Aging neural progenitor cells have decreased mitochondrial content and lower oxidative metabolism

Journal of Biological Chemistry

Volumn 286, Issue 44, 2011, Pages 38592-38601

  Stoll, Elizabeth A ^a   Cheung, Willy ^b   Mikheev, Andrei M ^c   Sweet, Ian R ^a,c   Bielas, Jason H ^a   Zhang, Jing ^a   Rostomily, Robert C ^c   Horner, Philip J ^a,c  

^a UNIVERSITY OF WASHINGTON   (United States)

^b University of Washington   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULAR METABOLISM; MAMMALIAN BRAIN; METABOLIC PHENOTYPE; MITOCHONDRIAL DNA; MITOCHONDRIAL INHIBITORS; MOLECULAR CHANGES; MUTATION RATES; NEURAL PROGENITOR CELLS; NEUROGENESIS; OXIDATIVE METABOLISM; OXYGEN CONSUMPTION RATE; PROTEIN EXPRESSIONS; SUBCELLULAR STRUCTURE;

MAMMALS; METABOLISM; OXYGEN; PHYSIOLOGY;

MITOCHONDRIA;

CELL PROTEIN; MITOCHONDRIAL DNA; ROTENONE;

ADULT ANIMAL; AEROBIC METABOLISM; AGE; ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CELL AGING; CELL FUNCTION; CELL METABOLISM; CELL PROLIFERATION; CELL REGENERATION; CELL STRUCTURE; CONTROLLED STUDY; FOREBRAIN; GENE MUTATION; MITOCHONDRION; MOUSE; NEURAL STEM CELL; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEOMICS;

AGING; ANIMALS; ANOXIA; CELL PROLIFERATION; FEMALE; MICE; MICE, INBRED C57BL; MICROSCOPY, CONFOCAL; MITOCHONDRIA; MODELS, BIOLOGICAL; NEUROGENESIS; NEURONS; OXYGEN; OXYGEN CONSUMPTION; PROTEOMICS; REGENERATION; STEM CELLS;

MAMMALIA;

EID: 80055092772     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.252171     Document Type: Article

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