메뉴 건너뛰기




Volumn 13, Issue 10, 2011, Pages 1107-1117

Elevated citrate in pediatric astrocytomas with malignant progression

Author keywords

Astrocytoma; Citrate; Metabolism; MR spectroscopy; Pediatrics

Indexed keywords

CITRIC ACID;

EID: 80755125609     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nor087     Document Type: Article
Times cited : (29)

References (56)
  • 2
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science. 1956;123(3191):309- 314.
    • (1956) Science , vol.123 , Issue.3191 , pp. 309-314
    • Warburg, O.1
  • 3
    • 70449146922 scopus 로고
    • Citrate accumulation in slices of transplantable tumors of the rat
    • Busch H, Davis JR, Olle EW. Citrate accumulation in slices of transplantable tumors of the rat. Cancer Res. 1957;17(7):711-716.
    • (1957) Cancer Res. , vol.17 , Issue.7 , pp. 711-716
    • Busch, H.1    Davis, J.R.2    Olle, E.W.3
  • 4
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • Vander Heiden M, Cantley L, Thompson C. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science. 2009;324(5930):1029- 1033.
    • (2009) Science , vol.324 , Issue.5930 , pp. 1029-1033
    • Vander Heiden, M.1    Cantley, L.2    Thompson, C.3
  • 8
    • 33644915256 scopus 로고    scopus 로고
    • Brainstem gliomas
    • Gupta, N, Haas-Kogen, D, Banerjee, A, eds, Berlin/Heidelberg/New York: Springer
    • Pan E, Prados M. Brainstem Gliomas. In: Gupta, N, Haas-Kogen, D, Banerjee, A, eds. Pediatric CNS Tumors. Vol 3. Berlin/Heidelberg/New York: Springer; 2004:49-61.
    • (2004) Pediatric CNS Tumors , vol.3 , pp. 49-61
    • Pan, E.1    Prados, M.2
  • 9
    • 0028230455 scopus 로고
    • Necrosis in pontine gliomas: Radiation induced or natural history?
    • Nelson MD, Jr, Soni D, Baram TZ. Necrosis in pontine gliomas: radiation induced or natural history? Radiology. 1994;191(1):279-282. (Pubitemid 24098246)
    • (1994) Radiology , vol.191 , Issue.1 , pp. 279-282
    • Nelson Jr., M.D.1    Soni, D.2    Baram, T.Z.3
  • 10
    • 0042320363 scopus 로고    scopus 로고
    • Clinicopathological study of diffuse type brainstem gliomas: Analysis of 40 autopsy cases
    • DOI 10.2176/nmc.43.375
    • Yoshimura J, Onda K, Tanaka R, Takahashi H. Clinicopathological study of diffuse type brainstem gliomas: analysis of 40 autopsy cases. Neurol Med Chir. (Tokyo). 2003;43(8):375-382; discussion 382. (Pubitemid 37071218)
    • (2003) Neurologia Medico-Chirurgica , vol.43 , Issue.8 , pp. 375-382
    • Yoshimura, J.1    Onda, K.2    Tanaka, R.3    Takahashi, H.4
  • 11
    • 33344464494 scopus 로고    scopus 로고
    • Diffuse brainstem glioma in children: Critical review of clinical trials
    • DOI 10.1016/S1470-2045(06)70615-5, PII S1470204506706155
    • Hargrave D, Bartels U, Bouffet E. Diffuse brainstem glioma in children: critical review of clinical trials. Lancet Oncol. 2006;7(3):241-248. (Pubitemid 43286454)
    • (2006) Lancet Oncology , vol.7 , Issue.3 , pp. 241-248
    • Hargrave, D.1    Bartels, U.2    Bouffet, E.3
  • 18
    • 33344457137 scopus 로고    scopus 로고
    • Preoperative grading of gliomas by using metabolite quantification with high-spatial-resolution proton MR spectroscopic imaging
    • DOI 10.1148/radiol.2382041896
    • Stadlbauer A, Gruber S, Nimsky C, et al. Preoperative grading of gliomas by using metabolite quantification with high-spatial-resolution proton MR spectroscopic imaging. Radiology. 2006;238(3):958-969. (Pubitemid 43289928)
    • (2006) Radiology , vol.238 , Issue.3 , pp. 958-969
    • Stadlbauer, A.1    Gruber, S.2    Nimsky, C.3    Fahlbusch, R.4    Hammen, T.5    Buslei, R.6    Tomandl, B.7    Moser, E.8    Ganslandt, O.9
  • 20
    • 0034654511 scopus 로고    scopus 로고
    • Limitations of the World Health Organization classification of childhood supratentorial astrocytic tumors
    • DOI 10.1002/(SICI)1097-0142(20000315)88:6<1477::AID-CNCR28>3.0. CO;2-8
    • Gilles FH, Brown WD, Leviton A, et al. Limitations of the World Health Organization classification of childhood supratentorial astrocytic tumors. Children Brain Tumor Consortium. Cancer. 2000;88(6):1477-1483. (Pubitemid 30155188)
    • (2000) Cancer , vol.88 , Issue.6 , pp. 1477-1483
    • Gilles, F.H.1    Brown, W.D.2    Leviton, A.3    Tavare, C.J.4    Adelman, L.5    Rorke, L.B.6    Davis, R.L.7    Hedley-Whyte, T.E.8
  • 21
    • 77954697566 scopus 로고    scopus 로고
    • Isocitrate dehydrogenase 1 and 2 mutations in cancer: Alterations at a crossroads of cellular metabolism
    • Reitman Z, Yan H. Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. J Natl Cancer Inst. 2010;102(13):932-941.
    • (2010) J Natl Cancer Inst. , vol.102 , Issue.13 , pp. 932-941
    • Reitman, Z.1    Yan, H.2
  • 23
    • 73649088347 scopus 로고    scopus 로고
    • Mutant metabolic enzymes are at the origin of gliomas
    • Yan H, Bigner D, Velculescu V, Parsons D. Mutant metabolic enzymes are at the origin of gliomas. Cancer Res. 2009;69(24):9157-9159.
    • (2009) Cancer Res. , vol.69 , Issue.24 , pp. 9157-9159
    • Yan, H.1    Bigner, D.2    Velculescu, V.3    Parsons, D.4
  • 24
    • 0038268121 scopus 로고    scopus 로고
    • Correlation of apparent diffusion coefficient and computed tomography density in acute ischemic stroke
    • author reply e17-e18
    • Dóczi T, Schwarcz A. Correlation of apparent diffusion coefficient and computed tomography density in acute ischemic stroke. Stroke. 2003;34(5):e17-e18; author reply e17-e18.
    • (2003) Stroke , vol.34 , Issue.5
    • Dóczi, T.1    Schwarcz, A.2
  • 25
    • 34247530748 scopus 로고    scopus 로고
    • Malignant supratentorial astrocytoma treated with postoperative radiation therapy: Prognostic value of pretreatment quantitative diffusion-weighted MR imaging
    • DOI 10.1148/radiol.2432060450
    • Murakami R, Sugahara T, Nakamura H, et al. Malignant supratentorial astrocytoma treated with postoperative radiation therapy: prognostic value of pretreatment quantitative diffusion-weighted MR imaging. Radiology. 2007;243(2):493-499. (Pubitemid 46649706)
    • (2007) Radiology , vol.243 , Issue.2 , pp. 493-499
    • Murakami, R.1    Sugahara, T.2    Nakamura, H.3    Hirai, T.4    Kitajima, M.5    Hayashida, Y.6    Baba, Y.7    Oya, N.8    Kuratsu, J.-I.9    Yamashita, Y.10
  • 26
    • 33846700422 scopus 로고    scopus 로고
    • Malignant astrocytic tumors: Clinical importance of apparent diffusion coefficient in prediction of grade and prognosis
    • DOI 10.1148/radiol.2413051276
    • Higano S, Yun X, Kumabe T, et al. Malignant astrocytic tumors: clinical importance of apparent diffusion coefficient in prediction of grade and prognosis. Radiology. 2006;241(3):839-846. (Pubitemid 46190551)
    • (2006) Radiology , vol.241 , Issue.3 , pp. 839-846
    • Higano, S.1    Yun, X.2    Kumabe, T.3    Watanabe, M.4    Mugikura, S.5    Umetsu, A.6    Sato, A.7    Yamada, T.8    Takahashi, S.9
  • 28
    • 52949127312 scopus 로고    scopus 로고
    • An integrated genomic analysis of human glioblastoma multiforme
    • Parsons D, Jones S, Zhang X, et al. An integrated genomic analysis of human glioblastoma multiforme. Science. 2008;321(5897):1807-1812.
    • (2008) Science , vol.321 , Issue.5897 , pp. 1807-1812
    • Parsons, D.1    Jones, S.2    Zhang, X.3
  • 29
    • 65349150503 scopus 로고    scopus 로고
    • IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
    • Watanabe T, Nobusawa S, Kleihues P, Ohgaki H. IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. Am J Pathol. 2009;174(4):1149-1153.
    • (2009) Am J Pathol. , vol.174 , Issue.4 , pp. 1149-1153
    • Watanabe, T.1    Nobusawa, S.2    Kleihues, P.3    Ohgaki, H.4
  • 30
    • 64849098267 scopus 로고    scopus 로고
    • Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha
    • Zhao S, Lin Y, Xu W, et al. Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science. 2009;324(5924):261-265.
    • (2009) Science , vol.324 , Issue.5924 , pp. 261-265
    • Zhao, S.1    Lin, Y.2    Xu, W.3
  • 31
    • 60849115270 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations in gliomas
    • Yan H, Parsons D, Jin G, et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med. 2009;360(8):765-773.
    • (2009) N Engl J Med. , vol.360 , Issue.8 , pp. 765-773
    • Yan, H.1    Parsons, D.2    Jin, G.3
  • 32
    • 77953702324 scopus 로고    scopus 로고
    • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
    • Dang L, White D, Gross S, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 2010;465(7300):966.
    • (2010) Nature , vol.465 , Issue.7300 , pp. 966
    • Dang, L.1    White, D.2    Gross, S.3
  • 33
    • 77951239243 scopus 로고    scopus 로고
    • Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas
    • Beckner M, Fellows-Mayle W, Zhang Z, et al. Identification of ATP citrate lyase as a positive regulator of glycolytic function in glioblastomas. Int J Cancer. 2010;126(10):2282-2295.
    • (2010) Int J Cancer , vol.126 , Issue.10 , pp. 2282-2295
    • Beckner, M.1    Fellows-Mayle, W.2    Zhang, Z.3
  • 34
    • 50149097983 scopus 로고    scopus 로고
    • Hypoxia, HIF1 and glucose metabolism in the solid tumour
    • Denko N. Hypoxia, HIF1 and glucose metabolism in the solid tumour. Nat Rev Cancer. 2008;8(9):705-713.
    • (2008) Nat Rev Cancer , vol.8 , Issue.9 , pp. 705-713
    • Denko, N.1
  • 35
    • 3142631966 scopus 로고    scopus 로고
    • The human tumor microenvironment: Invasive (needle) measurement of oxygen and interstitial fluid pressure
    • DOI 10.1016/j.semradonc.2004.04.006, PII S1053429604000578
    • Milosevic M, Fyles A, Hedley D, Hill R. The human tumor microenvironment: invasive (needle) measurement of oxygen and interstitial fluid pressure. Semin Radiat Oncol. 2004;14(3):249-258. (Pubitemid 38903229)
    • (2004) Seminars in Radiation Oncology , vol.14 , Issue.3 , pp. 249-258
    • Milosevic, M.1    Fyles, A.2    Hedley, D.3    Hill, R.4
  • 36
    • 0024232289 scopus 로고
    • Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: Significance of elevated interstitial pressure
    • Jain R, Baxter L. Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure. Cancer Res. 1988;48(24 Pt 1):7022-7032. (Pubitemid 19013976)
    • (1988) Cancer Research , vol.48 , Issue.24 , pp. 7022-7032
    • Jain, R.K.1    Baxter, L.T.2
  • 37
    • 2542628099 scopus 로고    scopus 로고
    • Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
    • DOI 10.1158/0008-5472.CAN-04-0074
    • Tong R, Boucher Y, Kozin S, Winkler F, Hicklin D, Jain R. Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors. Cancer Res. 2004;64(11):3731-3736. (Pubitemid 38697278)
    • (2004) Cancer Research , vol.64 , Issue.11 , pp. 3731-3736
    • Tong, R.T.1    Boucher, Y.2    Kozin, S.V.3    Winkler, F.4    Hicklin, D.J.5    Jain, R.K.6
  • 38
    • 0035925098 scopus 로고    scopus 로고
    • Tumor hypoxia: Definitions and current clinical, biologic, and molecular aspects
    • Höckel M, Vaupel P. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. J Natl Cancer Inst. 2001;93(4):266-276. (Pubitemid 32219813)
    • (2001) Journal of the National Cancer Institute , vol.93 , Issue.4 , pp. 266-276
    • Hockel, M.1    Vaupel, P.2
  • 39
    • 0029775242 scopus 로고    scopus 로고
    • Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix
    • Hockel M, Schlenger K, Aral B, Mitze M, Schaffer U, Vaupel P. Association between tumor hypoxia and malignant progression in advanced cancer of the uterine cervix. Cancer Res. 1996;56(19):4509-4515. (Pubitemid 26330463)
    • (1996) Cancer Research , vol.56 , Issue.19 , pp. 4509-4515
    • Hockel, M.1    Schlenger, K.2    Aral, B.3    Mitze, M.4    Schaffer, U.5    Vaupel, P.6
  • 41
    • 0030067857 scopus 로고    scopus 로고
    • Tumor hypoxia and heterogeneity: Challenges and opportunities for the future
    • DOI 10.1016/S1053-4296(96)80036-1
    • Sutherland RM, Ausserer WA, Murphy BJ, Laderoute KR. Tumor Hypoxia and Heterogeneity: Challenges and Opportunities for the Future. Semin Radiat Oncol. 1996;6(1):59-70. (Pubitemid 26029374)
    • (1996) Seminars in Radiation Oncology , vol.6 , Issue.1 , pp. 59-70
    • Sutherland, R.M.1    Ausserer, W.A.2    Murphy, B.J.3    Laderoute, K.R.4
  • 44
    • 0034485963 scopus 로고    scopus 로고
    • Canavan's spongiform leukodystrophy: A clinical anatomy of a genetic metabolic CNS disease
    • DOI 10.1385/JMN:15:2:61
    • Baslow MH. Canavan's spongiform leukodystrophy: a clinical anatomy of a genetic metabolic CNS disease. Journal of Molecular Neuroscience. 2000;15(2):61-69. (Pubitemid 32108676)
    • (2000) Journal of Molecular Neuroscience , vol.15 , Issue.2 , pp. 61-69
    • Baslow, M.H.1
  • 45
    • 0000356642 scopus 로고
    • Studies on the distribution of N-acetyl-L-aspartic acid in brain
    • Tallan HH. Studies on the distribution of N-acetyl-L-aspartic acid in brain. J Biol Chem. 1957;224(1):41-45.
    • (1957) J Biol Chem. , vol.224 , Issue.1 , pp. 41-45
    • Tallan, H.H.1
  • 46
    • 0141954157 scopus 로고    scopus 로고
    • Choline phospholipid metabolism: A target in cancer cells?
    • DOI 10.1002/jcb.10659
    • Ackerstaff E, Glunde K, Bhujwalla ZM. Choline phospholipid metabolism: a target in cancer cells? J Cell Biochem. 2003;90(3):525-533. (Pubitemid 37243700)
    • (2003) Journal of Cellular Biochemistry , vol.90 , Issue.3 , pp. 525-533
    • Ackerstaff, E.1    Glunde, K.2    Bhujwalla, Z.M.3
  • 47
    • 0033371680 scopus 로고    scopus 로고
    • Tumour phospholipid metabolism
    • DOI 10.1002/(SICI)1099-1492(199911)12:7<413::AID-NBM587>3.0.CO;2-U
    • Podo F. Tumour phospholipid metabolism. NMR Biomed. 1999;12(7):413-439. (Pubitemid 30016999)
    • (1999) NMR in Biomedicine , vol.12 , Issue.7 , pp. 413-439
    • Podo, F.1
  • 49
    • 0029666215 scopus 로고    scopus 로고
    • 1H MRS is vivo in brain tumors: Experience of the Siemens Cooperative Clinical Trial
    • Negendank W, Sauter R. Intratumoral lipids in 1H MRS in vivo in brain tumors: experience of the Siemens cooperative clinical trial. Anticancer Res. 1996;16(3 B):1533-1538. (Pubitemid 26257823)
    • (1996) Anticancer Research , vol.16 , Issue.3 B , pp. 1533-1538
    • Negendank, W.1    Sauter, R.2
  • 50
    • 0026922513 scopus 로고
    • Studies of human tumors by MRS: A review
    • Negendank WG. Studies of human tumors by MRS: a review. NMR in Biomedicine. 1992;5:303-324.
    • (1992) NMR in Biomedicine , vol.5 , pp. 303-324
    • Negendank, W.G.1
  • 51
    • 33748050797 scopus 로고    scopus 로고
    • Longitudinal MR spectroscopic imaging of pediatric diffuse pontine tumors to assess tumor aggression and progression
    • Thakur SB, Karimi S, Dunkel IJ, Koutcher JA, Huang W. Longitudinal MR Spectroscopic Imaging of Pediatric Diffuse Pontine Tumors to Assess Tumor Aggression and Progression. AJNR Am J Neuroradiol. 2006;27(4):806-809. (Pubitemid 44897726)
    • (2006) American Journal of Neuroradiology , vol.27 , Issue.4 , pp. 806-809
    • Thakur, S.B.1    Karimi, S.2    Dunkel, I.J.3    Koutcher, J.A.4    Huang, W.5
  • 53
    • 0242580198 scopus 로고    scopus 로고
    • Metabolite ratios to assumed stable creatine level may confound the quantification of proton brain MR spectroscopy
    • DOI 10.1016/S0730-725X(03)00181-4
    • Li BS, Wang H, Gonen O. Metabolite ratios to assumed stable creatine level may confound the quantification of proton brain MR spectroscopy. Magn Reson Imaging. 2003;21(8):923-928. (Pubitemid 37377485)
    • (2003) Magnetic Resonance Imaging , vol.21 , Issue.8 , pp. 923-928
    • Li, B.S.Y.1    Wang, H.2    Gonen, O.3
  • 54
    • 0034118137 scopus 로고    scopus 로고
    • Correlation between choline level measured by proton MR spectroscopy and Ki-67 labeling index in gliomas
    • Shimizu H, Kumabe T, Shirane R, Yoshimoto T. Correlation between choline level measured by proton MR spectroscopy and Ki-67 labeling index in gliomas. AJNR Am J Neuroradiol. 2000;21(4):659-665. (Pubitemid 30210427)
    • (2000) American Journal of Neuroradiology , vol.21 , Issue.4 , pp. 659-665
    • Shimizu, H.1    Kumabe, T.2    Shirane, R.3    Yoshimoto, T.4
  • 55
    • 0034065534 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy reflects cellular proliferative activity in astrocytomas
    • Tamiya T, Kinoshita K, Ono Y, Matsumoto K, Furuta T, Ohmoto T. Proton magnetic resonance spectroscopy reflects cellular proliferative activity in astrocytomas. Neuroradiology. 2000;42(5):333-338. (Pubitemid 30265348)
    • (2000) Neuroradiology , vol.42 , Issue.5 , pp. 333-338
    • Tamiya, T.1    Kinoshita, K.2    Ono, Y.3    Matsumoto, K.4    Furuta, T.5    Ohmoto, T.6
  • 56
    • 0030983951 scopus 로고    scopus 로고
    • Increased choline signal coinciding with malignant degeneration of cerebral gliomas: A serial proton magnetic resonance spectroscopy imaging study
    • Tedeschi G, Lundbom N, Raman R, et al. Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study. J Neurosurg. 1997;87(4):516-524. (Pubitemid 27430397)
    • (1997) Journal of Neurosurgery , vol.87 , Issue.4 , pp. 516-524
    • Tedeschi, G.1    Lundbom, N.2    Raman, R.3    Bonavita, S.4    Duyn, J.H.5    Alger, J.R.6    Di Chiro, G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.