Production of ibuprofen acyl glucosides by human UGT2B7

Drug Metabolism and Disposition

Volumn 39, Issue 12, 2011, Pages 2174-2181

  Buchheit, Daniela ^a   Drǎgan, Cǎlin Aurel ^a   Schmitt, Ellen I ^a   Bureik, Matthias ^a  

^a PomBioTech GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLGLUCOSIDE DERIVATIVE; CARBON 13; DRUG METABOLITE; GLUCOSE; GLUCURONOSYLTRANSFERASE 2B7; IBUPROFEN; RECOMBINANT ENZYME; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE GLUCOSE; URIDINE TRIPHOSPHATE GLUCOSE 1 PHOSPHATE URIDYLYLTRANSFERASE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG TRANSFORMATION; FUNGAL CELL; FUNGAL GENE; FYU1 GENE; GENE OVEREXPRESSION; GLUCONEOGENESIS; HUMAN; HUMAN CELL; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN VARIANT; SCHIZOSACCHAROMYCES POMBE; SPCC1322.04 GENE; SPCC794.10 GENE;

BASE SEQUENCE; BIOMASS; CHROMATOGRAPHY, LIQUID; DNA PRIMERS; GLUCOSIDES; GLUCURONOSYLTRANSFERASE; HUMANS; IBUPROFEN; MASS SPECTROMETRY; RECOMBINANT PROTEINS; SCHIZOSACCHAROMYCES;

SCHIZOSACCHAROMYCES POMBE; SCHIZOSACCHAROMYCETACEAE;

EID: 80755185937     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.111.041640     Document Type: Article

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