T cell receptor signal initiation induced by low-grade stimulation requires the cooperation of lat in human T cells

PLoS ONE

Volumn 5, Issue 11, 2010, Pages

  Dong, Shen ^a,b   Corre, Béatrice ^a,b   Nika, Konstantina ^c   Pellegrini, Sandra ^a,b   Michel, Frédérique ^a,b  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LINKER FOR ACTIVATION OF T LYMPHOCYTE PROTEIN; LYMPHOCYTE RECEPTOR; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE FYN; PROTEIN KINASE LCK; PROTEIN KINASE ZAP 70; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR XI CHAIN; TYROSINE; UNCLASSIFIED DRUG; FYN PROTEIN, HUMAN; LAT PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; GENE SILENCING; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE TRANSFORMATION; LYMPHOID CELL LINE; NUCLEOTIDE SEQUENCE; PROTEIN ANALYSIS; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UNINDEXED SEQUENCE; CELL CULTURE; CYTOLOGY; ENZYME SPECIFICITY; GENETICS; IMMUNOBLOTTING; IMMUNOLOGY; METABOLISM; PHOSPHORYLATION; T LYMPHOCYTE; TUMOR CELL LINE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CD4-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; CELLS, CULTURED; HUMANS; IMMUNOBLOTTING; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE PROTEINS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-FYN; RECEPTORS, ANTIGEN, T-CELL; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; T-LYMPHOCYTES; TYROSINE;

EID: 78649794391     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015114     Document Type: Article

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