-
1
-
-
67650689649
-
Significance of nitroimidazole compounds and hypoxia-inducible factor-1 for imaging tumor hypoxia
-
Kizaka-Kondoh S, Konse-Nagasawa H. Significance of nitroimidazole compounds and hypoxia-inducible factor-1 for imaging tumor hypoxia. Cancer Sci 2009; 100: 1366-73.
-
(2009)
Cancer Sci
, vol.100
, pp. 1366-1373
-
-
Kizaka-Kondoh, S.1
Konse-Nagasawa, H.2
-
2
-
-
0033571682
-
Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases
-
Zhong H, De Marzo AM, Laughner E et al. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases. Cancer Res 1999; 59: 5830-5.
-
(1999)
Cancer Res
, vol.59
, pp. 5830-5835
-
-
Zhong, H.1
De Marzo, A.M.2
Laughner, E.3
-
3
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003; 3: 721-32.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
4
-
-
66449118481
-
The selective hypoxia inducible factor-1 inhibitor PX-478 provides in vivo radiosensitization through tumor stromal effects
-
Schwartz DL, Powis G, Thitai-Kumar A et al. The selective hypoxia inducible factor-1 inhibitor PX-478 provides in vivo radiosensitization through tumor stromal effects. Mol Cancer Ther 2009; 8: 947-58.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 947-958
-
-
Schwartz, D.L.1
Powis, G.2
Thitai-Kumar, A.3
-
5
-
-
65749102069
-
The HIF-1-active microenvironment: an environmental target for cancer therapy
-
Kizaka-Kondoh S, Tanaka S, Harada H, Hiraoka M. The HIF-1-active microenvironment: an environmental target for cancer therapy. Adv Drug Deliv Rev 2009; 61: 623-32.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 623-632
-
-
Kizaka-Kondoh, S.1
Tanaka, S.2
Harada, H.3
Hiraoka, M.4
-
6
-
-
4344567362
-
Molecular imaging of temporal dynamics and spatial heterogeneity of hypoxia-inducible factor-1 signal transduction activity in tumors in living mice
-
Serganova I, Doubrovin M, Vider J et al. Molecular imaging of temporal dynamics and spatial heterogeneity of hypoxia-inducible factor-1 signal transduction activity in tumors in living mice. Cancer Res 2004; 64: 6101-8.
-
(2004)
Cancer Res
, vol.64
, pp. 6101-6108
-
-
Serganova, I.1
Doubrovin, M.2
Vider, J.3
-
7
-
-
60549093719
-
Novel detector technology for clinical PET
-
Lecomte R. Novel detector technology for clinical PET. Eur J Nucl Med Mol Imaging 2009; 36 (Suppl 1): S69-85.
-
(2009)
Eur J Nucl Med Mol Imaging
, vol.36
, Issue.SUPPL. 1
-
-
Lecomte, R.1
-
8
-
-
51849109068
-
Recent developments in PET detector technology
-
Lewellen TK. Recent developments in PET detector technology. Phys Med Biol 2008; 53: R287-317.
-
(2008)
Phys Med Biol
, vol.53
-
-
Lewellen, T.K.1
-
10
-
-
41549110644
-
Small-animal preclinical nuclear medicine instrumentation and methodology
-
Rowland DJ, Cherry SR. Small-animal preclinical nuclear medicine instrumentation and methodology. Semin Nucl Med 2008; 38: 209-22.
-
(2008)
Semin Nucl Med
, vol.38
, pp. 209-222
-
-
Rowland, D.J.1
Cherry, S.R.2
-
12
-
-
42949106526
-
Rapid degradation of hypoxia-inducible factor-1alpha by KRH102053, a new activator of prolyl hydroxylase 2
-
Choi HJ, Song BJ, Gong YD, Gwak WJ, Soh Y. Rapid degradation of hypoxia-inducible factor-1alpha by KRH102053, a new activator of prolyl hydroxylase 2. Br J Pharmacol 2008; 154: 114-25.
-
(2008)
Br J Pharmacol
, vol.154
, pp. 114-125
-
-
Choi, H.J.1
Song, B.J.2
Gong, Y.D.3
Gwak, W.J.4
Soh, Y.5
-
13
-
-
66149164442
-
Selective killing of hypoxia-inducible factor-1-active cells improves survival in a mouse model of invasive and metastatic pancreatic cancer
-
Kizaka-Kondoh S, Itasaka S, Zeng L et al. Selective killing of hypoxia-inducible factor-1-active cells improves survival in a mouse model of invasive and metastatic pancreatic cancer. Clin Cancer Res 2009; 15: 3433-41.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 3433-3441
-
-
Kizaka-Kondoh, S.1
Itasaka, S.2
Zeng, L.3
-
14
-
-
66649093239
-
Imaging of HIF-1-active tumor hypoxia using a protein effectively delivered to and specifically stabilized in HIF-1-active tumor cells
-
Kudo T, Ueda M, Kuge Y et al. Imaging of HIF-1-active tumor hypoxia using a protein effectively delivered to and specifically stabilized in HIF-1-active tumor cells. J Nucl Med 2009; 50: 942-9.
-
(2009)
J Nucl Med
, vol.50
, pp. 942-949
-
-
Kudo, T.1
Ueda, M.2
Kuge, Y.3
-
15
-
-
77956181702
-
Rapid detection of hypoxia-inducible factor-1-active tumours: pretargeted imaging with a protein degrading in a mechanism similar to hypoxia-inducible factor-1alpha
-
Ueda M, Kudo T, Kuge Y et al. Rapid detection of hypoxia-inducible factor-1-active tumours: pretargeted imaging with a protein degrading in a mechanism similar to hypoxia-inducible factor-1alpha. Eur J Nucl Med Mol Imaging 2010; 37: 1566-74.
-
(2010)
Eur J Nucl Med Mol Imaging
, vol.37
, pp. 1566-1574
-
-
Ueda, M.1
Kudo, T.2
Kuge, Y.3
-
16
-
-
77949416116
-
Nicotinic acetylcholine receptors expressed in the ventralposterolateral thalamic nucleus play an important role in anti-allodynic effects
-
Ueda M, Iida Y, Tominaga A et al. Nicotinic acetylcholine receptors expressed in the ventralposterolateral thalamic nucleus play an important role in anti-allodynic effects. Br J Pharmacol 2010; 159: 1201-10.
-
(2010)
Br J Pharmacol
, vol.159
, pp. 1201-1210
-
-
Ueda, M.1
Iida, Y.2
Tominaga, A.3
-
17
-
-
78651294978
-
Tissue factor detection for selectively discriminating unstable plaques in an atherosclerotic rabbit model
-
Temma T, Ogawa Y, Kuge Y et al. Tissue factor detection for selectively discriminating unstable plaques in an atherosclerotic rabbit model. J Nucl Med 2010; 51: 1979-86.
-
(2010)
J Nucl Med
, vol.51
, pp. 1979-1986
-
-
Temma, T.1
Ogawa, Y.2
Kuge, Y.3
-
18
-
-
84855715652
-
PET imaging of hypoxia-inducible factor-1-active tumor cells with pretargeted oxygen-dependent degradable streptavidin and a novel (18)F-labeled biotin derivative
-
[Epub ahead of print].
-
Kudo T, Ueda M, Konishi H et al. PET imaging of hypoxia-inducible factor-1-active tumor cells with pretargeted oxygen-dependent degradable streptavidin and a novel (18)F-labeled biotin derivative. Mol Imaging Biol 2010; [Epub ahead of print].
-
(2010)
Mol Imaging Biol
-
-
Kudo, T.1
Ueda, M.2
Konishi, H.3
-
19
-
-
0025109434
-
Metabolism of indium-111-labeled murine monoclonal antibody in tumor and normal tissue of the athymic mouse
-
Motta-Hennessy C, Sharkey RM, Goldenberg DM. Metabolism of indium-111-labeled murine monoclonal antibody in tumor and normal tissue of the athymic mouse. J Nucl Med 1990; 31: 1510-9.
-
(1990)
J Nucl Med
, vol.31
, pp. 1510-1519
-
-
Motta-Hennessy, C.1
Sharkey, R.M.2
Goldenberg, D.M.3
-
21
-
-
66149090004
-
Radiopharmaceuticals in preclinical and clinical development for monitoring of therapy with PET
-
Dunphy MP, Lewis JS. Radiopharmaceuticals in preclinical and clinical development for monitoring of therapy with PET. J Nucl Med 2009; 50 (Suppl 1): 106S-21S.
-
(2009)
J Nucl Med
, vol.50
, Issue.SUPPL. 1
-
-
Dunphy, M.P.1
Lewis, J.S.2
-
24
-
-
51349106946
-
Visualization of hypoxia-inducible factor-1 transcriptional activation in C6 glioma using luciferase and sodium iodide symporter genes
-
Yeom CJ, Chung JK, Kang JH et al. Visualization of hypoxia-inducible factor-1 transcriptional activation in C6 glioma using luciferase and sodium iodide symporter genes. J Nucl Med 2008; 49: 1489-97.
-
(2008)
J Nucl Med
, vol.49
, pp. 1489-1497
-
-
Yeom, C.J.1
Chung, J.K.2
Kang, J.H.3
-
25
-
-
54249165055
-
Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers
-
He F, Deng X, Wen B et al. Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers. Cancer Res 2008; 68: 8597-606.
-
(2008)
Cancer Res
, vol.68
, pp. 8597-8606
-
-
He, F.1
Deng, X.2
Wen, B.3
-
26
-
-
69249215186
-
In vivo characterization of a reporter gene system for imaging hypoxia-induced gene expression
-
Carlin S, Pugachev A, Sun X et al. In vivo characterization of a reporter gene system for imaging hypoxia-induced gene expression. Nucl Med Biol 2009; 36: 821-31.
-
(2009)
Nucl Med Biol
, vol.36
, pp. 821-831
-
-
Carlin, S.1
Pugachev, A.2
Sun, X.3
-
27
-
-
34447565882
-
The combination of hypoxia-response enhancers and an oxygen-dependent proteolytic motif enables real-time imaging of absolute HIF-1 activity in tumor xenografts
-
Harada H, Kizaka-Kondoh S, Itasaka S et al. The combination of hypoxia-response enhancers and an oxygen-dependent proteolytic motif enables real-time imaging of absolute HIF-1 activity in tumor xenografts. Biochem Biophys Res Commun 2007; 360: 791-6.
-
(2007)
Biochem Biophys Res Commun
, vol.360
, pp. 791-796
-
-
Harada, H.1
Kizaka-Kondoh, S.2
Itasaka, S.3
-
28
-
-
64549134226
-
Real-time imaging of HIF-1alpha stabilization and degradation
-
Moroz E, Carlin S, Dyomina K et al. Real-time imaging of HIF-1alpha stabilization and degradation. PLoS One 2009; 4: e5077.
-
(2009)
PLoS One
, vol.4
-
-
Moroz, E.1
Carlin, S.2
Dyomina, K.3
-
29
-
-
78650824227
-
In vivo imaging of HIF-active tumors by an oxygen-dependent degradation protein probe with an interchangeable labeling system
-
Kuchimaru T, Kadonosono T, Tanaka S, Ushiki T, Hiraoka M, Kizaka-Kondoh S. In vivo imaging of HIF-active tumors by an oxygen-dependent degradation protein probe with an interchangeable labeling system. PLoS One 2010; 5: e15736.
-
(2010)
PLoS One
, vol.5
-
-
Kuchimaru, T.1
Kadonosono, T.2
Tanaka, S.3
Ushiki, T.4
Hiraoka, M.5
Kizaka-Kondoh, S.6
-
30
-
-
62949231036
-
Small animal imaging facility: new perspectives for the radiologist
-
Grassi R, Cavaliere C, Cozzolino S et al. Small animal imaging facility: new perspectives for the radiologist. Radiol Med 2009; 114: 152-67.
-
(2009)
Radiol Med
, vol.114
, pp. 152-167
-
-
Grassi, R.1
Cavaliere, C.2
Cozzolino, S.3
-
31
-
-
68949220221
-
Targeting murine heart and brain: visualisation conditions for multi-pinhole SPECT with (99m)Tc- and (123)I-labelled probes
-
Pissarek M, Meyer-Kirchrath J, Hohlfeld T et al. Targeting murine heart and brain: visualisation conditions for multi-pinhole SPECT with (99m)Tc- and (123)I-labelled probes. Eur J Nucl Med Mol Imaging 2009; 36: 1495-509.
-
(2009)
Eur J Nucl Med Mol Imaging
, vol.36
, pp. 1495-1509
-
-
Pissarek, M.1
Meyer-Kirchrath, J.2
Hohlfeld, T.3
-
32
-
-
63849284181
-
U-SPECT-II: an ultra-high-resolution device for molecular small-animal imaging
-
van der Have F, Vastenhouw B, Ramakers RM et al. U-SPECT-II: an ultra-high-resolution device for molecular small-animal imaging. J Nucl Med 2009; 50: 599-605.
-
(2009)
J Nucl Med
, vol.50
, pp. 599-605
-
-
van der Have, F.1
Vastenhouw, B.2
Ramakers, R.M.3
-
33
-
-
69549138474
-
Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events
-
Lehmann S, Stiehl DP, Honer M et al. Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events. Proc Natl Acad Sci U S A 2009; 106: 14004-9.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14004-14009
-
-
Lehmann, S.1
Stiehl, D.P.2
Honer, M.3
-
34
-
-
34548018979
-
Visualization of hypoxia in microscopic tumors by immunofluorescent microscopy
-
Li XF, Carlin S, Urano M, Russell J, Ling CC, O'Donoghue JA. Visualization of hypoxia in microscopic tumors by immunofluorescent microscopy. Cancer Res 2007; 67: 7646-53.
-
(2007)
Cancer Res
, vol.67
, pp. 7646-7653
-
-
Li, X.F.1
Carlin, S.2
Urano, M.3
Russell, J.4
Ling, C.C.5
O'Donoghue, J.A.6
-
35
-
-
23844485492
-
Reduced expression of hypoxia-inducible factor-1alpha in perinecrotic regions of solid tumors
-
Sobhanifar S, Aquino-Parsons C, Stanbridge EJ, Olive P. Reduced expression of hypoxia-inducible factor-1alpha in perinecrotic regions of solid tumors. Cancer Res 2005; 65: 7259-66.
-
(2005)
Cancer Res
, vol.65
, pp. 7259-7266
-
-
Sobhanifar, S.1
Aquino-Parsons, C.2
Stanbridge, E.J.3
Olive, P.4
-
36
-
-
79959365312
-
Mechanisms of cellular uptake of cell-penetrating peptides
-
Madani F, Lindberg S, Langel U, Futaki S, Graslund A. Mechanisms of cellular uptake of cell-penetrating peptides. J Biophys 2011; 2011: 414729.
-
(2011)
J Biophys
, vol.2011
, pp. 414729
-
-
Madani, F.1
Lindberg, S.2
Langel, U.3
Futaki, S.4
Graslund, A.5
-
37
-
-
38949188925
-
Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides
-
Nakase I, Takeuchi T, Tanaka G, Futaki S. Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides. Adv Drug Deliv Rev 2008; 60: 598-607.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 598-607
-
-
Nakase, I.1
Takeuchi, T.2
Tanaka, G.3
Futaki, S.4
-
38
-
-
73349115905
-
Construction of mutant TKGFP for real-time imaging of temporal dynamics of HIF-1 signal transduction activity mediated by hypoxia and reoxygenation in tumors in living mice
-
Hsieh CH, Kuo JW, Lee YJ, Chang CW, Gelovani JG, Liu RS. Construction of mutant TKGFP for real-time imaging of temporal dynamics of HIF-1 signal transduction activity mediated by hypoxia and reoxygenation in tumors in living mice. J Nucl Med 2009; 50: 2049-57.
-
(2009)
J Nucl Med
, vol.50
, pp. 2049-2057
-
-
Hsieh, C.H.1
Kuo, J.W.2
Lee, Y.J.3
Chang, C.W.4
Gelovani, J.G.5
Liu, R.S.6
-
39
-
-
9944256262
-
A preclinical model for noninvasive imaging of hypoxia-induced gene expression; comparison with an exogenous marker of tumor hypoxia
-
Wen B, Burgman P, Zanzonico P et al. A preclinical model for noninvasive imaging of hypoxia-induced gene expression; comparison with an exogenous marker of tumor hypoxia. Eur J Nucl Med Mol Imaging 2004; 31: 1530-8.
-
(2004)
Eur J Nucl Med Mol Imaging
, vol.31
, pp. 1530-1538
-
-
Wen, B.1
Burgman, P.2
Zanzonico, P.3
|