NMR Characterization of an S-linked glucuronide metabolite of the potent, novel, nonsteroidal progesterone agonist tanaproget

Drug Metabolism and Disposition

Volumn 34, Issue 8, 2006, Pages 1283-1287

  Keating, Kelly A ^a,b   McConnell, Oliver ^a   Zhang, Yingru ^a   Shen, Li ^a   DeMaio, William ^a   Mallis, Larry ^a   Elmarakby, Sayed ^a   Chandrasekaran, Appavu ^a  

^a PFIZER INC   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOXAZINE 2 THIONE; DRUG METABOLITE; GLUCURONIDE; NITROGEN; PROGESTERONE RECEPTOR AGONIST; SULFUR; TANAPROGET; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; TANDEM MASS SPECTROMETRY;

ANIMALS; BENZOXAZINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCURONIDES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICROSOMES, LIVER; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PROGESTERONE; THIONES;

EID: 33746078888     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.105.008763     Document Type: Article

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