The SHP-1 protein tyrosine phosphatase negatively modulates Akt signaling in the ghrelin/GHSR1a system

Molecular Biology of the Cell

Volumn 22, Issue 21, 2011, Pages 4182-4191

  Lodeiro, Maria ^a,b   Alén, Begoña O ^a,b   Mosteiro, Carlos S ^a,b   Beiroa, Daniel ^b,c   Nogueiras, Rubén ^b,c   Theodoropoulou, Marily ^d   Pardo, María ^a,b   Gallego, Rosalía ^c   Pazos, Yolanda ^a,b   Casanueva, Felipe F ^a,b,c   Camiña, Jesus P ^a,b  

^a Santiago University Clinical Hospital   (Spain)

^b Instituto de Salud Carlos III   (Spain)

^c UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^d MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN; GHRELIN; GHRELIN RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; PROTEIN P85; PROTEIN TYROSINE PHOSPHATASE SHP 1; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HORMONE SENSITIVITY; IN VITRO STUDY; LIPID DIET; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROADIPOCYTE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

3T3-L1 CELLS; ANIMALS; ARRESTINS; DIET, HIGH-FAT; ENZYME ASSAYS; GHRELIN; HEK293 CELLS; HUMANS; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, GHRELIN; SIGNAL TRANSDUCTION; SUBCUTANEOUS FAT; TISSUE CULTURE TECHNIQUES;

MUS;

EID: 80655128117     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E11-04-0373     Document Type: Article

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