Treatment of small cell lung cancer with TRA-8 in combination with cisplatin and radiation

Radiotherapy and Oncology

Volumn 101, Issue 1, 2011, Pages 183-189

  Bonner, James A ^a   Willey, Christopher D ^a   Yang, Eddy S ^a   Dobelbower, Michael C ^a   Sanford, Leisa L ^a   Bright, Sheila J ^a   Buchsbaum, Donald J ^a   Raisch, Kevin P ^a  

^a The University of Alabama at Birmingham   (United States)

Author keywords

Anti DR5; Cisplatin; Death receptor; Radiation; Small Cell

Indexed keywords

CASPASE; CISPLATIN; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FLUORESCEIN ISOTHIOCYANATE; LIPOCORTIN 5; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY TRA 8; PROCASPASE 8; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASSAY; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IC 50; IMMUNOBLOTTING; IN VITRO STUDY; LUNG SMALL CELL CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL; TUMOR CELL; TUMOR XENOGRAFT;

ANIMALS; ANNEXIN A5; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CHEMORADIOTHERAPY; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; RADIATION, IONIZING; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; SENSITIVITY AND SPECIFICITY; SMALL CELL LUNG CARCINOMA; TREATMENT OUTCOME;

EID: 80655149134     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2011.05.083     Document Type: Article

References (23)

1. D. Yee, J. Hanson, and C. Butts Phase I dose escalation trial of hypofractionated limited-field external beam thoracic radiotherapy for limited-stage small cell carcinoma of the lung Radiother Oncol 96 2010 78 83
2. R. Handrick, U. Ganswindt, and H. Faltin Combined action of celecoxib and ionizing radiation in prostate cancer cells is independent of pro-apoptotic Bax Radiother Oncol 90 2009 413 421
3. N. Shivapurkar, J. Reddy, P.M. Chaudhary, and A.F. Gazdar Apoptosis and lung cancer: a review J Cell Biochem 88 2003 885 898 (Pubitemid 36337033)
4. S. Shamimi-Noori, W.S. Yeow, and M.F. Ziauddin Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway Cancer Gene Ther 15 2008 356 370 (Pubitemid 351693223)
5. O. Vondalova Blanarova, I. Jelinkova, and A. Szoor Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway Carcinogenesis 32 2011 42 51
6. A. Vaculova, V. Kaminskyy, E. Jalalvand, O. Surova, and B. Zhivotovsky Doxorubicin, etoposide sensitize small cell lung carcinoma cells expressing caspase-8 to TRAIL Mol Cancer 9 2010 87
7. N.V. Rajeshkumar, Z.A. Rasheed, and E. Garcia-Garcia A combination of DR5 agonistic monoclonal antibody with gemcitabine targets pancreatic cancer stem cells and results in long-term disease control in human pancreatic cancer model Mol Cancer Ther 9 2010 2582 2592
8. J.E. Kendrick, J.M. Straughn Jr., and P.G. Oliver Anti-tumor activity of the TRA-8 anti-DR5 antibody in combination with cisplatin in an ex vivo human cervical cancer model Gynecol Oncol 108 2008 591 597
9. J.H. Maduro, E.G. de Vries, G.J. Meersma, B.M. Hougardy, A.G. Van der Zee, and S. de Jong Targeting pro-apoptotic trail receptors sensitizes HeLa cervical cancer cells to irradiation-induced apoptosis Int J Radiat Oncol Biol Phys 72 2008 543 552
10. J. Chen, X. Sun, W. Yang, G. Jiang, and X. Li Cisplatin-enhanced sensitivity of glioblastoma multiform U251 cells to adenovirus-delivered TRAIL in vitro Tumour Biol 31 2010 613 622
11. T. Hori, T. Kondo, and M. Kanamori Ionizing radiation enhances tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through up-regulations of death receptor 4 (DR4) and death receptor 5 (DR5) in human osteosarcoma cells J Orthop Res 28 2010 739 745
12. D.J. Buchsbaum, T. Zhou, and W.E. Grizzle Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model Clin Cancer Res 9 2003 3731 3741 (Pubitemid 37169242)
13. M.A. Sciamanna, G.E. Griesmann, C.L. Williams, and V.A. Lennon Nicotinic acetylcholine receptors of muscle and neuronal (alpha7) types coexpressed in a small cell lung carcinoma J Neurochem 69 1997 2302 2311 (Pubitemid 27495415)
14. J.A. Bonner, H.Q. Trummell, C.D. Willey, B.A. Plants, and K.P. Raisch Inhibition of STAT-3 results in radiosensitization of human squamous cell carcinoma Radiother Oncol 92 2009 339 344
15. M.N. Saleh, K.P. Raisch, and M.A. Stackhouse Combined modality therapy of A431 human epidermoid cancer using anti-EGFr antibody C225 and radiation Cancer Biother Radiopharm 14 1999 451 463 (Pubitemid 30029793)
16. J.A. Bonner, D.J. Buchsbaum, and B.E. Rogers Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells Int J Radiat Oncol Biol Phys 58 2004 950 958 (Pubitemid 38221155)
17. S. Hopkins-Donaldson, A. Ziegler, and S. Kurtz Silencing of death receptor and caspase-8 expression in small cell lung carcinoma cell lines and tumors by DNA methylation Cell Death Differ 10 2003 356 364 (Pubitemid 36582373)
18. J.H. Song, D.K. Song, B. Pyrzynska, K.C. Petruk, E.G. Van Meir, and C. Hao TRAIL triggers apoptosis in human malignant glioma cells through extrinsic and intrinsic pathways Brain Pathol 13 2003 539 553 (Pubitemid 37420698)
19. N. Shivapurkar, J. Reddy, and H. Matta Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification Oncogene 21 2002 8510 8514 (Pubitemid 36054892)
20. S. Shetty, B.A. Graham, and J.G. Brown Transcription factor NF-kappaB differentially regulates death receptor 5 expression involving histone deacetylase 1 Mol Cell Biol 25 2005 5404 5416 (Pubitemid 40853578)
21. W.S. Tsai, W.S. Yeow, A. Chua, R.M. Reddy, D.M. Nguyen, and D.S. Schrump Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin Mol Cancer Ther 5 2006 2977 2990 (Pubitemid 46092039)
22. I.A. Kim, M. No, and J.M. Lee Epigenetic modulation of radiation response in human cancer cells with activated EGFR or HER-2 signaling: potential role of histone deacetylase 6 Radiother Oncol 92 2009 125 132
23. F. Rodel, B. Frey, and G. Capalbo Discontinuous induction of X-linked inhibitor of apoptosis in EA.hy.926 endothelial cells is linked to NF-kappaB activation and mediates the anti-inflammatory properties of low-dose ionising-radiation Radiother Oncol 97 2010 346 351