Nicotinic acetylcholine receptors of muscle and neuronal (α7) types coexpressed in a small cell lung carcinoma

Journal of Neurochemistry

Volumn 69, Issue 6, 1997, Pages 2302-2311

  Sciamanna, Michele A ^a   Griesmann, Guy E ^a   Williams, Carol L ^b   Lennon, Vanda A ^a  

^a MAYO CLINIC   (United States)

^b GUTHRIE RESEARCH INSTITUTE   (United States)

Author keywords

Myasthenia gravis; Nicotinic acetylcholine receptor; Bungarotoxin receptors; 7 subunit

Indexed keywords

CALCIUM CHANNEL; NICOTINIC RECEPTOR; TUBOCURARINE CHLORIDE;

ARTICLE; AUTOIMMUNITY; BINDING AFFINITY; LIGAND BINDING; LUNG SMALL CELL CANCER; MYASTHENIA GRAVIS; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SODIUM TRANSPORT; XENOGRAFT;

EID: 0030692732     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69062302.x     Document Type: Article

References (50)

1. Alkondon M., Pereira E. F. R., Wonnacott S., and Albuquerque E. X. (1992) Blockade of nicotinic currents in hippocampal neurons defines methyllycaconitine as a potent and specific receptor antagonist. Mol. Pharmacol. 41, 802-808.
2. Amar M., Thomas P., Johnson C., Lunt G. G., and Wonnacott S. (1993) Agonist pharmacology of the neuronal α7 nicotinic receptor expressed in Xenopus oocytes. FEBS Lett. 327, 284-288.
3. Anand R., Peng X., and Lindstrom J. (1993) Homomeric and native α7 acetylcholine receptors exhibit remarkably similar but nonidentical pharmacological properties, suggesting that the native receptor is a heteromeric protein complex. FEBS Lett. 327, 241-246.
4. Blount P. and Merlie J. P. (1990) Mutational analysis of mouse and muscle nicotinic acetylcholine receptor subunit assembly. J. Cell Biol. 111, 2613-2622.
5. Bruns R. F., Lawson-Wendling K., and Pugsley T. A. (1983) A rapid filtration assay for soluble receptors using polyethylenimine-treated filters. Anal. Biochem. 132, 74-81.
6. Carney D. N. (1992) Biology of small-cell lung cancer. Lancet 339, 843-846.
7. Castro N. G. and Albuquerque E. X. (1993) Brief-lifetime, fast-inactivating ion channels account for the α-bungarotoxin-sensitive nicotinic response in hippocampal neurons. Neurosci. Lett. 164, 137-140.
8. Cattaneo M. G., Codignola A., Vincenti L. M., Clementi F., and Sher E. (1993) Nicotine stimulates a serotonergic autocrine loop in human small-cell lung carcinoma. Cancer Res. 53, 5566-5568.
9. 5-nicotinic receptor subunit gene are expressed in neuronal and nonneuronal human cell lines. Proc. Natl. Acad. Sci. USA 89, 1572-1576.
10. Codignola A., Tarroni P., Clementi F., Polio A., Lovallo M., Carbone E., and Sher E. (1993) Calcium channel subtypes controlling serotonin release from human small cell lung carcinoma cell lines. J. Biol. Chem. 268, 26240-26247.
11. Codignola A., Tarroni P., Cattaneo M. G., Vicentini L. M., Clementi F., and Sher E. (1994) Serotonin release and cell proliferation are under the control of α-bungarotoxin-sensitive nicotinic receptors in small-cell lung carcinoma cell lines. FEBS Lett. 342, 286-290.
12. Codignola A., McIntosh M., Cattaneo M. G., Vicentini L. M., Clementi F., and Sher E. (1996) α-Conotoxin Imperialis I inhibits nicotine-evoked hormone release and cell proliferation in human endocrine carcinoma cells. Neurosci. Lett. 206, 53-56.
13. Conroy W. G., Saedi M. S., and Lindstrom J. (1990) TE671 cells express an abundance of a partially mature acetylcholine receptor α subunit which has characteristics of an assembly intermediate. J. Biol. Chem. 265, 21642-21651.
14. Corriveau R. A., Romano S. J., Conroy W. A., Oliva L., and Berg D.K. (1995) Expression of neuronal acetylcholine receptor genes in vertebrate skeletal muscle during development. J. Neurosci. 15, 1372-1383.
15. Cunningham J. M., Lennon V. A., Lambert E. H., and Scheithauer B. (1985) Acetylcholine receptors in small cell carcinomas. J. Neurochem. 45, 159-167.
16. Drachman D. B. (1994) Myasthenia gravis. N. Engl. J. Med. 330, 1797-1810.
17. Elgoyhen A. B., Johnson D. S., Boulter J., Vetter D. E., and Heinemann S. (1994) A9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. Cell 79, 705-715.
18. Fujita J., Yamadori I., Yamaji Y., Yamagishi Y., Takigawa K., and Takahara J. (1994) Myasthenia gravis associated with small-cell carcinoma of the lung. Chest 105, 624-625.
19. Gerzanich V., Anand R., and Lindstrom J. ( 1994) Homomers of α8 and α7 subunits of nicotinic receptors exhibit similar channel but contrasting binding site properties. Mol. Biol. 45, 212-220.
20. Gotti C., Briscini L., Verderio C., Oortigiesen M., Balestra B., and Clementi F. (1995) Native nicotinic acetylcholine receptors in human IMR-32 neuroblastoma cells: functional, immunological and pharmacological properties. Eur. J. Neurosci. 7, 2083-2092.
21. Griesmann G. E. and Lennon V. A. (1997) Detection of autoantibodies in myasthenia gravis and Lambert-Eaton myasthenic syndrome, in Manual of Clinical and Laboratory Immunology, 5th edit. (Rose N. R., de Macario E. C., Folds J. D., Lane H. C., and Nakamura R. M., eds), pp. 983-988. ASM Press, Washington, D.C.
22. Griesmann G. E., Sciamanna M. A., Wieben E. D., and Lennon V. A. (1994) Muscle-type nicotinic acetylcholine receptors (AChR) expressed aberrantly in small cell lung carcinoma (SCLC) of a patient with myasthenia gravis. (Abstr.) Muscle Nerve Suppl. 1, S185.
23. 2+ indicators with greatly improved luorescence properties. J. Biol. Chem. 260, 3440-3450.
24. Gu Y., Forsayeth J. R., Verrall S., Yu X. M., and Hall Z. W. (1991) Assembly of the mammalian muscle acetylcholine receptor m transfected COS cells. J. Cell Biol. 114, 799-807.
25. Lennon V. A. (1994a) Paraneoplastic autoantibodies: the case for a descriptive generic nomenclature. Neurology 44, 2236-2240.
26. Lennon V. A. (19946) The case for a descriptive generic nomenclature: clarification of immunostaining criteria for PCA-1, ANNA-1 and ANNA-2 autoantibodies. Neurology 44, 2412-2415.
27. Lennon V. A. and Lambert E. H. (1980) Myasthenia gravis induced by monoclonal antibodies to acetylcholine receptors. Nature 285, 238-240.
28. Lennon V. A., Kryzer T. J., Griesmann G. E., O'Suilleabhain P. E., Windebank A. J., Woppmann A., Miljanich G. P., and Lambert E.H. (1995) Calcium-channel antibodies in Lambert-Eaton myasthenic syndrome and other paraneoplastic syndromes. N. Engl. J. Med. 332, 1467-1474.
29. Lindstrom J. M., Lennon V. A., Seybold M. E., and Whittingham S. (1976) Experimental autoimmune myasthenia gravis and myasthenia gravis: biochemical and immunochemical aspects. Ann. NY Acad. Sci. 274, 254-274.
30. Lindstrom J. M., Schoepfer R., and Whiting P. (1987) Molecular studies of neuronal nicotinic acetylcholine receptor family. Mol. Neurobiol. 1, 281-337.
31. Lindstrom J., Anand R., Peng X., Gerzanich V., Wang F., and Li Y. (1995) Neuronal nicotinic receptor subtypes. Ann. NY Acad. Sci. 757, 100-116.
32. Lukas R. J. (1993) Expression of ganglia-type nicotinic acetylcholine receptors and nicotinic ligand binding sites by cells of the IMR-32 human neuroblastoma clonal line. J. Pharmacol. Exp. Ther. 265, 294-302.
33. Momoi M. and Lennon V. A. (1982) Purification and biochemical characterization of nicotinic acetylcholine receptors of human muscle. J. Biol. Chem. 257, 12757-12764.
34. Monteggia L. M., Gopalakrishnan M., and Giordano T. (1994) Molecular regulation of human α7 nAChR gene expression. Soc. Neurosci. Abstr. 20, 1131.
35. Oguro-Okano M., Griesmann G. E., Wieben E. D., Slaymaker S., Snutch T. P., and Lennon V. A. (1992) Molecular diversity of neuronal type calcium channels identified in small cell lung carcinoma. Mayo Clin. Proc. 67, 1150-1159.
36. Peng X., Katz M., Gerzanich V., Anand R., and Lindstrom J. (1994) Human α7 acetylcholine receptor: cloning of the α7 subumt from the SH-SY5Y cell line and determination of pharmacological properties of native receptors and functional α7 homomers expressed in Xenopus oocytes. Mol. Pharmacol. 45, 546-554.
37. Pugh P. C., Corriveau R. A., and Berg D. K. (1994) A subpopulation of neuronal ACh receptors among those binding. Soc. Neurosci. Abstr. 20, 1129.
38. Quik M., Chan J., and Patrick J. (1994) Alpha-bungarotoxin blocks the nicotinic receptor mediated increase in cell number in a neuroendocrine cell line. Brain Res. 655, 161-167.
39. 7 : a nicotinic cation channel highly permeable to calcium. J. Neurosci. 13, 596-604.
40. Sine S. M. (1988) Functional properties of human skeletal muscle acetylcholine receptors expressed by the TE671 cell line. J. Biol. Chem. 263, 18052-18062.
41. Smith M. M., Lindstrom J., and Merlie J. P. (1987) Formation of the α-bungarotoxin binding site and assembly of the nicotinic acetylcholine receptor subunits occur in the endoplasmic reticulum. J. Biol. Chem. 262, 4367-4376.
42. Sumikawa K. and Nishizaki T. (1994) The amino acid residues 1-128 in the a subunit of the nicotinic acetylcholine receptor contain assembly signals. Mol. Brain Res. 25, 257-264.
43. Tarroni P , Rubboli F., Chini B., Zwart R., Oortigiesen M., Sher E., and Clementi F. (1992) Neuronal-type nicotinic receptors in human neuroblastoma and small-cell lung carcinoma cell lines. FEBS Lett. 312, 66-70.
44. Tumilowicz J. J., Nichols W. W., Cholon J. J., and Greene A. E. (1970) Definition of a continuous human cell line derived from neuroblastoma. Cancer Res. 30, 2110-2118.
45. Tzartos S. J., Seybold M. E., and Lindstrom J. M. (1982) Specificities of antibodies to acetylcholine receptors in sera from myasthenia gravis patients measured by monoclonal antibodies. Proc. Natl. Acad. Sci. USA 79, 188-192.
46. Ullian E. M. and Sargent P. B. (1995) Pronounced cellular diversity and extrasynaptic location of nicotinic acetylcholine receptor subunit immunoreactivities in the chicken pretectum. J. Neurosci. 15, 7012-7023.
47. Viallet J. and Ihde D. C. (1991) Small cell carcinoma of the lung: clinical and biologic aspects. Clin. Rev. Oncol. Hematol. 11, 109-135.
48. 2+. Neuron 8, 353-362.
49. 3 muscarinic acetylcholine receptors inhibits voltage-dependent calcium influx in small cell lung carcinoma. J. Biol. Chem. 265, 1443-1447.
50. Williams C. L. and Lennon V. A. (1991) Activation of muscarmic acetylcholine receptors inhibits cell cycle progression of small cell lung carcinoma. Mol. Biol. Cell 2, 373-382.