The role of endosomal escape and mitogen-activated protein kinases in adenoviral activation of the innate immune response

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Smith, Jeffrey S ^a   Xu, Zhili ^a   Tian, Jie ^a   Palmer, Donna J ^b   Ng, Philip ^b   Byrnes, Andrew P ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CHEMOKINE; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHOTRANSFERASE INHIBITOR; RANTES; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RESPONSE; ENDOSOME; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; INNATE IMMUNITY; MALE; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; TRANSGENE; VIRION; VIRUS ACTIVATION; VIRUS GENE; VIRUS MUTANT; ADENOVIRUS; ANIMAL; GENE VECTOR; GENETICS; IMMUNOLOGY; METABOLISM;

MUS;

ADENOVIRIDAE; ANIMALS; CHEMOKINES; CYTOKINES; ENDOSOMES; GENETIC VECTORS; IMMUNITY, INNATE; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES;

EID: 80055032487     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026755     Document Type: Article

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