Ionizing radiation enhances Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-induced apoptosis through up-regulations of Death Receptor 4 (DR4) and Death Receptor 5 (DR5) in human osteosarcoma cells

Journal of Orthopaedic Research

Volumn 28, Issue 6, 2010, Pages 739-745

  Hori, Takeshi ^a   Kondo, Takashi ^a   Kanamori, Masahiko ^a   Tabuchi, Yoshiaki ^b   Ogawa, Ryohei ^a   Zhao, Qing Li ^a   Ahmed, Kanwal ^a   Yasuda, Taketoshi ^a   Seki, Shoji ^a   Suzuki, Kayo ^a   Kimura, Tomoatsu ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Apoptosis; DR5; Ionizing radiation; TRAIL

Indexed keywords

CASPASE 3; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FLICE INHIBITORY PROTEIN; PROTEIN BID; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; X LINKED INHIBITOR OF APOPTOSIS;

APOPTOSIS; ARTICLE; CELL VIABILITY; DRUG MECHANISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IONIZING RADIATION; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; BONE NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; OSTEOSARCOMA; PROMOTER REGIONS, GENETIC; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RECEPTORS, TUMOR NECROSIS FACTOR; RNA, MESSENGER; TNF-RELATED APOPTOSIS-INDUCING LIGAND; UP-REGULATION;

EID: 77951478417     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21056     Document Type: Article

References (23)

1. Fletcher CDM, Unni KK, Mertens F. 2002. World Health Organization classification of tumors. Pathology and genetics of tumours of soft tissue and bone. In: Raymond AK, Ayala AG, Knuutila S, editors. Conventional osteosarcoma. Lyon: IARC Press; p 264-270.
2. Wiley SR, Schooley K, Smolak PJ, et al. 1995. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3:673-682. (Pubitemid 26091143)
3. Pitti RM, Marsters SA, Ruppert S, et al. 1996. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 271:12687-12690. (Pubitemid 26175834)
4. Suliman A, Lam A, Datta R, et al. 2001. Intracellular mechanisms of TRAIL: apoptosis through mitochondrialdependent and -independent pathways. Oncogene 20:2122-2133. (Pubitemid 32424006)
5. Kataoka T. 2005. The caspase-8 modulator c-FLIP. Crit Rev Immunol 25:31-58.
6. Deveraux QL, Leo E, Stennicke HR, et al. 1999. Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases. EMBO J 18:5242-5251. (Pubitemid 29465575)
7. Siervo-Sassi RR, Marrangoni AM, Feng X, et al. 2003. Physiological and molecular effects of Apo2L/TRAIL and cisplatin in ovarian carcinoma cell lines. Cancer Lett 190: 61-72. (Pubitemid 36106557)
8. Hotta T, Suzuki H, Nagai S, et al. 2003. Chemotherapeutic agents sensitize sarcoma cell lines to tumor necrosis factorrelated apoptosis-inducing ligand-induced caspase-8 activation, apoptosis and loss of mitochondrial membrane potential. J Orthop Res 21:949-957. (Pubitemid 37045575)
9. Chinnaiyan AM, Prasad U, Shankar S, et al. 2000. Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc Natl Acad Sci USA 97:1754-1759. (Pubitemid 30118515)
10. Marini P, Schmid A, Jendrossek V, et al. 2005. Irradiation specifically sensitizes solid tumour cell lines to TRAIL mediated apoptosis. BMC Cancer 5:5. (Pubitemid 40180314)
11. Hamasu T, Inanami O, Asanuma T, et al. 2005. Enhanced induction of apoptosis by combined treatment of human carcinoma cells with X-rays and death receptor agonists. J Radiat Res 46:103-110. (Pubitemid 40780155)
12. van Heerde WL, de Groot PG, Reutelingsperger CPM. 1995. The complexity of the phospholipid binding protein annexin V. Thromb Haemost 73:172-179.
13. Sambrook J, Russell DW. 2001. Molecular cloning: a laboratory manual. 3rd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press.
14. Yoshida T, Maeda A, Tani N, et al. 2001. Promoter structure and transcription initiation sites of the human death receptor 5/TRAIL-R2 gene. FEBS Lett 507:381-385. (Pubitemid 33030270)
15. Falschlehner C, Emmerich CH, Gerlach B, et al. 2007. TRAIL signaling: decisions between life and death. Int J Biochem Cell Biol 39:1462-1475. (Pubitemid 47031030)
16. Strasser A, O'Connor L, Dixit VM. 2000. Apoptosis signaling. Annu Rev Biochem 69:217-245.
17. Fernandes-Alnemri T, Litwack G, Alnemri ES. 1994. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1β-converting enzyme. J Biol Chem 269:30716-30764. (Pubitemid 24377553)
18. Suzuki H, Hotta T, Koyama T, et al. 2003. Retrovirusmediated transduction of TRAIL and chemotherapeutic agents co-operatively induce apoptotic cell death in both sarcoma and myeloma cells. Anticancer Res 23:3247-3253. (Pubitemid 36975420)
19. Spee B, Jonkers MD, Arends B, et al. 2006. Specific downregulation of XIAP with RNA interference enhances the sensitivity of canine tumor cell-lines to TRAIL and doxorubicin. Mol Cancer 5:3.
20. Valen FV, Fulda S, Schäfer KL, et al. 2003. Selective and nonselective toxicity of TRAIL/Apo2L combined with chemotherapy in human bone tumour cells vs. normal human cells. Int J Cancer 107:929-940. (Pubitemid 37429834)
21. Pespeni MH, Hodnett M, Abayasiriwardana KS, et al. 2007. Sensitization of mesothelioma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by heat stress via the inhibition of the 3-phosphoinositidedependent kinase 1/Akt pathway. Cancer Res 67:2865-2871. (Pubitemid 46548977)
22. Liu X, Yue P, Khuri FP, et al. 2004. p53 upregulates death receptor 4 expression through an intronic p53 binding site. Cancer Res 64:5078-5083. (Pubitemid 39006522)
23. Irmler M, Thome M, Hahne M, et al. 1997. Inhibition of death receptor signals by cellular FLIP. Nature 388:190-195. (Pubitemid 27297457)