Caveolin-1 inhibits membrane-type 1 matrix metalloproteinase activity

Journal of Biochemistry and Molecular Biology

Volumn 41, Issue 12, 2008, Pages 858-862

  Kim, Hye Nan ^a   Chung, Hye Shin ^a  

^a Hannam University   (South Korea)

Author keywords

Caveolin 1; Cell migration; Collagen degradation; MMP 2; MT1 MMP

Indexed keywords

EID: 58149354851     PISSN: 12258687     EISSN: 02191024     Source Type: Journal    
DOI: 10.5483/bmbrep.2008.41.12.858     Document Type: Article

References (20)

1. Nagase, H. and Woessner, J.F., Jr. (1999) Matrix metalloproteinases.J. Biol. Chem. 274, 21491-21494.
2. Sato, H., Takino, T., Okada, Y., Cao, J., Shinagawa, A., Yamamoto, E. and Seiki, M. (1994) A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature 370, 61-65.
3. Egeblad, M. and Werb, Z. (2002) New functions for the matrix metalloproteinases in cancer progression. Nat. Rev. Cancer 2, 161-174.
4. Yana, I. and Weiss, S.J. (2000) Regulation of membrane type-1 matrix metalloproteinase activation by proprotein convertases. Mol. Biol. Cell 11, 2387-2401.
5. Rozanov, D.V., Ghebrehiwet, B., Ratnikov, B., Monosov, E.Z., Deryugina, E.I. and Strongin, A.Y, (2002) The cytoplasmic tail peptide sequence of membrane type-1 matrix metalloproteinase (MT1-MMP) directly binds to gC1qR, a compartment-specific chaperone-like regulatory protein. FEBS. Lett. 527, 51-57.
6. Cao, J., Kozarekar, P., Pavlaki, M., Chiarelli, C., Bahou, W.F. and Zucker, S. (2004) Distinct roles for the catalytic and hemopexin domains of membrane type 1-matrix metalloproteinase in substrate degradation and cell migration. J. Biol. Chem. 279, 14129-14139.
7. Butler, G.S., Butler, M.J., Atkinson, S.J., Will, H., Tamura, T., Schade van Westrum, S., Crabbe, T., Clements, J., d' Ortho, M.P. and Murphy, G. (1998) The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study. J. Biol. Chem. 273, 871-880.
8. Stanton, H., Gavrilovic, J., Atkinson, S.J., d' Ortho, M.P., Yamada, K.M., Zardi, L. and Murphy, G. (1998) The activation of ProMMP-2 (gelatinase A) by HT1080 fibrosarcoma cells is promoted by culture on a fibronectin substrate and is concomitant with an increase in processing of MT1-MMP (MMP-14) to a 45 kDa form. J. Cell Set. 111 (Pt 18), 2789-2798.
9. Annabi, B., Lachambre, M., Bousquet-Gagnon, N., Page, M., Gingras, D. and Beliveau, R. (2001) Localization of membrane-type 1 matrix metalloproteinase in caveolae membrane domains. Biochem. J. 353, 547-553.
10. Patel, H.H., Murray, F. and Insel, P.A. (2008) Caveolae as organizers of pharmacologically relevant signal transduction molecules. Annu. Rev. Pharmacol. Toxicol. 48, 359-391.
11. Krajewska, W.M. and Maslowska, I. (2004) Caveolins: structure and function in signal transduction. Cell Mol. Biol. Lett. 9, 195-220.
12. Razani, B., Schlegel, A. and Lisanti, M.P. (2000) Caveolin proteins in signaling, oncogenic transformation and muscular dystrophy. J. Cell Sci. 113 (P112), 2103-2109.
13. Liu, P., Rudick, M. and Anderson, R.G. (2002) Multiple functions of caveolin-1. j. Biol. Chem. 277, 41295-41298.
14. Labrecque, L., Nyalendo, C., Langlois, S., Durocher, Y., Roghi, C., Murphy, G., Gingras, D. and Beliveau, R. (2004) Src-mediated tyrosine phosphorylation of caveolin-1 induces its association with membrane type 1 matrix metalloproteinase. J. Biol. Chem. 279, 52132-52140.
15. Atkinson, S.J., English, J.L., Holway, N. and Murphy, G. (2004) Cellular cholesterol regulates MT1 MMP dependent activation of MMP 2 via MEK-1 in HT1080 fibrosarcoma cells. FEBS. Lett. 566, 65-70.
16. Rozanov, D.V., Deryugina, E.I., Monosov, E.Z., Marchenko, N.D. and Strongin, A.Y. (2004) Aberrant, persistent inclusion into lipid rafts limits the tumorigenic function of membrane type-1 matrix metalloproteinase in malignant cells. Exp. Cell Res. 293, 81-95.
17. Strongin, A.Y., Collier, I., Bannikov, G., Marmer, B.L., Grant, G.A. and Goldberg, G.I. (1995) Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease. J. Biol. Chem. 270, 5331-5338.
18. Holmbeck, K., Bianco, P., Caterina, J., Yamada, S., Kromer, M., Kuznetsov, S.A., Mankani, M., Robey, P.G., Poole, A.R., Pidoux, I., Ward, J.M. and Birkedal-Hansen, H. (1999) MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover. Cell 99, 81-92.
19. Itoh, Y., Takamura, A., Ito, N., Maru, Y., Sato, H., Suenaga, N., Aoki, T. and Seiki, M. (2001) Homophilic complex formation of MT1-MMP facilitates proMMP-2 activation on the cell surface and promotes tumor cell invasion. EMBO J. 20, 4782-4793.
20. Strongin, A.Y., Marmer, B.L., Grant, G.A. and Goldberg, G.I. (1993) Plasma membrane-dependent activation of the 72-kDa type IV collagenase is prevented by complex formation with TlMP-2. J. Biol. Chem. 268, 14033-14039.