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Volumn 7, Issue 11, 2011, Pages 1325-1333

Antiangiogenic effects of zoledronate on cancer neovasculature

Author keywords

angiogenesis; cancer; neovasculature; zoledronate

Indexed keywords

AFLIBERCEPT; ALPHA INTERFERON; BETA INTERFERON; BEVACIZUMAB; DOCETAXEL; ENDOSTATIN; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GEMCITABINE; INTERLEUKIN 12; INTERLEUKIN 18; MARIMASTAT; MASPIN; NAVELBINE; PACLITAXEL; PREDNISONE; SORAFENIB; SUNITINIB; THALIDOMIDE; THROMBOSPONDIN 1; VANDETANIB; VASCULOTROPIN B; ZOLEDRONIC ACID;

EID: 80455158247     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.11.113     Document Type: Review
Times cited : (16)

References (68)
  • 1
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N. Engl. J. Med. 285(21), 1182-1186 (1971).
    • (1971) N. Engl. J. Med. , vol.285 , Issue.21 , pp. 1182-1186
    • Folkman, J.1
  • 2
    • 0029753768 scopus 로고    scopus 로고
    • Genetic instability induced by the tumor microenvironment
    • Reynolds TY, Rockwell S, Glazer PM. Genetic instability induced by the tumor microenvironment. Cancer Res. 56(24), 5754-5757 (1996). (Pubitemid 26422184)
    • (1996) Cancer Research , vol.56 , Issue.24 , pp. 5754-5757
    • Reynolds, T.Y.1    Rockwell, S.2    Glazer, P.M.3
  • 3
    • 79956328903 scopus 로고    scopus 로고
    • Molecular mechanisms and clinical applications of angiogenesis
    • Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature 473(7347), 298-307 (2011).
    • (2011) Nature , vol.473 , Issue.7347 , pp. 298-307
    • Carmeliet, P.1    Jain, R.K.2
  • 4
    • 65249166077 scopus 로고    scopus 로고
    • Phase I trial of sunitinib malate plus interferon a for patients with metastatic renal cell carcinoma
    • Motzer RJ, Hudes G, Wilding G et al. Phase I trial of sunitinib malate plus interferon a for patients with metastatic renal cell carcinoma. Clin. Genitourin. Cancer 7(1), 28-33 (2009).
    • (2009) Clin. Genitourin. Cancer , vol.7 , Issue.1 , pp. 28-33
    • Motzer, R.J.1    Hudes, G.2    Wilding, G.3
  • 5
    • 20544478429 scopus 로고    scopus 로고
    • Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastaticcolorectal cancer: Results of a randomized Phase II trial
    • Kabbinavar FF, Schulz J, McCleod M et al. Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastaticcolorectal cancer: results of a randomized Phase II trial. J. Clin. Oncol. 23(16), 3697-3705 (2005).
    • (2005) J. Clin. Oncol. , vol.23 , Issue.16 , pp. 3697-3705
    • Kabbinavar, F.F.1    Schulz, J.2    McCleod, M.3
  • 9
    • 0028202499 scopus 로고
    • Preclinical pharmacology of CGP 42'446, a new, potent, heterocyclic bisphosphonate compound
    • Green JR, Muller K, Jaeggi KA. Preclinical pharmacology of CGP 42'446, a new, potent, heterocyclic bisphosphonate compound. J. Bone Miner. Res. 9(5), 745-751 (1994). (Pubitemid 24130477)
    • (1994) Journal of Bone and Mineral Research , vol.9 , Issue.5 , pp. 745-751
    • Green, J.R.1    Muller, K.2    Jaeggi, K.A.3
  • 11
    • 0031754521 scopus 로고    scopus 로고
    • Heterocycle-containing bisphosphonates cause apoptosis and inhibit bone resorption by preventing protein prenylation: Evidence from structure- activity relationships in J774 macrophages
    • DOI 10.1359/jbmr.1998.13.11.1668
    • Luckman SP, Coxon FP, Ebetino FH, Russell RG, Rogers MJ. Heterocycle-containing bisphosphonates cause apoptosis and inhibit bone resorption by preventing protein prenylation: evidence from structure-activity relationships in J774 macrophages. J. Bone Miner. Res. 13(11), 1668-1678 (1998). (Pubitemid 28491995)
    • (1998) Journal of Bone and Mineral Research , vol.13 , Issue.11 , pp. 1668-1678
    • Luckman, S.P.1    Coxon, F.P.2    Ebetino, F.H.3    Russell, R.G.G.4    Rogers, M.J.5
  • 12
    • 33646725498 scopus 로고    scopus 로고
    • The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs
    • USA
    • Kavanagh KL, Guo K, Dunford JE et al. The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs. Proc. Natl Acad. Sci. USA 103(20), 7829-34 (2006).
    • (2006) Proc. Natl Acad. Sci. , vol.103 , Issue.20 , pp. 7829-34
    • Kavanagh, K.L.1    Guo, K.2    Dunford, J.E.3
  • 13
    • 0037029682 scopus 로고    scopus 로고
    • The bisphosphonate zoledronic acid impairs membrane localisation and induces cytochrome c release in breast cancer cells
    • DOI 10.1038/sj.bjc.6600297
    • Senaratne SG, Mansi JL, Colston KW. The bisphosphonate zoledronic acid impairs Ras membrane [correction of impairs membrane] localisation and induces cytochrome c release in breast cancer cells. Br. J. Cancer 86(9), 1479-86 (2002). (Pubitemid 34548073)
    • (2002) British Journal of Cancer , vol.86 , Issue.9 , pp. 1479-1486
    • Senaratne, S.G.1    Mansi, J.L.2    Colston, K.W.3
  • 17
    • 78650513866 scopus 로고    scopus 로고
    • Zoledronic acid induces cell-cycle prolongation in murine lung cancer cells by perturbing cyclin and Ras expression
    • Li YY, Chang JW, Liu YC et al. Zoledronic acid induces cell-cycle prolongation in murine lung cancer cells by perturbing cyclin and Ras expression. Anticancer Drugs 22(1), 89-98
    • Anticancer Drugs , vol.22 , Issue.1 , pp. 89-98
    • Li, Y.Y.1    Chang, J.W.2    Liu, Y.C.3
  • 19
    • 0036250129 scopus 로고    scopus 로고
    • Bisphosphonates inhibit stromelysin-1 (MMP-3), matrix metalloelastase (MMP-12), collagenase-3 (MMP-13) and enamelysin (MMP-20), but not urokinase-type plasminogen activator, and diminish invasion and migration of human malignant and endothelial cell lines
    • DOI 10.1097/00001813-200203000-00006
    • Heikkila P, Teronen O, Moilanen M et al. Bisphosphonates inhibit stromelysin 1 (MMP 3), matrix metalloelastase (MMP 12), collagenase 3 (MMP 13) and enamelysin (MMP 20), but not urokinase-type plasminogen activator, and diminish invasion and migration of human malignant and endothelial cell lines. Anticancer Drugs 13(3), 245-254 (2002). (Pubitemid 34492706)
    • (2002) Anti-Cancer Drugs , vol.13 , Issue.3 , pp. 245-254
    • Heikkila, P.1    Teronen, O.2    Moilanen, M.3    Konttinen, Y.T.4    Hanemaaijer, R.5    Laitinen, M.6    Maisi, P.7    Van Der Pluijm, G.8    Bartlett, J.D.9    Salo, T.10    Sorsa, T.11
  • 23
    • 33845529993 scopus 로고    scopus 로고
    • Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways
    • DOI 10.1111/j.1538-7836.2006.02259.x
    • Hasmim M, Bieler G, Ruegg C. Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways. J. Thromb. Haemost. 5(1), 166-173 (2007). (Pubitemid 44921082)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.1 , pp. 166-173
    • Hasmim, M.1    Bieler, G.2    Ruegg, C.3
  • 24
    • 77951587849 scopus 로고    scopus 로고
    • Microvascular endothelial cell responses in vitro and in vivo: Modulation by zoledronic acid and paclitaxel
    • Michailidou M, Brown HK, Lefley DV et al. Microvascular endothelial cell responses in vitro and in vivo: modulation by zoledronic acid and paclitaxel? J. Vasc. Res. 47(6), 481-493 (2010).
    • (2010) J. Vasc. Res. , vol.47 , Issue.6 , pp. 481-493
    • Michailidou, M.1    Brown, H.K.2    Lefley, D.V.3
  • 25
    • 0242353251 scopus 로고    scopus 로고
    • Zoledronate Sensitizes Endothelial Cells to Tumor Necrosis Factor-induced Programmed Cell Death: Evidence for the suppression of sustained activation of focal adhesion kinase and protein kinase B/Akt
    • DOI 10.1074/jbc.M308114200
    • Bezzi M, Hasmim M, Bieler G, Dormond O, Ruegg C. Zoledronate sensitizes endothelial cells to tumor necrosis factor-induced programmed cell death: evidence for the suppression of sustained activation of focal adhesion kinase and protein kinase B/Akt. J. Biol. Chem 278(44), 43603-43614 (2003). (Pubitemid 37345986)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.44 , pp. 43603-43614
    • Bezzi, M.1    Hasmim, M.2    Bieler, G.3    Dormond, O.4    Ruegg, C.5
  • 27
    • 77952388048 scopus 로고    scopus 로고
    • Accumulation of VEGFR2 in zoledronic acid-treated endothelial cells
    • Basi DL, Lee SW, Helfman S, Mariash A, Lunos SA. Accumulation of VEGFR2 in zoledronic acid-treated endothelial cells. Mol. Med. Report 3(3), 399-403 (2010).
    • (2010) Mol. Med. Report , vol.3 , Issue.3 , pp. 399-403
    • Basi, D.L.1    Lee, S.W.2    Helfman, S.3    Mariash, A.4    Lunos, S.A.5
  • 29
    • 57149098821 scopus 로고    scopus 로고
    • Anti-angiogenic property of zoledronic acid by inhibition of endothelial progenitor cell differentiation
    • Yamada J, Tsuno NH, Kitayama J et al. Anti-angiogenic property of zoledronic acid by inhibition of endothelial progenitor cell differentiation. J. Surg. Res. 151(1), 115-120 (2009).
    • (2009) J. Surg. Res. , vol.151 , Issue.1 , pp. 115-120
    • Yamada, J.1    Tsuno, N.H.2    Kitayama, J.3
  • 30
    • 78751648671 scopus 로고    scopus 로고
    • Bisphosphonates: Restrictions for vasculogenesis and angiogenesis: Inhibition of cell function of endothelial progenitor cells and mature endothelial cells in vitro
    • Ziebart T, Pabst A, Klein MO. Bisphosphonates: restrictions for vasculogenesis and angiogenesis: inhibition of cell function of endothelial progenitor cells and mature endothelial cells in vitro. Clin. Oral Investig. 15(1), 105-111 (2011).
    • (2011) Clin. Oral Investig. , vol.15 , Issue.1 , pp. 105-111
    • Ziebart, T.1    Pabst, A.2    Klein, M.O.3
  • 31
    • 0021282093 scopus 로고
    • Studies of inflammation and wound healing: Angiogenesis and collagen synthesis stimulated in vivo by resident and activated wound macrophages
    • Hunt TK, Knighton DR, Thakral KK, Goodson WH 3rd, Andrews WS. Studies on inflammation and wound healing: angiogenesis and collagen synthesis stimulated in vivo by resident and activated wound macrophages. Surgery 96(1), 48-54 (1984). (Pubitemid 14094943)
    • (1984) Surgery , vol.96 , Issue.1 , pp. 48-54
    • Hunt, T.K.1    Knighton, D.R.2    Thakral, K.K.3
  • 32
    • 0000391746 scopus 로고    scopus 로고
    • Matrix metalloproteinase 9 triggers the angiogenic switch during carcinogenesis
    • Bergers G, Brekken R, McMahon G et al. Matrix metalloproteinase 9 triggers the angiogenic switch during carcinogenesis. Nat. Cell Biol. 2(10), 737-744 (2000).
    • (2000) Nat. Cell Biol. , vol.2 , Issue.10 , pp. 737-744
    • Bergers, G.1    Brekken, R.2    McMahon, G.3
  • 33
    • 4944239035 scopus 로고    scopus 로고
    • An amino-bisphosphonate targets MMP-9 - Expressing macrophages and angiogenesis to impair cervical carcinogenesis
    • DOI 10.1172/JCI200422087
    • Giraudo E, Inoue M, Hanahan D. An amino-bisphosphonate targets MMP 9- expressing macrophages and angiogenesis to impair cervical carcinogenesis. J. Clin. Invest. 114(5), 623-633 (2004). (Pubitemid 39578752)
    • (2004) Journal of Clinical Investigation , vol.114 , Issue.5 , pp. 623-633
    • Giraudo, E.1    Inoue, M.2    Hanahan, D.3
  • 34
    • 39849100541 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells
    • DOI 10.1016/j.ccr.2007.11.032, PII S1535610808000020
    • Ahn GO, Brown JM. Matrix metalloproteinase 9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells. Cancer Cell 13(3), 193-205 (2008). (Pubitemid 351318369)
    • (2008) Cancer Cell , vol.13 , Issue.3 , pp. 193-205
    • Ahn, G.-O.1    Brown, J.M.2
  • 35
    • 0026320852 scopus 로고
    • Bisphosphonate action alendronate localization in rat bone and effects on osteoclast ultrastructure
    • Sato M, Grasser W, Endo N et al. Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure. J. Clin. Invest. 88(6), 2095-2105 (1991).
    • (1991) J. Clin. Invest. , vol.88 , Issue.6 , pp. 2095-2105
    • Sato, M.1    Grasser, W.2    Endo, N.3
  • 37
    • 37549048038 scopus 로고    scopus 로고
    • Zoledronic acid inhibits osteosarcoma growth in an orthotopic model
    • 12 Pt. 1
    • Dass CR, Choong PF. Zoledronic acid inhibits osteosarcoma growth in an orthotopic model. Mol. Cancer Ther. 6(12 Pt. 1), 3263-3270 (2007).
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 3263-3270
    • Dass, C.R.1    Choong, P.F.2
  • 39
    • 0031932783 scopus 로고    scopus 로고
    • In vitro cytoreductive effects on multiple myeloma cells induced by bisphosphonates
    • DOI 10.1038/sj.leu.2400892
    • Aparicio A, Gardner A, Tu Y, Savage A, Berenson J, Lichtenstein A. In vitro cytoreductive effects on multiple myeloma cells induced by bisphosphonates. Leukemia 12(2), 220-229 (1998). (Pubitemid 28108075)
    • (1998) Leukemia , vol.12 , Issue.2 , pp. 220-229
    • Aparicio, A.1    Gardner, A.2    Tu, Y.3    Savage, A.4    Berenson, J.5    Lichtenstein, A.6
  • 40
    • 45949099277 scopus 로고    scopus 로고
    • The bisphosphonate, zoledronic acid reduces experimental neuroblastoma growth by interfering with tumor angiogenesis
    • Backman U, Svensson A, Christofferson R, H, Azarbayjani F. The bisphosphonate, zoledronic acid reduces experimental neuroblastoma growth by interfering with tumor angiogenesis. Anticancer Res. 28(3A), 1551-1557 (2008). (Pubitemid 351892928)
    • (2008) Anticancer Research , vol.28 , Issue.3 A , pp. 1551-1557
    • Backman, U.1    Svensson, A.2    Christofferson, R.H.3    Azarbayjani, F.4
  • 42
    • 77953698788 scopus 로고    scopus 로고
    • Drug-induced vessel remodeling in bone metastases as assessed by dynamic contrast enhanced magnetic resonance imaging and vessel size imaging: A longitudinal in vivo study
    • Bauerle T, Merz M, Komljenovic D, Zwick S, Semmler W. Drug-induced vessel remodeling in bone metastases as assessed by dynamic contrast enhanced magnetic resonance imaging and vessel size imaging: a longitudinal in vivo study. Clin. Cancer Res. 16(12), 3215-3225 (2010).
    • (2010) Clin. Cancer Res. , vol.16 , Issue.12 , pp. 3215-3225
    • Bauerle, T.1    Merz, M.2    Komljenovic, D.3    Zwick, S.4    Semmler, W.5
  • 43
    • 77954229219 scopus 로고    scopus 로고
    • Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects
    • Zhang, W, Zhu XD, Sun HC et al. Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects. Clin. Cancer Res. 16(13), 3420-3430 (2010).
    • (2010) Clin. Cancer Res. , vol.16 , Issue.13 , pp. 3420-3430
    • Zhang, W.1    Zhu, X.D.2    Sun, H.C.3
  • 45
    • 3442901908 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice
    • DOI 10.1158/0008-5472.CAN-04-0961
    • Aharinejad S, Paulus P, Sioud M et al. Colony-stimulating factor 1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice. Cancer Res. 64(15), 5378-5384 (2004). (Pubitemid 39006559)
    • (2004) Cancer Research , vol.64 , Issue.15 , pp. 5378-5384
    • Aharinejad, S.1    Paulus, P.2    Sioud, M.3    Hofmann, M.4    Zins, K.5    Schafer, R.6    Stanley, E.R.7    Abraham, D.8
  • 46
    • 78651405675 scopus 로고    scopus 로고
    • PDGFR signaling blockade in marrow stroma impairs lung cancer bone metastasis
    • Catena R, Luis-Ravelo D, Anton I et al. PDGFR signaling blockade in marrow stroma impairs lung cancer bone metastasis. Cancer Res. 71(1), 164-174 (2011).
    • (2011) Cancer Res. , vol.71 , Issue.1 , pp. 164-174
    • Catena, R.1    Luis-Ravelo, D.2    Anton, I.3
  • 47
    • 0035917560 scopus 로고    scopus 로고
    • The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: Evidence for synergy with paclitaxel
    • DOI 10.1054/bjoc.2001.1727
    • Jagdev SP, Coleman RE, Shipman CM, Rostami HA, Croucher PI. The bisphosphonate, zoledronic acid, induces apoptosis of breast cancer cells: evidence for synergy with paclitaxel. Br. J. Cancer 84(8), 1126-1134 (2001). (Pubitemid 32448513)
    • (2001) British Journal of Cancer , vol.84 , Issue.8 , pp. 1126-1134
    • Jagdev, S.P.1    Coleman, R.E.2    Shipman, C.M.3    Rostami, H.A.4    Croucher, P.I.5
  • 48
    • 51049114468 scopus 로고    scopus 로고
    • Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer
    • Ottewell PD, Monkkonen H, Jones M, Lefley DV, Coleman RE, Holen I. Antitumor effects of doxorubicin followed by zoledronic acid in a mouse model of breast cancer. J. Natl Cancer Inst. 100(16), 1167-1178 (2008).
    • (2008) J. Natl Cancer Inst. , vol.100 , Issue.16 , pp. 1167-1178
    • Ottewell, P.D.1    Monkkonen, H.2    Jones, M.3    Lefley, D.V.4    Coleman, R.E.5    Holen, I.6
  • 49
    • 77954991297 scopus 로고    scopus 로고
    • Enhancing cytotoxic and apoptotic effect in OVCAR 3 and MDAH 2774 cells with all-trans retinoic acid and zoledronic acid: A paradigm of synergistic molecular targeting treatment for ovarian cancer
    • Karabulut B, Karaca B, Varol U et al. Enhancing cytotoxic and apoptotic effect in OVCAR 3 and MDAH 2774 cells with all-trans retinoic acid and zoledronic acid: a paradigm of synergistic molecular targeting treatment for ovarian cancer. J. Exp. Clin. Cancer Res. 29, 102 (2010).
    • (2010) J. Exp. Clin. Cancer Res. , vol.29 , pp. 102
    • Karabulut, B.1    Karaca, B.2    Varol, U.3
  • 50
    • 77957134474 scopus 로고    scopus 로고
    • Metronomic administration of zoledronic acid and taxotere combination in castration resistant prostate cancer patients: Phase I ZANTE trial
    • Facchini G, Caraglia M, Morabito A et al. Metronomic administration of zoledronic acid and taxotere combination in castration resistant prostate cancer patients: Phase I ZANTE trial. Cancer Biol Ther. 10(6), 543-548 (2010).
    • (2010) Cancer Biol Ther. , vol.10 , Issue.6 , pp. 543-548
    • Facchini, G.1    Caraglia, M.2    Morabito, A.3
  • 52
    • 33847228810 scopus 로고    scopus 로고
    • Phase II trial of gemcitabine prednisone and zoledronic acid in pretreated patients with hormone refractory prostate cancer
    • Di Lorenzo G, Autorino R, Giuliano M et al. Phase II trial of gemcitabine, prednisone, and zoledronic acid in pretreated patients with hormone refractory prostate cancer. Urology 69(2), 347-351 (2007).
    • (2007) Urology , vol.69 , Issue.2 , pp. 347-351
    • Di Lorenzo, G.1    Autorino, R.2    Giuliano, M.3
  • 53
    • 37549004818 scopus 로고    scopus 로고
    • Zoledronic acid affects over-angiogenic phenotype of endothelial cells in patients with multiple myeloma
    • 12 Pt. 1
    • Scavelli C, Di Pietro G, Cirulli T et al. Zoledronic acid affects over-angiogenic phenotype of endothelial cells in patients with multiple myeloma. Mol. Cancer Ther. 6(12 Pt. 1), 3256-3262 (2007).
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 3256-3262
    • Scavelli, C.1    Di Pietro, G.2    Cirulli, T.3
  • 54
    • 72449165023 scopus 로고    scopus 로고
    • Bortezomib and zoledronic acid on angiogenic and vasculogenic activities of bone marrow macrophages in patients with multiple myeloma
    • Moschetta M, Di Pietro G, Ria R et al. Bortezomib and zoledronic acid on angiogenic and vasculogenic activities of bone marrow macrophages in patients with multiple myeloma. Eur. J. Cancer 46(2), 420-429 (2010).
    • (2010) Eur. J. Cancer , vol.46 , Issue.2 , pp. 420-429
    • Moschetta, M.1    Di Pietro, G.2    Ria, R.3
  • 57
    • 0027097806 scopus 로고
    • Interleukin 8 as a macrophage-derived mediator of angiogenesis
    • Koch AE, Polverini PJ, Kunkel SL et al. Interleukin 8 as a macrophage-derived mediator of angiogenesis. Science 258(5089), 1798-1801 (1992).
    • (1992) Science , vol.258 , Issue.5089 , pp. 1798-1801
    • Koch, A.E.1    Polverini, P.J.2    Kunkel, S.L.3
  • 58
    • 36248984827 scopus 로고    scopus 로고
    • Serum IL 8 and IL 12 levels in breast cancer
    • Derin D, Soydinc HO, Guney N et al. Serum IL 8 and IL 12 levels in breast cancer. Med. Oncol. 24(2), 163-168 (2007).
    • (2007) Med. Oncol. , vol.24 , Issue.2 , pp. 163-168
    • Derin, D.1    Soydinc, H.O.2    Guney, N.3
  • 59
    • 78650820824 scopus 로고    scopus 로고
    • Significance of serum tumor necrosis factor a and its combination with HER 2 codon 655 polymorphism in the diagnosis and prognosis of breast cancer
    • Papadopoulou E, Tripsianis G, Anagnostopoulos K et al. Significance of serum tumor necrosis factor a and its combination with HER 2 codon 655 polymorphism in the diagnosis and prognosis of breast cancer. Int. J. Biol. Markers 25(3), 126-135 (2010).
    • (2010) Int. J. Biol. Markers , vol.25 , Issue.3 , pp. 126-135
    • Papadopoulou, E.1    Tripsianis, G.2    Anagnostopoulos, K.3
  • 61
    • 58149241362 scopus 로고    scopus 로고
    • Effect of zoledronic acid on serum angiogenic factors in patients with bone metastases
    • Tas F, Duranyildiz D, Oguz H, Camlica H, Yasasever V, Topuz E. Effect of zoledronic acid on serum angiogenic factors in patients with bone metastases. Med. Oncol. 25(3), 346-349 (2008).
    • (2008) Med. Oncol. , vol.25 , Issue.3 , pp. 346-349
    • Tas, F.1    Duranyildiz, D.2    Oguz, H.3    Camlica, H.4    Yasasever, V.5    Topuz, E.6
  • 62
    • 57549103742 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw: Who gets it and why
    • Reid IR. Osteonecrosis of the jaw: who gets it, and why? Bone 44(1), 4-10 (2009).
    • (2009) Bone , vol.44 , Issue.1 , pp. 4-10
    • Reid, I.R.1
  • 63
    • 79952761418 scopus 로고    scopus 로고
    • Randomized double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer excluding breast and prostate cancer or multiple myeloma
    • Henry DH, Costa L, Goldwasser F et al. Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma. J. Clin. Oncol. 29(9), 1125-1132 (2011).
    • (2011) J. Clin. Oncol. , vol.29 , Issue.9 , pp. 1125-1132
    • Henry, D.H.1    Costa, L.2    Goldwasser, F.3
  • 64
    • 61649123793 scopus 로고    scopus 로고
    • Osteonecrosis of the jaw under bisphosphonate and antiangiogenic therapies: Cumulative toxicity profile
    • Ayllon J, Launay-Vacher V, Medioni J et al. Osteonecrosis of the jaw under bisphosphonate and antiangiogenic therapies: cumulative toxicity profile? Ann. Oncol. 20(3), 600-601 (2009).
    • (2009) Ann. Oncol. , vol.20 , Issue.3 , pp. 600-601
    • Ayllon, J.1    Launay-Vacher, V.2    Medioni, J.3
  • 65
  • 66
    • 53449093633 scopus 로고    scopus 로고
    • Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: A genome-wide single nucleotide polymorphism analysis
    • Sarasquete ME, Garcia-Sanz R, Marin L et al. Bisphosphonate-related osteonecrosis of the jaw is associated with polymorphisms of the cytochrome P450 CYP2C8 in multiple myeloma: a genome-wide single nucleotide polymorphism analysis. Blood 112(7), 2709-2712 (2008).
    • (2008) Blood , vol.112 , Issue.7 , pp. 2709-2712
    • Sarasquete, M.E.1    Garcia-Sanz, R.2    Marin, L.3
  • 67
    • 30544449595 scopus 로고    scopus 로고
    • Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis
    • DOI 10.1242/jcs.02674
    • Michaelis UR, Fisslthaler B, Barbosa-Sicard E, Falck J, Fleming R, Busse R. Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis. J. Cell Sci. 118(Pt 23), 5489-5498 (2005). (Pubitemid 43079290)
    • (2005) Journal of Cell Science , vol.118 , Issue.23 , pp. 5489-5498
    • Michaelis, U.R.1    Fisslthaler, B.2    Barbosa-Sicard, E.3    Falck, J.R.4    Fleming, I.5    Busse, R.6
  • 68
    • 64249147273 scopus 로고    scopus 로고
    • Utility of hyperbaric oxygen in treatment of bisphosphonate-related osteonecrosis of the jaws
    • Freiberger JJ. Utility of hyperbaric oxygen in treatment of bisphosphonate-related osteonecrosis of the jaws. J. Oral Maxillofac. Surg. 67(Suppl. 5), 96-106 (2009).
    • (2009) J. Oral Maxillofac. Surg. , vol.67 , Issue.5 , pp. 96-106
    • Freiberger, J.J.1


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