; WOUND CONTRACTION; WOUND HEALING;

ACTINS; ANIMALS; BURNS; CICATRIX, HYPERTROPHIC; CONTRACTURE; IMMUNOHISTOCHEMISTRY; MODELS, ANIMAL; SWINE;

EID: 80855123782     PISSN: 03054179     EISSN: 18791409     Source Type: Journal    
DOI: 10.1016/j.burns.2011.07.018     Document Type: Article

References (45)

1. Greenhalgh DG Wound healing D.N. Herndon, Total burn care 2007 W.B. Saunders London 578 595
2. H.K. Hawkins, and Pereira CT Pathophysiology of the burn scar D.N. Herndon, Total burn scar 2007 W.B. Saunders London 608 619
3. P.G. Scott, A. Ghahary, J. Wang, and E.E. Tredget Molecular and cellular basis of hypertrophic scarring D.N. Herndon, Total burn care 2007 W.B. Saunders London 596 607
4. A. Desmouliere, C. Chaponnier, and G. Gabbiani Tissue repair, contraction, and the myofibroblast Wound Repair Regen 13 2005 7 12 (Pubitemid 40250424)
5. G. Gabbiani The myofibroblast in wound healing and fibrocontractive diseases J Pathol 200 2003 500 503 (Pubitemid 36818250)
6. G. Gabbiani, G.B. Ryan, and G. Majne Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction Experientia 27 1971 549 550
7. G. Majno, G. Gabbiani, B.J. Hirschel, G.B. Ryan, and P.R. Statkov Contraction of granulation tissue in vitro: similarity to smooth muscle Science 173 1971 548 550
8. J.J. Tomasek, G. Gabbiani, B. Hinz, C. Chaponnier, and R.A. Brown Myofibroblasts and mechano-regulation of connective tissue remodelling Nat Rev Mol Cell Biol 3 2002 349 363 (Pubitemid 34619269)
9. B. Hinz Formation and function of the myofibroblast during tissue repair J Invest Dermatol 127 2007 526 537
10. A.M. Costa, S. Peyrol, L.C. Porto, J.P. Comparin, J.L. Foyatier, and A. Desmouliere Mechanical forces induce scar remodeling. Study in non-pressure-treated versus pressure-treated hypertrophic scars Am J Pathol 155 1999 1671 1679
11. H.P. Ehrlich, A. Desmouliere, R.F. Diegelmann, I.K. Cohen, C.C. Compton, and W.L. Garner Morphological and immunochemical differences between keloid and hypertrophic scar Am J Pathol 145 1994 105 113 (Pubitemid 24217489)
12. N.V. Kamath, A. Ormsby, W.F. Bergfeld, and N.S. House A light microscopic and immunohistochemical evaluation of scars J Cutan Pathol 29 2002 27 32 (Pubitemid 34155165)
13. J.Y. Lee, C.C. Yang, S.C. Chao, and T.W. Wong Histopathological differential diagnosis of keloid and hypertrophic scar Am J Dermatopathol 26 2004 379 384 (Pubitemid 39287358)
14. Y. Liu, Y. Cen, T. Ying, and X. Xu The role of myofibroblast in the development of pathological scar Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 19 2005 39 41
15. Y. Tian, S. Tang, and S. Luo A study on the expressions and the correlation of TGF-beta and alpha-SMA in scars Zhonghua Zheng Xing Wai Ke Za Zhi 16 2000 75 77
16. B. Nedelec, H. Shankowsky, P.G. Scott, A. Ghahary, and E.E. Tredget Myofibroblasts and apoptosis in human hypertrophic scars: the effect of interferon-alpha2b Surgery 130 2001 798 808 (Pubitemid 33022386)
17. R.J. Eddy, J.A. Petro, and J.J. Tomasek Evidence for the nonmuscle nature of the "myofibroblast" of granulation tissue and hypertropic scar. An immunofluorescence study Am J Pathol 130 1988 252 260 (Pubitemid 18076359)
18. I. Darby, O. Skalli, and G. Gabbiani Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing Lab Invest 63 1990 21 29 (Pubitemid 20234670)
19. M.P. Welch, G.F. Odland, and R.A. Clark Temporal relationships of F-actin bundle formation, collagen and fibronectin matrix assembly, and fibronectin receptor expression to wound contraction J Cell Biol 110 1990 133 145
20. D.L. Cass, K.G. Sylvester, E.Y. Yang, T.M. Crombleholme, and N.S. Adzick Myofibroblast persistence in fetal sheep wounds is associated with scar formation J Pediatr Surg 32 1997 1017 1021 discussion 1021-1012
21. J.F. Fraser, L. Cuttle, M. Kempf, G.E. Phillips, P.K. O'Rourke, and K. Choo Deep dermal burn injury results in scarless wound healing in the ovine fetus Wound Repair Regen 13 2005 189 197 (Pubitemid 40489869)
22. A. Mawaki, T. Nakatani, J. Sugama, and C. Konya Relationship between the distribution of myofibroblasts, and stellar and circular scar formation due to the contraction of square and circular wound healing Anat Sci Int 82 2007 147 155 (Pubitemid 47103665)
23. M.M. Ulrich, M. Verkerk, L. Reijnen, M. Vlig, A.J. van den Bogaerdt, and E. Middelkoop Expression profile of proteins involved in scar formation in the healing process of full-thickness excisional wounds in the porcine model Wound Repair Regen 15 2007 482 490 (Pubitemid 47087640)
24. D.H. Adams, N. Ruzehaji, X.L. Strudwick, J.E. Greenwood, H.D. Campbell, and R. Arkell Attenuation of Flightless I, an actin-remodelling protein, improves burn injury repair via modulation of transforming growth factor (TGF)-beta1 and TGF-beta3 Br J Dermatol 161 2009 326 336
25. Y. Akasaka, I. Ono, A. Tominaga, Y. Ishikawa, K. Ito, and T. Suzuki Basic fibroblast growth factor in an artificial dermis promotes apoptosis and inhibits expression of alpha-smooth muscle actin, leading to reduction of wound contraction Wound Repair Regen 15 2007 378 389 (Pubitemid 46817414)
26. B. Hinz, G. Gabbiani, and C. Chaponnier The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo J Cell Biol 157 2002 657 663 (Pubitemid 34839793)
27. B. Hinz, D. Mastrangelo, C.E. Iselin, C. Chaponnier, and G. Gabbiani Mechanical tension controls granulation tissue contractile activity and myofibroblast differentiation Am J Pathol 159 2001 1009 1020 (Pubitemid 32847191)
28. X.Q. Wang, O. Kravchuk, P.Y. Liu, M. Kempf, C.V. Boogaard, and P. Lau The evaluation of a clinical scar scale for porcine burn scars Burns 35 2009 538 546
29. X.Q. Wang, P.Y. Liu, M. Kempf, L. Cuttle, A.H. Chang, and M. Wong Burn healing is dependent on burn site: a quantitative analysis from a porcine burn model Burns 35 2009 264 269
30. X.Q. Wang, M. Kempf, P.Y. Liu, L. Cuttle, H.E. Chang, and O. Kravchuk Conservative surgical debridement as a burn treatment: supporting evidence from a porcine burn model Wound Repair Regen 16 2008 774 783
31. M. Kempf, L. Cuttle, P.Y. Liu, X.Q. Wang, and R.M. Kimble Important improvements to porcine skin burn models, in search of the perfect burn Burns 35 2009 454 455
32. X.Q. Wang, M. Kempf, J. Mott, H.E. Chang, R. Francis, and P.Y. Liu Silver absorption on burns after the application of acticoat: data from pediatric patients and a porcine burn model J Burn Care Res 30 2009 341 348
33. X.Q. Wang, O. Kravchuk, and R.M. Kimble A retrospective review of burn dressings on a porcine burn model Burns 36 2010 680 687
34. A. Leask, A. Holmes, and D.J. Abraham Connective tissue growth factor: a new and important player in the pathogenesis of fibrosis Curr Rheumatol Rep 4 2002 136 142
35. P. Shephard, G. Martin, S. Smola-Hess, G. Brunner, T. Krieg, and H. Smola Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1 Am J Pathol 164 2004 2055 2066 (Pubitemid 38669353)
36. K. Higashi, Y. Inagaki, K. Fujimori, A. Nakao, H. Kaneko, and I. Nakatsuka Interferon-gamma interferes with transforming growth factor-beta signaling through direct interaction of YB-1 with Smad3 J Biol Chem 278 2003 43470 43479 (Pubitemid 37345970)
37. R.M. Gallucci, E.G. Lee, and J.J. Tomasek IL-6 modulates alpha-smooth muscle actin expression in dermal fibroblasts from IL-6-deficient mice J Invest Dermatol 126 2006 561 568 (Pubitemid 43255642)
38. A. Micera, E. Vigneti, D. Pickholtz, R. Reich, O. Pappo, and S. Bonini Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for this factor in tissue repair Proc Natl Acad Sci USA 98 2001 6162 6167 (Pubitemid 32488210)
39. T. Liu, S.M. Dhanasekaran, H. Jin, B. Hu, S.A. Tomlins, and A.M. Chinnaiyan FIZZ1 stimulation of myofibroblast differentiation Am J Pathol 164 2004 1315 1326 (Pubitemid 38387797)
40. X.Q. Wang, H.E. Chang, R. Francis, H. Olszowy, P.Y. Liu, and M. Kempf Silver deposits in cutaneous burn scar tissue is a common phenomenon following application of a silver dressing J Cutan Pathol 36 2009 788 792
41. E.A. Deitch, T.M. Wheelahan, M.P. Rose, J. Clothier, and J. Cotter Hypertrophic burn scars: analysis of variables J Trauma 23 1983 895 898 (Pubitemid 13022400)
42. E.N. Gangemi, D. Gregori, P. Berchialla, E. Zingarelli, M. Cairo, and D. Bollero Epidemiology and risk factors for pathologic scarring after burn wounds Arch Facial Plast Surg 10 2008 93 102
43. W.S. McDonald, and E.A. Deitch Hypertrophic skin grafts in burned patients: a prospective analysis of variables J Trauma 27 1987 147 150 (Pubitemid 17055747)
44. T.C. Cubison, S.A. Pape, and N. Parkhouse Evidence for the link between healing time and the development of hypertrophic scars (HTS) in paediatric burns due to scald injury Burns 32 2006 992 999 (Pubitemid 44647539)
45. X.Q. Wang, G.E. Phillips, I. Wilkie, R. Greer, and R.M. Kimble Microscopic inflammatory foci in burn scars: data from a porcine burn model J Cutan Pathol 37 2010 530 534