메뉴 건너뛰기




Volumn 2, Issue 6, 2011, Pages 448-460

The direct Myc target Pim3 cooperates with other Pim kinases in supporting viability of Myc-induced B-cell lymphomas

Author keywords

c Myc; Cancer; Lymphoma; Oncogenes; Pim 3

Indexed keywords

A 953864; CASPASE; MESSENGER RNA; MYC PROTEIN; PIMI; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN KINASE PIM 1; PROTEIN KINASE PIM2; PROTEIN KINASE PIM3; TUMOR PROTEIN; UNCLASSIFIED DRUG; CASPASE 3; ONCOPROTEIN; PIM3 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; PROTO ONCOGENE PROTEINS PIM; PROTO-ONCOGENE PROTEINS PIM;

EID: 80055113062     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.283     Document Type: Article
Times cited : (46)

References (83)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 2011; 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 0025937489 scopus 로고
    • Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis
    • Askew DS, Ashmun RA, Simmons BC, Cleveland JL. Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis. Oncogene. 1991; 6:1915-1922.
    • (1991) Oncogene , vol.6 , pp. 1915-1922
    • Askew, D.S.1    Ashmun, R.A.2    Simmons, B.C.3    Cleveland, J.L.4
  • 4
    • 1642430733 scopus 로고    scopus 로고
    • Myc pathways provoking cell suicide and cancer
    • Nilsson JA, Cleveland JL. Myc pathways provoking cell suicide and cancer. Oncogene. 2003; 22:9007-9021.
    • (2003) Oncogene , vol.22 , pp. 9007-9021
    • Nilsson, J.A.1    Cleveland, J.L.2
  • 6
    • 0030829781 scopus 로고    scopus 로고
    • Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc
    • Allen JD, Verhoeven E, Domen J, Van Der Valk M, Berns A. Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc. Oncogene. 1997; 15:1133-1141.
    • (1997) Oncogene , vol.15 , pp. 1133-1141
    • Allen, J.D.1    Verhoeven, E.2    Domen, J.3    Van Der Valk, M.4    Berns, A.5
  • 7
    • 0024595556 scopus 로고
    • Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors
    • Van Lohuizen M, Verbeek S, Krimpenfort P, Domen J, Saris C, Radaszkiewicz T, Berns A. Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors. Cell. 1989; 56:673-682.
    • (1989) Cell , vol.56 , pp. 673-682
    • Van Lohuizen, M.1    Verbeek, S.2    Krimpenfort, P.3    Domen, J.4    Saris, C.5    Radaszkiewicz, T.6    Berns, A.7
  • 8
    • 77951092205 scopus 로고    scopus 로고
    • Accelerated hepatocellular carcinoma development in mice expressing the Pim-3 transgene selectively in the liver
    • Wu Y, Wang YY, Nakamoto Y, Li YY, Baba T, Kaneko S, Fujii C, Mukaida N. Accelerated hepatocellular carcinoma development in mice expressing the Pim-3 transgene selectively in the liver. Oncogene. 2010; 29:2228-2237.
    • (2010) Oncogene , vol.29 , pp. 2228-2237
    • Wu, Y.1    Wang, Y.Y.2    Nakamoto, Y.3    Li, Y.Y.4    Baba, T.5    Kaneko, S.6    Fujii, C.7    Mukaida, N.8
  • 9
    • 0036729878 scopus 로고    scopus 로고
    • High-throughput retroviral tagging to identify components of specific signaling pathways in cancer
    • Mikkers H, Allen J, Knipscheer P, Romeijn L, Hart A, Vink E, Berns A. High-throughput retroviral tagging to identify components of specific signaling pathways in cancer. Nat Genet. 2002; 32:153-159.
    • (2002) Nat Genet , vol.32 , pp. 153-159
    • Mikkers, H.1    Allen, J.2    Knipscheer, P.3    Romeijn, L.4    Hart, A.5    Vink, E.6    Berns, A.7
  • 10
    • 0028988929 scopus 로고
    • Proviral tagging in E mumyc transgenic mice lacking the Pim-1 proto-oncogene leads to compensatory activation of Pim-2
    • Van Der Lugt NM, Domen J, Verhoeven E, Linders K, van der Gulden H, Allen J, Berns A. Proviral tagging in E mumyc transgenic mice lacking the Pim-1 proto-oncogene leads to compensatory activation of Pim-2. EMBO J. 1995; 14:2536-2544.
    • (1995) EMBO J , vol.14 , pp. 2536-2544
    • Van Der Lugt, N.M.1    Domen, J.2    Verhoeven, E.3    Linders, K.4    van der Gulden, H.5    Allen, J.6    Berns, A.7
  • 11
    • 0026022673 scopus 로고
    • Mice bearing the E mu-myc and E mupim-1 transgenes develop pre-B-cell leukemia prenatally
    • Verbeek S, Van Lohuizen M, Van der Valk M, Domen J, Kraal G, Berns A. Mice bearing the E mu-myc and E mupim-1 transgenes develop pre-B-cell leukemia prenatally. Mol Cell Biol. 1991; 11:1176-1179.
    • (1991) Mol Cell Biol , vol.11 , pp. 1176-1179
    • Verbeek, S.1    Van Lohuizen, M.2    Van der Valk, M.3    Domen, J.4    Kraal, G.5    Berns, A.6
  • 12
    • 2942700011 scopus 로고    scopus 로고
    • Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors
    • Mikkers H, Nawijn M, Allen J, Brouwers C, Verhoeven E, Jonkers J, Berns A. Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors. Mol Cell Biol. 2004; 24:6104-6115.
    • (2004) Mol Cell Biol , vol.24 , pp. 6104-6115
    • Mikkers, H.1    Nawijn, M.2    Allen, J.3    Brouwers, C.4    Verhoeven, E.5    Jonkers, J.6    Berns, A.7
  • 14
    • 48549096958 scopus 로고    scopus 로고
    • Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels
    • Morishita D, Katayama R, Sekimizu K, Tsuruo T, Fujita N. Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels. Cancer Res. 2008; 68:5076-5085.
    • (2008) Cancer Res , vol.68 , pp. 5076-5085
    • Morishita, D.1    Katayama, R.2    Sekimizu, K.3    Tsuruo, T.4    Fujita, N.5
  • 16
    • 29244464759 scopus 로고    scopus 로고
    • The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C
    • Bachmann M, Kosan C, Xing PX, Montenarh M, Hoffmann I, Moroy T. The oncogenic serine/threonine kinase Pim-1 directly phosphorylates and activates the G2/M specific phosphatase Cdc25C. Int J Biochem Cell Biol. 2006; 38:430-443.
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 430-443
    • Bachmann, M.1    Kosan, C.2    Xing, P.X.3    Montenarh, M.4    Hoffmann, I.5    Moroy, T.6
  • 19
    • 2342629177 scopus 로고    scopus 로고
    • Pim-1 kinase inhibits STAT5-dependent transcription via its interactions with SOCS1 and SOCS3
    • Peltola KJ, Paukku K, Aho TL, Ruuska M, Silvennoinen O, Koskinen PJ. Pim-1 kinase inhibits STAT5-dependent transcription via its interactions with SOCS1 and SOCS3. Blood. 2004; 103:3744-3750.
    • (2004) Blood , vol.103 , pp. 3744-3750
    • Peltola, K.J.1    Paukku, K.2    Aho, T.L.3    Ruuska, M.4    Silvennoinen, O.5    Koskinen, P.J.6
  • 22
    • 3343007095 scopus 로고    scopus 로고
    • Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site
    • Aho TL, Sandholm J, Peltola KJ, Mankonen HP, Lilly M, Koskinen PJ. Pim-1 kinase promotes inactivation of the pro-apoptotic Bad protein by phosphorylating it on the Ser112 gatekeeper site. FEBS Lett. 2004; 571:43-49.
    • (2004) FEBS Lett , vol.571 , pp. 43-49
    • Aho, T.L.1    Sandholm, J.2    Peltola, K.J.3    Mankonen, H.P.4    Lilly, M.5    Koskinen, P.J.6
  • 23
    • 32944458740 scopus 로고    scopus 로고
    • Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL
    • Macdonald A, Campbell DG, Toth R, McLauchlan H, Hastie CJ, Arthur JS. Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL. BMC Cell Biol. 2006; 7:1.
    • (2006) BMC Cell Biol , vol.7 , pp. 1
    • Macdonald, A.1    Campbell, D.G.2    Toth, R.3    McLauchlan, H.4    Hastie, C.J.5    Arthur, J.S.6
  • 24
    • 0242580961 scopus 로고    scopus 로고
    • The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death
    • Yan B, Zemskova M, Holder S, Chin V, Kraft A, Koskinen PJ, Lilly M. The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death. J Biol Chem. 2003; 278:45358-45367.
    • (2003) J Biol Chem , vol.278 , pp. 45358-45367
    • Yan, B.1    Zemskova, M.2    Holder, S.3    Chin, V.4    Kraft, A.5    Koskinen, P.J.6    Lilly, M.7
  • 25
    • 49649127162 scopus 로고    scopus 로고
    • Pim kinasedependent inhibition of c-Myc degradation
    • Zhang Y, Wang Z, Li X, Magnuson NS. Pim kinasedependent inhibition of c-Myc degradation. Oncogene. 2008; 27:4809-4819.
    • (2008) Oncogene , vol.27 , pp. 4809-4819
    • Zhang, Y.1    Wang, Z.2    Li, X.3    Magnuson, N.S.4
  • 26
    • 0041292007 scopus 로고    scopus 로고
    • Pim-1 phosphorylates the DNA binding domain of c-Myb
    • Winn LM, Lei W, Ness SA. Pim-1 phosphorylates the DNA binding domain of c-Myb. Cell Cycle. 2003; 2:258-262.
    • (2003) Cell Cycle , vol.2 , pp. 258-262
    • Winn, L.M.1    Lei, W.2    Ness, S.A.3
  • 27
    • 33744774483 scopus 로고    scopus 로고
    • Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity
    • Aho TL, Sandholm J, Peltola KJ, Ito Y, Koskinen PJ. Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity. BMC Cell Biol. 2006; 7:21.
    • (2006) BMC Cell Biol , vol.7 , pp. 21
    • Aho, T.L.1    Sandholm, J.2    Peltola, K.J.3    Ito, Y.4    Koskinen, P.J.5
  • 28
    • 34547599505 scopus 로고    scopus 로고
    • PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation
    • Zippo A, De Robertis A, Serafini R, Oliviero S. PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation. Nat Cell Biol. 2007; 9:932-944.
    • (2007) Nat Cell Biol , vol.9 , pp. 932-944
    • Zippo, A.1    De Robertis, A.2    Serafini, R.3    Oliviero, S.4
  • 30
    • 79960628093 scopus 로고    scopus 로고
    • Myc on my mind: a transcription factor family's essential role in brain development
    • Mainwaring LA, Bhatia B, Kenney AM. Myc on my mind: a transcription factor family's essential role in brain development. Oncotarget. 2010; 1:86-88.
    • (2010) Oncotarget , vol.1 , pp. 86-88
    • Mainwaring, L.A.1    Bhatia, B.2    Kenney, A.M.3
  • 31
    • 0026519022 scopus 로고
    • Determination of the DNA sequence recognized by the bHLH-zip domain of the N-Myc protein
    • Alex R, Sozeri O, Meyer S, Dildrop R. Determination of the DNA sequence recognized by the bHLH-zip domain of the N-Myc protein. Nucleic Acids Res. 1992; 20:2257-2263.
    • (1992) Nucleic Acids Res , vol.20 , pp. 2257-2263
    • Alex, R.1    Sozeri, O.2    Meyer, S.3    Dildrop, R.4
  • 32
    • 0026563516 scopus 로고
    • max encodes a sequence-specific DNA-binding protein and is not regulated by serum growth factors
    • Berberich S, Hyde-DeRuyscher N, Espenshade P, Cole M. max encodes a sequence-specific DNA-binding protein and is not regulated by serum growth factors. Oncogene. 1992; 7:775-779.
    • (1992) Oncogene , vol.7 , pp. 775-779
    • Berberich, S.1    Hyde-DeRuyscher, N.2    Espenshade, P.3    Cole, M.4
  • 37
    • 0026737229 scopus 로고
    • DNA binding activities of c-Myc purified from eukaryotic cells
    • Papoulas O, Williams NG, Kingston RE. DNA binding activities of c-Myc purified from eukaryotic cells. J Biol Chem. 1992; 267:10470-10480.
    • (1992) J Biol Chem , vol.267 , pp. 10470-10480
    • Papoulas, O.1    Williams, N.G.2    Kingston, R.E.3
  • 38
    • 66149120222 scopus 로고    scopus 로고
    • Myc sensitizes p53-deficient cancer cells to the DNAdamaging effects of the DNA methyltransferase inhibitor decitabine
    • Höglund A, Nilsson LM, Forshell LP, Maclean KH, Nilsson JA. Myc sensitizes p53-deficient cancer cells to the DNAdamaging effects of the DNA methyltransferase inhibitor decitabine. Blood. 2009; 113:4281-4288.
    • (2009) Blood , vol.113 , pp. 4281-4288
    • Höglund, A.1    Nilsson, L.M.2    Forshell, L.P.3    Maclean, K.H.4    Nilsson, J.A.5
  • 39
    • 77949715975 scopus 로고    scopus 로고
    • Chemoprevention of B-cell lymphomas by inhibition of the Myc target spermidine synthase
    • Forshell TP, Rimpi S, Nilsson JA. Chemoprevention of B-cell lymphomas by inhibition of the Myc target spermidine synthase. Cancer Prev Res (Phila Pa). 2010; 3:140-147.
    • (2010) Cancer Prev Res (Phila Pa) , vol.3 , pp. 140-147
    • Forshell, T.P.1    Rimpi, S.2    Nilsson, J.A.3
  • 42
    • 0035881691 scopus 로고    scopus 로고
    • Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter
    • Bouchard C, Dittrich O, Kiermaier A, Dohmann K, Menkel A, Eilers M, Luscher B. Regulation of cyclin D2 gene expression by the Myc/Max/Mad network: Myc-dependent TRRAP recruitment and histone acetylation at the cyclin D2 promoter. Genes Dev. 2001; 15:2042-2047.
    • (2001) Genes Dev , vol.15 , pp. 2042-2047
    • Bouchard, C.1    Dittrich, O.2    Kiermaier, A.3    Dohmann, K.4    Menkel, A.5    Eilers, M.6    Luscher, B.7
  • 45
    • 0034051902 scopus 로고    scopus 로고
    • Genomic-scale gene expression profiling of normal and malignant immune cells
    • Alizadeh AA, Staudt LM. Genomic-scale gene expression profiling of normal and malignant immune cells. Curr Opin Immunol. 2000; 12:219-225.
    • (2000) Curr Opin Immunol , vol.12 , pp. 219-225
    • Alizadeh, A.A.1    Staudt, L.M.2
  • 47
  • 51
    • 0037286854 scopus 로고    scopus 로고
    • Cell cycle alterations in the blastoid variant of mantle cell lymphoma (MCL-BV) as detected by gene expression profiling of mantle cell lymphoma (MCL) and MCL-BV
    • de Vos S, Krug U, Hofmann WK, Pinkus GS, Swerdlow SH, Wachsman W, Grogan TM, Said JW, Koeffler HP. Cell cycle alterations in the blastoid variant of mantle cell lymphoma (MCL-BV) as detected by gene expression profiling of mantle cell lymphoma (MCL) and MCL-BV. Diagn Mol Pathol. 2003; 12:35-43.
    • (2003) Diagn Mol Pathol , vol.12 , pp. 35-43
    • de Vos, S.1    Krug, U.2    Hofmann, W.K.3    Pinkus, G.S.4    Swerdlow, S.H.5    Wachsman, W.6    Grogan, T.M.7    Said, J.W.8    Koeffler, H.P.9
  • 52
    • 57049101684 scopus 로고    scopus 로고
    • PIM1 expression predict outcome in mantle cell lymphoma treated with high dose therapy, stem cell transplantation and rituximab: a Cancer and Leukemia Group B 59909 correlative science study
    • Hsi ED, Jung SH, Lai R, Johnson JL, Cook JR, Jones D, Devos S, Cheson BD, Damon LE, Said J. Ki67 and PIM1 expression predict outcome in mantle cell lymphoma treated with high dose therapy, stem cell transplantation and rituximab: a Cancer and Leukemia Group B 59909 correlative science study. Leuk Lymphoma. 2008; 49:2081-2090.
    • (2008) Leuk Lymphoma , vol.49 , pp. 2081-2090
    • Hsi, E.D.1    Jung, S.H.2    Lai, R.3    Johnson, J.L.4    Cook, J.R.5    Jones, D.6    Devos, S.7    Cheson, B.D.8    Damon, L.E.9    Said, J.10    Ki67, .11
  • 57
    • 0043192901 scopus 로고    scopus 로고
    • A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma
    • Wright G, Tan B, Rosenwald A, Hurt EH, Wiestner A, Staudt LM. A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma. Proc Natl Acad Sci U S A. 2003; 100:9991-9996.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9991-9996
    • Wright, G.1    Tan, B.2    Rosenwald, A.3    Hurt, E.H.4    Wiestner, A.5    Staudt, L.M.6
  • 62
    • 51049109691 scopus 로고    scopus 로고
    • The PIM1 kinase is a critical component of a survival pathway activated by docetaxel and promotes survival of docetaxeltreated prostate cancer cells
    • Zemskova M, Sahakian E, Bashkirova S, Lilly M. The PIM1 kinase is a critical component of a survival pathway activated by docetaxel and promotes survival of docetaxeltreated prostate cancer cells. J Biol Chem. 2008; 283:20635-20644.
    • (2008) J Biol Chem , vol.283 , pp. 20635-20644
    • Zemskova, M.1    Sahakian, E.2    Bashkirova, S.3    Lilly, M.4
  • 65
    • 0028930840 scopus 로고
    • An E-boxmediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants
    • Miltenberger RJ, Sukow KA, Farnham PJ. An E-boxmediated increase in cad transcription at the G1/S-phase boundary is suppressed by inhibitory c-Myc mutants. Mol Cell Biol. 1995; 15:2527-2535.
    • (1995) Mol Cell Biol , vol.15 , pp. 2527-2535
    • Miltenberger, R.J.1    Sukow, K.A.2    Farnham, P.J.3
  • 66
    • 0036316013 scopus 로고    scopus 로고
    • A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the onecarbon unit for cell metabolism
    • Nikiforov MA, Chandriani S, O'Connell B, Petrenko O, Kotenko I, Beavis A, Sedivy JM, Cole MD. A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the onecarbon unit for cell metabolism. Mol Cell Biol. 2002; 22:5793-5800.
    • (2002) Mol Cell Biol , vol.22 , pp. 5793-5800
    • Nikiforov, M.A.1    Chandriani, S.2    O'Connell, B.3    Petrenko, O.4    Kotenko, I.5    Beavis, A.6    Sedivy, J.M.7    Cole, M.D.8
  • 69
    • 0033083261 scopus 로고    scopus 로고
    • IL-4 selectively inhibits IL-2-triggered Stat5 activation, but not proliferation, in human T cells
    • Castro A, Sengupta TK, Ruiz DC, Yang E, Ivashkiv LB. IL-4 selectively inhibits IL-2-triggered Stat5 activation, but not proliferation, in human T cells. J Immunol. 1999; 162:1261-1269.
    • (1999) J Immunol , vol.162 , pp. 1261-1269
    • Castro, A.1    Sengupta, T.K.2    Ruiz, D.C.3    Yang, E.4    Ivashkiv, L.B.5
  • 70
    • 0035947608 scopus 로고    scopus 로고
    • Novel NEMO/IkappaB kinase and NF-kappa B target genes at the pre-B to immature B cell transition
    • Li J, Peet GW, Balzarano D, Li X, Massa P, Barton RW, Marcu KB. Novel NEMO/IkappaB kinase and NF-kappa B target genes at the pre-B to immature B cell transition. J Biol Chem. 2001; 276:18579-18590.
    • (2001) J Biol Chem , vol.276 , pp. 18579-18590
    • Li, J.1    Peet, G.W.2    Balzarano, D.3    Li, X.4    Massa, P.5    Barton, R.W.6    Marcu, K.B.7
  • 71
    • 0033560095 scopus 로고    scopus 로고
    • Interferon-alpha activates multiple STAT proteins and upregulates proliferation-associated IL-2Ralpha, c-myc, and pim-1 genes in human T cells
    • Matikainen S, Sareneva T, Ronni T, Lehtonen A, Koskinen PJ, Julkunen I. Interferon-alpha activates multiple STAT proteins and upregulates proliferation-associated IL-2Ralpha, c-myc, and pim-1 genes in human T cells. Blood. 1999; 93:1980-1991.
    • (1999) Blood , vol.93 , pp. 1980-1991
    • Matikainen, S.1    Sareneva, T.2    Ronni, T.3    Lehtonen, A.4    Koskinen, P.J.5    Julkunen, I.6
  • 72
    • 0028109330 scopus 로고
    • Induction of tyrosine phosphorylation of Vav and expression of Pim-1 correlates with Jak2-mediated growth signaling from the erythropoietin receptor
    • Miura O, Miura Y, Nakamura N, Quelle FW, Witthuhn BA, Ihle JN, Aoki N. Induction of tyrosine phosphorylation of Vav and expression of Pim-1 correlates with Jak2-mediated growth signaling from the erythropoietin receptor. Blood. 1994; 84:4135-4141.
    • (1994) Blood , vol.84 , pp. 4135-4141
    • Miura, O.1    Miura, Y.2    Nakamura, N.3    Quelle, F.W.4    Witthuhn, B.A.5    Ihle, J.N.6    Aoki, N.7
  • 73
    • 0033451992 scopus 로고    scopus 로고
    • Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis
    • Shirogane T, Fukada T, Muller JM, Shima DT, Hibi M, Hirano T. Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis. Immunity. 1999; 11:709-719.
    • (1999) Immunity , vol.11 , pp. 709-719
    • Shirogane, T.1    Fukada, T.2    Muller, J.M.3    Shima, D.T.4    Hibi, M.5    Hirano, T.6
  • 74
    • 55449105991 scopus 로고    scopus 로고
    • Maximal STAT5-induced proliferation and self-renewal at intermediate STAT5 activity levels
    • Wierenga AT, Vellenga E, Schuringa JJ. Maximal STAT5-induced proliferation and self-renewal at intermediate STAT5 activity levels. Mol Cell Biol. 2008; 28:6668-6680.
    • (2008) Mol Cell Biol , vol.28 , pp. 6668-6680
    • Wierenga, A.T.1    Vellenga, E.2    Schuringa, J.J.3
  • 75
    • 0037080197 scopus 로고    scopus 로고
    • CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway
    • Zhu N, Ramirez LM, Lee RL, Magnuson NS, Bishop GA, Gold MR. CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway. J Immunol. 2002; 168:744-754.
    • (2002) J Immunol , vol.168 , pp. 744-754
    • Zhu, N.1    Ramirez, L.M.2    Lee, R.L.3    Magnuson, N.S.4    Bishop, G.A.5    Gold, M.R.6
  • 76
    • 0037569709 scopus 로고    scopus 로고
    • PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins
    • Deneen B, Welford SM, Ho T, Hernandez F, Kurland I, Denny CT. PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins. Mol Cell Biol. 2003; 23:3897-3908.
    • (2003) Mol Cell Biol , vol.23 , pp. 3897-3908
    • Deneen, B.1    Welford, S.M.2    Ho, T.3    Hernandez, F.4    Kurland, I.5    Denny, C.T.6
  • 77
    • 62849113353 scopus 로고    scopus 로고
    • Essential contribution of Ets-1 to constitutive Pim-3 expression in human pancreatic cancer cells
    • Li YY, Wu Y, Tsuneyama K, Baba T, Mukaida N. Essential contribution of Ets-1 to constitutive Pim-3 expression in human pancreatic cancer cells. Cancer Sci. 2009; 100:396-404.
    • (2009) Cancer Sci , vol.100 , pp. 396-404
    • Li, Y.Y.1    Wu, Y.2    Tsuneyama, K.3    Baba, T.4    Mukaida, N.5
  • 80
    • 79957977839 scopus 로고    scopus 로고
    • The pursuit of oncotargets through understanding defective cell regulation
    • Qiao M, Shi Q, Pardee AB. The pursuit of oncotargets through understanding defective cell regulation. Oncotarget. 2010; 1:544-551.
    • (2010) Oncotarget , vol.1 , pp. 544-551
    • Qiao, M.1    Shi, Q.2    Pardee, A.B.3
  • 81
    • 22544444514 scopus 로고    scopus 로고
    • Caspase-independent cell death
    • Kroemer G, Martin SJ. Caspase-independent cell death. Nat Med. 2005; 11:725-730.
    • (2005) Nat Med , vol.11 , pp. 725-730
    • Kroemer, G.1    Martin, S.J.2
  • 82
    • 34247136256 scopus 로고    scopus 로고
    • Metabolic enzymes regulated by the Myc oncogene are possible targets for chemotherapy or chemoprevention
    • Rimpi S, Nilsson JA. Metabolic enzymes regulated by the Myc oncogene are possible targets for chemotherapy or chemoprevention. Biochem Soc Trans. 2007; 35:305-310.
    • (2007) Biochem Soc Trans , vol.35 , pp. 305-310
    • Rimpi, S.1    Nilsson, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.