Neonatal treatment of rats with the neuroactive steroid tetrahydrodeoxycorticosterone (THDOC) abolishes the behavorial and neuroendocrine consequences of adverse early life events

Journal of Clinical Investigation

Volumn 99, Issue 5, 1997, Pages 962-966

  Patchev, Vladimir K ^a   Montkowski, Alexandra ^a   Rouskova, Daniela ^a   Koranyi, Lajos ^b   Holsboer, Florian ^a   Almeida, Osborne F X ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

Author keywords

corticosterone; corticotropin releasing hormone; glucocorticoid receptor; maternal separation; neurosteroid

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; CORTICOTROPIN RELEASING FACTOR; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; STEROID; TETRAHYDRODEOXYCORTICOSTERONE;

ADRENAL CORTEX; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY NEUROSIS; ARTICLE; BRAIN PROTECTION; CONTROLLED STUDY; DOSE RESPONSE; HISTOCHEMISTRY; HORMONE RELEASE; MATERNAL DEPRIVATION; MAZE TEST; NEWBORN; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; RAT; STRESS; SUBCUTANEOUS DRUG ADMINISTRATION; TRANQUILIZING ACTIVITY; ULTRASOUND; VOCALIZATION;

EID: 0030899031     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119261     Document Type: Article

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