Rac1-regulated dendritic spine remodeling contributes to neuropathic pain after peripheral nerve injury

Experimental Neurology

Volumn 232, Issue 2, 2011, Pages 222-233

  Tan, Andrew M ^a,b   Chang, Yu Wen ^a,b   Zhao, Peng ^a,b   Hains, Bryan C ^a,b   Waxman, Stephen G ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

Author keywords

Central sensitization; Dendritic spines; Neuropathic pain; Peripheral nerve injury; Wide dynamic range neurons

Indexed keywords

4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; PROTEIN INHIBITOR; RAC1 PROTEIN;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASSAY; BEHAVIOR; CELL STRUCTURE; CONTROLLED STUDY; DENDRITIC SPINE; HINDLIMB; HYPERALGESIA; MALE; NERVE CELL EXCITABILITY; NERVE INJURY; NEUROPATHIC PAIN; NOCICEPTIVE STIMULATION; NONHUMAN; PAIN THRESHOLD; PATHOGENESIS; PERIKARYON; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SHAM PROCEDURE; SINGLE UNIT ACTIVITY; SPINAL CORD DORSAL HORN; SPINAL CORD NERVE CELL; STIMULUS RESPONSE; SYNAPSE; SYNAPTIC TRANSMISSION;

AMINOQUINOLINES; ANIMALS; CELLS, CULTURED; CHRONIC DISEASE; DENDRITIC SPINES; ENZYME INHIBITORS; FEMALE; MALE; NEURALGIA; NOCICEPTORS; PERIPHERAL NERVE INJURIES; POSTERIOR HORN CELLS; PREGNANCY; PYRIMIDINES; RAC1 GTP-BINDING PROTEIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 80055016478     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.08.028     Document Type: Article

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