Microarray analysis of human adipose-derived stem cells in three-dimensional collagen culture: Osteogenesis inhibits bone morphogenic protein and wnt signaling pathways, and cyclic tensile strain causes upregulation of proinflammatory cytokine regulators and angiogenic factors

Tissue Engineering - Part A

Volumn 17, Issue 21-22, 2011, Pages 2615-2627

  Charoenpanich, Adisri ^a   Wall, Michelle E ^a   Tucker, Charles J ^b   Andrews, Danica M K ^b   Lalush, David S ^a   Loboa, Elizabeth G ^a,c  

^a Biomedical Research Imaging Center   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c North Carolina State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMATERIALS; BONE; CELL CULTURE; CHEMICAL ANALYSIS; COLLAGEN; ELECTRIC NETWORK ANALYSIS; FRACTURE; GENE EXPRESSION; MECHANISMS; PEPTIDES; SIGNALING; STEM CELLS; THREE DIMENSIONAL; TISSUE; TISSUE ENGINEERING;

3D CULTURE; ADIPOSE DERIVED STEM CELLS; ANGIOGENIC FACTOR; BONE FORMATION; BONE MORPHOGENIC PROTEIN; BONE REGENERATION; BONE TISSUE ENGINEERING; CATENIN SIGNALING; COLLAGEN I; COMBINED EFFECT; CYCLIC TENSILE STRAIN; FIBROBLAST GROWTH FACTOR 2; FRACTURE REPAIR; GENE EXPRESSION PROFILES; INSULIN-LIKE GROWTH FACTOR; INTERLEUKIN-1; MATRIX METALLOPROTEINASE-2; MECHANICAL LOADING; MECHANICAL LOADS; MECHANICAL RESPONSE; MECHANICAL STIMULATION; MECHANICAL STIMULUS; MICROARRAY ANALYSIS; MOLECULAR MECHANISM; OSTEOGENESIS; OSTEOGENIC; OSTEOGENIC DIFFERENTIATION; OSTEOGENIC POTENTIAL; PATHWAY ANALYSIS; PLATELET-DERIVED GROWTH FACTORS; PROINFLAMMATORY CYTOKINES; RECEPTOR ANTAGONISTS; SEPARATE EFFECTS; SUPPRESSOR OF CYTOKINE SIGNALING 3; SYNERGISTIC EFFECT; THREE-DIMENSIONAL (3D); UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR; WNT SIGNALING PATHWAYS;

TENSILE STRAIN;

ANGIOGENIC FACTOR; BONE MORPHOGENETIC PROTEIN; COLLAGEN; CYTOKINE; PLATELET DERIVED GROWTH FACTOR; SOMATOMEDIN C;

ADIPOSE TISSUE; ADULT; ARTICLE; BONE DEVELOPMENT; CELL CULTURE; CYTOLOGY; DNA MICROARRAY; GENETICS; HUMAN; METABOLISM; METHODOLOGY; MIDDLE AGED; PHYSIOLOGY; SIGNAL TRANSDUCTION; STEM CELL; WNT SIGNALING PATHWAY;

ADIPOSE TISSUE; ADULT; ANGIOGENESIS INDUCING AGENTS; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; COLLAGEN; CYTOKINES; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOGENESIS; PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION; STEM CELLS; WNT SIGNALING PATHWAY;

EID: 80155167726     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2011.0107     Document Type: Article

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