IGF-I contributes to glucose homeostasis in the Berlin Fat Mouse Inbred line

Growth Factors

Volumn 29, Issue 6, 2011, Pages 298-309

  Schäfer, Nadine ^a   Wagener, Asja ^a   Hantschel, Claudia ^a   Mauel, Susanne ^b   Gruber, Achim D ^b   Brockmann, Gudrun A ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Diabetes; Glucose; Insulin like growth factor binding protein; Obesity; Splice variant

Indexed keywords

GROWTH HORMONE RECEPTOR; INSULIN; PROLACTIN RECEPTOR; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BERLIN FAT MOUSE INBRED LINE; DIABETES MELLITUS; DIET; DOWN REGULATION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; LIVER; MALE; MOUSE; MOUSE STRAIN; MUSCLE; NONHUMAN; PANCREAS; PRIORITY JOURNAL;

ADIPOSE TISSUE; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS; DIET, HIGH-FAT; GLUCOSE; HOMEOSTASIS; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR BINDING PROTEINS; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OBESITY;

MUS; STEATOMYS PRATENSIS;

EID: 80155198706     PISSN: 08977194     EISSN: 10292292     Source Type: Journal    
DOI: 10.3109/08977194.2011.625026     Document Type: Article

References (43)

1. Adamo ML,MaX, Ackert-Bicknell CL, Donahue LR, Beamer WG, Rosen CJ. 2006. Genetic increase in serum insulin-like growth factor-I (IGF-I) in C3H/HeJ compared with C57BL/6J mice is associated with increased transcription from the IGF-I exon 2 promoter. Endocrinology 147:2944-2955 (Pubitemid 43764630)
2. Ajuwon KM, Kuske JL, Ragland D, Adeola O, Hancock DL, Anderson DB, Spurlock ME. 2003. The regulation of IGF-1 by leptin in the pig is tissue specific and independent of changes in growth hormone. J Nutr Biochem 14:522-530 (Pubitemid 37162651)
3. Alexandrides T, Moses AC, Smith RJ. 1989. Developmental expression of receptors for insulin, insulin-like growth factor I (IGF-I), and IGF-II in rat skeletal muscle. Endocrinology 124: 1064-1076 (Pubitemid 19057106)
4. Boni-Schnetzler M, Schmid C, Meier PJ, Froesch ER. 1991. Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes. Am J Physiol 260:E846-E851
5. Boulware SD, Tamborlane WV, Rennert NJ, Gesundheit N, Sherwin RS. 1994. Comparison of the metabolic effects of recombinant human insulin-like growth factor-I and insulin. Dose-response relationships in healthy young and middle-aged adults. J Clin Invest 93:1131-1139
6. Frystyk J, Brick DJ, Gerweck AV, Utz AL, Miller KK. 2009. Bioactive insulin-like growth factor-I in obesity. J Clin Endocrinol Metab 94:3093-3097
7. Frystyk J, Vestbo E, Skjaerbaek C, Mogensen CE, Orskov H. 1995. Free insulin-like growth factors in human obesity. Metabolism 44:37-44
8. Hantschel C, Wagener A, Neuschl C, Teupser D, Brockmann GA. 2011. Features of the Metabolic Syndrome in the Berlin Fat Mouse as a Model for Human Obesity. Obes Facts 4
9. Heald AH, Kaushal K, Siddals KW, Rudenski AS, Anderson SG, Gibson JM. 2006. Insulin-like growth factor binding protein-2 (IGFBP-2) is a marker for the metabolic syndrome. Exp Clin Endocrinol Diabetes 114:371-376 (Pubitemid 44265569)
10. Jones JI, Clemmons DR. 1995. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 16:3-34
11. Kratzsch J, Blum WF, Schenker E, Keller E, Jahreis G, Haustein B, Ventz M, Rotzsch W. 1993. Measurement of insulin-like growth factor I (IGF-I) in normal adults, patients with liver cirrhosis and acromegaly: experience with a new competitive enzyme immunoassay. Exp Clin Endocrinol 101:144-149 (Pubitemid 23270622)
12. LeRoith D, Werner H, Beitner-Johnson D, Roberts CT, Jr. 1995. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr Rev 16:143-163
13. Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-408 (Pubitemid 34164012)
14. Loche S, Cappa M, Borrelli P, Faedda A, Crino A, Cella SG, Corda R, Muller EE, Pintor C. 1987. Reduced growth hormone response to growth hormone-releasing hormone in children with simple obesity: evidence for somatomedin-C mediated inhibition. Clin Endocrinol (Oxf) 27:145-153 (Pubitemid 17093746)
15. Maccario M, Ramunni J, Oleandri SE, Procopio M, Grottoli S, Rossetto R, Savio P, Aimaretti G, Camanni F, Ghigo E. 1999. Relationships between IGF-I and age, gender, body mass, fat distribution, metabolic and hormonal variables in obese patients. Int J Obes Relat Metab Disord 23:612-618 (Pubitemid 29276810)
16. Meyer CW, Wagener A, Rink N, Hantschel C, Heldmaier G, Klingenspor M, Brockmann GA. 2009. High energy digestion efficiency and altered lipid metabolism contribute to obesity in BFMI mice. Obesity (Silver Spring) 17:1988-1993
17. Moller DE, Yokota A, Caro JF, Flier JS. 1989. Tissue-specific expression of two alternatively spliced insulin receptor mRNAs in man. Mol Endocrinol 3:1263-1269 (Pubitemid 19210437)
18. Mosthaf L, Grako K, Dull TJ, Coussens L, Ullrich A, McClain DA. 1990. Functionally distinct insulin receptors generated by tissuespecific alternative splicing. EMBO J 9:2409-2413
19. Nam SY, Lee EJ, Kim KR, Cha BS, Song YD, Lim SK, Lee HC, Huh KB. 1997. Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone. Int J Obes Relat Metab Disord 21:355-359 (Pubitemid 27190186)
20. Nam SY,Marcus C. 2000. Growth hormone and adipocyte function in obesity. Horm Res 53(Suppl 1):87-97 (Pubitemid 30481327)
21. Neuschl C, Hantschel C, Wagener A, Schmitt AO, Illig T, Brockmann GA. 2010. A unique genetic defect on chromosome 3 is responsible for juvenile obesity in the Berlin Fat Mouse. Int J Obes (Lond) 34:1706-1714
22. Ohlsson C, Mohan S, Sjogren K, Tivesten A, Isgaard J, Isaksson O, Jansson JO, Svensson J. 2009. The role of liver-derived insulinlike growth factor-I. Endocr Rev 30:494-535
23. Pandini G, Frasca F, Mineo R, Sciacca L, Vigneri R, Belfiore A. 2002. Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved. J Biol Chem 277:39684-39695 (Pubitemid 35190951)
24. Petersen KF, Shulman GI. 2002. Pathogenesis of skeletal muscle insulin resistance in type 2 diabetes mellitus. Am J Cardiol 90: 11G-18G (Pubitemid 35266676)
25. Pratipanawatr T, Pratipanawatr W, Rosen C, Berria R, Bajaj M, Cusi K, Mandarino L, Kashyap S, Belfort R, DeFronzo RA. 2002. Effect of IGF-I on FFA and glucose metabolism in control and type 2 diabetic subjects. Am J Physiol Endocrinol Metab 282:E1360-E1368 (Pubitemid 34654706)
26. Rajaram S, Baylink DJ, Mohan S. 1997. Insulin-like growth factorbinding proteins in serum and other biological fluids: regulation and functions. Endocr Rev 18:801-831 (Pubitemid 28009568)
27. Rajpathak SN, Gunter MJ, Wylie-Rosett J, Ho GY, Kaplan RC, Muzumdar R, Rohan TE, Strickler HD. 2009. The role of insulin-like growth factor-I and its binding proteins in glucose homeostasis and type 2 diabetes. Diabetes Metab Res Rev 25: 3-12
28. Reaven GM. 1988. Role of insulin resistance in human disease. Diabetes 37:1595-1607 (Pubitemid 19004941)
29. Roberts CT, Jr., Lasky SR, Lowe WL, Jr., Seaman WT, LeRoith D. 1987. Molecular cloning of rat insulin-like growth factor I complementary deoxyribonucleic acids: differential messenger ribonucleic acid processing and regulation by growth hormone in extrahepatic tissues. Mol Endocrinol 1:243-248
30. Russell-Jones DL, Bates AT, Umpleby AM, Hennessy TR, Bowes SB, Hopkins KD, Jackson N, Kelly J, Shojaee-Moradie F, Jones RH, et al. 1995. A comparison of the effects of IGF-I and insulin on glucose metabolism, fat metabolism and the cardiovascular system in normal human volunteers. Eur J Clin Invest 25:403-411
31. Saukkonen T, Amin R, Williams RM, Fox C, Yuen KC, White MA, Umpleby AM, Acerini CL, Dunger DB. 2004. Dose-dependent effects of recombinant human insulin-like growth factor (IGF)-I/ IGF binding proteiN-3 complex on overnight growth hormone secretion and insulin sensitivity in type 1 diabetes. J Clin Endocrinol Metab 89:4634-4641 (Pubitemid 39244481)
32. Sjogren K, Jansson JO, Isaksson OG, Ohlsson C. 2002. A model for tissue-specific inducible insulin-like growth factor-I (IGF-I) inactivation to determine the physiological role of liver-derived IGF-I. Endocrine 19:249-256 (Pubitemid 36250304)
33. Sjogren K, Liu JL, Blad K, Skrtic S, Vidal O, Wallenius V, LeRoith D, Tornell J, Isaksson OG, Jansson JO, Ohlsson C. 1999. Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice. Proc Natl Acad Sci U S A 96: 7088-7092 (Pubitemid 29275014)
34. Taicher GZ, Tinsley FC, Reiderman A, Heiman ML. 2003. Quantitative magnetic resonance (QMR) method for bone and whole-body-composition analysis. Anal Bioanal Chem 377: 990-1002 (Pubitemid 40877830)
35. Tinsley FC, Taicher GZ, Heiman ML. 2004. Evaluation of a quantitative magnetic resonance method for mouse whole body composition analysis. Obes Res 12:150-160 (Pubitemid 41137499)
36. Wagener A, Schmitt AO, Aksu S, Schlote W, Neuschl C, Brockmann GA. 2006. Genetic, sex, and diet effects on body weight and obesity in the Berlin Fat Mouse Inbred lines. Physiol Genomics 27:264-270 (Pubitemid 46708778)
37. Wallenius K, Sjogren K, Peng XD, Park S, Wallenius V, Liu JL, Umaerus M, Wennbo H, Isaksson O, Frohman L, Kineman R, Ohlsson C, Jansson JO. 2001. Liver-derived IGF-I regulates GH secretion at the pituitary level in mice. Endocrinology 142: 4762-4770 (Pubitemid 33022351)
38. Wheatcroft SB, Kearney MT, Shah AM, Ezzat VA, Miell JR, Modo M, Williams SC, Cawthorn WP, Medina-Gomez G, Vidal-Puig A, Sethi JK, Crossey PA. 2007. IGF-binding protein-2 protects against the development of obesity and insulin resistance. Diabetes 56:285-294
39. Woods KA, Camacho-Hubner C, Barter D, Clark AJ, Savage MO. 1997. Insulin-like growth factor I gene deletion causing intrauterine growth retardation and severe short stature. Acta Paediatr Suppl 423:39-45 (Pubitemid 27511886)
40. Woods KA, Camacho-Hubner C, Bergman RN, Barter D, Clark AJ, Savage MO. 2000. Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion. J Clin Endocrinol Metab 85:1407-1411 (Pubitemid 32289481)
41. Xuan S, Kitamura T, Nakae J, Polit K, Kido Y, Fisher PE, Morroni M, Cinti S, White MF, Herrera PL, Accili D, Efstratiadis A. 2002. Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor. J Clin Invest 110: 1011-1019
42. Yakar S, Liu JL, Fernandez AM, Wu Y, Schally AV, Frystyk J, Chernausek SD,MejiaW, Le Roith D. 2001. Liver-specific igf-1 gene deletion leads to muscle insulin insensitivity. Diabetes 50: 1110-1118 (Pubitemid 32374542)
43. Yakar S, Liu JL, Stannard B, Butler A, AcciliD, Sauer B, LeRoithD. 1999. Normal growth and development in the absence of hepatic insulin-like growth factor I. Proc Natl Acad Sci U S A 96: 7324-7329. (Pubitemid 29299660)