메뉴 건너뛰기




Volumn 26, Issue 17, 2008, Pages 2062-2072

Comparison of vaccines for induction of heterosubtypic immunity to influenza A virus: Cold-adapted vaccine versus DNA prime-adenovirus boost strategies

Author keywords

Heterosubtypic immunity; Influenza; Pandemic

Indexed keywords

ADENOVIRUS VECTOR; DNA VACCINE; INFLUENZA VACCINE; NUCLEOPROTEIN; PROTEIN; SERYLLEUCYLLEUCYLTHREONYLGLUTAMYLVALYLGLUTAMYLTHREONYLPROLYLISOLEUCYL ARGINYLASPARAGINYLGLUTAMYLTRYPTOPHYLGLYCYLCYSTEINYLARGINYLCYSTEINYLASPAR AGINYLGLYCYLSERYLSERYLASPARTIC ACID; THREONYLTYROSYLGLUTAMINYLARGINYLTHREONYLARGINYLALANYLLEUCYLVALINE; UNCLASSIFIED DRUG; VIRUS ANTIBODY;

EID: 41649119921     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.02.047     Document Type: Article
Times cited : (73)

References (43)
  • 1
    • 78651171439 scopus 로고
    • Induction of partial specific heterotypic immunity in mice by a single infection with influenza A virus
    • Schulman J.L., and Kilbourne E.D. Induction of partial specific heterotypic immunity in mice by a single infection with influenza A virus. J Bacteriol 89 (1965) 170-174
    • (1965) J Bacteriol , vol.89 , pp. 170-174
    • Schulman, J.L.1    Kilbourne, E.D.2
  • 2
    • 0018950287 scopus 로고
    • Outcome of influenza infection: effect of site of initial infection and heterotypic immunity
    • Yetter R.A., Lehrer S., Ramphal R., and Small Jr. P.A. Outcome of influenza infection: effect of site of initial infection and heterotypic immunity. Infect Immun 29 (1980) 654-662
    • (1980) Infect Immun , vol.29 , pp. 654-662
    • Yetter, R.A.1    Lehrer, S.2    Ramphal, R.3    Small Jr., P.A.4
  • 3
    • 0028229934 scopus 로고
    • Heterosubtypic immunity to influenza type A virus in mice: effector mechanisms and their longevity
    • Liang S., Mozdzanowska K., Palladino G., and Gerhard W. Heterosubtypic immunity to influenza type A virus in mice: effector mechanisms and their longevity. J Immunol 152 (1994) 1653-1661
    • (1994) J Immunol , vol.152 , pp. 1653-1661
    • Liang, S.1    Mozdzanowska, K.2    Palladino, G.3    Gerhard, W.4
  • 4
    • 3042823259 scopus 로고    scopus 로고
    • Control of influenza virus infection by immunity to conserved viral features
    • Epstein S.L. Control of influenza virus infection by immunity to conserved viral features. Expert Rev Anti-Infect Ther 1 4 (2003) 627-638
    • (2003) Expert Rev Anti-Infect Ther , vol.1 , Issue.4 , pp. 627-638
    • Epstein, S.L.1
  • 5
    • 0018861995 scopus 로고
    • Cross-protection and cross-reactive cytotoxic T cells induced by influenza virus vaccines in mice
    • Webster R.G., and Askonas B.A. Cross-protection and cross-reactive cytotoxic T cells induced by influenza virus vaccines in mice. Eur J Immunol 10 (1980) 396-401
    • (1980) Eur J Immunol , vol.10 , pp. 396-401
    • Webster, R.G.1    Askonas, B.A.2
  • 6
    • 0035987429 scopus 로고    scopus 로고
    • Principles underlying the development and use of live attenuated cold-adapted influenza A and B virus vaccines
    • Murphy B.R., and Coelingh K. Principles underlying the development and use of live attenuated cold-adapted influenza A and B virus vaccines. Vir Immunol 15 2 (2002) 295-323
    • (2002) Vir Immunol , vol.15 , Issue.2 , pp. 295-323
    • Murphy, B.R.1    Coelingh, K.2
  • 7
    • 0020075394 scopus 로고
    • Evaluation of live and inactivated influenza-A virus-vaccines in a mouse model
    • Armerding D., Rossiter H., Ghazzouli I., and Liehl E. Evaluation of live and inactivated influenza-A virus-vaccines in a mouse model. J Infect Dis 145 3 (1982) 320-330
    • (1982) J Infect Dis , vol.145 , Issue.3 , pp. 320-330
    • Armerding, D.1    Rossiter, H.2    Ghazzouli, I.3    Liehl, E.4
  • 8
    • 0021325943 scopus 로고
    • Relative immunogenicity of the cold-adapted influenza virus A/Ann Arbor/6/60 (A/AA/6/60-ca), recombinants of A/AA/6/60-ca, and parental strains with similar surface antigens
    • Tannock G.A., Paul J.A., and Barry R.D. Relative immunogenicity of the cold-adapted influenza virus A/Ann Arbor/6/60 (A/AA/6/60-ca), recombinants of A/AA/6/60-ca, and parental strains with similar surface antigens. Infect Immun 43 2 (1984) 457-462
    • (1984) Infect Immun , vol.43 , Issue.2 , pp. 457-462
    • Tannock, G.A.1    Paul, J.A.2    Barry, R.D.3
  • 9
    • 0023193165 scopus 로고
    • Homotypic and heterotypic immunity of influenza A viruses induced by recombinants of the cold-adapted master strain A/Ann Arbor/6/60-ca
    • Tannock G.A., and Paul J.A. Homotypic and heterotypic immunity of influenza A viruses induced by recombinants of the cold-adapted master strain A/Ann Arbor/6/60-ca. Arch Virol 92 1/2 (1987) 121-133
    • (1987) Arch Virol , vol.92 , Issue.1-2 , pp. 121-133
    • Tannock, G.A.1    Paul, J.A.2
  • 10
    • 0019962489 scopus 로고
    • Humoral and cellular-responses of mice to infection with a cold-adapted influenza A virus variant
    • Mak N.K., Zhang Y.H., Ada G.L., and Tannock G.A. Humoral and cellular-responses of mice to infection with a cold-adapted influenza A virus variant. Infect Immun 38 1 (1982) 218-225
    • (1982) Infect Immun , vol.38 , Issue.1 , pp. 218-225
    • Mak, N.K.1    Zhang, Y.H.2    Ada, G.L.3    Tannock, G.A.4
  • 11
    • 0034897815 scopus 로고    scopus 로고
    • Immunogenic and isotype-specific responses to Russian and US cold-adapted influenza A vaccine donor strains A/Leningrad/134/17/57, A/Leningrad/134/47/57, and A/Ann Arbor/6/60 (H2N2) in mice
    • Wareing M.D., Watson J.M., Brooks M.J., and Tannock G.A. Immunogenic and isotype-specific responses to Russian and US cold-adapted influenza A vaccine donor strains A/Leningrad/134/17/57, A/Leningrad/134/47/57, and A/Ann Arbor/6/60 (H2N2) in mice. J Med Virol 65 1 (2001) 171-177
    • (2001) J Med Virol , vol.65 , Issue.1 , pp. 171-177
    • Wareing, M.D.1    Watson, J.M.2    Brooks, M.J.3    Tannock, G.A.4
  • 12
    • 0038544035 scopus 로고    scopus 로고
    • Route of administration is the prime determinant of IgA and IgG2a responses in the respiratory tract of mice to the cold-adapted live attenuated influenza A donor strain A/Leningrad/134/17/57
    • Wareing M.D., and Tannock G.A. Route of administration is the prime determinant of IgA and IgG2a responses in the respiratory tract of mice to the cold-adapted live attenuated influenza A donor strain A/Leningrad/134/17/57. Vaccine 21 23 (2003) 3097-3100
    • (2003) Vaccine , vol.21 , Issue.23 , pp. 3097-3100
    • Wareing, M.D.1    Tannock, G.A.2
  • 13
    • 20444426153 scopus 로고    scopus 로고
    • + cytokine responses in mice reveal differences in the relative immunogenicity of cold-adapted influenza-A vaccine donor strains
    • + cytokine responses in mice reveal differences in the relative immunogenicity of cold-adapted influenza-A vaccine donor strains. Vaccine 23 31 (2005) 4075-4081
    • (2005) Vaccine , vol.23 , Issue.31 , pp. 4075-4081
    • Wareing, M.D.1    Harrison, L.C.2    Tannock, G.A.3
  • 14
    • 33846219152 scopus 로고    scopus 로고
    • Priming with cold-adapted influenza A does not prevent infection but elicits long-lived protection against supralethal challenge with heterosubtypic virus
    • Powell T.J., Strutt T., Reome J., Hollenbaugh J.A., Roberts A.D., Woodland D.L., et al. Priming with cold-adapted influenza A does not prevent infection but elicits long-lived protection against supralethal challenge with heterosubtypic virus. J Immunol 178 2 (2007) 1030-1038
    • (2007) J Immunol , vol.178 , Issue.2 , pp. 1030-1038
    • Powell, T.J.1    Strutt, T.2    Reome, J.3    Hollenbaugh, J.A.4    Roberts, A.D.5    Woodland, D.L.6
  • 15
    • 0027411456 scopus 로고
    • Heterologous protection against influenza by injection of DNA encoding a viral protein
    • Ulmer J.B., Donnelly J.J., Parker S.E., Rhodes G.H., Felgner P.L., Dwarki V.J., et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259 (1993) 1745-1749
    • (1993) Science , vol.259 , pp. 1745-1749
    • Ulmer, J.B.1    Donnelly, J.J.2    Parker, S.E.3    Rhodes, G.H.4    Felgner, P.L.5    Dwarki, V.J.6
  • 17
    • 0036686714 scopus 로고    scopus 로고
    • DNA vaccine expressing conserved influenza virus proteins protective against H5N1 challenge infection in mice
    • Epstein S.L., Tumpey T.M., Misplon J.A., Lo C.-Y., Cooper L.A., Subbarao K., et al. DNA vaccine expressing conserved influenza virus proteins protective against H5N1 challenge infection in mice. Emerg Infect Dis 8 8 (2002) 796-801
    • (2002) Emerg Infect Dis , vol.8 , Issue.8 , pp. 796-801
    • Epstein, S.L.1    Tumpey, T.M.2    Misplon, J.A.3    Lo, C.-Y.4    Cooper, L.A.5    Subbarao, K.6
  • 18
    • 27644544183 scopus 로고    scopus 로고
    • Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein
    • Epstein S.L., Kong W.P., Misplon J.A., Lo C.-Y., Tumpey T.M., Xu L., et al. Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein. Vaccine 23 46/47 (2005) 5404-5410
    • (2005) Vaccine , vol.23 , Issue.46-47 , pp. 5404-5410
    • Epstein, S.L.1    Kong, W.P.2    Misplon, J.A.3    Lo, C.-Y.4    Tumpey, T.M.5    Xu, L.6
  • 19
    • 33847348999 scopus 로고    scopus 로고
    • Matrix protein 2 vaccination and protection against influenza viruses, including subtype H5N1
    • Tompkins S.M., Zhao Z.S., Lo C.-Y., Misplon J.A., Liu T., Ye Z.P., et al. Matrix protein 2 vaccination and protection against influenza viruses, including subtype H5N1. Emerg Infect Dis 13 3 (2007) 426-435
    • (2007) Emerg Infect Dis , vol.13 , Issue.3 , pp. 426-435
    • Tompkins, S.M.1    Zhao, Z.S.2    Lo, C.-Y.3    Misplon, J.A.4    Liu, T.5    Ye, Z.P.6
  • 20
    • 0023760366 scopus 로고
    • Induction, persistence and strain specificity of haemagglutinin-specific secretory antibodies in lungs of mice after intragastric administration of inactivated influenza virus vaccines
    • Chen K.-S., and Quinnan Jr. G.V. Induction, persistence and strain specificity of haemagglutinin-specific secretory antibodies in lungs of mice after intragastric administration of inactivated influenza virus vaccines. J Gen Virol 69 (1988) 2779-2784
    • (1988) J Gen Virol , vol.69 , pp. 2779-2784
    • Chen, K.-S.1    Quinnan Jr., G.V.2
  • 21
    • 0028107688 scopus 로고
    • The influenza-virus variant A/FM/1/47-MA possesses single amino-acid replacements in the hemagglutinin, controlling virulence, and in the matrix protein, controlling virulence as well as growth
    • Smeenk C.A., and Brown E.G. The influenza-virus variant A/FM/1/47-MA possesses single amino-acid replacements in the hemagglutinin, controlling virulence, and in the matrix protein, controlling virulence as well as growth. J Virol 68 1 (1994) 530-534
    • (1994) J Virol , vol.68 , Issue.1 , pp. 530-534
    • Smeenk, C.A.1    Brown, E.G.2
  • 22
    • 24644503497 scopus 로고    scopus 로고
    • Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals
    • Maines T.R., Lu X.H., Erb S.M., Edwards L., Guarner J., Greer P.W., et al. Avian influenza (H5N1) viruses isolated from humans in Asia in 2004 exhibit increased virulence in mammals. J Virol 79 18 (2005) 11788-11800
    • (2005) J Virol , vol.79 , Issue.18 , pp. 11788-11800
    • Maines, T.R.1    Lu, X.H.2    Erb, S.M.3    Edwards, L.4    Guarner, J.5    Greer, P.W.6
  • 23
    • 21644475386 scopus 로고    scopus 로고
    • A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates
    • Barouch D.H., Yang Z.Y., Kong W.P., Korioth-Schmitz B., Sumida S.M., Truitt D.M., et al. A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates. J Virol 79 14 (2005) 8828-8834
    • (2005) J Virol , vol.79 , Issue.14 , pp. 8828-8834
    • Barouch, D.H.1    Yang, Z.Y.2    Kong, W.P.3    Korioth-Schmitz, B.4    Sumida, S.M.5    Truitt, D.M.6
  • 24
    • 0035877213 scopus 로고    scopus 로고
    • Heterosubtypic immunity to influenza A virus in mice lacking either IgA, all Ig, NKT cells, or γδ T cells
    • Benton K.A., Misplon J.A., Lo C.-Y., Brutkiewicz R.R., Prasad S.A., and Epstein S.L. Heterosubtypic immunity to influenza A virus in mice lacking either IgA, all Ig, NKT cells, or γδ T cells. J Immunol 166 (2001) 7437-7445
    • (2001) J Immunol , vol.166 , pp. 7437-7445
    • Benton, K.A.1    Misplon, J.A.2    Lo, C.-Y.3    Brutkiewicz, R.R.4    Prasad, S.A.5    Epstein, S.L.6
  • 25
    • 0032874490 scopus 로고    scopus 로고
    • A universal influenza A vaccine based on the extracellular domain of the M2 protein
    • Neirynck S., Deroo T., Saelens X., Vanlandschoot P., Jou W.M., and Fiers W. A universal influenza A vaccine based on the extracellular domain of the M2 protein. Nat Med 5 10 (1999) 1157-1163
    • (1999) Nat Med , vol.5 , Issue.10 , pp. 1157-1163
    • Neirynck, S.1    Deroo, T.2    Saelens, X.3    Vanlandschoot, P.4    Jou, W.M.5    Fiers, W.6
  • 27
    • 33845497716 scopus 로고    scopus 로고
    • Prevention of antigenically drifted influenza by inactivated and live attenuated vaccines
    • Ohmit S.E., Victor J.C., Rotthoff J.R., Teich E.R., Truscon R.K., Baum L.L., et al. Prevention of antigenically drifted influenza by inactivated and live attenuated vaccines. N Engl J Med 355 24 (2006) 2513-2522
    • (2006) N Engl J Med , vol.355 , Issue.24 , pp. 2513-2522
    • Ohmit, S.E.1    Victor, J.C.2    Rotthoff, J.R.3    Teich, E.R.4    Truscon, R.K.5    Baum, L.L.6
  • 28
    • 0033913482 scopus 로고    scopus 로고
    • Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A/Sydney) not contained in the vaccine
    • Belshe R.B., Gruber W.C., Mendelman P.M., Cho I., Reisinger K., Block S.L., et al. Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A/Sydney) not contained in the vaccine. J Pediatr 136 2 (2000) 168-175
    • (2000) J Pediatr , vol.136 , Issue.2 , pp. 168-175
    • Belshe, R.B.1    Gruber, W.C.2    Mendelman, P.M.3    Cho, I.4    Reisinger, K.5    Block, S.L.6
  • 29
    • 35348960407 scopus 로고    scopus 로고
    • Vaxfectin™-formulated influenza DNA vaccines encoding NP and M2 viral proteins protect mice against lethal viral challenge
    • Jimenez G.S., Planchon R., Wei Q., Rusalov D., Geall A., Enas J., et al. Vaxfectin™-formulated influenza DNA vaccines encoding NP and M2 viral proteins protect mice against lethal viral challenge. Hum Vaccin 3 5 (2007) 157-164
    • (2007) Hum Vaccin , vol.3 , Issue.5 , pp. 157-164
    • Jimenez, G.S.1    Planchon, R.2    Wei, Q.3    Rusalov, D.4    Geall, A.5    Enas, J.6
  • 30
    • 0028821987 scopus 로고
    • Protection of mice against influenza A virus challenge by vaccination with baculovirus-expressed M2 protein
    • Slepushkin V.A., Katz J.M., Black R.A., Gamble W.C., Rota P.A., and Cox N.J. Protection of mice against influenza A virus challenge by vaccination with baculovirus-expressed M2 protein. Vaccine 13 15 (1995) 1399-1402
    • (1995) Vaccine , vol.13 , Issue.15 , pp. 1399-1402
    • Slepushkin, V.A.1    Katz, J.M.2    Black, R.A.3    Gamble, W.C.4    Rota, P.A.5    Cox, N.J.6
  • 31
    • 0033522471 scopus 로고    scopus 로고
    • Modified M2 proteins produce heterotypic immunity against influenza A virus
    • Frace A.M., Klimov A.I., Rowe T., Black R.A., and Katz J.M. Modified M2 proteins produce heterotypic immunity against influenza A virus. Vaccine 17 18 (1999) 2237-2244
    • (1999) Vaccine , vol.17 , Issue.18 , pp. 2237-2244
    • Frace, A.M.1    Klimov, A.I.2    Rowe, T.3    Black, R.A.4    Katz, J.M.5
  • 32
    • 0038402706 scopus 로고    scopus 로고
    • Induction of influenza type A virus-specific resistance by immunization of mice with a synthetic multiple antigenic peptide vaccine that contains ectodomains of matrix protein 2
    • Mozdzanowska K., Feng J.Q., Eid M., Kragol G., Cudic M., Otvos L., et al. Induction of influenza type A virus-specific resistance by immunization of mice with a synthetic multiple antigenic peptide vaccine that contains ectodomains of matrix protein 2. Vaccine 21 19/20 (2003) 2616-2626
    • (2003) Vaccine , vol.21 , Issue.19-20 , pp. 2616-2626
    • Mozdzanowska, K.1    Feng, J.Q.2    Eid, M.3    Kragol, G.4    Cudic, M.5    Otvos, L.6
  • 33
    • 33748993450 scopus 로고    scopus 로고
    • Live, attenuated influenza A H5N1 candidate vaccines provide broad cross-protection in mice and ferrets
    • Suguitan A.L., McAuliffe J., Mills K.L., Jin H., Duke G., Lu B., et al. Live, attenuated influenza A H5N1 candidate vaccines provide broad cross-protection in mice and ferrets. Plos Medicine 3 9 (2006) 1541-1555
    • (2006) Plos Medicine , vol.3 , Issue.9 , pp. 1541-1555
    • Suguitan, A.L.1    McAuliffe, J.2    Mills, K.L.3    Jin, H.4    Duke, G.5    Lu, B.6
  • 34
    • 33846260267 scopus 로고    scopus 로고
    • Cross-protective immunity in mice induced by live-attenuated or inactivated vaccines against highly pathogenic influenza A (H5N1) viruses
    • Lu X.H., Edwards L.E., Desheva J.A., Nguyen D.C., Rekstin A., Stephenson I., et al. Cross-protective immunity in mice induced by live-attenuated or inactivated vaccines against highly pathogenic influenza A (H5N1) viruses. Vaccine 24 44-46 (2006) 6588-6593
    • (2006) Vaccine , vol.24 , Issue.44-46 , pp. 6588-6593
    • Lu, X.H.1    Edwards, L.E.2    Desheva, J.A.3    Nguyen, D.C.4    Rekstin, A.5    Stephenson, I.6
  • 35
    • 33846240928 scopus 로고    scopus 로고
    • Characterization of an influenza A H5N2 reassortant as a candidate for live-attenuated and inactivated vaccines against highly pathogenic H5N1 viruses with pandemic potential
    • Desheva J.A., Lu X.H., Rekstin A.R., Rudenko L.G., Swayne D.E., Cox N.J., et al. Characterization of an influenza A H5N2 reassortant as a candidate for live-attenuated and inactivated vaccines against highly pathogenic H5N1 viruses with pandemic potential. Vaccine 24 47/48 (2006) 6859-6866
    • (2006) Vaccine , vol.24 , Issue.47-48 , pp. 6859-6866
    • Desheva, J.A.1    Lu, X.H.2    Rekstin, A.R.3    Rudenko, L.G.4    Swayne, D.E.5    Cox, N.J.6
  • 36
    • 0036213345 scopus 로고    scopus 로고
    • Origin and evolution of influenza virus hemagglutinin genes
    • Suzuki Y., and Nei M. Origin and evolution of influenza virus hemagglutinin genes. Mol Biol Evol 19 4 (2002) 501-509
    • (2002) Mol Biol Evol , vol.19 , Issue.4 , pp. 501-509
    • Suzuki, Y.1    Nei, M.2
  • 38
    • 0034823799 scopus 로고    scopus 로고
    • Development of formulations that enhance physical stability of viral vectors for gene therapy
    • Croyle M.A., Cheng X., and Wilson J.M. Development of formulations that enhance physical stability of viral vectors for gene therapy. Gene Therapy 8 17 (2001) 1281-1290
    • (2001) Gene Therapy , vol.8 , Issue.17 , pp. 1281-1290
    • Croyle, M.A.1    Cheng, X.2    Wilson, J.M.3
  • 39
    • 33845466958 scopus 로고    scopus 로고
    • Immunogenicity of heterologous recombinant adenovirus prime-boost vaccine regimens is enhanced by circumventing vector cross-reactivity
    • Thorner A.R., Lemckert A.A.C., Goudsmit J., Lynch D.M., Ewald B.A., Denholtz M., et al. Immunogenicity of heterologous recombinant adenovirus prime-boost vaccine regimens is enhanced by circumventing vector cross-reactivity. J Virol 80 24 (2006) 12009-12016
    • (2006) J Virol , vol.80 , Issue.24 , pp. 12009-12016
    • Thorner, A.R.1    Lemckert, A.A.C.2    Goudsmit, J.3    Lynch, D.M.4    Ewald, B.A.5    Denholtz, M.6
  • 40
    • 33646586362 scopus 로고    scopus 로고
    • Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity
    • Roberts D.M., Nanda A., Havenga M.J., Abbink P., Lynch D.M., Ewald B.A., et al. Hexon-chimaeric adenovirus serotype 5 vectors circumvent pre-existing anti-vector immunity. Nature 441 7090 (2006) 239-243
    • (2006) Nature , vol.441 , Issue.7090 , pp. 239-243
    • Roberts, D.M.1    Nanda, A.2    Havenga, M.J.3    Abbink, P.4    Lynch, D.M.5    Ewald, B.A.6
  • 41
    • 0041707861 scopus 로고    scopus 로고
    • Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines
    • Barouch D.H., McKay P.F., Sumida S.M., Santra S., Jackson S.S., Gorgone D.A., et al. Plasmid chemokines and colony-stimulating factors enhance the immunogenicity of DNA priming-viral vector boosting human immunodeficiency virus type 1 vaccines. J Virol 77 16 (2003) 8729-8735
    • (2003) J Virol , vol.77 , Issue.16 , pp. 8729-8735
    • Barouch, D.H.1    McKay, P.F.2    Sumida, S.M.3    Santra, S.4    Jackson, S.S.5    Gorgone, D.A.6
  • 42
    • 0025806949 scopus 로고
    • Human T cell recognition of influenza A nucleoprotein-specificity and genetic restriction of immunodominant T helper cell epitopes
    • Brett S.J., Blau J., Hughes-Jenkins C.M., Rhodes J., Liew F.Y., and Tite J.P. Human T cell recognition of influenza A nucleoprotein-specificity and genetic restriction of immunodominant T helper cell epitopes. J Immunol 147 3 (1991) 984-991
    • (1991) J Immunol , vol.147 , Issue.3 , pp. 984-991
    • Brett, S.J.1    Blau, J.2    Hughes-Jenkins, C.M.3    Rhodes, J.4    Liew, F.Y.5    Tite, J.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.