-
1
-
-
0017879170
-
Enhanced binding by cultured human fibroblasts of apo-E-containing lipoproteins as compared with low density lipoproteins
-
Innerarity T.L., Mahley R.W. Enhanced binding by cultured human fibroblasts of apo-E-containing lipoproteins as compared with low density lipoproteins. Biochemistry 1978, 17:1440-1447.
-
(1978)
Biochemistry
, vol.17
, pp. 1440-1447
-
-
Innerarity, T.L.1
Mahley, R.W.2
-
2
-
-
0028917252
-
Lipoprotein and receptor interactions in vivo
-
Herz J., Willnow T.E. Lipoprotein and receptor interactions in vivo. Curr Opin Lipidol 1995, 6:97-103.
-
(1995)
Curr Opin Lipidol
, vol.6
, pp. 97-103
-
-
Herz, J.1
Willnow, T.E.2
-
3
-
-
0026693345
-
Characterization and immunohistochemical localization of alpha 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain
-
Wolf B.B., Lopes M.B., VandenBerg S.R., Gonias S.L. Characterization and immunohistochemical localization of alpha 2-macroglobulin receptor (low-density lipoprotein receptor-related protein) in human brain. Am J Pathol 1992, 141:37-42.
-
(1992)
Am J Pathol
, vol.141
, pp. 37-42
-
-
Wolf, B.B.1
Lopes, M.B.2
VandenBerg, S.R.3
Gonias, S.L.4
-
4
-
-
0029922119
-
Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain
-
Kim D.H., Iijima H., Goto K., et al. Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain. J Biol Chem 1996, 271:8373-8380.
-
(1996)
J Biol Chem
, vol.271
, pp. 8373-8380
-
-
Kim, D.H.1
Iijima, H.2
Goto, K.3
-
5
-
-
0026778830
-
Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity
-
Takahashi S., Kawarabayasi Y., Nakai T., et al. Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity. Proc Natl Acad Sci U S A 1992, 89:9252-9256.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 9252-9256
-
-
Takahashi, S.1
Kawarabayasi, Y.2
Nakai, T.3
-
6
-
-
0032839621
-
Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond
-
Mahley R.W., Huang Y. Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond. Curr Opin Lipidol 1999, 10:207-217.
-
(1999)
Curr Opin Lipidol
, vol.10
, pp. 207-217
-
-
Mahley, R.W.1
Huang, Y.2
-
7
-
-
0029784503
-
Novel mechanism for defective receptor binding of apolipoprotein E2 in type III hyperlipoproteinemia
-
Dong L.M., Parkin S., Trakhanov S.D., et al. Novel mechanism for defective receptor binding of apolipoprotein E2 in type III hyperlipoproteinemia. Nat Struct Biol 1996, 3:718-722.
-
(1996)
Nat Struct Biol
, vol.3
, pp. 718-722
-
-
Dong, L.M.1
Parkin, S.2
Trakhanov, S.D.3
-
8
-
-
0023389964
-
Apolipoprotein E2-Christchurch (136 ArgcṫSer). New variant of human apolipoprotein E in a patient with type III hyperlipoproteinemia
-
Wardell M.R., Brennan S.O., Janus E.D., et al. Apolipoprotein E2-Christchurch (136 ArgcṫSer). New variant of human apolipoprotein E in a patient with type III hyperlipoproteinemia. J Clin Invest 1987, 80:483-490.
-
(1987)
J Clin Invest
, vol.80
, pp. 483-490
-
-
Wardell, M.R.1
Brennan, S.O.2
Janus, E.D.3
-
9
-
-
0024559621
-
Type III hyperlipoproteinemia associated with apolipoprotein E phenotype E3/3. Structure and genetics of an apolipoprotein E3 variant
-
Rall S.C., Newhouse Y.M., Clarke H.R., et al. Type III hyperlipoproteinemia associated with apolipoprotein E phenotype E3/3. Structure and genetics of an apolipoprotein E3 variant. J Clin Invest 1989, 83:1095-1101.
-
(1989)
J Clin Invest
, vol.83
, pp. 1095-1101
-
-
Rall, S.C.1
Newhouse, Y.M.2
Clarke, H.R.3
-
10
-
-
0024820009
-
Apolipoprotein E3-Leiden contains a seven-amino acid insertion that is a tandem repeat of residues 121-127
-
Wardell M.R., Weisgraber K.H., Havekes L.M., Rall S.C. Apolipoprotein E3-Leiden contains a seven-amino acid insertion that is a tandem repeat of residues 121-127. J Biol Chem 1989, 264:21205-21210.
-
(1989)
J Biol Chem
, vol.264
, pp. 21205-21210
-
-
Wardell, M.R.1
Weisgraber, K.H.2
Havekes, L.M.3
Rall, S.C.4
-
12
-
-
0025017405
-
Genetic heterogeneity in familial dysbetalipoproteinemia. The E2(lys146cṫgln) variant results in a dominant mode of inheritance
-
Smit M., de Knijff P., Kooij-Meijs E., et al. Genetic heterogeneity in familial dysbetalipoproteinemia. The E2(lys146cṫgln) variant results in a dominant mode of inheritance. J Lipid Res 1990, 31:45-53.
-
(1990)
J Lipid Res
, vol.31
, pp. 45-53
-
-
Smit, M.1
de Knijff, P.2
Kooij-Meijs, E.3
-
13
-
-
0019820184
-
Type III hyperlipoproteinemia associated with apolipoprotein E deficiency
-
Ghiselli G., Schaefer E.J., Gascon P., Breser H.B. Type III hyperlipoproteinemia associated with apolipoprotein E deficiency. Science 1981, 214:1239-1241.
-
(1981)
Science
, vol.214
, pp. 1239-1241
-
-
Ghiselli, G.1
Schaefer, E.J.2
Gascon, P.3
Breser, H.B.4
-
14
-
-
0019379410
-
Human apolipoprotein E isoprotein subclasses are genetically determined
-
Zannis V.I., Just P.W., Breslow J.L. Human apolipoprotein E isoprotein subclasses are genetically determined. Am J Hum Genet 1981, 33:11-24.
-
(1981)
Am J Hum Genet
, vol.33
, pp. 11-24
-
-
Zannis, V.I.1
Just, P.W.2
Breslow, J.L.3
-
15
-
-
0042974264
-
Molecular mechanisms of type III hyperlipoproteinemia: the contribution of the carboxy-terminal domain of ApoE can account for the dyslipidemia that is associated with the E2/E2 phenotype
-
Kypreos K.E., Li X., Van Dijk K.W., et al. Molecular mechanisms of type III hyperlipoproteinemia: the contribution of the carboxy-terminal domain of ApoE can account for the dyslipidemia that is associated with the E2/E2 phenotype. Biochemistry 2003, 42:9841-9853.
-
(2003)
Biochemistry
, vol.42
, pp. 9841-9853
-
-
Kypreos, K.E.1
Li, X.2
Van Dijk, K.W.3
-
17
-
-
0023189466
-
The molecular basis of a familial apoE deficiency. An acceptor splice site mutation in the third intron of the deficient apoE gene
-
Cladaras C., Hadzopoulou-Cladaras M., Felber B.K., et al. The molecular basis of a familial apoE deficiency. An acceptor splice site mutation in the third intron of the deficient apoE gene. J Biol Chem 1987, 262:2310-2315.
-
(1987)
J Biol Chem
, vol.262
, pp. 2310-2315
-
-
Cladaras, C.1
Hadzopoulou-Cladaras, M.2
Felber, B.K.3
-
18
-
-
0026725757
-
Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells
-
Plump A.S., Smith J.D., Hayek T., et al. Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells. Cell 1992, 71:343-353.
-
(1992)
Cell
, vol.71
, pp. 343-353
-
-
Plump, A.S.1
Smith, J.D.2
Hayek, T.3
-
19
-
-
0026592806
-
Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
-
Zhang S.H., Reddick R.L., Piedrahita J.A., Maeda N. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 1992, 258:468-471.
-
(1992)
Science
, vol.258
, pp. 468-471
-
-
Zhang, S.H.1
Reddick, R.L.2
Piedrahita, J.A.3
Maeda, N.4
-
20
-
-
0027976942
-
Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression
-
Reddick R.L., Zhang S.H., Maeda N. Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression. Arterioscler Thromb 1994, 14:141-147.
-
(1994)
Arterioscler Thromb
, vol.14
, pp. 141-147
-
-
Reddick, R.L.1
Zhang, S.H.2
Maeda, N.3
-
21
-
-
0027174832
-
Transgenic mice carrying the apolipoprotein E3-Leiden gene exhibit hyperlipoproteinemia
-
van den Maagdenberg A.M., Hofker M.H., Krimpenfort P.J., et al. Transgenic mice carrying the apolipoprotein E3-Leiden gene exhibit hyperlipoproteinemia. J Biol Chem 1993, 268:10540-10545.
-
(1993)
J Biol Chem
, vol.268
, pp. 10540-10545
-
-
van den Maagdenberg, A.M.1
Hofker, M.H.2
Krimpenfort, P.J.3
-
22
-
-
0028105142
-
Susceptibility to diet-induced atherosclerosis in transgenic mice expressing a dysfunctional human apolipoprotein E(Arg 112,Cys142)
-
Fazio S., Sanan D.A., Lee Y.L., et al. Susceptibility to diet-induced atherosclerosis in transgenic mice expressing a dysfunctional human apolipoprotein E(Arg 112,Cys142). Arterioscler Thromb 1994, 14:1873-1879.
-
(1994)
Arterioscler Thromb
, vol.14
, pp. 1873-1879
-
-
Fazio, S.1
Sanan, D.A.2
Lee, Y.L.3
-
23
-
-
0028314348
-
Altered lipoprotein metabolism in transgenic mice expressing low levels of a human receptor-binding-defective apolipoprotein E variant
-
Fazio S., Horie Y., Simonet W.S., et al. Altered lipoprotein metabolism in transgenic mice expressing low levels of a human receptor-binding-defective apolipoprotein E variant. Lipid Res 1994, 35:408-416.
-
(1994)
Lipid Res
, vol.35
, pp. 408-416
-
-
Fazio, S.1
Horie, Y.2
Simonet, W.S.3
-
24
-
-
0029852240
-
In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158→Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice
-
van Vlijmen B.J., Van Dijk K.W., van't Hof H.B., et al. In the absence of endogenous mouse apolipoprotein E, apolipoprotein E*2(Arg-158→Cys) transgenic mice develop more severe hyperlipoproteinemia than apolipoprotein E*3-Leiden transgenic mice. J Biol Chem 1996, 271:30595-30602.
-
(1996)
J Biol Chem
, vol.271
, pp. 30595-30602
-
-
van Vlijmen, B.J.1
Van Dijk, K.W.2
van't Hof, H.B.3
-
25
-
-
0030060845
-
Plasma concentration of apolipoprotein E in intermediate-sized remnant-like lipoproteins in normolipidemic and hyperlipidemic subjects
-
Cohn J.S., Tremblay M., Amiot M., et al. Plasma concentration of apolipoprotein E in intermediate-sized remnant-like lipoproteins in normolipidemic and hyperlipidemic subjects. Arterioscler Thromb Vasc Biol 1996, 16:149-159.
-
(1996)
Arterioscler Thromb Vasc Biol
, vol.16
, pp. 149-159
-
-
Cohn, J.S.1
Tremblay, M.2
Amiot, M.3
-
26
-
-
0018133967
-
Impaired very low density lipoprotein and triglyceride removal in broad beta disease: comparison with endogenous hypertriglyceridemia
-
Chait A., Hazzard W.R., Albers J.J., et al. Impaired very low density lipoprotein and triglyceride removal in broad beta disease: comparison with endogenous hypertriglyceridemia. Metabolism 1978, 27:1055-1066.
-
(1978)
Metabolism
, vol.27
, pp. 1055-1066
-
-
Chait, A.1
Hazzard, W.R.2
Albers, J.J.3
-
27
-
-
0029808272
-
Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor, apolipoprotein E, or both
-
Ishibashi S., Perrey S., Chen Z., et al. Role of the low density lipoprotein (LDL) receptor pathway in the metabolism of chylomicron remnants. A quantitative study in knockout mice lacking the LDL receptor, apolipoprotein E, or both. J Biol Chem 1996, 271:22422-22427.
-
(1996)
J Biol Chem
, vol.271
, pp. 22422-22427
-
-
Ishibashi, S.1
Perrey, S.2
Chen, Z.3
-
28
-
-
0019217660
-
Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency
-
Havel R.J., Kotite L., Vigne J.L., et al. Radioimmunoassay of human arginine-rich apolipoprotein, apoprotein E. Concentration in blood plasma and lipoproteins as affected by apoprotein E-3 deficiency. J Clin Invest 1980, 66:1351-1362.
-
(1980)
J Clin Invest
, vol.66
, pp. 1351-1362
-
-
Havel, R.J.1
Kotite, L.2
Vigne, J.L.3
-
29
-
-
0032504182
-
Apolipoprotein E2 reduces the low density lipoprotein level in transgenic mice by impairing lipoprotein lipase-mediated lipolysis of triglyceride-rich lipoproteins
-
Huang Y., Liu X.Q., Rall S.C., Mahley R.W. Apolipoprotein E2 reduces the low density lipoprotein level in transgenic mice by impairing lipoprotein lipase-mediated lipolysis of triglyceride-rich lipoproteins. J Biol Chem 1998, 273:17483-17490.
-
(1998)
J Biol Chem
, vol.273
, pp. 17483-17490
-
-
Huang, Y.1
Liu, X.Q.2
Rall, S.C.3
Mahley, R.W.4
-
30
-
-
15644366977
-
Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia
-
Huang Y., Liu X.Q., Rall S.C., et al. Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia. J Biol Chem 1998, 273:26388-26393.
-
(1998)
J Biol Chem
, vol.273
, pp. 26388-26393
-
-
Huang, Y.1
Liu, X.Q.2
Rall, S.C.3
-
31
-
-
15844414655
-
Apolipoprotein E effectively inhibits lipoprotein lipase-mediated lipolysis of chylomicron-like triglyceride-rich lipid emulsions in vitro and in vivo
-
Rensen P.C., van Berkel T.J. Apolipoprotein E effectively inhibits lipoprotein lipase-mediated lipolysis of chylomicron-like triglyceride-rich lipid emulsions in vitro and in vivo. J Biol Chem 1996, 271:14791-14799.
-
(1996)
J Biol Chem
, vol.271
, pp. 14791-14799
-
-
Rensen, P.C.1
van Berkel, T.J.2
-
32
-
-
33644772107
-
LDL receptor deficiency or apoE mutations prevent remnant clearance and induce hypertriglyceridemia in mice
-
Kypreos K.E., Zannis V.I. LDL receptor deficiency or apoE mutations prevent remnant clearance and induce hypertriglyceridemia in mice. J Lipid Res 2006, 47:521-529.
-
(2006)
J Lipid Res
, vol.47
, pp. 521-529
-
-
Kypreos, K.E.1
Zannis, V.I.2
-
33
-
-
0035403202
-
Analysis of the structure and function relationship of the human apolipoprotein E in vivo, using adenovirus-mediated gene transfer
-
Kypreos K.E., Teusink B., Van Dijk K.W., et al. Analysis of the structure and function relationship of the human apolipoprotein E in vivo, using adenovirus-mediated gene transfer. FASEB J 2001, 15:1598-1600.
-
(2001)
FASEB J
, vol.15
, pp. 1598-1600
-
-
Kypreos, K.E.1
Teusink, B.2
Van Dijk, K.W.3
-
34
-
-
0035918518
-
The amino-terminal 1-185 domain of apoE promotes the clearance of lipoprotein remnants in vivo. The carboxy-terminal domain is required for induction of hyperlipidemia in normal and apoE-deficient mice
-
Kypreos K.E., Morani P., Van Dijk K.W., et al. The amino-terminal 1-185 domain of apoE promotes the clearance of lipoprotein remnants in vivo. The carboxy-terminal domain is required for induction of hyperlipidemia in normal and apoE-deficient mice. Biochemistry 2001, 40:6027-6035.
-
(2001)
Biochemistry
, vol.40
, pp. 6027-6035
-
-
Kypreos, K.E.1
Morani, P.2
Van Dijk, K.W.3
-
35
-
-
0035827693
-
Domains of apolipoprotein E contributing to triglyceride and cholesterol homeostasis in vivo. Carboxyl-terminal region 203-299 promotes hepatic very low density lipoprotein-triglyceride secretion
-
Kypreos K.E., Van Dijk K.W., van Der Z.A., et al. Domains of apolipoprotein E contributing to triglyceride and cholesterol homeostasis in vivo. Carboxyl-terminal region 203-299 promotes hepatic very low density lipoprotein-triglyceride secretion. J Biol Chem 2001, 276:19778-19786.
-
(2001)
J Biol Chem
, vol.276
, pp. 19778-19786
-
-
Kypreos, K.E.1
Van Dijk, K.W.2
van Der, Z.A.3
-
36
-
-
0031467633
-
Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E-deficient mouse hepatocytes
-
Kuipers F., Jong M.C., Lin Y., et al. Impaired secretion of very low density lipoprotein-triglycerides by apolipoprotein E-deficient mouse hepatocytes. J Clin Invest 1997, 100:2915-2922.
-
(1997)
J Clin Invest
, vol.100
, pp. 2915-2922
-
-
Kuipers, F.1
Jong, M.C.2
Lin, Y.3
-
37
-
-
70349496096
-
Mechanisms of obesity and related pathologies: Role of apolipoprotein E in the development of obesity
-
Kypreos K.E., Karagiannides I., Fotiadou E.H., et al. Mechanisms of obesity and related pathologies: Role of apolipoprotein E in the development of obesity. FEBS J 2009.
-
(2009)
FEBS J
-
-
Kypreos, K.E.1
Karagiannides, I.2
Fotiadou, E.H.3
-
38
-
-
34247170098
-
Pathway of biogenesis of apolipoprotein E-containing HDL in vivo with the participation of ABCA1 and LCAT
-
Kypreos K.E., Zannis V.I. Pathway of biogenesis of apolipoprotein E-containing HDL in vivo with the participation of ABCA1 and LCAT. Biochem J 2007, 403:359-367.
-
(2007)
Biochem J
, vol.403
, pp. 359-367
-
-
Kypreos, K.E.1
Zannis, V.I.2
-
39
-
-
0023687627
-
Tissue-specific posttranslational modification of rat apoE. Synthesis of sialated apoE forms by neonatal rat aortic smooth muscle cells
-
Hussain M.M., Bucher N.L., Faris B., et al. Tissue-specific posttranslational modification of rat apoE. Synthesis of sialated apoE forms by neonatal rat aortic smooth muscle cells. J Lipid Res 1988, 29:915-923.
-
(1988)
J Lipid Res
, vol.29
, pp. 915-923
-
-
Hussain, M.M.1
Bucher, N.L.2
Faris, B.3
-
40
-
-
0027330901
-
Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice
-
Li H., Reddick R.L., Maeda N. Lack of apoA-I is not associated with increased susceptibility to atherosclerosis in mice. Arterioscler Thromb 1993, 13:1814-1821.
-
(1993)
Arterioscler Thromb
, vol.13
, pp. 1814-1821
-
-
Li, H.1
Reddick, R.L.2
Maeda, N.3
-
41
-
-
14844327766
-
Generation of a recombinant apolipoprotein E variant with improved biological functions: hydrophobic residues (LEU-261, TRP-264, PHE-265, LEU-268, VAL-269) of apoE can account for the apoE-induced hypertriglyceridemia
-
Kypreos K.E., Van Dijk K.W., Havekes L.M., Zannis V.I. Generation of a recombinant apolipoprotein E variant with improved biological functions: hydrophobic residues (LEU-261, TRP-264, PHE-265, LEU-268, VAL-269) of apoE can account for the apoE-induced hypertriglyceridemia. J Biol Chem 2005, 280:6276-6284.
-
(2005)
J Biol Chem
, vol.280
, pp. 6276-6284
-
-
Kypreos, K.E.1
Van Dijk, K.W.2
Havekes, L.M.3
Zannis, V.I.4
-
42
-
-
0033983876
-
Effect of macrophage-derived mouse ApoE, human ApoE3-Leiden, and human ApoE2 (Arg158→Cys) on cholesterol levels and atherosclerosis in ApoE-deficient mice
-
Van Eck M., Herijgers N., Van Dijk K.W., et al. Effect of macrophage-derived mouse ApoE, human ApoE3-Leiden, and human ApoE2 (Arg158→Cys) on cholesterol levels and atherosclerosis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 2000, 20:119-127.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 119-127
-
-
Van Eck, M.1
Herijgers, N.2
Van Dijk, K.W.3
-
43
-
-
0021720626
-
Familial apolipoprotein AI and apolipoprotein CIII deficiency. Subclass distribution, composition, and morphology of lipoproteins in a disorder associated with premature atherosclerosis
-
Forte T.M., Nichols A.V., Krauss R.M., Norum R.A. Familial apolipoprotein AI and apolipoprotein CIII deficiency. Subclass distribution, composition, and morphology of lipoproteins in a disorder associated with premature atherosclerosis. J Clin Invest 1984, 74:1601-1613.
-
(1984)
J Clin Invest
, vol.74
, pp. 1601-1613
-
-
Forte, T.M.1
Nichols, A.V.2
Krauss, R.M.3
Norum, R.A.4
-
44
-
-
0021864604
-
Apo E-containing lipoproteins in low or high density lipoprotein deficiency
-
Gibson J.C., Rubinstein A., Brown W.V., et al. Apo E-containing lipoproteins in low or high density lipoprotein deficiency. Arteriosclerosis 1985, 5:371-380.
-
(1985)
Arteriosclerosis
, vol.5
, pp. 371-380
-
-
Gibson, J.C.1
Rubinstein, A.2
Brown, W.V.3
|