Direct aminoalkylation of arenes, heteroarenes, and alkenes via Ni-catalyzed Negishi cross-coupling reactions

Journal of Organic Chemistry

Volumn 76, Issue 21, 2011, Pages 8891-8906

  Melzig, Laurin ^a   Dennenwaldt, Teresa ^a   Gavryushin, Andrey ^a   Knochel, Paul ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENYL; AMINE MOIETIES; BIOLOGICALLY ACTIVE MOLECULES; CROSS-COUPLINGS; ELECTROPHILES; FUNCTIONALIZED; GRIGNARD REAGENT; HETEROARENES; NATURAL PRODUCTS; NEGISHI CROSS-COUPLING; ROOM TEMPERATURE; TOTAL SYNTHESIS; TRIFLATES;

BROMINE COMPOUNDS; CHLORINE COMPOUNDS; OLEFINS; SYNTHESIS (CHEMICAL);

CATALYSIS;

2 (1 METHYL 1,2,3,4 TETRAHYDROQUINOLIN 2 YL)ETHANOL; 2 (1 METHYL 1,2,3,4 TETRAHYDROQUINOLIN 2 YL)ETHYL)MAGNESIUM CHLORIDE; 2 (1,2,3,4 TETRAHYDROQUINOLIN 2 YL)ETHANOL; 2 (2 (BENZO[D][1,3]DIOXOL 5 YL)ETHYL) 1 METHYL 1,2,3,4 TETRAHYDROQUINOLINE; 2 (2 CLOROETHYL) 1 METHYL 1,2,3,4 TETRAHYDROQUINOLINE; 2 (3,4 DIMETHOXYPHENETHYL) 1 METHYL 1,2,3,4 TETRAHYDROQUINOLINE; 2 (QUINOLIN 2 YL)ETHANOL; 3 (ISOQUINOLIN 4 YL) N,N DIMETHYLPROPAN 1 AMINE; ALKENE; AMINE; ANTIINFECTIVE AGENT; BROMIDE; CHLORIDE; CUSPARINE; ELECTROPHILE; GALIPININE; N,N DIMETHYL 3 (QUINOXALIN 6 YL)PROPAN 1 AMINE; NICKEL; PIPERIDINE; POLYCYCLIC AROMATIC HYDROCARBON; REAGENT; TROPANE ALKALOID; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CATALYSIS; CROSS COUPLING REACTION; DRUG SYNTHESIS; GRIGNARD REACTION; ROOM TEMPERATURE;

ALKALOIDS; ALKENES; ALKYLATION; CATALYSIS; CROSS-LINKING REAGENTS; HETEROCYCLIC COMPOUNDS; HYDROCARBONS, HALOGENATED; INDICATORS AND REAGENTS; MOLECULAR STRUCTURE; NICKEL; QUINOLINES; STEREOISOMERISM;

EID: 80055076772     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo201630e     Document Type: Article

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