To intercalate or semiintercalate, or both?

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 43, 2011, Pages 17573-17574

  Turro, Claudia ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BASE; DOUBLE STRANDED DNA; RUTHENIUM COMPLEX;

ANTINEOPLASTIC ACTIVITY; CRYSTAL STRUCTURE; DNA STRUCTURE; DRUG DNA BINDING; DRUG DNA INTERACTION; DRUG STRUCTURE; INTERCALATION COMPLEX; NOTE; PRIORITY JOURNAL;

AZA COMPOUNDS; DNA; INTERCALATING AGENTS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; ORGANOMETALLIC COMPOUNDS; PHENANTHRENES;

EID: 80055083441     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1114519108     Document Type: Note

References (15)

1. Antonarakis ES, Emadi A (2010) Ruthenium-based chemotherapeutics: Are they ready for prime time? Cancer Chemother Pharmacol 66:1-9.
2. Genereux JC, Boal AK, Barton JK (2010) DNA-mediated charge transport in redox sensing and signaling. J Am Chem Soc 132:891-905.
3. Zhao R, et al. (2009) Nuclear targets of photodynamic tridentate ruthenium complexes. Dalton Trans 48: 10926-10931.
4. Hall PH, et al. (2011) Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand. Proc Natl Acad Sci USA 108: 17610-17614.
5. Zeglis BM, Pierre VC, Barton JK (2007) Metallo-intercalators and metallo-insertors. Chem Commun (Camb) (44):4565-4579. (Pubitemid 350077044)
6. Ohndorf UM, Rould MA, He Q, Pabo CO, Lippard SJ (1999) Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins. Nature 399:708-712. (Pubitemid 29289069)
7. Todd RC, Lippard SJ (2009) Inhibition of transcription by platinum antitumor compounds. Metallomics 1: 280-291.
8. Jung Y, Lippard SJ (2007) Direct cellular responses to platinum-induced DNA damage. Chem Rev 107: 1387-1407. (Pubitemid 46864967)
9. Fu PKL, Bradley PM, Turro C (2003) Stabilization of duplex DNA structure and suppression of transcription in vitro by bis(quinone diimine) complexes of rhodium(III) and ruthenium(II). Inorg Chem 42:878-884.
10. Aguirre JD, Lutterman DA, Angeles-Boza AM, Dunbar KR, Turro C (2007) Effect of axial coordination on the electronic structure and biological activity of dirhodium(II,II) complexes. Inorg Chem 46:7494-7502.
11. Aguirre JD, et al. (2009) Anticancer activity of hetero-leptic diimine complexes of dirhodium: A study of intercalating properties, hydrophobicity and in cellulo activity. Dalton Trans 48:10806-10812.
12. Merino EJ, Boal AK, Barton JK (2008) Biological contexts for DNA charge transport chemistry. Curr Opin Chem Biol 12:229-237.
13. Barton JK, Olmon ED, Sontz PA (2011) Metal complexes for DNA-mediated charge transport. Coord Chem Rev 255:619-634.
14. Elias B, Kirsch-De Mesmaeker A (2006) Photo-reduction of polyazaaromatic Ru(II) complexes by biomolecules and possible applications. Coord Chem Rev 250: 1627-1641.
15. Noll DM, Mason TM, Miller PS (2006) Formation and repair of interstrand cross-links in DNA. Chem Rev 106: 277-301.