Postnatal serotonin type 2 receptor blockade prevents the emergence of anxiety behavior, dysregulated stress-induced immediate early gene responses, and specific transcriptional changes that arise following early life stress

Biological Psychiatry

Volumn 70, Issue 11, 2011, Pages 1024-1032

  Benekareddy, Madhurima ^a   Vadodaria, Krishna C ^a   Nair, Amrita R ^a   Vaidya, Vidita A ^a  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

Activity regulated cytoskeletal associated protein (Arc); habituation; immobilization stress; ketanserin; maternal separation; prefrontal cortex

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; KETANSERIN; MESSENGER RNA; SEROTONIN 2 ANTAGONIST; SEROTONIN 2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY DISORDER; ARTICLE; CONTROLLED STUDY; EARLY LIFE STRESS; FEMALE; GENE EXPRESSION; MATERNAL DEPRIVATION; NONHUMAN; OPEN FIELD TEST; PERINATAL PERIOD; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANXIETY; APOPTOSIS REGULATORY PROTEINS; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FEMALE; FREEZING REACTION, CATALEPTIC; GENE EXPRESSION REGULATION; KETANSERIN; MALE; MATERNAL DEPRIVATION; MAZE LEARNING; MUSCLE PROTEINS; PREFRONTAL CORTEX; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN, 5-HT2; RNA, MESSENGER; SEROTONIN ANTAGONISTS; STRESS, PSYCHOLOGICAL;

EID: 80155172198     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2011.08.005     Document Type: Article

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