-
1
-
-
0025084541
-
The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis: Results of twometaanalyses
-
Oct
-
Felson DT, Anderson JJ, Meenan RF. The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis: results of twometaanalyses. Arthritis Rheum 1990 Oct; 33 (10): 1449-1461
-
(1990)
Arthritis Rheum
, vol.33
, Issue.10
, pp. 1449-1461
-
-
Felson, D.T.1
Anderson, J.J.2
Meenan, R.F.3
-
2
-
-
2342499810
-
Toward a better understanding of methotrexate
-
May
-
Kremer JM. Toward a better understanding of methotrexate. Arthritis Rheum 2004 May; 50 (5): 1370-1382
-
(2004)
Arthritis Rheum
, vol.50
, Issue.5
, pp. 1370-1382
-
-
Kremer, J.M.1
-
3
-
-
0036902026
-
The rheumatoid arthritis patient in the clinic: Comparing more than 1300 consecutive DMARD courses
-
Dec
-
Aletaha D, Smolen JS. The rheumatoid arthritis patient in the clinic: comparing more than 1300 consecutive DMARD courses. Rheumatology (Oxford) 2002 Dec; 41 (12): 1367-1374
-
(2002)
Rheumatology (Oxford)
, vol.41
, Issue.12
, pp. 1367-1374
-
-
Aletaha, D.1
Smolen, J.S.2
-
4
-
-
0025994854
-
Methotrexate: Mechanism of action, pharmacokinetics, clinical indications, and toxicity
-
Jun
-
Grosflam J, Weinblatt ME. Methotrexate: mechanism of action, pharmacokinetics, clinical indications, and toxicity. Curr Opin Rheumatol 1991 Jun; 3 (3): 363-368
-
(1991)
Curr Opin Rheumatol
, vol.3
, Issue.3
, pp. 363-368
-
-
Grosflam, J.1
Weinblatt, M.E.2
-
5
-
-
0031904465
-
Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)
-
Aug
-
Goyette P, Pai A, Milos R, et al. Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR). Mamm Genome 1998 Aug; 9 (8): 652-656
-
(1998)
Mamm Genome
, vol.9
, Issue.8
, pp. 652-656
-
-
Goyette, P.1
Pai, A.2
Milos, R.3
-
6
-
-
0036178211
-
The frequent 5,10- methylenetetrahydrofolate reductase C677T polymorphism is associated with a common haplotype in whites, Japanese, and Africans
-
Mar
-
Rosenberg N, Murata M, Ikeda Y, et al. The frequent 5,10- methylenetetrahydrofolate reductase C677T polymorphism is associated with a common haplotype in whites, Japanese, and Africans. Am J Hum Genet 2002 Mar; 70 (3): 758-762
-
(2002)
Am J Hum Genet
, vol.70
, Issue.3
, pp. 758-762
-
-
Rosenberg, N.1
Murata, M.2
Ikeda, Y.3
-
7
-
-
0031971515
-
A second common mutation in the methylenetetrahydrofolate reductase gene: An additional risk factor for neural-tube defects?
-
DOI 10.1086/301825
-
van der Put NM, Gabreels F, Stevens EM, et al. A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects? Am J Hum Genet 1998 May; 62 (5): 1044-1051 (Pubitemid 28199004)
-
(1998)
American Journal of Human Genetics
, vol.62
, Issue.5
, pp. 1044-1051
-
-
Van Der Put, N.M.J.1
Gabreels, F.2
Stevens, E.M.B.3
Smeitink, J.A.M.4
Trijbels, F.J.M.5
Eskes, T.K.A.B.6
Van Den Heuvel, L.P.7
Blom, H.J.8
-
8
-
-
34248594127
-
Validation of the associations between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: A proposal for prospective pharmacogenomic study in clinical practice
-
Jun
-
Taniguchi A, Urano W, Tanaka E, et al. Validation of the associations between single nucleotide polymorphisms or haplotypes and responses to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis: a proposal for prospective pharmacogenomic study in clinical practice. Pharmacogenet Genomics 2007 Jun; 17 (6): 383-390
-
(2007)
Pharmacogenet Genomics
, vol.17
, Issue.6
, pp. 383-390
-
-
Taniguchi, A.1
Urano, W.2
Tanaka, E.3
-
9
-
-
33846482501
-
Correlation between methotrexate efficacy and toxicity with C677T polymorphism of the methylenetetrahydrofolate gene in rheumatoid arthritis patients on folate supplementation
-
Nov
-
Aggarwal P, Naik S, Mishra KP, et al. Correlation between methotrexate efficacy and toxicity with C677T polymorphism of the methylenetetrahydrofolate gene in rheumatoid arthritis patients on folate supplementation. Indian J Med Res 2006 Nov; 124 (5): 521-526
-
(2006)
Indian J Med Res
, vol.124
, Issue.5
, pp. 521-526
-
-
Aggarwal, P.1
Naik, S.2
Mishra, K.P.3
-
10
-
-
33745781130
-
Cost-effectiveness analysis of MTHFR polymorphism screening by polymerase chain reaction in Korean patients with rheumatoid arthritis receiving methotrexate
-
Jul
-
Kim SK, Jun JB, El-Sohemy A, et al. Cost-effectiveness analysis of MTHFR polymorphism screening by polymerase chain reaction in Korean patients with rheumatoid arthritis receiving methotrexate. J Rheumatol 2006 Jul; 33 (7): 1266-1274
-
(2006)
J Rheumatol
, vol.33
, Issue.7
, pp. 1266-1274
-
-
Kim, S.K.1
Jun, J.B.2
El-Sohemy, A.3
-
11
-
-
33646354882
-
Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes
-
Apr
-
Wessels JA, de Vries-Bouwstra JK, Heijmans BT, et al. Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes. Arthritis Rheum 2006 Apr; 54 (4): 1087-1095
-
(2006)
Arthritis Rheum
, vol.54
, Issue.4
, pp. 1087-1095
-
-
Wessels, J.A.1
De Vries-Bouwstra, J.K.2
Heijmans, B.T.3
-
12
-
-
4644349995
-
Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene
-
Oct
-
Berkun Y, Levartovsky D, Rubinow A, et al. Methotrexate related adverse effects in patients with rheumatoid arthritis are associated with the A1298C polymorphism of the MTHFR gene. Ann Rheum Dis 2004 Oct; 63 (10): 1227-1231
-
(2004)
Ann Rheum Dis
, vol.63
, Issue.10
, pp. 1227-1231
-
-
Berkun, Y.1
Levartovsky, D.2
Rubinow, A.3
-
13
-
-
0642286407
-
Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis
-
May
-
Kumagai K, Hiyama K, Oyama T, et al. Polymorphisms in the thymidylate synthase and methylenetetrahydrofolate reductase genes and sensitivity to the low-dose methotrexate therapy in patients with rheumatoid arthritis. Int J Mol Med 2003 May; 11 (5): 593-600
-
(2003)
Int J Mol Med
, vol.11
, Issue.5
, pp. 593-600
-
-
Kumagai, K.1
Hiyama, K.2
Oyama, T.3
-
14
-
-
0035157121
-
The C677T mutation in the methylenetetrahydrofolate reductase gene: A genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients
-
Nov
-
van Ede AE, Laan RF, Blom HJ, et al. The C677T mutation in the methylenetetrahydrofolate reductase gene: a genetic risk factor for methotrexate-related elevation of liver enzymes in rheumatoid arthritis patients. Arthritis Rheum 2001 Nov; 44 (11): 2525-2530
-
(2001)
Arthritis Rheum
, vol.44
, Issue.11
, pp. 2525-2530
-
-
Van Ede, A.E.1
Laan, R.F.2
Blom, H.J.3
-
15
-
-
37349048292
-
677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis
-
DOI 10.2217/14622416.8.11.1551
-
Kurzawski M, Pawlik A, Safranow K, et al. 677C>T and 1298A>C MTHFR polymorphisms affect methotrexate treatment outcome in rheumatoid arthritis. Pharmacogenomics 2007 Nov; 8 (11): 1551-1559 (Pubitemid 350286399)
-
(2007)
Pharmacogenomics
, vol.8
, Issue.11
, pp. 1551-1559
-
-
Kurzawski, M.1
Pawlik, A.2
Safranow, K.3
Herczynska, M.4
Drozdzik, M.5
-
16
-
-
0030720013
-
Meta-analysis: Principles and procedures
-
Dec 6
-
Egger M, Smith GD, Phillips AN. Meta-analysis: principles and procedures. BMJ 1997 Dec 6; 315 (7121): 1533-1537
-
(1997)
BMJ
, vol.315
, Issue.7121
, pp. 1533-1537
-
-
Egger, M.1
Smith, G.D.2
Phillips, A.N.3
-
17
-
-
0030922816
-
Bias in metaanalysis detected by a simple, graphical test
-
Sep 13
-
Egger M, Davey Smith G, Schneider M, et al. Bias in metaanalysis detected by a simple, graphical test. BMJ 1997 Sep 13; 315 (7109): 629-634
-
(1997)
BMJ
, vol.315
, Issue.7109
, pp. 629-634
-
-
Egger, M.1
Davey Smith, G.2
Schneider, M.3
-
18
-
-
0037098199
-
Quantifying heterogeneity in a meta-analysis
-
Jun 15
-
Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002 Jun 15; 21 (11): 1539-1558
-
(2002)
Stat Med
, vol.21
, Issue.11
, pp. 1539-1558
-
-
Higgins, J.P.1
Thompson, S.G.2
-
19
-
-
0036263469
-
Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses
-
Apr
-
UranoW, Taniguchi A, Yamanaka H, et al. Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses. Pharmacogenetics 2002 Apr; 12 (3): 183-190
-
(2002)
Pharmacogenetics
, vol.12
, Issue.3
, pp. 183-190
-
-
Urano, W.1
Taniguchi, A.2
Yamanaka, H.3
-
20
-
-
41849115973
-
Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis
-
Apr
-
Ranganathan P, Culverhouse R, Marsh S, et al. Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis. J Rheumatol 2008 Apr; 35 (4): 572-579
-
(2008)
J Rheumatol
, vol.35
, Issue.4
, pp. 572-579
-
-
Ranganathan, P.1
Culverhouse, R.2
Marsh, S.3
-
21
-
-
32444436350
-
Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis
-
Feb
-
Weisman MH, Furst DE, Park GS, et al. Risk genotypes in folate-dependent enzymes and their association with methotrexate-related side effects in rheumatoid arthritis. Arthritis Rheum 2006 Feb; 54 (2): 607-612
-
(2006)
Arthritis Rheum
, vol.54
, Issue.2
, pp. 607-612
-
-
Weisman, M.H.1
Furst, D.E.2
Park, G.S.3
-
22
-
-
43249121301
-
Are thymidylate synthase and methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy toxicity) in Indian (Asian) rheumatoid arthritis patients?
-
Jun
-
Ghodke Y, Chopra A, Joshi K, et al. Are thymidylate synthase and methylene tetrahydrofolate reductase genes linked with methotrexate response (efficacy, toxicity) in Indian (Asian) rheumatoid arthritis patients? Clin Rheumatol 2008 Jun; 27 (6): 787-789
-
(2008)
Clin Rheumatol
, vol.27
, Issue.6
, pp. 787-789
-
-
Ghodke, Y.1
Chopra, A.2
Joshi, K.3
-
23
-
-
0030068817
-
Development and validation of the European League Against Rheumatism response criteria for rheumatoid arthritis: Comparison with the preliminary American College of Rheumatology and the World Health Organization/ International League Against Rheumatism Criteria
-
Jan
-
van Gestel AM, Prevoo ML, van 't Hof MA, et al. Development and validation of the European League Against Rheumatism response criteria for rheumatoid arthritis: comparison with the preliminary American College of Rheumatology and the World Health Organization/ International League Against Rheumatism Criteria. Arthritis Rheum 1996 Jan; 39 (1): 34-40
-
(1996)
Arthritis Rheum
, vol.39
, Issue.1
, pp. 34-40
-
-
Van Gestel, A.M.1
Prevoo, M.L.2
Van'T Hof, M.A.3
-
24
-
-
0035313224
-
Biological and clinical implications of the MTHFR C677T polymorphism
-
Ueland PM, Hustad S, Schneede J, et al. Biological and clinical implications of the MTHFR C677T polymorphism. Trends Pharmacol Sci 2001; 22:195-201
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 195-201
-
-
Ueland, P.M.1
Hustad, S.2
Schneede, J.3
-
25
-
-
0031687887
-
A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity
-
Weisberg I, Tran P, Christensen B, et al. A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Genet Metab 1998; 64:169-172
-
(1998)
Mol Genet Metab
, vol.64
, pp. 169-172
-
-
Weisberg, I.1
Tran, P.2
Christensen, B.3
-
26
-
-
0034944211
-
Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: A forty-eight week, multicenter, randomized, double-blind, placebo-controlled study
-
Jul
-
van Ede AE, Laan RF, Rood MJ, et al. Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study. Arthritis Rheum 2001 Jul; 44 (7): 1515-1524
-
(2001)
Arthritis Rheum
, vol.44
, Issue.7
, pp. 1515-1524
-
-
Van Ede, A.E.1
Laan, R.F.2
Rood, M.J.3
-
27
-
-
0031904465
-
Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR)
-
Goyelte P, Pai A, Milos R, et al. Gene structure of human and mouse methylenetetrahydrofolate reductase (MTHFR). Mamm Genome 1998; 9: 652-656
-
(1998)
Mamm Genome
, vol.9
, pp. 652-656
-
-
Goyelte, P.1
Pai, A.2
Milos, R.3
-
28
-
-
65649111229
-
Metaanalysis of methylenetetrahydrofolate reductase (MTHFR) polymorphisms affecting methotrexate toxicity
-
Mar
-
Fisher MC, Cronstein BN. Metaanalysis of methylenetetrahydrofolate reductase (MTHFR) polymorphisms affecting methotrexate toxicity. J Rheumatol 2009 Mar; 36 (3): 539-545
-
(2009)
J Rheumatol
, vol.36
, Issue.3
, pp. 539-545
-
-
Fisher, M.C.1
Cronstein, B.N.2
|