High fat diet induced downregulation of microRNA-467b increased lipoprotein lipase in hepatic steatosis

Biochemical and Biophysical Research Communications

Volumn 414, Issue 4, 2011, Pages 664-669

  Ahn, Jiyun ^a   Lee, Hyunjung ^a   Chung, Chang Hwa ^a   Ha, Taeyoul ^a  

^a Korea Food Research Institute   (South Korea)

Author keywords

Insulin resistance; Lipoprotein lipase; MicroRNA 467b; Non alcoholic fatty liver disease; Steatosis

Indexed keywords

LIPOPROTEIN LIPASE; MICRORNA; MICRORNA 467B; SATURATED FATTY ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE CONTROL; DOWN REGULATION; FATTY LIVER; INSULIN RESISTANCE; LIPID DIET; LIVER; LIVER CELL; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; DIET, HIGH-FAT; DOWN-REGULATION; FATTY LIVER; LIPOPROTEIN LIPASE; MALE; MICE; MICE, INBRED C57BL; MICRORNAS;

MUS;

EID: 80555150535     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.09.120     Document Type: Article

References (41)

1. Gholam P.M., Flancbaum L., Machan J.T., Charney D.A., Kotler D.P. Non-alcoholic fatty liver disease in severely obese subjects. Am. J. Gastroenterol. 2007, 102:399-408.
2. Youssef W.I., McCullough A.J. Steatohepatitis in obese individuals. Best Pract. Res. Clin. Gastroenterol. 2002, 16:733-747.
3. Feldstein A.E., Canbay A., Guicciardi M.E., Higuchi H., Bronk S.F., Gores G.J. Diet associated hepatic steatosis sensitizes to Fas mediated liver injury in mice. J. Hepatol. 2003, 39:978-983.
4. Marchesini G., Brizi M., Morselli-Labate A.M., Bianchi G., Bugianesi E., McCullough A.J., Forlani G., Melchionda N. Association of non-alcoholic fatty liver disease with insulin resistance. Am. J. Med. 1999, 107:450-455.
5. Griffin M.E., Marcucci M.J., Cline G.W., Bell K., Barucci N., Lee D., Goodyear L.J., Kraegen E.W., White M.F., Shulman G.I. Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. Diabetes 1999, 48:1270-1274.
6. Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
7. Karp X., Ambros V. Developmental biology. Encountering microRNAs in cell fate signaling. Science 2005, 310:1288-1289.
8. Kahai S., Lee S.C., Lee D.Y., Yang J., Li M., Wang C.H., Jiang Z., Zhang Y., Peng C., Yang B.B. MicroRNA miR-378 regulates nephronectin expression modulating osteoblast differentiation by targeting GalNT-7. PLoS One 2009, 4:e7535.
9. Nilsen T.W. Mechanisms of microRNA-mediated gene regulation in animal cells. Trends Genet. 2007, 23:243-249.
10. Kim J., Krichevsky A., Grad Y., Hayes G.D., Kosik K.S., Church G.M., Ruvkun G. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. Proc. Natl. Acad. Sci. USA 2004, 101:360-365.
11. Lim L.P., Lau N.C., Garrett-Engele P., Grimson A., Schelter J.M., Castle J., Bartel D.P., Linsley P.S., Johnson J.M. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005, 433:769-773.
12. Wienholds E., Plasterk R.H. MicroRNA function in animal development. FEBS Lett. 2005, 579:5911-5922.
13. Xu P., Vernooy S.Y., Guo M., Hay B.A. The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism. Curr. Biol. 2003, 13:790-795.
14. Takanabe R., Ono K., Abe Y., Takaya T., Horie T., Wada H., Kita T., Satoh N., Shimatsu A., Hasegawa K. Up-regulated expression of microRNA-143 in association with obesity in adipose tissue of mice fed high-fat diet. Biochem. Biophys. Res. Commun. 2008, 376:728-732.
15. Lin Q., Gao Z., Alarcon R.M., Ye J., Yun Z. A role of miR-27 in the regulation of adipogenesis. FEBS J. 2009, 276:2348-2358.
16. Dolganiuc A., Petrasek J., Kodys K., Catalano D., Mandrekar P., Velayudham A., Szabo G. MicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced non-alcoholic steatohepatitis models in mice. Alcohol Clin. Exp. Res. 2009, 33:1704-1710.
17. Wang B., Majumder S., Nuovo G., Kutay H., Volinia S., Patel T., Schmittgen T.D., Croce C., Ghoshal K., Jacob S.T. Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice. Hepatology 2009, 50:1152-1161.
18. Korn E.D. Clearing factor, a heparin-activated lipoprotein lipase. I. Isolation and characterization of the enzyme from normal rat heart. J. Biol. Chem. 1955, 215:1-14.
19. Pardina E., Baena-Fustegueras J.A., Llamas R., Catalan R., Galard R., Lecube A., Fort J.M., Llobera M., Allende H., Vargas V., Peinado-Onsurbe J. Lipoprotein lipase expression in livers of morbidly obese patients could be responsible for liver steatosis. Obes. Surg. 2009, 19:608-616.
20. Chiu H.K., Qian K., Ogimoto K., Morton G.J., Wisse B.E., Agrawal N., McDonald T.O., Schwartz M.W., Dichek H.L. Mice lacking hepatic lipase are lean and protected against diet-induced obesity and hepatic steatosis. Endocrinology 2010, 151:993-1001.
21. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987, 162:156-159.
22. Okamoto Y., Tanaka S., Haga Y. Enhanced GLUT2 gene expression in an oleic acid-induced in vitro fatty liver model. Hepatol. Res. 2002, 23:138-144.
23. Feldstein A.E., Werneburg N.W., Canbay A., Guicciardi M.E., Bronk S.F., Rydzewski R., Burgart L.J., Gores G.J. Free fatty acids promote hepatic lipotoxicity by stimulating TNF-alpha expression via a lysosomal pathway. Hepatology 2004, 40:185-194.
24. Greenspan P., Mayer E.P., Fowler S.D. Nile red: a selective fluorescent stain for intracellular lipid droplets. J. Cell. Biol. 1985, 100:965-973.
25. Newberry E.P., Xie Y., Kennedy S.M., Luo J., Davidson N.O. Protection against Western diet-induced obesity and hepatic steatosis in liver fatty acid-binding protein knockout mice. Hepatology 2006, 44:1191-1205.
26. Qureshi K., Abrams G.A. Metabolic liver disease of obesity and role of adipose tissue in the pathogenesis of non-alcoholic fatty liver disease. World J. Gastroenterol. 2007, 13:3540-3553.
27. Chang C.L., Seo T., Matsuzaki M., Worgall T.S., Deckelbaum R.J. n-3 Fatty acids reduce arterial LDL-cholesterol delivery and arterial lipoprotein lipase levels and lipase distribution. Arterioscler. Thromb. Vasc. Biol. 2009, 29:555-561.
28. Mothe I., Van Obberghen E. Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action. J. Biol. Chem. 1996, 271:11222-11227.
29. Chitturi S., Farrell G.C., Hashimoto E., Saibara T., Lau G.K., Sollano J.D. Non-alcoholic fatty liver disease in the Asia-Pacific region: definitions and overview of proposed guidelines. J. Gastroenterol. Hepatol. 2007, 22:778-787.
30. Musso G., Gambino R., Cassader M. Emerging molecular targets for the treatment of non-alcoholic fatty liver disease. Annu. Rev. Med. 2010, 61:375-392.
31. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
32. Krutzfeldt J., Stoffel M. MicroRNAs: a new class of regulatory genes affecting metabolism. Cell Metab. 2006, 4:9-12.
33. Eckel R.H. Lipoprotein lipase. A multifunctional enzyme relevant to common metabolic diseases. N. Engl. J. Med. 1989, 320:1060-1068.
34. Carr M.C., Hokanson J.E., Deeb S.S., Purnell J.Q., Mitchell E.S., Brunzell J.D. A hepatic lipase gene promoter polymorphism attenuates the increase in hepatic lipase activity with increasing intra-abdominal fat in women. Arterioscler. Thromb. Vasc. Biol. 1999, 19:2701-2707.
35. Purnell J.Q., Kahn S.E., Albers J.J., Nevin D.N., Brunzell J.D., Schwartz R.S. Effect of weight loss with reduction of intra-abdominal fat on lipid metabolism in older men. Clin. Endocrinol. Metab. 2000, 85:977-982.
36. Kim J.K., Fillmore J.J., Chen Y., Yu C., Moore I.K., Pypaert M., Lutz E.P., Kako Y., Velez-Carrasco W., Goldberg I.J., Breslow J.L., Shulman G.I. Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance. Proc. Natl. Acad. Sci. USA 2001, 98:7522-7527.
37. Zambon A., Brown B.G., Deeb S.S., Brunzell J.D. Hepatic lipase as a focal point for the development and treatment of coronary artery disease. J. Investig. Med. 2001, 49:112-118.
38. Grundy S.M., Brewer H.B., Cleeman J.I., Smith S.C., Lenfant C. Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation 2004, 109:433-438.
39. Boden G. Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 1997, 46:3-10.
40. Khan A.H., Pessin J.E. Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways. Diabetologia 2002, 45:1475-1483.
41. Wang Q., Somwar R., Bilan P.J., Liu Z., Jin J., Woodgett J.R., Klip A. Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts. Mol. Cell Biol. 1999, 19:4008-4018.