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Volumn 6, Issue 6, 2011, Pages 823-834

A new look at glutamate and ischemia: NMDA agonist improves long-term functional outcome in a rat model of stroke

Author keywords

cognition; d cycloserine; fMRI; infarction; NMDA receptor; stroke

Indexed keywords

CYCLOSERINE; PHOSPHATE BUFFERED SALINE;

EID: 80155182128     PISSN: 14796708     EISSN: 17486971     Source Type: Journal    
DOI: 10.2217/fnl.11.55     Document Type: Article
Times cited : (60)

References (75)
  • 2
    • 39749191084 scopus 로고    scopus 로고
    • Heart disease and stroke statistics 2008 update a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee
    • Rosamond W, Flegal K, Furie K et al. Heart disease and stroke statistics 2008 update a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 117, E25-E146 (2008).
    • (2008) Circulation , vol.117
    • Rosamond, W.1    Flegal, K.2    Furie, K.3
  • 3
    • 0033820850 scopus 로고    scopus 로고
    • Atherothrombotic middle cerebral artery territory infarction: Topographic diversity with common occurrence of concomitant small cortical and subcortical infarcts
    • Wang KM, Kyoung, KP, Yong SK et al. Atherothrombotic middle cerebral artery territory infarction: topographic diversity with common occurrence of concomitant small cortical and subcortical infarcts. Stroke 31, 2055-2061 (2000).
    • (2000) Stroke , vol.31 , pp. 2055-2061
    • Wang, K.M.1    Kyoung, K.P.2    Yong, S.K.3
  • 5
    • 0026410446 scopus 로고
    • Assessment of neurologic deficits in stroke: Acute-care and rehabilitation implications
    • Phipps L. Assessment of neurologic deficits in stroke: acute-care and rehabilitation implications. Nurs. Clin. North Am. 26, 957-970 (1991).
    • (1991) Nurs. Clin. North Am. , vol.26 , pp. 957-970
    • Phipps, L.1
  • 6
    • 0036158585 scopus 로고    scopus 로고
    • ATLANTIS trial: Results for patients treated within 3 hours of stroke onset. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke (ATLANTIS)
    • Albers GW, Clark WM, Madden KP, Hamilton SA: ATLANTIS trial: results for patients treated within 3 hours of stroke onset. Alteplase Thrombolysis for Acute Noninterventional Therapy in Ischemic Stroke (ATLANTIS). Stroke 33, 493-496 (2002).
    • (2002) Stroke , vol.33 , pp. 493-496
    • Albers, G.W.1    Clark, W.M.2    Madden, K.P.3    Hamilton, S.A.4
  • 7
    • 0037454262 scopus 로고    scopus 로고
    • Tensions Remain over tPA for Stroke
    • DOI 10.1001/jama.289.11.1363
    • Mitka M. Tensions remain over tPA for stroke. JAMA 289, 1363-1364 (2003). (Pubitemid 37430299)
    • (2003) Journal of the American Medical Association , vol.289 , Issue.11 , pp. 1363-1364
    • Mitka, M.1
  • 8
    • 0037313660 scopus 로고    scopus 로고
    • Detriments of tPA for acute stroke in routine clinical practice
    • Novak BL, Force RW. Detriments of tPA for acute stroke in routine clinical practice. J. Fam. Pract. 52(2), 95-96 (2003). (Pubitemid 36188080)
    • (2003) Journal of Family Practice , vol.52 , Issue.2 , pp. 95-96
    • Novak, B.L.1    Force, R.W.2
  • 9
    • 52649165720 scopus 로고    scopus 로고
    • Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke
    • Hacke W, Kaste M, Bluhmki E. Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N. Engl. J. Med. 359, 1317-1329 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , pp. 1317-1329
    • Hacke, W.1    Kaste, M.2    Bluhmki, E.3
  • 10
    • 53249095475 scopus 로고    scopus 로고
    • Thrombolysis with alteplase 3 to 4.5 hours after acute ischaemic stroke (SITS-ISTR): An observational study
    • Wahlgren N, Ahmed N, Davalos A. Thrombolysis with alteplase 3 to 4.5 hours after acute ischaemic stroke (SITS-ISTR): an observational study. Lancet 372, 1303-1309 (2008).
    • (2008) Lancet , vol.372 , pp. 1303-1309
    • Wahlgren, N.1    Ahmed, N.2    Davalos, A.3
  • 11
    • 48849089052 scopus 로고    scopus 로고
    • Neuroprotection for ischemic stroke: Past, present and future
    • Ginsberg MD. Neuroprotection for ischemic stroke: past, present and future. Neuropharmacology 55, 363-389 (2008).
    • (2008) Neuropharmacology , vol.55 , pp. 363-389
    • Ginsberg, M.D.1
  • 12
    • 62949204563 scopus 로고    scopus 로고
    • Current status of neuroprotection for cerebral ischemia: Synoptic overview
    • Ginsberg MD. Current status of neuroprotection for cerebral ischemia: synoptic overview. Stroke 40, S111-S114 (2009).
    • (2009) Stroke , vol.40
    • Ginsberg, M.D.1
  • 13
    • 0021707433 scopus 로고
    • Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
    • DOI 10.1111/j.1471-4159.1984.tb05396.x
    • Benveniste H, Drejer J, Schousboe A, Diemer NH. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43, 1369-1374 (1984). (Pubitemid 15205893)
    • (1984) Journal of Neurochemistry , vol.43 , Issue.5 , pp. 1369-1374
    • Benveniste, H.1    Drejer, J.2    Schousboe, A.3    Diemer, N.H.4
  • 14
    • 0342981455 scopus 로고    scopus 로고
    • Duration of glutamate release after acute ischemic stroke
    • Davalos A, Castillo J, Serena J, Noya M. Duration of glutamate release after acute ischemic stroke. Stroke 28, 708-710 (1997). (Pubitemid 27161450)
    • (1997) Stroke , vol.28 , Issue.4 , pp. 708-710
    • Davalos, A.1    Castillo, J.2    Serena, J.3    Noya, M.4
  • 15
    • 0025265926 scopus 로고
    • The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death
    • Choi DW, Rothman SM. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu. Rev. Neurosci. 13, 171-182 (1990). (Pubitemid 20100647)
    • (1990) Annual Review of Neuroscience , vol.13 , pp. 171-182
    • Choi, D.W.1    Rothman, S.M.2
  • 17
    • 0024316529 scopus 로고
    • Pre- and post-ischemic administration of dizocilpine (MK-801) reduces cerebral necrosis in the rat
    • Rod MR, Auer RN. Pre-and post-ischemic administration of dizocilpine (MK-801) reduces cerebral necrosis in the rat. Can. J. Neurol. Sci. 16, 340-344 (1989). (Pubitemid 19213597)
    • (1989) Canadian Journal of Neurological Sciences , vol.16 , Issue.3 , pp. 340-344
    • Rod, M.R.1    Auer, R.N.2
  • 18
    • 0025763921 scopus 로고
    • Evaluation of a competitive NMDA antagonist (d-CPPene) in feline focal cerebral ischemia
    • Chen M, Bullock R, Graham DI, Frey P, Lowe D, McCulloch J. Evaluation of a competitive NMDA antagonist (d-CPPene) in feline focal cerebral ischemia. Ann. Neurol. 30, 62-70 (1991).
    • (1991) Ann. Neurol. , vol.30 , pp. 62-70
    • Chen, M.1    Bullock, R.2    Graham, D.I.3    Frey, P.4    Lowe, D.5    McCulloch, J.6
  • 19
    • 0030666876 scopus 로고    scopus 로고
    • Cerestat and other NMDA antagonists in ischemic stroke
    • Lees KR. Cerestat and other NMDA antagonists in ischemic stroke. Neurology 49, S66-S69 (1997). (Pubitemid 27495612)
    • (1997) Neurology , vol.49 , Issue.5 SUPPL.
    • Lees, K.R.1
  • 20
    • 0034600485 scopus 로고    scopus 로고
    • Glycine antagonist (gavestinel) in neuroprotection (GAIN International) in patients with acute stroke: A randomised controlled trial
    • Lees KR, Asplund K, Carolei A, Davis SM, Diener HC, Kaste M. Glycine antagonist (gavestinel) in neuroprotection (GAIN International) in patients with acute stroke: a randomized controlled trial. GAIN International Investigators. Lancet 355, 1949-1954 (2000). (Pubitemid 30326099)
    • (2000) Lancet , vol.355 , Issue.9219 , pp. 1949-1954
    • Lees, K.R.1    Asplund, K.2    Carolei, A.3    Davis, S.M.4    Diener, H.-C.5    Kaste, M.6    Orgogozo, J.-M.7    Whitehead, J.8
  • 22
    • 1842483228 scopus 로고    scopus 로고
    • The rise and fall of NMDA antagonists for ischemic stroke
    • DOI 10.2174/1566524043479248
    • Hoyte L, Barber PA, Buchan AM, Hill MD. The rise and fall of NMDA antagonists for ischemic stroke. Curr. Mol. Med. 4(2), 131-136 (2004). (Pubitemid 38425910)
    • (2004) Current Molecular Medicine , vol.4 , Issue.2 , pp. 131-136
    • Hoyte, L.1    Barber, P.A.2    Buchan, A.M.3    Hill, M.D.4
  • 23
    • 0022650213 scopus 로고
    • Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
    • Morris RG, Anderson E, Lynch GS, Baudry M. Selective impairment of learning and blockade of long-term potentiation by an N-methyl-d-aspartate receptor antagonist, AP5. Nature 319, 774-776 (1986). (Pubitemid 16145031)
    • (1986) Nature , vol.319 , Issue.6056 , pp. 774-776
    • Morris, R.G.M.1    Anderson, E.2    Lynch, G.S.3    Baudry, M.4
  • 24
    • 0030762632 scopus 로고    scopus 로고
    • Afferent innervation influences the development of dendritic branches and spines via both activity-dependent and non-activity-dependent mechanisms
    • Kossel AH, Williams CV, Schweizer M, Kater SB. Afferent innervation influences the development of dendritic branches and spines via both activity-dependent and non-activity-dependent mechanisms. J. Neurosci. 17, 6314-6324 (1997). (Pubitemid 27329905)
    • (1997) Journal of Neuroscience , vol.17 , Issue.16 , pp. 6314-6324
    • Kossel, A.H.1    Williams, C.V.2    Schweizer, M.3    Kater, S.B.4
  • 25
    • 36749012387 scopus 로고    scopus 로고
    • The NMDA receptor/ion channel complex: A drug target for modulating synaptic plasticity and excitotoxicity
    • DOI 10.2174/138161207782341321
    • Albensi BC. The NMDA receptor/ion channel complex: a drug target for modulating synaptic plasticity and excitotoxicity. Curr. Pharm. Des. 13(31), 3185-3194 (2007). (Pubitemid 350201695)
    • (2007) Current Pharmaceutical Design , vol.13 , Issue.31 , pp. 3185-3194
    • Albensi, B.C.1
  • 28
    • 77951977455 scopus 로고    scopus 로고
    • Transient focal ischemia results in persistent and widespread neuroinflammation and loss of glutamate NMDA receptors
    • Dhawan J, Benveniste H, Nawrocky M, Smith SD, Biegon A. Transient focal ischemia results in persistent and widespread neuroinflammation and loss of glutamate NMDA receptors. Neuroimage 51, 599-605 (2010).
    • (2010) Neuroimage , vol.51 , pp. 599-605
    • Dhawan, J.1    Benveniste, H.2    Nawrocky, M.3    Smith, S.D.4    Biegon, A.5
  • 29
    • 0032804101 scopus 로고    scopus 로고
    • Distribution of glutamate and proenkephalin messenger RNAs following transient focal cerebral ischemia
    • Friedman LK, Belayev L, Alfonso OF, Ginsberg MD. Distribution of glutamate and proenkephalin messenger RNAs following transient focal cerebral ischemia. Neuroscience 95(3), 841-857 (2000).
    • (2000) Neuroscience , vol.95 , Issue.3 , pp. 841-857
    • Friedman, L.K.1    Belayev, L.2    Alfonso, O.F.3    Ginsberg, M.D.4
  • 30
    • 0026052420 scopus 로고
    • Loss of N-methyl-d-aspartate (NMDA) receptor binding in rat hippocampal areas at the chronic stage after transient forebrain ischemia: Histological and NMDA receptor binding studies
    • Ogawa N, Haba K, Mizukawa K, Asanuma M, Hirata H, Mori A. Loss of N-methyl-d-aspartate (NMDA) receptor binding in rat hippocampal areas at the chronic stage after transient forebrain ischemia: histological and NMDA receptor binding studies. Neurochem. Res. 16(5), 519-524 (1991).
    • (1991) Neurochem. Res. , vol.16 , Issue.5 , pp. 519-524
    • Ogawa, N.1    Haba, K.2    Mizukawa, K.3    Asanuma, M.4    Hirata, H.5    Mori, A.6
  • 31
    • 0025141342 scopus 로고
    • D-cycloserine acts as a partial agonist at the glycine modulatory site of the NMDA receptor expressed in Xenopus oocytes
    • DOI 10.1016/0006-8993(90)90745-W
    • Watson GB, Bolanowski MA, Baganoff MP, Deppeler CL, Lanthorn TH. d-cycloserine acts as a partial agonist at the glycine modulatory site of the NMDA receptor expressed Xenopus oocytes. Brain Res. 510, 158-160 (1990). (Pubitemid 20060820)
    • (1990) Brain Research , vol.510 , Issue.1 , pp. 158-160
    • Watson, G.B.1    Bolanowski, M.A.2    Baganoff, M.P.3    Deppeler, C.L.4    Lanthorn, T.H.5
  • 32
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniotomy in rats. Stroke 20, 84-91 (1989). (Pubitemid 19040218)
    • (1989) Stroke , vol.20 , Issue.1 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 34
    • 58749102792 scopus 로고    scopus 로고
    • The effect of intravenous lidocane on brain activation during non-noxious and acute noxious stimulation of the forepaw: A functional magnetic resonance imaging study in the rat
    • Luo Z, Mei Y, Smith SD et al. The effect of intravenous lidocane on brain activation during non-noxious and acute noxious stimulation of the forepaw: a functional magnetic resonance imaging study in the rat. Anesth. Analg. 108(1), 334-344 (2009).
    • (2009) Anesth. Analg. , vol.108 , Issue.1 , pp. 334-344
    • Luo, Z.1    Mei, Y.2    Smith, S.D.3
  • 35
    • 0023691166 scopus 로고
    • A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data
    • Ennaceur A, Delacour J. A new one-trial test for neurobiological studies of memory in rats. 1: Behavioral data. Behav. Brain Res. 31, 47-59 (1988).
    • (1988) Behav. Brain Res. , vol.31 , pp. 47-59
    • Ennaceur, A.1    Delacour, J.2
  • 36
    • 77649338762 scopus 로고    scopus 로고
    • Intracranial electrode implantation produces regional neuroinflammation and memory deficits in rats
    • Hirshler Y, Polat U, Biegon A. Intracranial electrode implantation produces regional neuroinflammation and memory deficits in rats. Exp. Neurol. 222, 42-45 (2010).
    • (2010) Exp. Neurol. , vol.222 , pp. 42-45
    • Hirshler, Y.1    Polat, U.2    Biegon, A.3
  • 37
    • 0026532184 scopus 로고
    • Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat
    • Memezawa H, Minamisawa H, Smith ML, Siesjo BK. Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat. Exp. Brain Res. 89, 67-78 (1992).
    • (1992) Exp. Brain Res. , vol.89 , pp. 67-78
    • Memezawa, H.1    Minamisawa, H.2    Smith, M.L.3    Siesjo, B.K.4
  • 38
    • 0026598564 scopus 로고
    • Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats
    • Memezawa H, Smith ML, Siesjo BK. Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats. Stroke 23, 552-559 (1992).
    • (1992) Stroke , vol.23 , pp. 552-559
    • Memezawa, H.1    Smith, M.L.2    Siesjo, B.K.3
  • 39
    • 33747180092 scopus 로고    scopus 로고
    • Modification of the method of thread manufacture improves stroke induction rate and reduces mortality after thread-occlusion of the middle cerebral artery in young or aged rats
    • DOI 10.1016/j.jneumeth.2006.01.020, PII S0165027006001014
    • Spratt NJ, Fernandez J, Chen M et al. Modification of the method of thread manufacture improves stroke induction rate and reduces mortality after thread-occlusion of the middle cerebral artery in young or aged rats. J. Neurosci. Methods 155, 285-290 (2006). (Pubitemid 44233014)
    • (2006) Journal of Neuroscience Methods , vol.155 , Issue.2 , pp. 285-290
    • Spratt, N.J.1    Fernandez, J.2    Chen, M.3    Rewell, S.4    Cox, S.5    Van Raay, L.6    Hogan, L.7    Howells, D.W.8
  • 40
    • 0033862478 scopus 로고    scopus 로고
    • Serial MRI after transient focal cerebral ischemia in rats: Dynamics of tissue injury, blood-brain barrier damage, and edema formation
    • Haefelin TN, Kastrup A, de Crespigny A et al. Serial MRI after transient focal cerebral ischemia in rats dynamics of tissue injury, blood-brain barrier damage, and edema formation. Stroke 31, 1965-1973 (2000). (Pubitemid 30620481)
    • (2000) Stroke , vol.31 , Issue.8 , pp. 1965-1973
    • Neumann-Haefelin, T.1    Kastrup, A.2    De Crespigny, A.3    Yenari, M.A.4    Ringer, T.5    Sun, G.H.6    Moseley, M.E.7
  • 41
    • 33646366429 scopus 로고    scopus 로고
    • Present status of magnetic resonance imaging and spectroscopy in animal stroke models
    • Weber R, Ramos-Cabrer P, Hoehn M. Present status of magnetic resonance imaging and spectroscopy in animal stroke models. J. Cereb. Blood Flow Metab. 26, 591-604 (2006).
    • (2006) J. Cereb. Blood Flow Metab. , vol.26 , pp. 591-604
    • Weber, R.1    Ramos-Cabrer, P.2    Hoehn, M.3
  • 42
    • 4644350363 scopus 로고    scopus 로고
    • Functional MRI of the rodent somatosensory pathway using multislice echo planar imaging
    • DOI 10.1002/mrm.20114
    • Keilholz SD, Silva AC, Raman M, Merkle H, Koretsky AP. Functional MRI of the rodent somatosensory pathway using multislice echo planar imaging. Magn. Reson. Med. 52, 89-99 (2004). (Pubitemid 39295260)
    • (2004) Magnetic Resonance in Medicine , vol.52 , Issue.1 , pp. 89-99
    • Keilholz, S.D.1    Silva, A.C.2    Raman, M.3    Merkle, H.4    Koretsky, A.P.5
  • 43
    • 38749089033 scopus 로고    scopus 로고
    • Early prediction of functional recovery after experimental stroke: Functional magnetic resonance imaging, electrophysiology, and behavioral testing in rats
    • DOI 10.1523/JNEUROSCI.4147-07.2008
    • Weber R, Ramos-Cabrer P, Justicia C et al. Early prediction of functional recovery after experimental stroke: functional magnetic resonance imaging, electrophysiology, and behavioral testing in rats. J. Neurosci. 28(5), 1022-1029 (2008). (Pubitemid 351186343)
    • (2008) Journal of Neuroscience , vol.28 , Issue.5 , pp. 1022-1029
    • Weber, R.1    Ramos-Cabrer, P.2    Justicia, C.3    Wiedermann, D.4    Strecker, C.5    Sprenger, C.6    Hoehn, M.7
  • 44
    • 0037439879 scopus 로고    scopus 로고
    • Correlation between brain reorganization, ischemic damage, and neurologic status after transient focal cerebral ischemia in rats: A functional magnetic resonance imaging study
    • Dijkhuizen, RM, Singhal AB, Mandeville JB et al. Correlation between brain reorganization, ischemic damage, and neurologic status after transient focal cerebral ischemia in rats: a functional magnetic resonance imaging study. J. Neurosci. 23(2), 510-517 (2003). (Pubitemid 36139550)
    • (2003) Journal of Neuroscience , vol.23 , Issue.2 , pp. 510-517
    • Dijkhuizen, R.M.1    Singhal, A.B.2    Mandeville, J.B.3    Wu, O.4    Halpern, E.F.5    Finklestein, S.P.6    Rosen, B.R.7    Lo, E.H.8
  • 45
    • 75649145879 scopus 로고    scopus 로고
    • A silver lining to stroke: Does ischemia generate new cortical interneurons?
    • Fishell G, Goldman JE. A silver lining to stroke: does ischemia generate new cortical interneurons? Nat. Neurosci. 13(2), 145-148 (2010).
    • (2010) Nat. Neurosci. , vol.13 , Issue.2 , pp. 145-148
    • Fishell, G.1    Goldman, J.E.2
  • 46
    • 0030602078 scopus 로고    scopus 로고
    • Chronic, post-injury administration of D-cycloserine, an NMDA partial agonist, enhances cognitive performance following experimental brain injury
    • DOI 10.1016/S0006-8993(96)00940-7, PII S0006899396009407
    • Temple MD, Hamm RJ. Chronic, post-injury administration of d-cycloserine, an NMDA partial agonist, enhances cognitive performance following experimental brain injury. Brain Res. 741, 246-251 (1996). (Pubitemid 26426322)
    • (1996) Brain Research , vol.741 , Issue.1-2 , pp. 246-251
    • Temple, M.D.1    Hamm, R.J.2
  • 48
    • 39149095589 scopus 로고    scopus 로고
    • Pattern of time-dependent reduction of histologically determined infarct volume after focal ischaemia in mice
    • Henrich-Noack P, Baldauf K, Reiser G, Reymann KG. Pattern of time-dependent reduction of histologically determined infarct volume after focal ischaemia in mice, Neurosci. Lett. 432, 141-145 (2008).
    • (2008) Neurosci. Lett. , vol.432 , pp. 141-145
    • Henrich-Noack, P.1    Baldauf, K.2    Reiser, G.3    Reymann, K.G.4
  • 49
    • 77957787793 scopus 로고    scopus 로고
    • Brain redundancy: Responsivity or plasticity?
    • Rossini PM. Brain redundancy: responsivity or plasticity? Ann. Neurol. 48, 128-129 (2001).
    • (2001) Ann. Neurol. , vol.48 , pp. 128-129
    • Rossini, P.M.1
  • 51
    • 62049083791 scopus 로고    scopus 로고
    • Acute neuroprotection by pioglitazone after mild brain ischemia without effect on long-term outcome
    • Ji S, Kronenberg G, Balkaya M et al. Acute neuroprotection by pioglitazone after mild brain ischemia without effect on long-term outcome. Exp. Neurol. 216, 321-328 (2009).
    • (2009) Exp. Neurol. , vol.216 , pp. 321-328
    • Ji, S.1    Kronenberg, G.2    Balkaya, M.3
  • 53
    • 0000538225 scopus 로고
    • The restoration of motor function following hemiplegia in man
    • Twitchell TE. The restoration of motor function following hemiplegia in man. Brain 74, 443-480 (1951).
    • (1951) Brain , vol.74 , pp. 443-480
    • Twitchell, T.E.1
  • 54
    • 33744493671 scopus 로고    scopus 로고
    • A critical role for the glial-derived neuromodulator D-serine in the age-related deficits of cellular mechanisms of learning and memory
    • DOI 10.1111/j.1474-9726.2006.00216.x
    • Mothet JP, Rouaud E, Sinet PM et al. A critical role for the glial-derived neuromodulator d-serine in the age-related deficits of cellular mechanisms of learning and memory. Aging Cell 5, 267-274 (2006). (Pubitemid 43805616)
    • (2006) Aging Cell , vol.5 , Issue.3 , pp. 267-274
    • Mothet, J.P.1    Rouaud, E.2    Sinet, P.-M.3    Potier, B.4    Jouvenceau, A.5    Dutar, P.6    Videau, C.7    Epelbaum, J.8    Billard, J.-M.9
  • 56
    • 3242804412 scopus 로고    scopus 로고
    • Consolidation of human motor cortical neuroplasticity by D-cycloserine
    • DOI 10.1038/sj.npp.1300517
    • Nitsche MA, Jaussi W, Liebetanz D, Lang N, Tergau F, Paulus W. Consolidation of human motor cortical neuroplasticity by d-cycloserine. Neuropsychopharmacology 29, 1573-1578 (2004). (Pubitemid 38982250)
    • (2004) Neuropsychopharmacology , vol.29 , Issue.8 , pp. 1573-1578
    • Nitsche, M.A.1    Jaussi, W.2    Liebetanz, D.3    Lang, N.4    Tergau, F.5    Paulus, W.6
  • 57
    • 74149085435 scopus 로고    scopus 로고
    • D-cycloserine improves functional outcome after traumatic brain injury with wide therapeutic window
    • Adeleye A, Shohami E, Nachman D et al. d-cycloserine improves functional outcome after traumatic brain injury with wide therapeutic window. Eur. J. Pharmacol. 629, 25-30 (2010).
    • (2010) Eur. J. Pharmacol. , vol.629 , pp. 25-30
    • Adeleye, A.1    Shohami, E.2    Nachman, D.3
  • 61
    • 0025817573 scopus 로고
    • The effects of dizocilpine (MK-801), phencyclidine, and nimodipine on infarct size 48 h after middle cerebral artery occlusion in the rat
    • Bielenberg GM, Beck T. The effects of dizocilpine (MK-801), phencyclidine, and nimodipine on infarct size 48 h after middle cerebral artery occlusion in the rat. Brain Res. 552, 338-342 (1991).
    • (1991) Brain Res. , vol.552 , pp. 338-342
    • Bielenberg, G.M.1    Beck, T.2
  • 62
    • 0026091467 scopus 로고
    • Reduction of infarct volume by magnesium after middle cerebral artery occlusion in rats
    • Izumi Y, Roussel S, Pinard E, Seylaz J. Reduction of infarct volume by magnesium after middle cerebral artery occlusion in rats. J. Cereb. Blood Flow Metab. 11(6), 1025-1030 (1991).
    • (1991) J. Cereb. Blood Flow Metab. , vol.11 , Issue.6 , pp. 1025-1030
    • Izumi, Y.1    Roussel, S.2    Pinard, E.3    Seylaz, J.4
  • 63
    • 0025763921 scopus 로고
    • Evaluation of a competitive NMDA antagonist (d-CPPene) in feline focal cerebral ischemia
    • Chen M, Bullock R, Graham DI, Frey P, Lowe D, McCulloch J. Evaluation of a competitive NMDA antagonist (d-CPPene) in feline focal cerebral ischemia. Ann. Neurol. 30, 62-70 (1991).
    • (1991) Ann. Neurol. , vol.30 , pp. 62-70
    • Chen, M.1    Bullock, R.2    Graham, D.I.3    Frey, P.4    Lowe, D.5    McCulloch, J.6
  • 65
    • 0027980085 scopus 로고
    • Prolonged effects of MK-801 in the cat during focal cerebral ischemia and recovery: Survival, EEG activity and histopathology
    • DOI 10.1016/0022-510X(94)90164-3
    • Dezsi L, Greenberg JH, Sladky J, Araki N, Hamar J, Reivich M. Prolonged effects of MK-801 in the cat during focal cerebral ischemia and recovery: Survival, EEG activity and histopathology. J. Neurol. Sci. 121(1), 110-120 (1994). (Pubitemid 24025254)
    • (1994) Journal of the Neurological Sciences , vol.121 , Issue.1 , pp. 110-120
    • Dezsi, L.1    Greenberg, J.H.2    Sladky, J.3    Araki, N.4    Hamar, J.5    Reivich, M.6
  • 68
    • 0037375749 scopus 로고    scopus 로고
    • SM-31900, a novel NMDA receptor glycine-binding site antagonist, reduces infarct volume induced by permanent middle cerebral artery occlusion in spontaneously hypertensive rats
    • DOI 10.1016/S0197-0186(02)00137-7, PII S0197018602001377
    • Ohtani K, Tanaka H, Ohno Y. SM-31900, a novel NMDA receptor glycine-binding site antagonist, reduces infarct volume induced by permanent middle cerebral artery occlusion in spontaneously hypertensive rats. Neurochem. Int. 42(5), 375-384 (2003). (Pubitemid 36044670)
    • (2003) Neurochemistry International , vol.42 , Issue.5 , pp. 375-384
    • Ohtani, K.-I.1    Tanaka, H.2    Ohno, Y.3
  • 69
  • 70
    • 0028870990 scopus 로고
    • Safety, tolerability, and pharmacokinetics of the N-methyl-d-aspartate antagonist dextrorphan in patients with acute stroke
    • Albers GW, Atkinson RP, Kelley RE, Rosenbaum DM. Safety, tolerability, and pharmacokinetics of the N-methyl-d-aspartate antagonist dextrorphan in patients with acute stroke. Stroke 26, 254-258 (1995).
    • (1995) Stroke , vol.26 , pp. 254-258
    • Albers, G.W.1    Atkinson, R.P.2    Kelley, R.E.3    Rosenbaum, D.M.4
  • 71
    • 0032875690 scopus 로고    scopus 로고
    • Remacemide hydrochloride: A double-blind, placebo-controlled, safety and tolerability study in patients with acute ischemic stroke
    • Dyker AG, Lees KR. Remacemide hydrochloride: a double-blind, placebo-controlled, safety and tolerability study in patients with acute ischemic stroke. Stroke 30, 1796-1801 (1999). (Pubitemid 29411817)
    • (1999) Stroke , vol.30 , Issue.9 , pp. 1796-1801
    • Dyker, A.G.1    Lees, K.R.2
  • 74
    • 0035134256 scopus 로고    scopus 로고
    • Tolerability of the low-affinity, use-dependent NMDA antagonist AR-R15896AR in stroke patients: A dose-ranging study
    • Lees KR, Dyker AG, Sharma A, Ford GA, Ardron ME, Grosset DG. Tolerability of the low-affinity, use-dependent NMDA antagonist AR-R15896AR in stroke patients: a dose-ranging study. Stroke 32, 466-472 (2001). (Pubitemid 32155236)
    • (2001) Stroke , vol.32 , Issue.2 , pp. 466-472
    • Lees, K.R.1    Dyker, A.G.2    Sharma, A.3    Ford, G.A.4    Ardron, M.E.5    Grosset, D.G.6
  • 75
    • 20244368524 scopus 로고    scopus 로고
    • Gavestinel does not improve outcome after acute intracerebral hemorrhage: An analysis from the GAIN International and GAIN Americas studies
    • DOI 10.1161/01.STR.0000163053.77982.8d
    • Haley EC Jr, Thompson JL, Levin B et al.; GAIN Americas and GAIN International Investigators. Gavestinel does not improve outcome after acute intracerebral hemorrhage: an analysis from the GAIN International and GAIN Americas studies. Stroke 36(5), 1006-1010 (2005). (Pubitemid 40629293)
    • (2005) Stroke , vol.36 , Issue.5 , pp. 1006-1010
    • Haley Jr., E.C.1    Thompson, J.L.P.2    Levin, B.3    Davis, S.4    Lees, K.R.5    Pittman, J.G.6    DeRosa, J.T.7    Ordronneau, P.8    Brown, D.L.9    Sacco, R.L.10


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