Intranasal administration of adeno-associated virus type 12 (AAV12) leads to transduction of the nasal epithelia and can initiate transgene-specific immune response

Molecular Therapy

Volumn 19, Issue 11, 2011, Pages 1990-1998

  Quinn, Kathrina ^a   Quirion, Mary R ^b   Lo, Chia Yun ^b   Misplon, Julia A ^b   Epstein, Suzanne L ^b   Chiorini, John A ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INFLUENZA VACCINE; LUCIFERASE; NEUTRALIZING ANTIBODY; PARVOVIRUS VECTOR; VIRUS ANTIBODY; VIRUS NUCLEOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOMEGALOVIRUS; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG MEGADOSE; GENE EXPRESSION; GENETIC IMMUNIZATION; IMMUNE RESPONSE; IN VIVO STUDY; INFLUENZA A; INFLUENZA VIRUS A; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; NOSE MUCOSA; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRUS IMMUNITY;

ADENO-ASSOCIATED VIRUS; CYTOMEGALOVIRUS;

EID: 80455164638     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2011.146     Document Type: Article

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