Methylenetetrahydrofolate reductase polymorphisms and methotrexate: No association with response to therapy nor with drug-related adverse events in an Italian population of rheumatic patients

Clinical and Experimental Rheumatology

Volumn 27, Issue 3, 2009, Pages 499-502

  Taraborelli, Mara ^a   Andreoli, Laura ^a   Archetti, Silvana ^b   Ferrari, Maria ^b   Cattaneo, Roberto ^a   Tincani, Angela ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b Spedali Civili   (Italy)

Author keywords

Efficacy; Folic acid; Genetic polymorphisms; Methotrexate; Methylenetetrahydrofolate reductase; Rheumatic diseases; Rheumatoid arthritis; Toxicity

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALANINE AMINOTRANSFERASE; FOLIC ACID; METHOTREXATE;

ABDOMINAL PAIN; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALOPECIA; ANKYLOSING SPONDYLITIS; ANOREXIA; ARTICLE; CONTROLLED STUDY; COUGHING; DIARRHEA; DISEASE CONTROL; DIZZINESS; DYSPNEA; FATIGUE; FEMALE; FEVER; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC SCREENING; GENOTYPE; HEADACHE; HUMAN; HUMAN CELL; INTERSTITIAL PNEUMONIA; ITALY; LEUKOPENIA; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALAISE; MALE; MEGALOBLASTIC ANEMIA; MOOD DISORDER; NAUSEA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSORIATIC ARTHRITIS; RHEUMATOID ARTHRITIS; SIDE EFFECT; SKIN ULCER; THROMBOCYTOPENIA; TREATMENT RESPONSE; VITAMIN SUPPLEMENTATION; VOMITING; WEIGHT REDUCTION;

ADULT; ANTIRHEUMATIC AGENTS; ARTHRITIS, PSORIATIC; ARTHRITIS, RHEUMATOID; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; ITALY; MALE; METHOTREXATE; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RETROSPECTIVE STUDIES; SPONDYLITIS, ANKYLOSING; TREATMENT OUTCOME;

EID: 67651146762     PISSN: 0392856X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

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