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Volumn 6, Issue 10, 2011, Pages

Evidence of mext-independent overexpression of mexef-oprn multidrug efflux pump of pseudomonas aeruginosa in presence of metabolic stress

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CHLORAMPHENICOL; CIPROFLOXACIN; MEXEF OPRN PROTEIN; MEXT PROTEIN; OPRN PROTEIN; TRIMETHOPRIM; UNCLASSIFIED DRUG;

EID: 80055040233     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026520     Document Type: Article
Times cited : (22)

References (46)
  • 1
    • 0037579301 scopus 로고
    • Pseudomonas pneumonia and bacteremia in the immunocompromised patient
    • In: Fick RBJ, editors, Boca Raton, Ann Arbor, London, Tokyo, CRC Press
    • Aksamit TR, (1993) Pseudomonas pneumonia and bacteremia in the immunocompromised patient. In: Fick RBJ, editors. Pseudomonas aeruginosa: The opportunist- pathogenesis and disease Boca Raton, Ann Arbor, London, Tokyo CRC Press pp. 177-188.
    • (1993) Pseudomonas Aeruginosa: The Opportunist - Pathogenesis and Disease , pp. 177-188
    • Aksamit, T.R.1
  • 3
  • 5
    • 0032460811 scopus 로고    scopus 로고
    • Pacemaker-related endocarditis. Report of 7 cases and review of the literature
    • Laguno M, Miro O, Font C, de la Sierra A, (1998) Pacemaker-related endocarditis. Report of 7 cases and review of the literature. Cardiology 90: 244-248.
    • (1998) Cardiology , vol.90 , pp. 244-248
    • Laguno, M.1    Miro, O.2    Font, C.3    De la Sierra, A.4
  • 8
    • 0032860807 scopus 로고    scopus 로고
    • Emergence of multidrug-resistant mutants is increased under antibiotic selective pressure in Pseudomonas aeruginosa
    • Alonso A, Campanario E, Martinez JL, (1999) Emergence of multidrug-resistant mutants is increased under antibiotic selective pressure in Pseudomonas aeruginosa. Microbiology 145: 2857-2862.
    • (1999) Microbiology , vol.145 , pp. 2857-2862
    • Alonso, A.1    Campanario, E.2    Martinez, J.L.3
  • 9
    • 0035339126 scopus 로고    scopus 로고
    • Contribution of multidrug efflux pumps to multiple antibiotic resistance in veterinary clinical isolates of Pseudomonas aeruginosa
    • Beinlich KL, Chuanchuen R, Schweizer HP, (2001) Contribution of multidrug efflux pumps to multiple antibiotic resistance in veterinary clinical isolates of Pseudomonas aeruginosa. FEMS Microbiol Lett 198: 129-134.
    • (2001) FEMS Microbiol Lett , vol.198 , pp. 129-134
    • Beinlich, K.L.1    Chuanchuen, R.2    Schweizer, H.P.3
  • 10
    • 0028789107 scopus 로고
    • Mechanisms of resistance to beta-lactam antibiotics amongst Pseudomonas aeruginosa isolates collected in the UK in 1993
    • Chen HY, Yuan M, Livermore DM, (1995) Mechanisms of resistance to beta-lactam antibiotics amongst Pseudomonas aeruginosa isolates collected in the UK in 1993. J Med Microbiol 43: 300-309.
    • (1995) J Med Microbiol , vol.43 , pp. 300-309
    • Chen, H.Y.1    Yuan, M.2    Livermore, D.M.3
  • 11
    • 0029836682 scopus 로고    scopus 로고
    • Multidrug efflux in intrinsic resistance to trimethoprim and sulfamethoxazole in Pseudomonas aeruginosa
    • Köhler T, Kok M, Michea-Hamzehpour M, Plesiat P, Gotoh N, et al. (1996) Multidrug efflux in intrinsic resistance to trimethoprim and sulfamethoxazole in Pseudomonas aeruginosa. Antimicrob Agents Chemother 40: 2288-2290.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 2288-2290
    • Köhler, T.1    Kok, M.2    Michea-Hamzehpour, M.3    Plesiat, P.4    Gotoh, N.5
  • 12
    • 0032906825 scopus 로고    scopus 로고
    • Resistance to beta-lactam antibiotics in Pseudomonas aeruginosa due to interplay between the MexAB-OprM efflux pump and beta-lactamase
    • Nakae T, Nakajima A, Ono T, Saito K, Yoneyama H, (1999) Resistance to beta-lactam antibiotics in Pseudomonas aeruginosa due to interplay between the MexAB-OprM efflux pump and beta-lactamase. Antimicrob Agents Chemother 43: 1301-1303.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 1301-1303
    • Nakae, T.1    Nakajima, A.2    Ono, T.3    Saito, K.4    Yoneyama, H.5
  • 13
    • 0035992752 scopus 로고    scopus 로고
    • High-level fluoroquinolone resistance in Pseudomonas aeruginosa due to interplay of the MexAB-OprM efflux pump and the DNA gyrase mutation
    • Nakajima A, Sugimoto K, Yoneyama H, Nakae T, (2002) High-level fluoroquinolone resistance in Pseudomonas aeruginosa due to interplay of the MexAB-OprM efflux pump and the DNA gyrase mutation. Microbiol Immunol 46: 391-395.
    • (2002) Microbiol Immunol , vol.46 , pp. 391-395
    • Nakajima, A.1    Sugimoto, K.2    Yoneyama, H.3    Nakae, T.4
  • 15
    • 0029129966 scopus 로고
    • Role of mexA-mexB-oprM in antibiotic efflux in Pseudomonas aeruginosa
    • Li XZ, Nikaido H, Poole K, (1995) Role of mexA-mexB-oprM in antibiotic efflux in Pseudomonas aeruginosa. Antimicrob Agents Chemother 39: 1948-1953.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 1948-1953
    • Li, X.Z.1    Nikaido, H.2    Poole, K.3
  • 16
    • 0242648332 scopus 로고    scopus 로고
    • Overexpression of the mexC-mexD-oprJ effux operon in nfxB-type multidrug resistant strains
    • Poole K, Gotoh N, Tsujimoto H, Zhao Q, Wada A, et al. (1996) Overexpression of the mexC-mexD-oprJ effux operon in nfxB-type multidrug resistant strains. Mol Microbiol 21: 713-724.
    • (1996) Mol Microbiol , vol.21 , pp. 713-724
    • Poole, K.1    Gotoh, N.2    Tsujimoto, H.3    Zhao, Q.4    Wada, A.5
  • 17
    • 0031016991 scopus 로고    scopus 로고
    • Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa
    • Köhler T, Michea-Hamzehpour M, Henze U, Gotoh N, Curty LK, et al. (1997) Characterization of MexE-MexF-OprN, a positively regulated multidrug efflux system of Pseudomonas aeruginosa. Mol Microbiol 23: 345-354.
    • (1997) Mol Microbiol , vol.23 , pp. 345-354
    • Köhler, T.1    Michea-Hamzehpour, M.2    Henze, U.3    Gotoh, N.4    Curty, L.K.5
  • 18
    • 0036667424 scopus 로고    scopus 로고
    • Characterization of a new efflux pump, MexGHI-OpmD, from Pseudomonas aeruginosa that confers resistance to vanadium
    • Aendekerk S, Ghysels B, Cornelis P, Baysse C, (2002) Characterization of a new efflux pump, MexGHI-OpmD, from Pseudomonas aeruginosa that confers resistance to vanadium. Microbiology 148: 2371-2381.
    • (2002) Microbiology , vol.148 , pp. 2371-2381
    • Aendekerk, S.1    Ghysels, B.2    Cornelis, P.3    Baysse, C.4
  • 19
    • 0036723860 scopus 로고    scopus 로고
    • The MexJK efflux pump of Pseudomonas aeruginosa requires OprM for antibiotic efflux but not for efflux of triclosan
    • Chuanchuen R, Narasaki CT, Schweizer HP, (2002) The MexJK efflux pump of Pseudomonas aeruginosa requires OprM for antibiotic efflux but not for efflux of triclosan. J Bacteriol 184: 5036-5044.
    • (2002) J Bacteriol , vol.184 , pp. 5036-5044
    • Chuanchuen, R.1    Narasaki, C.T.2    Schweizer, H.P.3
  • 20
    • 28044451986 scopus 로고    scopus 로고
    • Gene cloning and properties of the RND-type multidrug efflux pumps MexPQ-OpmE and MexMN-OprM from Pseudomonas aeruginosa
    • Mima T, Sekiya H, Mizushima T, Kuroda T, Tsuchiya T, (2005) Gene cloning and properties of the RND-type multidrug efflux pumps MexPQ-OpmE and MexMN-OprM from Pseudomonas aeruginosa. Microbiol Immunol 49: 999-1002.
    • (2005) Microbiol Immunol , vol.49 , pp. 999-1002
    • Mima, T.1    Sekiya, H.2    Mizushima, T.3    Kuroda, T.4    Tsuchiya, T.5
  • 21
    • 0141963102 scopus 로고    scopus 로고
    • A new member of the tripartite multidrug efflux pumps, MexVW-OprM, in Pseudomonas aeruginosa
    • Li Y, Mima T, Komori Y, Morita Y, Kuroda T, et al. (2003) A new member of the tripartite multidrug efflux pumps, MexVW-OprM, in Pseudomonas aeruginosa. J Antimicrob Chemother 52: 572-575.
    • (2003) J Antimicrob Chemother , vol.52 , pp. 572-575
    • Li, Y.1    Mima, T.2    Komori, Y.3    Morita, Y.4    Kuroda, T.5
  • 22
    • 0032994954 scopus 로고    scopus 로고
    • Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa
    • Mine T, Morita Y, Kataoka A, Mizushima T, Tsuchiya T, (1999) Expression in Escherichia coli of a new multidrug efflux pump, MexXY, from Pseudomonas aeruginosa. Antimicrob Agents Chemother 43: 415-417.
    • (1999) Antimicrob Agents Chemother , vol.43 , pp. 415-417
    • Mine, T.1    Morita, Y.2    Kataoka, A.3    Mizushima, T.4    Tsuchiya, T.5
  • 23
    • 35648995411 scopus 로고    scopus 로고
    • Identification and characterization of TriABC-OpmH, a triclosan efflux pump of Pseudomonas aeruginosa requiring two membrane fusion proteins
    • Mima T, Joshi S, Gomez-Escalada M, Schweizer HP, (2007) Identification and characterization of TriABC-OpmH, a triclosan efflux pump of Pseudomonas aeruginosa requiring two membrane fusion proteins. J Bacteriol 189: 7600-7609.
    • (2007) J Bacteriol , vol.189 , pp. 7600-7609
    • Mima, T.1    Joshi, S.2    Gomez-Escalada, M.3    Schweizer, H.P.4
  • 24
    • 70450265183 scopus 로고    scopus 로고
    • Gene cloning and characteristics of the RND-type multidrug efflux pump MuxABC-OpmB possessing two RND components in Pseudomonas aeruginosa
    • Mima T, Kohira N, Li Y, Sekiya H, Ogawa W, et al. (2009) Gene cloning and characteristics of the RND-type multidrug efflux pump MuxABC-OpmB possessing two RND components in Pseudomonas aeruginosa. Microbiology 155: 3509-3517.
    • (2009) Microbiology , vol.155 , pp. 3509-3517
    • Mima, T.1    Kohira, N.2    Li, Y.3    Sekiya, H.4    Ogawa, W.5
  • 25
    • 0344131941 scopus 로고    scopus 로고
    • Characterization of MexT, the regulator of the mexE-mexF-oprN multidrug efflux system of Pseudomonas aeruginosa
    • Köhler T, Epp SF, Curty LK, Pechere J-C, (1999) Characterization of MexT, the regulator of the mexE-mexF-oprN multidrug efflux system of Pseudomonas aeruginosa. J Bacteriol 181: 6300-6305.
    • (1999) J Bacteriol , vol.181 , pp. 6300-6305
    • Köhler, T.1    Epp, S.F.2    Curty, L.K.3    Pechere, J.-C.4
  • 27
    • 14544299583 scopus 로고    scopus 로고
    • Mutations in PA2491 (mexS) promote MexT-dependent mexEF-oprN expression and multidrug resistance in a clinical strain of Pseudomonas aeruginosa
    • Sobel ML, Neshat S, Poole K, (2005) Mutations in PA2491 (mexS) promote MexT-dependent mexEF-oprN expression and multidrug resistance in a clinical strain of Pseudomonas aeruginosa. J Bacteriol 187: 1246-1253.
    • (2005) J Bacteriol , vol.187 , pp. 1246-1253
    • Sobel, M.L.1    Neshat, S.2    Poole, K.3
  • 28
    • 0034333389 scopus 로고    scopus 로고
    • Variation of the mexT gene, a regulator of the MexEF-OprN efflux pump expression in wild-type strains of Pseudomonas aeruginosa
    • Maseda H, Saito K, Nakajima A, Nakae T, (2000) Variation of the mexT gene, a regulator of the MexEF-OprN efflux pump expression in wild-type strains of Pseudomonas aeruginosa. FEMS Microbiol Lett 192: 107-112.
    • (2000) FEMS Microbiol Lett , vol.192 , pp. 107-112
    • Maseda, H.1    Saito, K.2    Nakajima, A.3    Nakae, T.4
  • 29
    • 33645099316 scopus 로고    scopus 로고
    • mvaT mutation modifies the expression of the Pseudomonas aeruginosa multidrug efflux operon mexEF-oprN
    • Westfall LW, Carty NL, Layland N, Kuan P, Colmer-Hamood JA, et al. (2006) mvaT mutation modifies the expression of the Pseudomonas aeruginosa multidrug efflux operon mexEF-oprN. FEMS Microbiol Lett 255: 247-254.
    • (2006) FEMS Microbiol Lett , vol.255 , pp. 247-254
    • Westfall, L.W.1    Carty, N.L.2    Layland, N.3    Kuan, P.4    Colmer-Hamood, J.A.5
  • 30
    • 0034871821 scopus 로고    scopus 로고
    • Overexpression of the MexEF-OprN multidrug efflux system affects cell-to-cell signaling in Pseudomonas aeruginosa
    • Köhler T, van Delden C, Curty LK, Hamzehpour MM, Pechere J-C, (2001) Overexpression of the MexEF-OprN multidrug efflux system affects cell-to-cell signaling in Pseudomonas aeruginosa. J Bacteriol 183: 5213-5222.
    • (2001) J Bacteriol , vol.183 , pp. 5213-5222
    • Köhler, T.1    van Delden, C.2    Curty, L.K.3    Hamzehpour, M.M.4    Pechere, J.-C.5
  • 31
    • 78650907947 scopus 로고    scopus 로고
    • MexT regulates the type III secretion system through MexS and PtrC in Pseudomonas aeruginosa
    • Jin Y, Yang H, Qiao M, Jin S, (2011) MexT regulates the type III secretion system through MexS and PtrC in Pseudomonas aeruginosa. J Bacteriol 193: 399-410.
    • (2011) J Bacteriol , vol.193 , pp. 399-410
    • Jin, Y.1    Yang, H.2    Qiao, M.3    Jin, S.4
  • 32
    • 0035143255 scopus 로고    scopus 로고
    • Differential selection of multidrug efflux mutants by trovafloxacin and ciprofloxacin in anexperimental model of Pseudomonas aeruginosa acute pneumonia in rats
    • Join-Lambert OF, Michea-Hamzehpour M, Köhler T, Chau F, Faurisson F, et al. (2001) Differential selection of multidrug efflux mutants by trovafloxacin and ciprofloxacin in anexperimental model of Pseudomonas aeruginosa acute pneumonia in rats. Antimicrob Agents Chemother 45: 571-576.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 571-576
    • Join-Lambert, O.F.1    Michea-Hamzehpour, M.2    Köhler, T.3    Chau, F.4    Faurisson, F.5
  • 33
    • 78751684152 scopus 로고    scopus 로고
    • mexEF-oprN multidrug efflux operon of Pseudomonas aeruginosa: regulation by the MexT activator in response to nitrosative stress and chloramphenicol
    • Fetar H, Gilmour C, Klinoski R, Daigle DM, Dean CR, et al. (2011) mexEF-oprN multidrug efflux operon of Pseudomonas aeruginosa: regulation by the MexT activator in response to nitrosative stress and chloramphenicol. Antimicrob Agents Chemother 55: 508-514.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 508-514
    • Fetar, H.1    Gilmour, C.2    Klinoski, R.3    Daigle, D.M.4    Dean, C.R.5
  • 34
    • 13144257722 scopus 로고    scopus 로고
    • A novel two-component system controls the expression of Pseudomonas aeruginosa fimbrial cup genes
    • Kulasekara HD, Ventre I, Kulasekara BR, Lazdunski A, Filloux A, et al. (2005) A novel two-component system controls the expression of Pseudomonas aeruginosa fimbrial cup genes. Mol Microbiol 55: 368-380.
    • (2005) Mol Microbiol , vol.55 , pp. 368-380
    • Kulasekara, H.D.1    Ventre, I.2    Kulasekara, B.R.3    Lazdunski, A.4    Filloux, A.5
  • 35
    • 77956408650 scopus 로고    scopus 로고
    • Transcriptional regulation of the mexEF-oprN multidrug efflux pump operon by MexT and an unidentified repressor in nfxC-type mutant of Pseudomonas aeruginosa
    • Maseda H, Uwate M, Nakae T, (2010) Transcriptional regulation of the mexEF-oprN multidrug efflux pump operon by MexT and an unidentified repressor in nfxC-type mutant of Pseudomonas aeruginosa. FEMS Microbiology Letters 311: 36-43.
    • (2010) FEMS Microbiology Letters , vol.311 , pp. 36-43
    • Maseda, H.1    Uwate, M.2    Nakae, T.3
  • 36
    • 18244370493 scopus 로고    scopus 로고
    • Substrate-dependent utilization of OprM or OpmH by the Pseudomonas aeruginosa MexJK efflux pump
    • Chuanchuen R, Murata T, Gotoh N, Schweizer HP, (2005) Substrate-dependent utilization of OprM or OpmH by the Pseudomonas aeruginosa MexJK efflux pump. Antimicrob Agents Chemother 49: 2133-2136.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 2133-2136
    • Chuanchuen, R.1    Murata, T.2    Gotoh, N.3    Schweizer, H.P.4
  • 38
    • 0026571761 scopus 로고
    • Allelic exchange in Pseudomonas aeruginosa using novel ColE1-type vectors and a family of cassettes containing a portable oriT and the counter-selectable Bacillus subtilis sacB marker
    • Schweizer HP, (1992) Allelic exchange in Pseudomonas aeruginosa using novel ColE1-type vectors and a family of cassettes containing a portable oriT and the counter-selectable Bacillus subtilis sacB marker. Mol Microbiol 6: 1195-1204.
    • (1992) Mol Microbiol , vol.6 , pp. 1195-1204
    • Schweizer, H.P.1
  • 39
    • 32244448730 scopus 로고    scopus 로고
    • A 10-min method for preparation of highly electrocompetent Pseudomonas aeruginosa cells: application for DNA fragment transfer between chromosomes and plasmid transformation
    • Choi KH, Kumar A, Schweizer HP, (2006) A 10-min method for preparation of highly electrocompetent Pseudomonas aeruginosa cells: application for DNA fragment transfer between chromosomes and plasmid transformation. J Microbiol Methods 64: 391-397.
    • (2006) J Microbiol Methods , vol.64 , pp. 391-397
    • Choi, K.H.1    Kumar, A.2    Schweizer, H.P.3
  • 40
    • 33749531431 scopus 로고    scopus 로고
    • mini-Tn7 insertion in bacteria with single attTn7 sites: example Pseudomonas aeruginosa
    • Choi KH, Schweizer HP, (2006) mini-Tn7 insertion in bacteria with single attTn7 sites: example Pseudomonas aeruginosa. Nat Protoc 1: 153-161.
    • (2006) Nat Protoc , vol.1 , pp. 153-161
    • Choi, K.H.1    Schweizer, H.P.2
  • 41
    • 23044461889 scopus 로고    scopus 로고
    • An improved method for rapid generation of unmarked Pseudomonas aeruginosa deletion mutants
    • Choi KH, Schweizer HP, (2005) An improved method for rapid generation of unmarked Pseudomonas aeruginosa deletion mutants. BMC Microbiol 5: 30.
    • (2005) BMC Microbiol , vol.5 , pp. 30
    • Choi, K.H.1    Schweizer, H.P.2
  • 42
    • 0037137283 scopus 로고    scopus 로고
    • Characterization of outer membrane efflux proteins OpmE, OpmD and OpmB of Pseudomonas aeruginosa: molecular cloning and development of specific antisera
    • Murata T, Gotoh N, Nishino T, (2002) Characterization of outer membrane efflux proteins OpmE, OpmD and OpmB of Pseudomonas aeruginosa: molecular cloning and development of specific antisera. FEMS Microbiol Lett 217: 57-63.
    • (2002) FEMS Microbiol Lett , vol.217 , pp. 57-63
    • Murata, T.1    Gotoh, N.2    Nishino, T.3
  • 43
    • 0033968474 scopus 로고    scopus 로고
    • Integration proficient plasmids for Pseudomonas aeruginosa: site-specific integration and use for engineering of reporter and expression strains
    • Hoang TT, Kutchma AJ, Becher A, Schweizer HP, (2000) Integration proficient plasmids for Pseudomonas aeruginosa: site-specific integration and use for engineering of reporter and expression strains. Plasmid 43: 59-72.
    • (2000) Plasmid , vol.43 , pp. 59-72
    • Hoang, T.T.1    Kutchma, A.J.2    Becher, A.3    Schweizer, H.P.4
  • 44
    • 0003785155 scopus 로고
    • Cold Spring Habor, NY, Cold Spring Habor Laboratory Press
    • Miller JH, (1972) Experiments in Molecular Genetics Cold Spring Habor, NY Cold Spring Habor Laboratory Press.
    • (1972) Experiments in Molecular Genetics
    • Miller, J.H.1
  • 45
    • 0028172499 scopus 로고
    • Construction of improved Escherichia-Pseudomonas shuttle vectors derived from pUC18/19 and the sequence of the region required for their replication in Pseudomonas aeruginosa
    • West SEH, Schweizer HP, Dall C, Sample AK, Runyen-Janecky LJ, (1994) Construction of improved Escherichia-Pseudomonas shuttle vectors derived from pUC18/19 and the sequence of the region required for their replication in Pseudomonas aeruginosa. Gene 128: 81-86.
    • (1994) Gene , vol.128 , pp. 81-86
    • West, S.E.H.1    Schweizer, H.P.2    Dall, C.3    Sample, A.K.4    Runyen-Janecky, L.J.5
  • 46
    • 0345129808 scopus 로고
    • Genetic maps
    • In: O'Brien SJ, editors, Cold Spring Harbor, Cold Spring Harbor Laboratory Press
    • Holloway BW, Zhang C, (1990) Genetic maps. In: O'Brien SJ, editors. Locus Maps of Complex Genomes. 5 ed Cold Spring Harbor Cold Spring Harbor Laboratory Press pp. 2.71-72.78.
    • (1990) Locus Maps of Complex Genomes. 5 Ed , pp. 7271-7278
    • Holloway, B.W.1    Zhang, C.2


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