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Volumn 301, Issue 5, 2011, Pages

Sepiapterin enhances angiogenesis and functional recovery in mice after myocardial infarction

Author keywords

Left ventricular; Nitric oxide synthase; Tetrahydrobiopterin

Indexed keywords

3 NITROTYROSINE; DIHYDROBIOPTERIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; INDUCIBLE NITRIC OXIDE SYNTHASE; NEURONAL NITRIC OXIDE SYNTHASE; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; SEPIAPTERIN; TETRAHYDROBIOPTERIN;

EID: 80355134456     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00525.2011     Document Type: Article
Times cited : (21)

References (57)
  • 1
    • 0037173019 scopus 로고    scopus 로고
    • Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes
    • Ashley EA, Sears CE, Bryant SM, Watkins HC, Casadei B. Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes. Circulation 105: 3011-3016, 2002.
    • (2002) Circulation , vol.105 , pp. 3011-3016
    • Ashley, E.A.1    Sears, C.E.2    Bryant, S.M.3    Watkins, H.C.4    Casadei, B.5
  • 3
    • 0033587530 scopus 로고    scopus 로고
    • Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: Role of enhanced vascular superoxide production
    • Bauersachs J, Bouloumie A, Fraccarollo D, Hu K, Busse R, Ertl G. Endothelial dysfunction in chronic myocardial infarction despite increased vascular endothelial nitric oxide synthase and soluble guanylate cyclase expression: role of enhanced vascular superoxide production. Circulation 100: 292-298, 1999.
    • (1999) Circulation , vol.100 , pp. 292-298
    • Bauersachs, J.1    Bouloumie, A.2    Fraccarollo, D.3    Hu, K.4    Busse, R.5    Ertl, G.6
  • 4
    • 6444242933 scopus 로고    scopus 로고
    • Role of myocardial neuronal nitric oxide synthase-derived nitric oxide in beta-adrenergic hyporesponsiveness after myocardial infarction-induced heart failure in rat
    • Bendall JK, Damy T, Ratajczak P, Loyer X, Monceau V, Marty I, Milliez P, Robidel E, Marotte F, Samuel JL, Heymes C. Role of myocardial neuronal nitric oxide synthase-derived nitric oxide in beta-adrenergic hyporesponsiveness after myocardial infarction-induced heart failure in rat. Circulation 110: 2368-2375, 2004.
    • (2004) Circulation , vol.110 , pp. 2368-2375
    • Bendall, J.K.1    Damy, T.2    Ratajczak, P.3    Loyer, X.4    Monceau, V.5    Marty, I.6    Milliez, P.7    Robidel, E.8    Marotte, F.9    Samuel, J.L.10    Heymes, C.11
  • 5
    • 0035199811 scopus 로고    scopus 로고
    • Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: An overview of a decade of research
    • Bolli R. Cardioprotective function of inducible nitric oxide synthase and role of nitric oxide in myocardial ischemia and preconditioning: an overview of a decade of research. J Mol Cell Cardiol 33: 1897-1918, 2001.
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 1897-1918
    • Bolli, R.1
  • 6
    • 0030777615 scopus 로고    scopus 로고
    • The protective effect of late preconditioning against myocardial stunning in conscious rabbits is mediated by nitric oxide synthase. Evidence that nitric oxide acts both as a trigger and as a mediator of the late phase of ischemic preconditioning
    • Bolli R, Manchikalapudi S, Tang XL, Takano H, Qiu Y, Guo Y, Zhang Q, Jadoon AK. The protective effect of late preconditioning against myocardial stunning in conscious rabbits is mediated by nitric oxide synthase. Evidence that nitric oxide acts both as a trigger and as a mediator of the late phase of ischemic preconditioning. Circ Res 81: 1094-1107, 1997.
    • (1997) Circ Res , vol.81 , pp. 1094-1107
    • Bolli, R.1    Manchikalapudi, S.2    Tang, X.L.3    Takano, H.4    Qiu, Y.5    Guo, Y.6    Zhang, Q.7    Jadoon, A.K.8
  • 7
    • 70349730049 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase protects against myocardial infarction-induced ventricular arrhythmia and mortality in mice
    • Burger DE, Lu X, Lei M, Xiang FL, Hammoud L, Jiang M, Wang H, Jones DL, Sims SM, Feng Q. Neuronal nitric oxide synthase protects against myocardial infarction-induced ventricular arrhythmia and mortality in mice. Circulation 120: 1345-1354, 2009.
    • (2009) Circulation , vol.120 , pp. 1345-1354
    • Burger, D.E.1    Lu, X.2    Lei, M.3    Xiang, F.L.4    Hammoud, L.5    Jiang, M.6    Wang, H.7    Jones, D.L.8    Sims, S.M.9    Feng, Q.10
  • 9
    • 33750618928 scopus 로고    scopus 로고
    • The emerging role of neuronal nitric oxide synthase in the regulation of myocardial function
    • Casadei B. The emerging role of neuronal nitric oxide synthase in the regulation of myocardial function. Exp Physiol 91: 943-955, 2006.
    • (2006) Exp Physiol , vol.91 , pp. 943-955
    • Casadei, B.1
  • 11
    • 33644875411 scopus 로고    scopus 로고
    • nNOS gene deletion exacerbates pathological left ventricular remodeling and functional deterioration after myocardial infarction
    • Dawson D, Lygate CA, Zhang MH, Hulbert K, Neubauer S, Casadei B. nNOS gene deletion exacerbates pathological left ventricular remodeling and functional deterioration after myocardial infarction. Circulation 112: 3729-3737, 2005.
    • (2005) Circulation , vol.112 , pp. 3729-3737
    • Dawson, D.1    Lygate, C.A.2    Zhang, M.H.3    Hulbert, K.4    Neubauer, S.5    Casadei, B.6
  • 12
    • 0032192130 scopus 로고    scopus 로고
    • Expression, activity and functional significance of inducible nitric oxide synthase in the failing human heart
    • Drexler H, Kastner S, Strobel A, Studer R, Brodde OE, Hasenfuss G. Expression, activity and functional significance of inducible nitric oxide synthase in the failing human heart. J Am Coll Cardiol 32: 955-963, 1998.
    • (1998) J Am Coll Cardiol , vol.32 , pp. 955-963
    • Drexler, H.1    Kastner, S.2    Strobel, A.3    Studer, R.4    Brodde, O.E.5    Hasenfuss, G.6
  • 13
    • 70749095115 scopus 로고    scopus 로고
    • Enhanced mesenchymal cell engraftment by IGF-1 improves left ventricular function in rats undergoing myocardial infarction
    • Enoki C, Otani H, Sato D, Okada T, Hattori R, Imamura H. Enhanced mesenchymal cell engraftment by IGF-1 improves left ventricular function in rats undergoing myocardial infarction. Int J Cardiol 138: 9-18, 2010.
    • (2010) Int J Cardiol , vol.138 , pp. 9-18
    • Enoki, C.1    Otani, H.2    Sato, D.3    Okada, T.4    Hattori, R.5    Imamura, H.6
  • 14
    • 0035822692 scopus 로고    scopus 로고
    • Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocardial infarction in mice
    • Feng Q, Lu X, Jones DL, Shen J, Arnold JM. Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocardial infarction in mice. Circulation 104: 700-704, 2001.
    • (2001) Circulation , vol.104 , pp. 700-704
    • Feng, Q.1    Lu, X.2    Jones, D.L.3    Shen, J.4    Arnold, J.M.5
  • 16
    • 35348963021 scopus 로고    scopus 로고
    • Borderzone contractile dysfunction is transiently attenuated and left ventricular structural remodeling is markedly reduced following reperfused myocardial infarction in inducible nitric oxide synthase knockout mice
    • Gilson WD, Epstein FH, Yang Z, Xu Y, Prasad KM, Toufektsian MC, Laubach VE, French BA. Borderzone contractile dysfunction is transiently attenuated and left ventricular structural remodeling is markedly reduced following reperfused myocardial infarction in inducible nitric oxide synthase knockout mice. J Am Coll Cardiol 50: 1799-1807, 2007.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1799-1807
    • Gilson, W.D.1    Epstein, F.H.2    Yang, Z.3    Xu, Y.4    Prasad, K.M.5    Toufektsian, M.C.6    Laubach, V.E.7    French, B.A.8
  • 21
    • 0041828198 scopus 로고    scopus 로고
    • Expression of inducible nitric oxide synthase, left ventricular function and remodeling in Dahl salt-sensitive hypertensive rats
    • Horinaka S, Kobayashi N, Mori Y, Yagi H, Onoda M, Matsuoka H. Expression of inducible nitric oxide synthase, left ventricular function and remodeling in Dahl salt-sensitive hypertensive rats. Int J Cardiol 91: 25-35, 2003.
    • (2003) Int J Cardiol , vol.91 , pp. 25-35
    • Horinaka, S.1    Kobayashi, N.2    Mori, Y.3    Yagi, H.4    Onoda, M.5    Matsuoka, H.6
  • 22
    • 0036023620 scopus 로고    scopus 로고
    • The importance of manganese superoxide dismutase in delayed preconditioning: Involvement of reactive oxygen species and cytokines
    • Hoshida S, Yamashita N, Otsu K, Hori M. The importance of manganese superoxide dismutase in delayed preconditioning: involvement of reactive oxygen species and cytokines. Cardiovasc Res 55: 495-505, 2002.
    • (2002) Cardiovasc Res , vol.55 , pp. 495-505
    • Hoshida, S.1    Yamashita, N.2    Otsu, K.3    Hori, M.4
  • 24
    • 79960711345 scopus 로고    scopus 로고
    • Inhibition of Nitric Oxide Synthase Uncoupling by Sepiapterin Improves Left Ventricular Function in Streptozotocin-induced Diabetic Mice
    • Jo H, Otani H, Jo F, Shimazu T, Okazaki T, Yoshioka K, Fujita M, Kosaki A, Iwasaka T. Inhibition of Nitric Oxide Synthase Uncoupling by Sepiapterin Improves Left Ventricular Function in Streptozotocin-induced Diabetic Mice. Clin Exp Pharmacol Physiol 38: 485-493, 2011.
    • (2011) Clin Exp Pharmacol Physiol , vol.38 , pp. 485-493
    • Jo, H.1    Otani, H.2    Jo, F.3    Shimazu, T.4    Okazaki, T.5    Yoshioka, K.6    Fujita, M.7    Kosaki, A.8    Iwasaka, T.9
  • 28
  • 31
    • 38849108758 scopus 로고    scopus 로고
    • Does nitric oxide modulate cardiac ryanodine receptor function? Implications for excitation-contraction coupling
    • Lim G, Venetucci L, Eisner DA, Casadei B. Does nitric oxide modulate cardiac ryanodine receptor function? Implications for excitation-contraction coupling. Cardiovasc Res 77: 256-264, 2008.
    • (2008) Cardiovasc Res , vol.77 , pp. 256-264
    • Lim, G.1    Venetucci, L.2    Eisner, D.A.3    Casadei, B.4
  • 34
    • 50449108911 scopus 로고    scopus 로고
    • Beneficial effects of exogenous tetrahydrobiopterin on left ventricular remodeling after myocardial infarction in rats: The possible role of oxidative stress caused by uncoupled endothelial nitric oxide synthase
    • Masano T, Kawashima S, Toh R, Satomi-Kobayashi S, Shinohara M, Takaya T, Sasaki N, Takeda M, Tawa H, Yamashita T, Yokoyama M, Hirata K. Beneficial effects of exogenous tetrahydrobiopterin on left ventricular remodeling after myocardial infarction in rats: the possible role of oxidative stress caused by uncoupled endothelial nitric oxide synthase. Circ J 72: 1512-1519, 2008.
    • (2008) Circ J , vol.72 , pp. 1512-1519
    • Masano, T.1    Kawashima, S.2    Toh, R.3    Satomi-Kobayashi, S.4    Shinohara, M.5    Takaya, T.6    Sasaki, N.7    Takeda, M.8    Tawa, H.9    Yamashita, T.10    Yokoyama, M.11    Hirata, K.12
  • 35
    • 0042917516 scopus 로고    scopus 로고
    • Nitric oxide and cardiac function: Ten years after, and continuing
    • Massion PB, Feron O, Dessy C, Balligand JL. Nitric oxide and cardiac function: ten years after, and continuing. Circ Res 93: 388-398, 2003.
    • (2003) Circ Res , vol.93 , pp. 388-398
    • Massion, P.B.1    Feron, O.2    Dessy, C.3    Balligand, J.L.4
  • 36
    • 0030694038 scopus 로고    scopus 로고
    • Biosynthesis and action of nitric oxide in mammalian cells
    • Mayer B, Hemmens B. Biosynthesis and action of nitric oxide in mammalian cells. Trends Biochem Sci 22: 477-481, 1997.
    • (1997) Trends Biochem Sci , vol.22 , pp. 477-481
    • Mayer, B.1    Hemmens, B.2
  • 37
    • 79551582218 scopus 로고    scopus 로고
    • Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart
    • Okazaki T, Otani H, Shimazu T, Yoshioka K, Fujita M, Katano T, Ito S, Iwasaka T. Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart. J Mol Cell Cardiol 50: 534-544, 2011.
    • (2011) J Mol Cell Cardiol , vol.50 , pp. 534-544
    • Okazaki, T.1    Otani, H.2    Shimazu, T.3    Yoshioka, K.4    Fujita, M.5    Katano, T.6    Ito, S.7    Iwasaka, T.8
  • 38
    • 37549011356 scopus 로고    scopus 로고
    • Ischemic preconditioning: From molecular mechanisms to therapeutic opportunities
    • Otani H. Ischemic preconditioning: from molecular mechanisms to therapeutic opportunities. Antioxid Redox Signal 10: 207-247, 2008.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 207-247
    • Otani, H.1
  • 39
    • 67650239426 scopus 로고    scopus 로고
    • The role of nitric oxide in myocardial repair and remodeling
    • Otani H. The role of nitric oxide in myocardial repair and remodeling. Antioxid Redox Signal 11: 1913-1928, 2009.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 1913-1928
    • Otani, H.1
  • 41
    • 66749102277 scopus 로고    scopus 로고
    • Sepiapterin decreases acute rejection and apop-tosis in cardiac transplants independently of changes in nitric oxide and inducible nitric-oxide synthase dimerization
    • Pieper GM, Ionova IA, Cooley BC, Migrino RQ, Khanna AK, Whit-sett J, Vasquez-Vivar J. Sepiapterin decreases acute rejection and apop-tosis in cardiac transplants independently of changes in nitric oxide and inducible nitric-oxide synthase dimerization. J Pharmacol Exp Ther 329: 890-899, 2009.
    • (2009) J Pharmacol Exp Ther , vol.329 , pp. 890-899
    • Pieper, G.M.1    Ionova, I.A.2    Cooley, B.C.3    Migrino, R.Q.4    Khanna, A.K.5    Whit-Sett, J.6    Vasquez-Vivar, J.7
  • 42
    • 0033592305 scopus 로고    scopus 로고
    • Improvement of endocardial and vascular endothelial function on myocardial performance by captopril treatment in postinfarct rat hearts
    • Qi XL, Stewart DJ, Gosselin H, Azad A, Picard P, Andries L, Sys SU, Brutsaert DL, Rouleau JL. Improvement of endocardial and vascular endothelial function on myocardial performance by captopril treatment in postinfarct rat hearts. Circulation 100: 1338-1345, 1999.
    • (1999) Circulation , vol.100 , pp. 1338-1345
    • Qi, X.L.1    Stewart, D.J.2    Gosselin, H.3    Azad, A.4    Picard, P.5    Andries, L.6    Sys, S.U.7    Brutsaert, D.L.8    Rouleau, J.L.9
  • 44
    • 0035903250 scopus 로고    scopus 로고
    • Mice lacking inducible nitric oxide synthase have improved left ventricular contractile function and reduced apoptotic cell death late after myocardial infarction
    • Sam F, Sawyer DB, Xie Z, Chang DL, Ngoy S, Brenner DA, Siwik DA, Singh K, Apstein CS, Colucci WS. Mice lacking inducible nitric oxide synthase have improved left ventricular contractile function and reduced apoptotic cell death late after myocardial infarction. Circ Res 89: 351-356, 2001.
    • (2001) Circ Res , vol.89 , pp. 351-356
    • Sam, F.1    Sawyer, D.B.2    Xie, Z.3    Chang, D.L.4    Ngoy, S.5    Brenner, D.A.6    Siwik, D.A.7    Singh, K.8    Apstein, C.S.9    Colucci, W.S.10
  • 48
    • 0035805555 scopus 로고    scopus 로고
    • Oxygen reduction by nitric-oxide synthases
    • Stuehr D, Pou S, Rosen GM. Oxygen reduction by nitric-oxide synthases. J Biol Chem 276: 14533-14536, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 14533-14536
    • Stuehr, D.1    Pou, S.2    Rosen, G.M.3
  • 50
    • 0027305213 scopus 로고
    • Analysis of 6R- and 6S-tetrahydrobiopterin and other pterins by reversed-phase ion-pair liquid-chromatography with fluorimet-ric detection by post-column sodium nitrite oxidation
    • Tani Y, Ohno T. Analysis of 6R- and 6S-tetrahydrobiopterin and other pterins by reversed-phase ion-pair liquid-chromatography with fluorimet-ric detection by post-column sodium nitrite oxidation. J Chromatogr 617: 249-255, 1993.
    • (1993) J Chromatogr , vol.617 , pp. 249-255
    • Tani, Y.1    Ohno, T.2
  • 51
    • 34247135353 scopus 로고    scopus 로고
    • +/~) gene knockout leads to the disruption of VEGF-mediated signaling through the nitric oxide/heme oxygenase pathway in ischemic preconditioned myocardium
    • +/~) gene knockout leads to the disruption of VEGF-mediated signaling through the nitric oxide/heme oxygenase pathway in ischemic preconditioned myocardium. Free Radic Biol Med 42: 1487-1495, 2007.
    • (2007) Free Radic Biol Med , vol.42 , pp. 1487-1495
    • Thirunavukkarasu, M.1    Juhasz, B.2    Zhan, L.3    Menon, V.P.4    Tosaki, A.5    Otani, H.6    Maulik, N.7
  • 52
    • 0034176921 scopus 로고    scopus 로고
    • Tetrahydrobiopterin biosynthesis, regeneration and functions
    • Thony B, Auerbach G, Blau N. Tetrahydrobiopterin biosynthesis, regeneration and functions. Biochem J 347: 1-16, 2000.
    • (2000) Biochem J , vol.347 , pp. 1-16
    • Thony, B.1    Auerbach, G.2    Blau, N.3
  • 54
    • 68049129864 scopus 로고    scopus 로고
    • In vivo activation of AMP-activated protein kinase attenuates diabetes-enhanced degradation of GTP cyclohydrolase I
    • Wang S, Xu J, Song P, Viollet B, Zou MH. In vivo activation of AMP-activated protein kinase attenuates diabetes-enhanced degradation of GTP cyclohydrolase I. Diabetes 58: 1893-1901, 2009.
    • (2009) Diabetes , vol.58 , pp. 1893-1901
    • Wang, S.1    Xu, J.2    Song, P.3    Viollet, B.4    Zou, M.H.5
  • 55
    • 0035671967 scopus 로고    scopus 로고
    • Decreased nitric oxide availability in normotensive and hypertensive rats with failing hearts after myocardial infarction
    • Wiemer G, Itter G, Malinski T, Linz W. Decreased nitric oxide availability in normotensive and hypertensive rats with failing hearts after myocardial infarction. Hypertension 38: 1367-1371, 2001.
    • (2001) Hypertension , vol.38 , pp. 1367-1371
    • Wiemer, G.1    Itter, G.2    Malinski, T.3    Linz, W.4
  • 56
    • 34548134851 scopus 로고    scopus 로고
    • Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus
    • Xu J, Wu Y, Song P, Zhang M, Wang S, Zou MH. Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus. Circulation 116: 944-953, 2007.
    • (2007) Circulation , vol.116 , pp. 944-953
    • Xu, J.1    Wu, Y.2    Song, P.3    Zhang, M.4    Wang, S.5    Zou, M.H.6


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