-
1
-
-
80455161467
-
Methotrexate
-
th ed. Philadelphia, Mosby-Elsevier
-
th ed. Philadelphia, Mosby-Elsevier 2011; pp. 509-518.
-
(2011)
, pp. 509-518
-
-
Johnsen, A.K.1
Weinblatt, M.E.2
-
2
-
-
32444436350
-
Risk genotypes in folate dependent enzymes and their association with methotrexate related side effects in rheumatoid arthritis
-
Weisman MH, Furst DE, Park GS, et al. Risk genotypes in folate dependent enzymes and their association with methotrexate related side effects in rheumatoid arthritis. Arthritis Rheum 2006; 54: 607-612.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 607-612
-
-
Weisman, M.H.1
Furst, D.E.2
Park, G.S.3
-
3
-
-
33751401805
-
The use of low dose methotrexate in rheumatoid arthritis - are we entering a new era of therapeutic drug monitoring and pharmacogenomics?
-
Stamp L, Roberts R, Kennedy M, Barclay M, O'Donnell J, Chapman P. The use of low dose methotrexate in rheumatoid arthritis - are we entering a new era of therapeutic drug monitoring and pharmacogenomics? Biomed Pharmacother 2006; 60: 678-687.
-
(2006)
Biomed Pharmacother
, vol.60
, pp. 678-687
-
-
Stamp, L.1
Roberts, R.2
Kennedy, M.3
Barclay, M.4
O'Donnell, J.5
Chapman, P.6
-
4
-
-
10044253095
-
Pharmacogenetic approaches to rheumatoid arthritis
-
Taniguchi A, Kamatani N. Pharmacogenetic approaches to rheumatoid arthritis. Pharmacogenomics J 2004; 4: 350-353.
-
(2004)
Pharmacogenomics J
, vol.4
, pp. 350-353
-
-
Taniguchi, A.1
Kamatani, N.2
-
5
-
-
0036267170
-
Differing effects of methylene tetrahydrofolate reductase single nucleotide polymorphisms on methotrexate efficacy and toxicity in rheumatoid arthritis
-
Evans WE. Differing effects of methylene tetrahydrofolate reductase single nucleotide polymorphisms on methotrexate efficacy and toxicity in rheumatoid arthritis. Pharmacogenetics 2002; 12: 181-182.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 181-182
-
-
Evans, W.E.1
-
6
-
-
80455135381
-
Methotrexate gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis
-
Ranganathan P, Culverhouse, Marsh S. Methotrexate gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis. J Rheumatol 2008; 5: 559-569.
-
(2008)
J Rheumatol
, vol.5
, pp. 559-569
-
-
Ranganathan, P.1
Culverhouse, M.S.2
-
7
-
-
66149144789
-
Plasma total homocysteine level and methylene tetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis
-
Fujimaki C, Hayashi H, Tsuboi S, et al. Plasma total homocysteine level and methylene tetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis. Biomarkers 2009; 14: 49-54.
-
(2009)
Biomarkers
, vol.14
, pp. 49-54
-
-
Fujimaki, C.1
Hayashi, H.2
Tsuboi, S.3
-
8
-
-
0036263469
-
Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses
-
Urano W, Taniguchi A, Yamanaka H, et al. Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses. Pharmacogenetics 2002; 12: 183-190.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 183-190
-
-
Urano, W.1
Taniguchi, A.2
Yamanaka, H.3
-
9
-
-
43249121301
-
Are thymidilate synthase and methylene tetrahydrofolate reductase genes linked with methotrextae response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients
-
Ghodke Y, Chopra A, Joshi K, Patwardhan B. Are thymidilate synthase and methylene tetrahydrofolate reductase genes linked with methotrextae response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients. Clin Rheumatol 2008; 27: 787-789.
-
(2008)
Clin Rheumatol
, vol.27
, pp. 787-789
-
-
Ghodke, Y.1
Chopra, A.2
Joshi, K.3
Patwardhan, B.4
-
10
-
-
0642286407
-
Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis
-
Kumagai K, Hiyama K, Oyama T, Maeda H, Kohno N. Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis. Int J Mol Med 2003; 11: 593-600.
-
(2003)
Int J Mol Med
, vol.11
, pp. 593-600
-
-
Kumagai, K.1
Hiyama, K.2
Oyama, T.3
Maeda, H.4
Kohno, N.5
-
11
-
-
33750352061
-
Pharmacogenomic and metabolic biomarkers in the folate pathway and their association with methotrexate effects during dosage escalation in rheumatoid arthritis
-
Dervieux T, Greenstein N, Kremer J. Pharmacogenomic and metabolic biomarkers in the folate pathway and their association with methotrexate effects during dosage escalation in rheumatoid arthritis. Arthritis Rheum 2006; 54: 3095-3103.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3095-3103
-
-
Dervieux, T.1
Greenstein, N.2
Kremer, J.3
-
12
-
-
27944488639
-
Relationship between 5,10 metylene tetrahydrofolate reductase C677T gene polymorphism and methotrexate related toxicity in patients with autoimmune diseases receiving folic acid supplementation
-
Spelatos M, Papadopoulos N, Daiou C, Katodritou E, Pavlitou- Tsiontsi A, Galaropoulou V. Relationship between 5,10 metylene tetrahydrofolate reductase C677T gene polymorphism and methotrexate related toxicity in patients with autoimmune diseases receiving folic acid supplementation. Ann Rheum Dis 2005; 64: 1791-1792.
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 1791-1792
-
-
Spelatos, M.1
Papadopoulos, N.2
Daiou, C.3
Katodritou, E.4
Pavlitou-Tsiontsi, A.5
Galaropoulou, V.6
-
13
-
-
33846482501
-
Correlation between methotrexate efficacy and toxicity with C677T polymorphism of the methylene tatrahydrofolate gene in rheumatoid arthritis patients on folate supplementation
-
Aggarwal P, Naik S, Mishra KP, Aggarwal A, Misra R. Correlation between methotrexate efficacy and toxicity with C677T polymorphism of the methylene tatrahydrofolate gene in rheumatoid arthritis patients on folate supplementation. Indian Med J 2006; 124: 521-526.
-
(2006)
Indian Med J
, vol.124
, pp. 521-526
-
-
Aggarwal, P.1
Naik, S.2
Mishra, K.P.3
Aggarwal, A.4
Misra, R.5
-
14
-
-
33646354882
-
Efficacy and toxicity of methotrexate in early rheumatoid arhritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes
-
Wessels J, Bouwstra J, Heijmans BT, et al. Efficacy and toxicity of methotrexate in early rheumatoid arhritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes. Arthritis Rheum 2006; 54: 1087-1095.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1087-1095
-
-
Wessels, J.1
Bouwstra, J.2
Heijmans, B.T.3
-
15
-
-
55349093579
-
Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: A study of polymorphisms affecting methotrexate transport and folate metabolism
-
Grabar BP, Logar D, Lestan B, Dolzan V. Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism. Eur J Clin Pharmacol 2008; 64: 1057-1068.
-
(2008)
Eur J Clin Pharmacol
, vol.64
, pp. 1057-1068
-
-
Grabar, B.P.1
Logar, D.2
Lestan, B.3
Dolzan, V.4
-
16
-
-
4644349995
-
Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene
-
Berkun Y, Levatovsky D, Rubinow A et al. Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene. Ann Rheum Dis 2004; 63: 1227-1231.
-
(2004)
Ann Rheum Dis
, vol.63
, pp. 1227-1231
-
-
Berkun, Y.1
Levatovsky, D.2
Rubinow, A.3
-
17
-
-
67651146762
-
Metylene tetrahydrofolate reductase polymorphisms and methotrexate: No associaiton with response to therapy nor with drug-related adverse events in an Italian population of rheumatic patients
-
Taraborelli M, Andreoli L, Archetti S, Ferrari M, Cattaneo R, Tincani A. Metylene tetrahydrofolate reductase polymorphisms and methotrexate: no associaiton with response to therapy nor with drug-related adverse events in an Italian population of rheumatic patients. Clin Exp Rheumatol 2009; 27(3): 499-502.
-
(2009)
Clin Exp Rheumatol
, vol.27
, Issue.3
, pp. 499-502
-
-
Taraborelli, M.1
Andreoli, L.2
Archetti, S.3
Ferrari, M.4
Cattaneo, R.5
Tincani, A.6
-
18
-
-
33747805632
-
Racial or ethnic differences in allele frequencies of single nucleotide polymorphisms in the methylene tetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis
-
Hughes LB, Beasley TM, Patel H, et al. Racial or ethnic differences in allele frequencies of single nucleotide polymorphisms in the methylene tetrahydrofolate reductase gene and their influence on response to methotrexate in rheumatoid arthritis. Ann Rheum Dis 2006; 65: 1213-1218.
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 1213-1218
-
-
Hughes, L.B.1
Beasley, T.M.2
Patel, H.3
-
19
-
-
0035157121
-
The C677T mutation in the methylenetetrahydrofolate reductase gene: A genetic risk factor for methotrexate- related elevation of liver enzymes in rheumatoid arthritis patients
-
Van Ede AE, Laan RF, Blom HJ, et al. The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate- related elevation of liver enzymes in rheumatoid arthritis patients. Arthritis Rheum 2001; 44: 2525-2530.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 2525-2530
-
-
van Ede, A.E.1
Laan, R.F.2
Blom, H.J.3
-
20
-
-
75149115724
-
Associations between the C677T and A1298C polymorphisms of MTHFR and the efficacy and toxicity of methotrexate in rheumatoid arthritis: A meta-analysis
-
Lee YH, Song GG. Associations between the C677T and A1298C polymorphisms of MTHFR and the efficacy and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis. Clin Drug Investig 2010; 30(2): 101-108.
-
(2010)
Clin Drug Investig
, vol.30
, Issue.2
, pp. 101-108
-
-
Lee, Y.H.1
Song, G.G.2
-
21
-
-
0033007397
-
Influence of sulphasalazine, methotrexate, and the combination of both on plasma homocysteine concentrations in patients with rheumatoid arthritis
-
Haagsma CJ, Blom HJ, van Riel PL, et al. Influence of sulphasalazine, methotrexate, and the combination of both on plasma homocysteine concentrations in patients with rheumatoid arthritis. Ann Rheum Dis 1999; 58: 79-84.
-
(1999)
Ann Rheum Dis
, vol.58
, pp. 79-84
-
-
Haagsma, C.J.1
Blom, H.J.2
van Riel, P.L.3
-
22
-
-
37349048292
-
677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis
-
Kurzawski M, Pawlik A, Safranow K, Herzynska M, Drozdzik M. 677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis. Pharmacogenomics 2007; 8(11): 1551-1559.
-
(2007)
Pharmacogenomics
, vol.8
, Issue.11
, pp. 1551-1559
-
-
Kurzawski, M.1
Pawlik, A.2
Safranow, K.3
Herzynska, M.4
Drozdzik, M.5
-
23
-
-
77952425589
-
Polymorphisms within the folate Pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate
-
Stamp LK, Chapman PT, O'Donnell JL, et al. Polymorphisms within the folate Pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate. Pharmacogenet Genomics 2010; 20(6): 367-376.
-
(2010)
Pharmacogenet Genomics
, vol.20
, Issue.6
, pp. 367-376
-
-
Stamp, L.K.1
Chapman, P.T.2
O'Donnell, J.L.3
-
24
-
-
79960646716
-
Polymorphisms C677T and A1298C in the MTHFR gene in Mexican patients with rheumatoid arthritis treated with methotrexate: Implication with elevation of transaminases
-
Mena JP, Salazar-Paramo M, Gonzalez-Lopez L, et al. Polymorphisms C677T and A1298C in the MTHFR gene in Mexican patients with rheumatoid arthritis treated with methotrexate: implication with elevation of transaminases. Pharmacogenomics J 2011; 11: 287-291.
-
(2011)
Pharmacogenomics J
, vol.11
, pp. 287-291
-
-
Mena, J.P.1
Salazar-Paramo, M.2
Gonzalez-Lopez, L.3
-
25
-
-
0023945481
-
The American Rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis
-
Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988; 31: 315-324.
-
(1988)
Arthritis Rheum
, vol.31
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
-
26
-
-
0025124368
-
A toxicity index for comparison of side effects among different drugs
-
Fries JF, Spitz PW, Williams CA, Bloch DA, Singh G, Hubert HB. A toxicity index for comparison of side effects among different drugs. Arthritis Rheum 1990; 33: 121-130.
-
(1990)
Arthritis Rheum
, vol.33
, pp. 121-130
-
-
Fries, J.F.1
Spitz, P.W.2
Williams, C.A.3
Bloch, D.A.4
Singh, G.5
Hubert, H.B.6
-
27
-
-
0025086688
-
Judging disease activity in clinical practice in rheumatoid arthritis: First step in the development of a disease activity score
-
Van der Heijde DM, van 't Hof MA, van Riel PL, et al. Judging disease activity in clinical practice in rheumatoid arthritis: first step in the development of a disease activity score. Ann Rheum Dis 1990; 49: 916-920.
-
(1990)
Ann Rheum Dis
, vol.49
, pp. 916-920
-
-
van der Heijde, D.M.1
van 't Hof, M.A.2
van Riel, P.L.3
-
28
-
-
33644794107
-
The Health Assessment Questionnaire (HAQ)
-
Bruce B, Fries JF. The Health Assessment Questionnaire (HAQ). Clin Exp Rheumatol 2005; 23(5 Suppl 39): 14-18.
-
(2005)
Clin Exp Rheumatol
, vol.23
, Issue.5 SUPPL. 39
, pp. 14-18
-
-
Bruce, B.1
Fries, J.F.2
-
29
-
-
0024284028
-
A simple salting out procedure for extracting DNA from human nucleated cells
-
Miller SA, Dykes DD, Polesky HF. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 1988; 16: 1215-1217.
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 1215-1217
-
-
Miller, S.A.1
Dykes, D.D.2
Polesky, H.F.3
-
30
-
-
1542359519
-
Folate supplementation and methotrexate treatment in rheumatoid arthritis: A review
-
Whittle SL, Hughes RA. Folate supplementation and methotrexate treatment in rheumatoid arthritis: A review. Rheumatology 2004; 43: 267-271.
-
(2004)
Rheumatology
, vol.43
, pp. 267-271
-
-
Whittle, S.L.1
Hughes, R.A.2
-
31
-
-
78650567202
-
Folate supplementation during methotrexate therapy for rheumatoid arthritis
-
Morgan SL, Baggott JE. Folate supplementation during methotrexate therapy for rheumatoid arthritis. Clin Exp Rheumatol 2010; 28(5 Suppl 61): 102-109.
-
(2010)
Clin Exp Rheumatol
, vol.28
, Issue.5 SUPPL. 61
, pp. 102-109
-
-
Morgan, S.L.1
Baggott, J.E.2
|