B-Ring-modified and/or 5-demethylated nobiletin congeners: Inhibitory activity against pro-MMP-9 production

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 23, 2011, Pages 7085-7092

  Oshitari, Tetsuta ^a   Okuyama, Yuji ^a   Miyata, Yoshiki ^a   Kosano, Hiroshi ^a   Takahashi, Hideyo ^a   Natsugari, Hideaki ^a  

^a TEIKYO UNIVERSITY   (Japan)

Author keywords

Cataract; Demethylation; Matrix metalloproteinase 9; Nobiletin; Polymethoxyflavone

Indexed keywords

2',5,6,7,8 PENTAMETHOXYFLAVONE; 3' HYDROXY 5,6,7,8 TETRAMETHOXYFLAVONE; 3',5' DIHYDROXY 5,6,7,8 TETRAMETHOXYFLAVONE; 3',5,5',6,7,8 HEXAMETHOXYFLAVONE; 3',5,6,7,8 PENTAMETHOXYFLAVONE; 4' BENYLOXY 5 HYDROXY 3',6,7,8 TETRAMETHOXYFLAVONE; 4' HYDROXY 5,6,7,8 TETRAMETHOXYFLAVONE; 4',5 DIHYDROXY 3',6,7,8 TETRAMETHOXYFLAVONE; 5 HYDROXY 3',4',6,7,8 PENTAMETHOXYFLAVONE; FLAVONE DERIVATIVE; GARDENIN D; GELATINASE B; NOBILETIN; NOBILETIN DERIVATIVE; PHORBOL 13 ACETATE 12 MYRISTATE; TANGERETIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; XANTHOMICROL;

ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; LENS EPITHELIUM; STRUCTURE ACTIVITY RELATION;

CELL LINE; ENZYME PRECURSORS; EPITHELIAL CELLS; FLAVONES; HUMANS; LENS, CRYSTALLINE; MATRIX METALLOPROTEINASE 9; PROTEASE INHIBITORS; TETRADECANOYLPHORBOL ACETATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80655136947     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.10.001     Document Type: Article

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