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Volumn 6, Issue 11, 2011, Pages

Oscillatory protein expression dynamics endows stem cells with robust differentiation potential

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL DIFFERENTIATION; CELL HETEROGENEITY; CELL INTERACTION; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; GENE REGULATORY NETWORK; GENETIC SCREENING; OSCILLATION; PROTEIN EXPRESSION; SIMULATION; STEM CELL; BIOLOGICAL MODEL; CYTOLOGY; METABOLISM;

EID: 80455131192     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027232     Document Type: Article
Times cited : (115)

References (55)
  • 3
    • 0034712109 scopus 로고    scopus 로고
    • Out of Eden: stem cells and their niches
    • Watt FM, Brigid L, Hogan M, (2000) Out of Eden: stem cells and their niches. Science 287: 1427-1430.
    • (2000) Science , vol.287 , pp. 1427-1430
    • Watt, F.M.1    Brigid, L.2    Hogan, M.3
  • 4
    • 0025641727 scopus 로고
    • Stem cells: attributes, cycles, apirals, pitfalls and uncertainties
    • Potten CS, Loeffer M, (1990) Stem cells: attributes, cycles, apirals, pitfalls and uncertainties. Development 110: 1001-1020.
    • (1990) Development , vol.110 , pp. 1001-1020
    • Potten, C.S.1    Loeffer, M.2
  • 5
    • 0030933062 scopus 로고    scopus 로고
    • Regulatory mechanisms in stem cell biology
    • Morrison SJ, Shah NM, Anderson DJ, (1997) Regulatory mechanisms in stem cell biology. Cell 88: 287-298.
    • (1997) Cell , vol.88 , pp. 287-298
    • Morrison, S.J.1    Shah, N.M.2    Anderson, D.J.3
  • 6
    • 84925132349 scopus 로고    scopus 로고
    • Biological Physics of The Developing Embryo
    • Cambridge Univ. Press, Cambridge, UK
    • Forgacs G, Newman SA, (2006) Biological Physics of The Developing Embryo. Cambridge Univ. Press, Cambridge, UK.
    • (2006)
    • Forgacs, G.1    Newman, S.A.2
  • 7
    • 66449090934 scopus 로고    scopus 로고
    • Reprogramming cell fates: reconciling rarity with robustness
    • Huang S, (2009) Reprogramming cell fates: reconciling rarity with robustness. Bioessays 31: 546-560.
    • (2009) Bioessays , vol.31 , pp. 546-560
    • Huang, S.1
  • 8
    • 0004078878 scopus 로고
    • The Strategy of the Genes
    • London, George Allen & Unwin, London, UK
    • Waddington C, (1957) The Strategy of the Genes. London George Allen & Unwin, London, UK.
    • (1957)
    • Waddington, C.1
  • 9
    • 22144491187 scopus 로고    scopus 로고
    • Differential equations, dynamical systems, and an introduction to chaos
    • Academic Press, San Diego, USA
    • Hirsch MW, Smale S, Devaney RL, (2003) Differential equations, dynamical systems, and an introduction to chaos. Academic Press, San Diego, USA.
    • (2003)
    • Hirsch, M.W.1    Smale, S.2    Devaney, R.L.3
  • 10
    • 0003932731 scopus 로고
    • Temporal Organizations in Cells
    • Academic Press, San Diego, USA
    • Goodwin BC, (1963) Temporal Organizations in Cells. Academic Press, San Diego, USA.
    • (1963)
    • Goodwin, B.C.1
  • 11
    • 0014489272 scopus 로고
    • Metabolic stability and epigenesis in randomly connected nets
    • Kauffman SA, (1969) Metabolic stability and epigenesis in randomly connected nets. J Theor Biol 22: 437-467.
    • (1969) J Theor Biol , vol.22 , pp. 437-467
    • Kauffman, S.A.1
  • 12
    • 0003694798 scopus 로고
    • The Origins of Order: Self-Organization and Selection in Evolution
    • Oxford University Press, Oxford, UK
    • Kauffman SA, (1993) The Origins of Order: Self-Organization and Selection in Evolution. Oxford University Press, Oxford, UK.
    • (1993)
    • Kauffman, S.A.1
  • 13
    • 18144408736 scopus 로고    scopus 로고
    • Cell fates as high-dimensional attractor states of a complex gene regulatory network
    • Huang S, Eichler G, Bar-Yam Y, Ingber DE, (2007) Cell fates as high-dimensional attractor states of a complex gene regulatory network. Phys Rev Lett 94 (12): 128701.
    • (2007) Phys Rev Lett , vol.94 , Issue.12 , pp. 128701
    • Huang, S.1    Eichler, G.2    Bar-Yam, Y.3    Ingber, D.E.4
  • 14
    • 44349162752 scopus 로고    scopus 로고
    • Transcriptome-wide noise controls lineage choice in mammalian progenitor cells
    • Chang HH, Hemberg M, Barahona M, Ingber DE, Huang S, (2008) Transcriptome-wide noise controls lineage choice in mammalian progenitor cells. Nature 453: 544-548.
    • (2008) Nature , vol.453 , pp. 544-548
    • Chang, H.H.1    Hemberg, M.2    Barahona, M.3    Ingber, D.E.4    Huang, S.5
  • 15
    • 0031031823 scopus 로고    scopus 로고
    • Isologous diversification: a theory of cell differentiation
    • Kaneko K, Yomo T, (1997) Isologous diversification: a theory of cell differentiation. Bull Math Biol 59: 139-196.
    • (1997) Bull Math Biol , vol.59 , pp. 139-196
    • Kaneko, K.1    Yomo, T.2
  • 16
    • 0032127725 scopus 로고    scopus 로고
    • Emergence of rules in cell society: differentiation, hierarchy, and stability
    • Furusawa C, Kaneko K, (1998) Emergence of rules in cell society: differentiation, hierarchy, and stability. Bull Math Biol 60: 659-687.
    • (1998) Bull Math Biol , vol.60 , pp. 659-687
    • Furusawa, C.1    Kaneko, K.2
  • 17
    • 0035925930 scopus 로고    scopus 로고
    • Theory of robustness of irreversible differentiation in a stem cell system: chaos hypothesis.
    • Furusawa C, Kaneko K, (2001) Theory of robustness of irreversible differentiation in a stem cell system: chaos hypothesis.J Theor Biol. 209 (4): 395-416.
    • (2001) J Theor Biol , vol.209 , Issue.4 , pp. 395-416
    • Furusawa, C.1    Kaneko, K.2
  • 18
    • 67449141030 scopus 로고    scopus 로고
    • Chaotic expression dynamics implies pluripotency: when theory and experimentation meet
    • Furusawa C, Kaneko K, (2009) Chaotic expression dynamics implies pluripotency: when theory and experimentation meet. Biol Direct 4: 17.
    • (2009) Biol Direct , vol.4 , pp. 17
    • Furusawa, C.1    Kaneko, K.2
  • 19
    • 0002011401 scopus 로고
    • The chemical basis of morphogenesis
    • Turing, AM, (1952) The chemical basis of morphogenesis. Phil Trans Roy Soc B 237 (641): 37-72.
    • (1952) Phil Trans Roy Soc B , vol.237 , Issue.641 , pp. 37-72
    • Turing, A.M.1
  • 20
    • 0004821368 scopus 로고
    • Proportion regulation of biological cells in globally coupled nonlinear systems
    • Mizuguchi T, Sano M, (1995) Proportion regulation of biological cells in globally coupled nonlinear systems. Phys Rev Lett 75: 966-969.
    • (1995) Phys Rev Lett , vol.75 , pp. 966-969
    • Mizuguchi, T.1    Sano, M.2
  • 21
    • 45149135778 scopus 로고
    • Clustering, coding, switching, hierarchical ordering, and control in network of chaotic elements
    • Kaneko K, (1990) Clustering, coding, switching, hierarchical ordering, and control in network of chaotic elements. Physica D 41: 137-172.
    • (1990) Physica D , vol.41 , pp. 137-172
    • Kaneko, K.1
  • 22
    • 0002351213 scopus 로고
    • Cell division, differentiation, and dynamic clustering
    • Kaneko K, Yomo T, (1994) Cell division, differentiation, and dynamic clustering. Physica D 75: 89-102.
    • (1994) Physica D , vol.75 , pp. 89-102
    • Kaneko, K.1    Yomo, T.2
  • 23
    • 34948872504 scopus 로고    scopus 로고
    • Multistability and Clustering in a Population of Synthetic Genetic Oscillators via Phase-Repulsive Cell-to-Cell Communication
    • Ullner E, Zaikin A, Volkov EI, García-Ojalvo J, (2007) Multistability and Clustering in a Population of Synthetic Genetic Oscillators via Phase-Repulsive Cell-to-Cell Communication, Phys Rev Lett. 99: 148103.
    • (2007) Phys Rev Lett , vol.99 , pp. 148103
    • Ullner, E.1    Zaikin, A.2    Volkov, E.I.3    García-Ojalvo, J.4
  • 24
    • 47849106044 scopus 로고    scopus 로고
    • Regulative differentiation as bifurcation of interacting cell population
    • Nakajima A, Kaneko K, (2008) Regulative differentiation as bifurcation of interacting cell population. J Theor Biol 253: 779-787.
    • (2008) J Theor Biol , vol.253 , pp. 779-787
    • Nakajima, A.1    Kaneko, K.2
  • 25
    • 0037174670 scopus 로고    scopus 로고
    • Network motifs: simple building blocks of complex networks
    • Milo R, Shen-Orr S, Itzkovitz S, Kashtan N, Chklovskii D, et al. (2002) Network motifs: simple building blocks of complex networks. Science 298 (5594): 824-827.
    • (2002) Science , vol.298 , Issue.5594 , pp. 824-827
    • Milo, R.1    Shen-Orr, S.2    Itzkovitz, S.3    Kashtan, N.4    Chklovskii, D.5
  • 26
    • 0034688173 scopus 로고    scopus 로고
    • A synthetic oscillatory network of transcriptional regulators
    • Elowitz MB, Leibler S, (2000) A synthetic oscillatory network of transcriptional regulators. Nature 403 (6767): 335-338.
    • (2000) Nature , vol.403 , Issue.6767 , pp. 335-338
    • Elowitz, M.B.1    Leibler, S.2
  • 27
    • 46849090495 scopus 로고    scopus 로고
    • Robust, Tunable Biological Oscillations from Interlinked Positive and Negative Feedback Loops
    • Tsai TY, Choi YS, Ma W, Pomering JR, Tang C, et al. (2008) Robust, Tunable Biological Oscillations from Interlinked Positive and Negative Feedback Loops, Science 321: 126-129.
    • (2008) Science , vol.321 , pp. 126-129
    • Tsai, T.Y.1    Choi, Y.S.2    Ma, W.3    Pomering, J.R.4    Tang, C.5
  • 28
    • 70450228872 scopus 로고    scopus 로고
    • The combination of positive and negative feedback loops confers exquisite flexibility to biochemical switches
    • Pfuety B, Kaneko K, (2009) The combination of positive and negative feedback loops confers exquisite flexibility to biochemical switches, Physical Biology 6: 046013.
    • (2009) Physical Biology , vol.6 , pp. 046013
    • Pfuety, B.1    Kaneko, K.2
  • 30
    • 34547604468 scopus 로고    scopus 로고
    • Noise in gene expression determines cell fate in Bacillus subtilis
    • Maamar H, Raj A, Dubnau D, (2007) Noise in gene expression determines cell fate in Bacillus subtilis. Science 317 (5837): 526-529.
    • (2007) Science , vol.317 , Issue.5837 , pp. 526-529
    • Maamar, H.1    Raj, A.2    Dubnau, D.3
  • 31
    • 42149192008 scopus 로고    scopus 로고
    • Identification and characterization of subpopulations in undifferentiated ES cell culture
    • Toyooka Y, Shimosato D, Murakami K, Takahashi K, Niwa H, (2008) Identification and characterization of subpopulations in undifferentiated ES cell culture. Development 135 (5): 909-918.
    • (2008) Development , vol.135 , Issue.5 , pp. 909-918
    • Toyooka, Y.1    Shimosato, D.2    Murakami, K.3    Takahashi, K.4    Niwa, H.5
  • 32
    • 37549002155 scopus 로고    scopus 로고
    • Nanog safeguards pluripotency and mediates germline development
    • Chambers I, Silva J, Colby D, Nichols J, Nijmeijer B, et al. (2007) Nanog safeguards pluripotency and mediates germline development. Nature 450 (7173): 1230-1234.
    • (2007) Nature , vol.450 , Issue.7173 , pp. 1230-1234
    • Chambers, I.1    Silva, J.2    Colby, D.3    Nichols, J.4    Nijmeijer, B.5
  • 33
    • 53049092465 scopus 로고    scopus 로고
    • Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states
    • Hayashi K, Lopes SM, Tang F, Surani MA, (2008) Dynamic equilibrium and heterogeneity of mouse pluripotent stem cells with distinct functional and epigenetic states. Cell Stem Cell 3: 391-401.
    • (2008) Cell Stem Cell , vol.3 , pp. 391-401
    • Hayashi, K.1    Lopes, S.M.2    Tang, F.3    Surani, M.A.4
  • 34
    • 69249215528 scopus 로고    scopus 로고
    • The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells
    • Kobayashi T, Mizuno H, Imayoshi I, Furusawa C, Shirahige K, et al. (2009) The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells. Genes and Dev 23 (16): 1870-1875.
    • (2009) Genes and Dev , vol.23 , Issue.16 , pp. 1870-1875
    • Kobayashi, T.1    Mizuno, H.2    Imayoshi, I.3    Furusawa, C.4    Shirahige, K.5
  • 35
    • 0037131389 scopus 로고    scopus 로고
    • "Stemness": transcriptional profiling of embryonic and adult stem cells
    • Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA, (2002) "Stemness": transcriptional profiling of embryonic and adult stem cells. Science 298 (5593): 597-600.
    • (2002) Science , vol.298 , Issue.5593 , pp. 597-600
    • Ramalho-Santos, M.1    Yoon, S.2    Matsuzaki, Y.3    Mulligan, R.C.4    Melton, D.A.5
  • 36
    • 25144525014 scopus 로고    scopus 로고
    • Core transcriptional regulatory circuitry in human embryonic stem cells
    • Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, et al. (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122 (6): 947-956.
    • (2005) Cell , vol.122 , Issue.6 , pp. 947-956
    • Boyer, L.A.1    Lee, T.I.2    Cole, M.F.3    Johnstone, S.E.4    Levine, S.S.5
  • 37
    • 40249093059 scopus 로고    scopus 로고
    • A core Klf circuitry regulates self-renewal of embryonic stem cells
    • Jiang J, Chan YS, Loh YH, Cai J, Tong GQ, et al. (2008) A core Klf circuitry regulates self-renewal of embryonic stem cells. Nat Cell Biol 10 (3): 353-360.
    • (2008) Nat Cell Biol , vol.10 , Issue.3 , pp. 353-360
    • Jiang, J.1    Chan, Y.S.2    Loh, Y.H.3    Cai, J.4    Tong, G.Q.5
  • 38
    • 33645381936 scopus 로고    scopus 로고
    • The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
    • Loh YH, Wu Q, Chew JL, Vega VB, Zhang W, et al. (2006) The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nature Genetics 38 (4): 431-440.
    • (2006) Nature Genetics , vol.38 , Issue.4 , pp. 431-440
    • Loh, Y.H.1    Wu, Q.2    Chew, J.L.3    Vega, V.B.4    Zhang, W.5
  • 39
    • 44649117905 scopus 로고    scopus 로고
    • Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
    • Chen X, Xu H, Yuan P, Fang F, Huss M, et al. (2008) Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133 (6): 1106-1117.
    • (2008) Cell , vol.133 , Issue.6 , pp. 1106-1117
    • Chen, X.1    Xu, H.2    Yuan, P.3    Fang, F.4    Huss, M.5
  • 40
    • 34249914507 scopus 로고    scopus 로고
    • Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment
    • Walker E, Ohishi M, Davey RE, Zhang W, Cassar PA, et al. (2007) Prediction and testing of novel transcriptional networks regulating embryonic stem cell self-renewal and commitment. Cell Stem Cell 1 (1): 71-86.
    • (2007) Cell Stem Cell , vol.1 , Issue.1 , pp. 71-86
    • Walker, E.1    Ohishi, M.2    Davey, R.E.3    Zhang, W.4    Cassar, P.A.5
  • 41
    • 33845628507 scopus 로고    scopus 로고
    • A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal
    • Pan G, Li J, Zhou Y, Zheng H, Pei D, (2006) A negative feedback loop of transcription factors that controls stem cell pluripotency and self-renewal. FASEB J 20 (10): 1730-1732.
    • (2006) FASEB J , vol.20 , Issue.10 , pp. 1730-1732
    • Pan, G.1    Li, J.2    Zhou, Y.3    Zheng, H.4    Pei, D.5
  • 42
    • 70849084547 scopus 로고    scopus 로고
    • Cell state switching and dynamical patterning modules: complementary mediators of plasticity in development and evolution
    • Newman SA, Bhat R, Mezentseva NV, (2009) Cell state switching and dynamical patterning modules: complementary mediators of plasticity in development and evolution, J. Biosci 34: 553-572.
    • (2009) J Biosci , vol.34 , pp. 553-572
    • Newman, S.A.1    Bhat, R.2    Mezentseva, N.V.3
  • 43
    • 70349325798 scopus 로고    scopus 로고
    • Uncovering Early Response of Gene Regulatory Networks in ESCs by Systematic Induction of Transcription Factors
    • Nishiyama A, Xin L, Sharov AA, Thomas M, Mowrer G, et al. (2009) Uncovering Early Response of Gene Regulatory Networks in ESCs by Systematic Induction of Transcription Factors, Cell Stem Cell 5: 420-433.
    • (2009) Cell Stem Cell , vol.5 , pp. 420-433
    • Nishiyama, A.1    Xin, L.2    Sharov, A.A.3    Thomas, M.4    Mowrer, G.5
  • 44
    • 34347394540 scopus 로고    scopus 로고
    • LIF-mediated control of embryonic stem cell self-renewal emerges due to an autoregulatory loop
    • Davey RE, Onishi K, Mahdavi A, Zandstra PW, (2007) LIF-mediated control of embryonic stem cell self-renewal emerges due to an autoregulatory loop. FASEB J 21: 2020-2032.
    • (2007) FASEB J , vol.21 , pp. 2020-2032
    • Davey, R.E.1    Onishi, K.2    Mahdavi, A.3    Zandstra, P.W.4
  • 45
    • 54949151933 scopus 로고    scopus 로고
    • Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition.
    • Kageyama R, Ohtsuka T, Shimojo H, Imayoshi I, (2008) Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition.Nature neurosci. 11: 1247-51.
    • (2008) Nature Neurosci , vol.11 , pp. 1247-1251
    • Kageyama, R.1    Ohtsuka, T.2    Shimojo, H.3    Imayoshi, I.4
  • 46
    • 0037174669 scopus 로고    scopus 로고
    • Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop
    • Hirata H, Yoshiura S, Ohtsuka T, Bessho Y, Harada T, et al. (2002) Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop. Science 298: 840-3.
    • (2002) Science , vol.298 , pp. 840-843
    • Hirata, H.1    Yoshiura, S.2    Ohtsuka, T.3    Bessho, Y.4    Harada, T.5
  • 47
    • 77950207188 scopus 로고    scopus 로고
    • Preimplantation development of mouse: a view from cellular behavior
    • Fujimori T, (2010) Preimplantation development of mouse: a view from cellular behavior. Dev Growth Differ 52 (3): 253-262.
    • (2010) Dev Growth Differ , vol.52 , Issue.3 , pp. 253-262
    • Fujimori, T.1
  • 48
    • 6044270503 scopus 로고    scopus 로고
    • The origin of hematopietic cell type diversity
    • Hoang T, (2004) The origin of hematopietic cell type diversity, Oncogene 23: 7188-7198/.
    • (2004) Oncogene , vol.23 , pp. 7188-7198
    • Hoang, T.1
  • 49
    • 0036124174 scopus 로고    scopus 로고
    • Neural stem cells and regulation of cell number
    • Sommer L, Rao M, (2002) Neural stem cells and regulation of cell number. Progress in Neurobiology 66: 1-18.
    • (2002) Progress in Neurobiology , vol.66 , pp. 1-18
    • Sommer, L.1    Rao, M.2
  • 51
    • 68749116324 scopus 로고    scopus 로고
    • Cell-cell interaction networks regulate blood stem and progenitor cell fate
    • Kirouac DC, Madlambayan GJ, Yu M, Sykes EA, Ito C, et al. (2009) Cell-cell interaction networks regulate blood stem and progenitor cell fate. Mol. Syst. Biol. 5: 293.
    • (2009) Mol. Syst. Biol , vol.5 , pp. 293
    • Kirouac, D.C.1    Madlambayan, G.J.2    Yu, M.3    Sykes, E.A.4    Ito, C.5
  • 52
    • 70349419698 scopus 로고    scopus 로고
    • The 'stem cell' concept: Is it holding us back?
    • Lander AD, (2009) The 'stem cell' concept: Is it holding us back? Jour. Biol. 8: 70.
    • (2009) Jour. Biol , vol.8 , pp. 70
    • Lander, A.D.1
  • 53
    • 0015609281 scopus 로고
    • The logical analysis of continuous, non-linear biochemical control networks
    • Glass L, Kauffman SA, (1973) The logical analysis of continuous, non-linear biochemical control networks. J Theor Biol. 39 (1): 103-129.
    • (1973) J Theor Biol , vol.39 , Issue.1 , pp. 103-129
    • Glass, L.1    Kauffman, S.A.2
  • 54
    • 0025991216 scopus 로고
    • A connectionist model of development
    • Mjolsness E, Sharp DH, Reinitz J, (1991) A connectionist model of development. J Theor Biol 152 (4): 429-453.
    • (1991) J Theor Biol , vol.152 , Issue.4 , pp. 429-453
    • Mjolsness, E.1    Sharp, D.H.2    Reinitz, J.3
  • 55
    • 0035051919 scopus 로고    scopus 로고
    • Phenotypic and dynamical transitions in model genetic networks I.
    • Salazar-Ciudad I, Newman SA, Sole RV, (2001) Phenotypic and dynamical transitions in model genetic networks I.Evo & Dev 3 (2): 84-94.
    • (2001) Evo & Dev , vol.3 , Issue.2 , pp. 84-94
    • Salazar-Ciudad, I.1    Newman, S.A.2    Sole, R.V.3


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