S-Glucuronidation of 7-mercapto-4-methylcoumarin by human UDP glycosyltransferases in genetically engineered fission yeast cells

Biological Chemistry

Volumn 392, Issue 12, 2011, Pages 1089-1095

  Buchheit, Daniela ^a   Schmitt, Ellen I ^a   Bischoff, Daniel ^b   Ebner, Thomas ^b   Bureik, Matthias ^a  

^a PomBioTech GmbH   (Germany)

^b BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

Coumarin; Fission yeast; S glucuronide; Thiol; UGT; Whole cell biotransformation

Indexed keywords

7 MERCAPTO 4 METHYLCOUMARIN; COUMARIN; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; HYMECROMONE; ISOTOPE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCOSE DEHYDROGENASE;

ARTICLE; ATOM; BIOTRANSFORMATION; CATALYSIS; CONJUGATION; CONTROLLED STUDY; ENZYME SPECIFICITY; GENETIC ENGINEERING; GLUCURONIDATION; HUMAN; HUMAN CELL; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; SCHIZOSACCHAROMYCES POMBE; YEAST CELL;

COUMARINS; GENETIC ENGINEERING; GLUCURONIDES; GLYCOSYLTRANSFERASES; HUMANS; MICROSOMES, LIVER; SCHIZOSACCHAROMYCES;

SCHIZOSACCHAROMYCETACEAE;

EID: 80755171230     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2011.194     Document Type: Article

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