Inhibition of mercapturic acid pathway-mediated disposal of 4-hydroxynonenal causes complete and sustained remission of human cancer xenografts in nude mice

Indian Journal of Experimental Biology

Volumn 49, Issue 11, 2011, Pages 817-825

  Kumar, Sushil ^a,b   Kokate, Rutika A ^a   Sahu, Mukesh ^a   Chaudhary, Pankaj ^a   Sharma, Rajendra ^a   Awasthi, Sanjay ^a,c   Awasthi, Yogesh C ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^b UNIVERSITY OF COLORADO   (United States)

^c CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

4 Hydroxynonenal; Cancer; Chemo prevention; Glutathione S transferase; Mercapturic acid pathway; RLIP76,Xenobiotics

Indexed keywords

4 HYDROXYNONENAL; 4-HYDROXY-2-NONENAL; ABC TRANSPORTER; ACETYLCYSTEINE; ALDEHYDE; CARCINOGEN; GLUTATHIONE TRANSFERASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RALBP1 PROTEIN, HUMAN; XENOBIOTIC AGENT;

ANIMAL; CANCER TRANSPLANTATION; CHEMOPROPHYLAXIS; DRUG ANTAGONISM; ENZYMOLOGY; HUMAN; METABOLISM; MOUSE; NEOPLASM; NUDE MOUSE; REMISSION; REVIEW;

ACETYLCYSTEINE; ALDEHYDES; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CARCINOGENS, ENVIRONMENTAL; CHEMOPREVENTION; GLUTATHIONE TRANSFERASE; GTPASE-ACTIVATING PROTEINS; HUMANS; METABOLIC NETWORKS AND PATHWAYS; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOPLASMS; REMISSION INDUCTION; XENOBIOTICS;

MUS; MUS MUSCULUS;

EID: 80355141493     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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