Metabolism of diffuse intrinsic brainstem gliomas in children

Neuro-Oncology

Volumn 10, Issue 1, 2008, Pages 32-44

  Panigrahy, Ashok ^a   Nelson Jr , Marvin D ^a   Finlay, Jonathan L ^a   Sposto, Richard ^a   Krieger, Mark D ^a   Gilles, Floyd H ^a   Blüml, Stefan ^a,b  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b Rudi Schulte Research Institute   (United States)

Author keywords

Brainstem gliomas; Disease progression; Metabolism; MR spectroscopy; Pediatrics

Indexed keywords

CHOLINE; CREATINE; INOSITOL; LIPID; N ACETYLASPARTIC ACID; TUMOR MARKER;

ADOLESCENT; ARTICLE; ASTROCYTOMA; BRAIN STEM TUMOR; CANCER GROWTH; CANCER PATIENT; CLINICAL ARTICLE; CLINICAL FEATURE; COMPARATIVE STUDY; CONTROLLED STUDY; DETERIORATION; FEMALE; GLIOBLASTOMA; GLIOMA; HUMAN; IN VIVO STUDY; MALE; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRESCHOOL CHILD; RETROSPECTIVE STUDY; SCHOOL CHILD;

ADOLESCENT; ASTROCYTOMA; BRAIN NEOPLASMS; BRAIN STEM NEOPLASMS; CHILD; CHILD, PRESCHOOL; FEMALE; GLIOMA; HUMANS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RETROSPECTIVE STUDIES;

EID: 39149096832     PISSN: 15228517     EISSN: None     Source Type: Journal    
DOI: 10.1215/15228517-2007-042     Document Type: Article

References (54)

1. Farmer JP, Montes JL, Freeman CR, Meagher-Villemure K, Bond C, O'Gorman AM. Brainstem gliomas: a ten-year institutional review. Pediatr Neurosurg. 2001;34:206-214.
2. Freeman CR, Farmer JP. Pediatric brain stem gliomas: a review. Int J Radiat Oncol Biol Phys. 1998;40:265-271.
3. Hargrave D, Bartels U, Bouffet E. Diffuse brainstem glioma in children: critical review of clinical trials. Lancet Oncol. 2006;7:241-248.
4. Mandell LR, Kadota R, Freeman C, et al. There is no role for hyperfractionated radiotherapy in the management of children with newly diagnosed diffuse intrinsic brainstem tumors: results of a Pediatric Oncology Group phase III trial comparing conventional vs. hyperfractionated radiotherapy. Int J Radiat Oncol Biol Phys. 1999;43:959-964.
5. Nelson MD Jr, Soni D, Baram TZ. Necrosis in pontine gliomas: radiation induced or natural history? Radiology. 1994;191:279-282.
6. Pan E, Prados M. In: Gupta N, Haas-Kogen D, Banerjee A, eds. Pediatric CNS Tumors. Vol 3. New York: Springer-Verlag; 2004:49-61.
7. Rubin G, Michowitz S, Horev, G, et al. Pediatric brain stem gliomas: an update. Childs Nerv Syst. 1998;14:167-173.
8. Yoshimura J, Onda K, Tanaka R, Takahashi H. Clinicopathological study of diffuse type brainstem gliomas: analysis of forty autopsy cases. Neurol Med Chir (Tokyo). 2003;43:375-382; discussion 382.
9. Carrie C, Negrier S, Gomez F, et al. Diffuse medulla oblongata and pontine gliomas in childhood: a review of thirty-seven cases. Bull Cancer. 2004;91:E167-E183.
10. Lenard HG Engelbrecht V, Janssen G, Wechsler W, Tautz C. Complete remission of a diffuse pontine glioma. Neuropediatrics. 1998;29:328-330.
11. Albright AL, Packer RJ, Zimmerman R, Rorke LB, Boyett J, Hammond GD. Magnetic resonance scans should replace biopsies for the diagnosis of diffuse brain stem gliomas: a report from the Children's Cancer Group. Neurosurgery. 1993;33:1026-1029; discussion 1029-1030.
12. Barkovich AJ, Krischer J, Kun LE, et al. Brain stem gliomas: a classification system based on magnetic resonance imaging. Pediatr Neurosurg. 1990;16:73-83.
13. Laprie A, Pirzkall A, Haas-Kogan D A, et al. Longitudinal multivoxel MR spectroscopy study of pediatric diffuse brainstem gliomas treated with radiotherapy. Int J Radiat Oncol Biol Phys. 2005;62:20-31.
14. Ross B, Bluml S. Magnetic resonance spectroscopy of the human brain. Anatomical Record. 2001;265:54-84.
15. Howe FA, Barton SJ, Cudlip SA, et al. Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy. Magn Reson Med. 2003;49:223-232.
16. Li X, Jin H, Lu Y, Oh J, Chang S, Nelson SJ. Identification of MRI and 1H MRSI parameters that may predict survival for patients with malignant gliomas. NMR Biomed. 2004;17:10-20.
17. Negendank WG. Studies of human tumors by MRS: a review. NMR in Biomedicine. 1992;5:303-324.
18. Negendank WG, Sauter R, Brown TR, et al. Proton magnetic resonance spectroscopy in patients with glial tumors: a multicenter study. J Neurosurg. 1996;84:449-458.
19. Shimizu H, Kumabe T, Shirane R, Yoshimoto T. Correlation between choline level measured by proton MR spectroscopy and Ki-67 labeling index in gliomas. AJNR Am J Neuroradiol. 2000;21:659-665.
20. Stadibauer A, Gruber S, Nimsky C, et al. Preoperative grading of gliomas by using metabolite quantification with high-spatial-resolution proton MR spectroscopic imaging. Radiology. 2006;238:958-969.
21. Tamiya T, Kinoshita K, Ono Y, Matsumoto K, Furuta T, Ohmoto T. Proton magnetic resonance spectroscopy reflects cellular proliferative activity in astrocytomas. Neuroradiology. 2000;42:333-338.
22. Tedeschi G, Lundbom N, Raman R, et al. Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study. J Neurosurg. 1997;87:516-524.
23. Curless RG, Bowen BC, Pattany PM, Gonik R, Kramer DL. Magnetic resonance spectroscopy in childhood brainstem tumors. Pediatr Neurol. 2002;26:374-378.
24. Thakur SB, Karimi S, Dunkel IJ, Koutcher JA, Huang W. Longitudinal MR spectroscopic imaging of pediatric diffuse pontine tumors to assess tumor aggression and progression. AJNR Am J Neuroradiol. 2006;27:806-809.
25. Jallo GI, Biser-Rohrbaugh A., Freed D. Brainstem gliomas. Childs Nerv Syst. 2004;20:143-153.
26. Kovanlikaya A, Panigrahy A, Krieger MD, et al. Untreated pediatric primitive neuroectodermal tumor in vivo: quantitation of taurine with MR spectroscopy. Radiology. 2005;236:1020-1025.
27. Panigrahy A, Krieger MD, Gonzalez-Gomez I, et al. Quantitative short echo time 1H-MR spectroscopy of untreated pediatric brain tumors: preoperative diagnosis and characterization. AJNR Am J Neuroradiol. 2006;27:560-572.
28. Ernst T, Kreis R, Ross BD. Absolute quantitation of water and metabolites in the human brain. I. Compartments and water. J Magn Reson. 1993;102:1-8.
29. Astrakas LG, Zurakowski D, Tzika AA, et al. Noninvasive magnetic resonance spectroscopic imaging biomarkers to predict the clinical grade of pediatric brain tumors. Clin Cancer Res. 2004;10:8220-8228.
30. Wang ZJ, Zimmerman RA. Proton MR spectroscopy of pediatric brain metabolic disorders. Neuroimaging Clin N Am. 1998;8:781-807.
31. Isobe T, Matsumura A, Anno I, et al. Changes in 1H-MRS in glioma patients before and after irradiation: the significance of quantitative analysis of choline-containing compounds. No Shinkei Geka. 2003;31:167-172.
32. Preul MC, Leblanc R, Caramanos Z, Kasrai R, Narayanan S, Arnold DL. Magnetic resonance spectroscopy guided brain tumor resection: differentiation between recurrent glioma and radiation change in two diagnostically difficult cases. Can J Neurol Sci. 1998;25:13-22.
33. Schlemmer HP, Bachert P, Herfarth KK, Zuna I, Debus J, van Kaick G. Proton MR spectroscopic evaluation of suspicious brain lesions after stereotactic radiotherapy. AJNR Am J Neuroradiol. 2001;22:1316-1324.
34. Wald LL, Nelson SJ, Day MR, et al. Serial proton magnetic resonance spectroscopy imaging of glioblastoma multiforme after brachytherapy. J Neurosurg. 1997;87:525-534.
35. Albers MJ, Krieger MD, Gonzalez-Gomez I, et al. Proton-decoupled (31)P MRS in untreated pediatric brain tumors. Magn Reson Med. 2005;53:22-29.
36. Bluml S, Seymour KJ, Ross BD. Developmental changes in choline-and ethanolamine-containing compounds measured with proton-decoupled (31)P MRS in in vivo human brain. Magn Reson Med. 1999;42:643-654.
37. Glunde K, Jie C, Bhujwalla ZM. Molecular causes of the aberrant choline phospholipid metabolism in breast cancer. Cancer Res. 2004;64:4270-4276.
38. Podo F. Tumour phospholipid metabolism. NMR Biomed. 1999;12:413-439.
39. Kuesel AC, Sutherland GR, Halliday W, Smith IC. 1H MRS of high grade astrocytomas: mobile lipid accumulation in necrotic tissue. NMR Biomed. 1994;7:149-155.
40. Barba I, Cabanas ME, Arus C. The relationship between nuclear magnetic resonance-visible lipids, lipid droplets, and cell proliferation in cultured C6 cells. Cancer Res. 1999;59:1861-1868.
41. Remy C, Fouilhe N, Barba I, et al. Evidence that mobile lipids detected in rat brain glioma by 1H nuclear magnetic resonance correspond to lipid droplets. Cancer Res. 1997;57:407-414.
42. Castillo M, Smith JK, Kwock L. Correlation of myo-inositol levels and grading of cerebral astrocytomas. AJNR Am J Neuroradiol. 2000;21:1645-1649.
43. Packer RJ, Boyett JM, Zimmerman RA, et al. Outcome of children with brain stem gliomas after treatment with 7800 cGy of hyperfractionated radiotherapy. A Childrens Cancer Group Phase I/II Trial. Cancer. 1994;74:1827-1834.
44. Matson D. In: Neurosurgery of Infancy and Childhood. 2nd ed. Springfield, IL: Charles C Thomas; 1969:469-477.
45. Helms G. A precise and user-independent quantification technique for regional comparison of single volume proton MR spectroscopy of the human brain. NMR Biomed. 2000;13:398-406.
46. Horska A, Calhoun VD, Bradshaw DH, Barker PB. Rapid method for correction of CSF partial volume in quantitative proton MR spectroscopic imaging. Magn Reson Med. 2002;48:555-558.
47. Jansen JF, Backes WH, Nicolay K, Kooi ME. 1H MR spectroscopy of the brain: absolute quantification of metabolites. Radiology. 2006;240318-332.
48. Keevil SF, Barbiroli B, Brooks JC, et al. Absolute metabolite quantification by in vivo NMR spectroscopy. II. A multicentre trial of protocols for in vivo localised proton studies of human brain. Magn Reson Imaging. 1998;16:1093-1106.
49. Kreis R, Ernst T, Ross BD. Absolute quantitation of water and metabolites in the human brain. II. Metabolite concentrations. J Magn Reson. 1993;102:9-19.
50. Kreis R, Hofmann L, Kuhlmann B, Boesch C, Bossi E, Hueppi PS. Brain metabolite composition during early human brain development as measured by quantitative in vivo 1H magnetic resonance spectroscopy. Magn Reson Med. 2002;48:949-958.
51. Pouwels PJW, Frahm J. Regional metabolite concentrations in human brain as determined by quantitative localized proton MRS. Magn Reson Med. 1998;39:53-60.
52. Soher BJ, Hurd RE, Sailasuta N, Barker PB. Quantitation of automated single-voxel proton MRS using cerebral water as an internal reference. Magn Reson Med. 1996;36:335-339.
53. Li BS, Wang H, Gonen O. Metabolite ratios to assumed stable creatine level may confound the quantification of proton brain MR spectroscopy. Magn Reson Imaging. 2003;21:923-928.
54. Schirmer T, Auer DP. On the reliability of quantitative clinical magnetic resonance spectroscopy of the human brain. NMR Biomed. 2000;13:28-36.