Anthrax lethal toxin-mediated disruption of endothelial VE-cadherin is attenuated by inhibition of the Rho-associated kinase pathway

Toxins

Volumn 3, Issue 10, 2011, Pages 1278-1293

  Warfel, Jason M ^a,b   D'Agnillo, Felice ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Actin stress fibers; Adherens junction; Anthrax lethal toxin; Barrier function; Cadherin; Vascular endothelium

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACTIN; ALBUMIN; ANTHRAX TOXIN; BETA CATENIN; MESSENGER RNA; MYOSIN LIGHT CHAIN; RHO KINASE; VASCULAR ENDOTHELIAL CADHERIN;

ARTICLE; ATTENUATION; CELL JUNCTION; CELL STRUCTURE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME MODIFICATION; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STRESS FIBER; TOXIN ANALYSIS; VE CADHERIN GENE;

ADHERENS JUNCTIONS; ANTIGENS, BACTERIAL; ANTIGENS, CD; BACTERIAL TOXINS; CADHERINS; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; FLUORESCEIN-5-ISOTHIOCYANATE; HUMANS; PROTEIN KINASE INHIBITORS; RHO-ASSOCIATED KINASES; RNA, MESSENGER; SERUM ALBUMIN;

EID: 80054985548     PISSN: None     EISSN: 20726651     Source Type: Journal    
DOI: 10.3390/toxins3101278     Document Type: Article

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