Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion

Journal of Clinical Endocrinology and Metabolism

Volumn 85, Issue 4, 2000, Pages 1407-1411

  Woods, K A ^a   Camacho Hubner C ^a   Bergman, R N ^b   Barter, D ^c   Clark, A J L ^a   Savage, M O ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT SOMATOMEDIN C; SOMATOMEDIN C;

ADOLESCENT; ARTICLE; BODY COMPOSITION; BONE DENSITY; CASE REPORT; CHILD GROWTH; DOSE RESPONSE; GENE DELETION; HORMONE DEFICIENCY; HUMAN; INSULIN RESISTANCE; MALE; PRIORITY JOURNAL; SHORT STATURE;

EID: 0034458337     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.85.4.6495     Document Type: Article

References (31)

1. Intrauterine growth retardation and postnatal growth failure associated with deletion of the insulin-like growth factor I gene
2. Clinical features and endocrine status in patients with growth hormone insensitivity (Laron syndrome)
3. Growth hormone (GH) insensitivity due to primary GH receptor deficiency
4. Laron syndrome: Clinical feazes, molecular pathology and treatment
5. A randomized, double blind, placebo controlled trial on safety and efficacy of recombinant human insulin-like growth factor-I in children with growth hormone receptor deficiency
6. Insulin-like growth factor (IGF)-I improves height in growth hormone insensitivity. Two years results
7. Prolonged treatment with recombinant insulin-like growth factor-I in children with growth hormone insensitivity syndrome-a clinical research center study
8. Treatment of growth hormone insensitivity syndrome (GHIS) with insulin-like growth factor (IGF-I)
9. Circulating levels and molecular distribution of the acid-labile subunit of the high molecular weight insulin-like growth factor-binding protein complex
10. Pharmacokinetics of recombinant human insulin-like growth factor I given subcutaneously to healthy volunteers and to patients with growth hormone receptor deficiency
11. Effects of recombinant human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion
12. Metabolic actions of growth hormone: Direct and indirect
13. The methods of auxological anthropometry
14. The modified minimal model: Application to measurement of insulin sensitivity in children
15. New approaches for interpreting projected bone densitometry data
16. Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function
17. The effect of growth hormone on glucose metabolism and insulin secretion in man
18. Insulin resistance in acromegaly: Defects in both hepatic and extrahepatic insulin action
19. Effects of growth hormone on insulin sensitivity and forearm metabolism in normal man
20. Randomised placebo-controlled trial of human recombinant insulin-like growth factor I plus intensive insulin therapy in adolescents with insulin-dependent diabetes mellitus
21. Decreased sex hormone binding globulin (SHBG) and insulin-like growth factor binding protein (IGFBP-1) in extreme obesity
22. Inhibition of sex hormone-binding globulin production in the human hepatoma (Hep G2) cell line by insulin and prolactm
23. Comparative effects of GH, IGF-I and insulin on serum sex hormone binding globulin
24. Laron-type dwarfism (hereditary somatomedin deficiency): A review
25. The effect of long-term growth hormone (GH) treatment on bone mineral density in children with GH deficiency. Role of GH in the attainment of peak bone mass
26. Clinical review 61: Effects of growth hormone on human bone biology
27. Measurement of volumetric bone mineral density accurately determines degree of lumbar undermineralisation in children with growth hormone deficiency
28. Consequences of childhood onset growth hormone deficiency for adult bone mass
29. Bone mineral, histomorphometry, and body composition in adults with growth hormone receptor deficiency
30. Bone mineral density in children and adolescents: Relation to puberty, calcium intake, and physical activity
31. Insulin resistance in short children with intrauterine growth retardation