Interferon-signaling pathway: Associations with colon and rectal cancer risk and subsequent survival

Carcinogenesis

Volumn 32, Issue 11, 2011, Pages 1660-1667

  Slattery, Martha L ^a   Lundgreen, Abbie ^a   Bondurant, Kristina L ^b   Wolff, Roger K ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^b UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON; INTERLEUKIN 6; NONSTEROID ANTIINFLAMMATORY AGENT;

ADULT; AGED; ARTICLE; CANCER INCIDENCE; CANCER RISK; CANCER SURVIVAL; COLON CANCER; CONTROLLED STUDY; GENE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; IFNG GENE; IFNGR1 GENE; IFNGR2 GENE; IRF GENE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RECTUM CANCER; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; CASE-CONTROL STUDIES; COLONIC NEOPLASMS; FEMALE; HUMANS; INCIDENCE; INTERFERON REGULATORY FACTORS; INTERFERONS; INTERLEUKIN-6; MALE; MIDDLE AGED; NF-KAPPA B; POLYMORPHISM, SINGLE NUCLEOTIDE; PROGNOSIS; RECTAL NEOPLASMS; RISK FACTORS; SIGNAL TRANSDUCTION; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 80755168367     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr189     Document Type: Article

References (35)

1. Gough,D.J. et al. (2008) IFNgamma signaling-does it mean JAK-STAT? Cytokine Growth Factor Rev., 19, 383-394.
2. Harada,H. et al. (1998) The role of interferon regulatory factors in the interferon system and cell growth control. Biochimie, 80, 641-650.
3. Saha,B. et al. (2010) Gene modulation and immunoregulatory roles of interferon gamma. Cytokine, 50, 1-14.
4. Platanias,L.C. et al. (1999) Signaling pathways activated by interferons. Exp. Hematol., 27, 1583-1592.
5. Bach,E.A. et al. (1997) The IFN gamma receptor: a paradigm for cytokine receptor signaling. Annu. Rev. Immunol., 15, 563-591.
6. Taniguchi,T. et al. (2001) IRF family of transcription factors as regulators of host defense. Annu. Rev. Immunol., 19, 623-655.
7. Schuhmann,D. et al. (2011) Interfering with interferon-gamma signalling in intestinal epithelial cells: selective inhibition of apoptosis-maintained secretion of anti-inflammatory interleukin-18 binding protein. Clin. Exp. Immunol., 163, 65-76.
8. Talseth,B.A. et al. (2007) Lack of association between genetic polymorphisms in cytokine genes and disease expression in patients with hereditary non-polyposis colorectal cancer. Scand. J. Gastroenterol., 42, 628-632.
9. Lee,Y.S. et al. (2010) Association between interleukin-4R and TGF-beta1 gene polymorphisms and the risk of colorectal cancer in a Korean population. Colorectal Dis., 12, 1208-1212.
10. Curtin,K. et al. (2010) Exploring multilocus associations of inflammation genes and colorectal cancer risk using hapConstructor. BMC Med. Genet., 10, 170-181.
11. Slattery,M.L. et al. (1997) Energy balance and colon cancer-beyond physical activity. Cancer Res., 57, 75-80.
12. Slattery,M.L. et al. (2003) Physical activity and colorectal cancer. Am. J. Epidemiol., 158, 214-224.
13. Edwards,S. et al. (1994) Objective system for interviewer performance evaluation for use in epidemiologic studies. Am. J. Epidemiol., 140, 1020-1028.
14. Samowitz,W.S. et al. (2002) Prognostic significance of p53 mutations in colon cancer at the population level. Int. J. Cancer, 99, 597-602.
15. Slattery,M.L. et al. (2000) Associations between cigarette smoking, lifestyle factors, and microsatellite instability in colon tumors. J. Natl Cancer Inst., 92, 1831-1836.
16. Samowitz,W.S. et al. (2000) Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study. Cancer Epidemiol. Biomarkers Prev., 9, 1193-1197.
17. Slattery,M.L. et al. (2007) Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer. Int. J. Cancer, 120, 656-663.
18. Conneely,K.N. et al. (2007) So many correlated tests, so little time! rapid adjustment of P values for multiple correlated tests. Am. J. Hum. Genet., 81, 1158-1168.
19. Slattery,M.L. et al. (2007) IL6 genotypes and colon and rectal cancer. Cancer Causes Control, 18, 1095-1105.
20. Slattery,M.L. et al. (2004) Dietary calcium, vitamin D, VDR genotypes and colorectal cancer. Int. J. Cancer, 111, 750-756.
21. Caan,B.J. et al. (1998) Body size and the risk of colon cancer in a large case-control study. Int. J. Obes. Relat. Metab. Disord., 22, 178-184.
22. Slattery,M.L. et al. (2011) Genetic variation in the TGF{beta}-signaling pathway and colon and rectal cancer risk. Cancer Epidemiol. Biomarkers Prev., 20, 57-69.
23. Slattery,M.L. et al. (2005) Energy balance, insulin-related genes and risk of colon and rectal cancer. Int. J. Cancer, 115, 148-154.
24. Slattery,M.L. et al. (2003) Energy balance and rectal cancer: an evaluation of energy intake, energy expenditure, and body mass index. Nutr. Cancer, 46, 166-171.
25. McGillicuddy,F.C. et al. (2009) Interferon gamma attenuates insulin signaling, lipid storage, and differentiation in human adipocytes via activation of the JAK/STAT pathway. J. Biol. Chem., 284, 31936-31944.
26. Ahnen,D.J. (1998) Colon cancer prevention by NSAIDs: what is the mechanism of action? Eur. J. Surg. Suppl., 582, 111-114.
27. Freedman,A.N. et al. (2009) Colorectal cancer risk prediction tool for white men and women without known susceptibility. J. Clin. Oncol., 27, 686-693.
28. Kune,G.A. (2000) Colorectal cancer chemoprevention: aspirin, other NSAID and COX-2 inhibitors. Aust. N. Z. J. Surg., 70, 452-455.
29. Sandler,R.S. (1996) Aspirin and other nonsteroidal anti-inflammatory agents in the prevention of colorectal cancer. Important Adv. Oncol., 123-137.
30. Kode,A. et al. (2006) Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine release in primary human airway epithelial cells and in a variety of transformed alveolar epithelial cells. Respir. Res., 7, 132.
31. Ratovitski,E.A. (2011) DeltaNp63alpha/IRF6 interplay activates NOS2 transcription and induces autophagy upon tobacco exposure. Arch. Biochem. Biophys., 506, 208-215.
32. Hussain,S.P. et al. (2007) Inflammation and cancer: an ancient link with novel potentials. Int. J. Cancer, 121, 2373-2380.
33. Bouker,K.B. et al. (2005) Interferon regulatory factor-1 (IRF-1) exhibits tumor suppressor activities in breast cancer associated with caspase activation and induction of apoptosis. Carcinogenesis, 26, 1527-1535.
34. Tekautz,T.M. et al. (2006) Evaluation of IFN-gamma effects on apoptosis and gene expression in neuroblastoma-preclinical studies. Biochim. Biophys. Acta, 1763, 1000-1010.
35. Liu,F. et al. (2011) TNFalpha cooperates with IFN-gamma to repress BclxL expression to sensitize metastatic colon carcinoma cells to TRAILmediated apoptosis. PloS One, 6, e16241.